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Brigatinib

5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidine-2,4-diamine

SMILES: CN1CCN(CC1)C2CCN(CC2)C3=CC(=C(C=C3)NC4=NC=C(C(=N4)NC5=CC=CC=C5P(=O)(C)C)Cl)OC

InChIKey: AILRADAXUVEEIR-UHFFFAOYSA-N

Synonyms: Brigatinib, 1197953-54-0, UNII-HYW8DB273J, Brigatinib [USAN], ALUNBRIG

Classification: Anticancer agents

Action: Cytotoxic

Mechanism: Signal transduction inhibitor

Date of approval: April 1, 2017

Ref Target proteins for cytotoxic compounds