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Abemaciclib

N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine

SMILES: CCN1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F

InChIKey: UZWDCWONPYILKI-UHFFFAOYSA-N

Synonyms: Abemaciclib, 1231929-97-7, LY2835219, LY-2835219, Verzenio

Classification: Anticancer agents

Action: Cytotoxic

Mechanism: Signal transduction inhibitor

Date of approval: Sept. 1, 2017

Ref Target proteins for cytotoxic compounds