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Recent literature: Integrase inhibitor
Date Journal Article title
2019 Nov AIDS Time to rethink endpoints for new antiretroviral regimen registration? HIV RNA re-pression in the ADVANCE trial.
2019 Nov Med Mal Infect High rates of antiretroviral coverage and virological pression in HIV-1-infected children and adolescents.
2019 Nov Infection Weight gain in antiretroviral therapy-naive HIV-1-infected patients starting a regimen including an integrase strand transfer inhibitor or darunavirritonavir.
2019 Nov J Matern Fetal Neonatal Med Comparison of two combined antiretroviral treatment regimens in the management of HIV in pregnancy: an observational study.
2019 Nov Obstet Gynecol Combination Antiretroviral Therapy and Hypertensive Disorders of Pregnancy.
2019 Oct Cytokine The impact of integrase inhibitor-based regimens on markers of inflammation among HIV naïve patients.
2019 PLoS One CCR5 receptor antagonism inhibits hepatitis C virus (HCV) replication in vitro.
2019 Open Forum Infect Dis Recent Trends and Effectiveness of Antiretroviral Regimens Among Men Who Have Sex With Men Living With HIV in the United States: The Multicenter AIDS Cohort Study (MACS) 2008-2017.
2019 Oct Curr Opin HIV AIDS HIV treatment and prevention 2019: current standards of care.
2012 LiverTox: Clinical and Re... Antiviral Agents
2012 LiverTox: Clinical and Re... Dolutegravir
2012 LiverTox: Clinical and Re... Raltegravir
2012 LiverTox: Clinical and Re... Bictegravir
2012 LiverTox: Clinical and Re... Elvitegravir
2019 Oct J Antimicrob Chemother Surveillance of HIV-1 primary infections in France from 2014 to 2016: toward stable resistance, but higher diversity, clustering and virulence?
2019 Oct ACS Infect Dis Rational Design of Doravirine: From Bench to Patients.
2019 Oct J Antimicrob Chemother Integrase strand transfer inhibitor (INSTI)-resistance mutations for the surveillance of transmitted HIV-1 drug resistance.
2019 Oct J Antimicrob Chemother Is immune recovery different depending on the use of integrase strand transfer inhibitor-, non-nucleoside reverse transcriptase- or boosted protease inhibitor-based regimens in antiretroviral-naive HIV-infected patients?
2019 Oct Molecules Discovery of Novel Integrase Inhibitors Acting outside the Active Site Through High-Throughput Screening.
2019 Oct J Virol HIV-2 depletes CD4 T cells through pyroptosis despite Vpx-dependent degradation of SAMHD1.
2019 Nov AIDS Acute myocarditis after switch to dolutegravir: a reminder of potential toxicity of integrase inhibitor-including HAART.
2019 Sep AIDS Antiretroviral therapy adherence among treatment-naive HIV-infected patients: A retrospective cohort study.
2019 Sep AIDS No overall change in the rate of weight gain after switching to an integrase-inhibitor in virologically pressed adults with HIV.
2019 Dec Eur J Med Chem Discovery of 2-isoxazol-3-yl-acetamide analogues as heat shock protein 90 (HSP90) inhibitors with significant anti-HIV activity.
2019 Sep Curr HIV Res Integrase Inhibitor-Based Antiretroviral Therapy Among Women Living with HIV: Data from the OPERA Cohort.
2019 Expert Opin Drug Metab To... Current and emerging non-nucleoside reverse transcriptase inhibitors (NNRTIs) for HIV-1 treatment.
2019 Sep Curr Comput Aided Drug Des Quantitative Structure - Activity Relationship Study for HIV-1 LEDGFp75 inhibitors.
2019 AIDS Rev Is Antiretroviral Two-Drug Regimen the New Standard for HIV Treatment in Naive Patients?
2019 Clin Drug Investig Reduction of Immune Activation and Partial Recovery of Staphylococcal Enterotoxin B-Induced Cytokine Production After Switching to an Integrase Strand Transfer Inhibitor-Containing Regimen: Results from an Observational Cohort Study.
2020 Jan J Pharm Biomed Anal Determination of raltegravir and raltegravir glucuronide in human plasma and urine by LC-MSMS with application in a maternal-fetal pharmacokinetic study.
2019 Sep Transpl Infect Dis Successful optimization of antiretroviral regimens in treatment-experienced people living with HIV undergoing liver transplantation.
2019 EClinicalMedicine The potential impact of initiating antiretroviral therapy with integrase inhibitors on HIV transmission risk in British Columbia, Canada.
2019 Oct AIDS Res Hum Retroviruses Perspectives on the Barrier to Resistance for Dolutegravir + Lamivudine, a Two-Drug Antiretroviral Therapy for HIV-1 Infection.
2019 Nov J Antimicrob Chemother Incidence and risk factors for liver enzyme elevation among naive HIV-1-infected patients receiving ART in the ICONA cohort.
2019 Aug Clin Infect Dis Weight Gain Associated with Integrase Stand Transfer Inhibitor Use in Women.
2019 Oct AIDS Lack of HIV-1 integrase inhibitor resistance among 392 antiretroviral-naïve individuals in a tertiary care hospital in Beijing, China.
2019 Front Pharmacol Raltegravir Attenuates Experimental Pulmonary Fibrosis iIn Vitroi and iIn Vivoi.
2019 Front Microbiol Inhibition of HTLV-1 Infection by HIV-1 First- and Second-Generation Integrase Strand Transfer Inhibitors.
