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Ceritinib

5-chloro-2-N-(5-methyl-4-piperidin-4-yl-2-propan-2-yloxyphenyl)-4-N-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine

SMILES: CC1=CC(=C(C=C1C2CCNCC2)OC(C)C)NC3=NC=C(C(=N3)NC4=CC=CC=C4S(=O)(=O)C(C)C)Cl

InChIKey: VERWOWGGCGHDQE-UHFFFAOYSA-N

Synonyms: ceritinib, LDK378, 1032900-25-6, ZYKADIA, NVP-LDK378-NX

Classification: Anticancer agents

Action: Cytotoxic

Mechanism: Signal transduction inhibitor

Date of approval: April 1, 2014

Ref Target proteins for cytotoxic compounds