2019 Oct J Biol Chem Multifaceted HIV integrase functionalities and therapeutic strategies for their inhibition.
2019 Aug Med Chem Novel benzoxazin-3-one derivatives: Design, synthesis, molecular modeling, anti-HIV-1 and integrase inhibitory assay.
2019 PLoS One Placental transfer and tissue accumulation of dolutegravir in the ex vivo human cotyledon perfusion model.
2019 Int J Antimicrob Agents Meta-analysis and systematic review of the efficacy and resistance for human immunodeficiency virus type 1 integrase strand transfer inhibitors.
2019 Infect Dis Clin North Am Key Principles of Antiretroviral Pharmacology.
2019 J Med Virol Antiviral activity of HIV-1 integrase strand-transfer inhibitors against mutants with integrase resistance-associated mutations and their frequency in treatment-naïve individuals.
2019 Drug Des Devel Ther Durability of INI-containing regimens after switching from PI-containing regimens: a single-centre cohort of drug-experienced HIV-infected jects.
2019 Sep AIDS Drug resistance and optimizing dolutegravir regimens for adolescents and young adults failing antiretroviral therapy.
2019 Sep Cancer Res Therapeutic Targeting of Aldolase A Interactions Inhibits Lung Cancer Metastasis and Prolongs Survival.
2019 Nov J Acquir Immune Defic Syndr Antiretroviral Adherence Level Necessary for HIV Viral Suppression Using Real-World Data.
2019 Clin Exp Nephrol Prevalence of chronic kidney disease among HIV-1-infected patients receiving a combination antiretroviral therapy.
2019 Curr Med Res Opin Incidence of select chronic comorbidities among a population-based cohort of HIV-positive individuals receiving highly active antiretroviral therapy.
2019 Intervirology HIV-1 Drug Resistance Mutations among Antiretroviral Drug-Experienced Patients in the South of Iran.
2019 Intervirology HIV-1 Integrase Resistance among Highly Antiretroviral Experienced Patients from Morocco.
2019 J Med Virol Homeostatic model assessment for insulin resistance index trajectories in HIV-infected patients treated with different first-line antiretroviral regimens.
2019 Jul J Neurovirol Hepatitis C virus-related factors associated WITH cognitive performance in HIV-HCV-coinfected patients.
2019 Nov J Antimicrob Chemother A systematic review of the genetic mechanisms of dolutegravir resistance.
2019 Sep J Antimicrob Chemother Dual therapy combining raltegravir with etravirine maintains a high level of viral pression over 96 weeks in long-term experienced HIV-infected individuals over 45 years on a PI-based regimen: results from the Phase II ANRS 163 ETRAL study.
2019 Medicine (Baltimore) Risk of elevation of serum creatine kinase among HIV-positive individuals receiving dolutegravir-based combination antiretroviral therapy.
2019 Infect Dis Clin North Am Initial Antiretroviral Therapy in an Integrase Inhibitor Era: Can We Do Better?
2019 Infect Dis (Lond) Improvement in liver steatosis after the switch from a ritonavir-boosted protease inhibitor to raltegravir in HIV-infected patients with non-alcoholic fatty liver disease.
2019 Lancet HIV Correlates of HIV RNA concentrations in cerebrospinal fluid during antiretroviral therapy: a longitudinal cohort study.
2019 Jul J Acquir Immune Defic Syndr Impact of Integrase Inhibition Compared With Nonnucleoside Inhibition on HIV Reservoirs in Lymphoid Tissues.
2019 J Pharmacol Exp Ther Mechanistic Basis of Cabotegravir-Glucuronide Disposition in Humans.
2019 AIDS Res Hum Retroviruses Trends in HIV-1 Drug Resistance Mutations from a U.S. Reference Laboratory from 2006 to 2017.
2019 Drug Metab Dispos Clinical Extrapolation of the Effects of Dolutegravir and Other HIV Integrase Inhibitors on Folate Transport Pathways.
2019 May BMC Infect Dis Comparative efficacy and safety of dolutegravir relative to common core agents in treatment-naïve patients infected with HIV-1: a systematic review and network meta-analysis.
2019 J Pharm Pharmacol Antiretroviral agents in pre-exposure prophylaxis: emerging and advanced trends in HIV prevention.
2019 Jul J Control Release 2-Hydroxypropyl-β-cyclodextrin-enhanced pharmacokinetics of cabotegravir from a nanofluidic implant for HIV pre-exposure prophylaxis.
2019 Drugs Today (Barc) Dolutegravir plus lamivudine dual therapy - a new option for initial antiretroviral therapy.
2019 Antimicrob Agents Chemother Interpretation of Drug Interactions between Dolutegravir and Artemether-Lumefantrine or Artesunate-Amodiaquine.
2019 May Clin Infect Dis Cabotegravir is Not Associated with Weight Gain in HIV-uninfected Individuals in HPTN 077.
2019 Open Forum Infect Dis INSTI-Based Triple Regimens in Treatment-Naïve HIV-Infected Patients Are Associated With HIV-RNA Viral Load Suppression at Ultralow Levels.
2019 May Clin Infect Dis Greater Weight Gain in Treatment Naïve Persons Starting Dolutegravir-Based Antiretroviral Therapy.
2019 Aug AIDS E157Q integrase strand-transfer inhibitor stitution in patients with acuterecent HIV infection.
2019 Expert Opin Pharmacother Pharmacotherapeutic management of HIV in transplant patients.
2019 Int J STD AIDS Safety and efficacy of dolutegravir in hemodialysis.