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Recent literature: Integrase inhibitor
Date Journal Article title
2020 Mar JMIR Res Protoc Innovative Approaches to Obtain Minors' Consent for Biomedical HIV Prevention Trials: Multi-Site Quasi-Experimental Study of Adolescent and Parent Perspectives.
2020 Mar J Neuroimmune Pharmacol Associations between Antiretrovirals and Cognitive Function in Women with HIV.
2020 Mar J Antimicrob Chemother Antiretroviral concentrations in the presence and absence of valproic acid.
2020 Mar J Antimicrob Chemother Five-year follow-up of patients enrolled in the NEAT 001ANRS 143 randomized clinical trial: NEAT 001ANRS 143 LONG TERM study.
2020 Mar J Antimicrob Chemother Impact of first-line antiretroviral therapy regimens on the restoration of the CD4CD8 ratio in the CNICS cohort.
2020 Mar J Pharm Biomed Anal Measurement of total and unbound bictegravir concentrations in plasma and cerebrospinal fluid by UHPLC-MSMS.
2020 Mar BMJ Open Antiretroviral drug class and anaemia risk in the current treatment era among people living with HIV in the USA: a clinical cohort study.
2020 Mar Pediatr Infect Dis J Outcomes of Integrase Inhibitor-based Antiretroviral Therapy in a Clinical Cohort of Treatment-experienced Children, Adolescents and Young Adults With HIV Infection.
2020 Mar Clin Infect Dis The integrase inhibitors dolutegravir and raltegravir exert pro-adipogenic and profibrotic effects and induce insulin resistance in humansimian adipose tissue and human adipocytes.
2020 HIV Res Clin Pract Presence of V72I, G123S and R127K Integrase Inhibitor polymorphisms could reduce ART effectiveness: a retrospective longitudinal study.
2020 Mar Antiviral Res The broad spectrum antiviral ivermectin targets the host nuclear transport importin αβ1 heterodimer.
2020 Mar J Antimicrob Chemother Effectiveness of boosted darunavir plus rilpivirine in patients with long-lasting HIV-1 infection: DARIL study.
2020 Mar N Engl J Med Long-Acting Cabotegravir and Rilpivirine for Maintenance of HIV-1 Suppression.
2020 Mar AIDS Res Hum Retroviruses Circulating HIV-1 integrase genotypes in Tanzania: Implication on the introduction of Integrase Inhibitors-based ART regimen.
2020 Ethiop J Health Sci Characterization of HIV-1 Integrase Gene and Resistance Associated Mutations Prior to Roll out of Integrase Inhibitors by Kenyan National HIV-Treatment Program in Kenya.
2020 Feb J Antimicrob Chemother High prevalence of integrase mutation L74I in West African HIV-1 types prior to integrase inhibitor treatment.
2020 Mar J Chem Theory Comput Combining Alchemical Transformation with a Physical Pathway to Accelerate Absolute Binding Free Energy Calculations of Charged Ligands to Enclosed Binding Sites.
2020 Feb Clin Infect Dis Risk Factors for Weight Gain Following Switch to Integrase Inhibitor-Based Antiretroviral Therapy.
2020 Feb J Mol Biol A Peptide Derived from Lens Epithelium-Derived Growth Factor Stimulates HIV-1 DNA Integration and Facilitates Intasome Structural Studies.
2020 Int J STD AIDS Development of gynecomastia following initiation of bictegraviremtricitabinetenofovir alafenamide.
2020 Lancet HIV Updated assessment of risks and benefits of dolutegravir versus efavirenz in new antiretroviral treatment initiators in -Saharan Africa: modelling to inform treatment guidelines.
2020 HIV Med The potential role of bictegraviremtricitabinetenofovir alafenamide (BICFTCTAF) single-tablet regimen in the expanding spectrum of fixed-dose combination therapy for HIV.
2020 Apr J Pharm Biomed Anal HPLC-MSMS method for the simultaneous quantification of dolutegravir, elvitegravir, rilpivirine, darunavir, ritonavir, raltegravir and raltegravir-β-d-glucuronide in human plasma.
2020 Feb Science Structural basis of second-generation HIV integrase inhibitor action and viral resistance.
2020 Feb Science Structural basis for strand-transfer inhibitor binding to HIV intasomes.
2020 Curr HIV Res Binding Insight of Anti-HIV Phytocompounds with Prime Targets of HIV: A Molecular Dynamics Simulation Analysis.
2020 Curr Opin HIV AIDS Antiretroviral therapy in older people with HIV.
2020 Jan J Antimicrob Chemother Efficacy of intermittent short cycles of integrase inhibitor-based maintenance ART in virologically pressed HIV patients.
2020 Jan J Antimicrob Chemother HIV MDR is still a relevant issue despite its dramatic drop over the years.
2020 PLoS One HIV antiretroviral drugs, dolutegravir, maraviroc and ritonavir-boosted atazanavir use different pathways to affect inflammation, senescence and insulin sensitivity in human coronary endothelial cells.
2020 Jan J Infect Dis Expanded Spectrum of Antiretroviral-Selected Mutations in Human Immunodeficiency Virus Type 2.
2020 Pharmacoepidemiol Drug Saf Comedication prescription patterns and potential for drug-drug interactions with antiretroviral therapy in people living with human immunodeficiency virus type 1 infection in Germany.
2020 Expert Opin Ther Pat A literature review of the patent application publications on cabotegravir - an HIV integrase strand transfer inhibitor.
2020 Mar J Virol Capsid-Labelled HIV To Investigate the Role of Capsid during Nuclear Import and Integration.
2020 Int J Antimicrob Agents Retrospective study on the outcome of two-drug regimens based on dolutegravir plus one reverse transcriptase inhibitor in virologically-pressed HIV-infected patients.
2020 Mar J Acquir Immune Defic Syndr Uptake and Discontinuation of Integrase Inhibitors (INSTIs) in a Large Cohort Setting.
2020 Jan MMWR Morb Mortal Wkly Rep Neural Tube Defects in Pregnancies Among Women With Diagnosed HIV Infection - 15 Jurisdictions, 2013-2017.
2020 Jan J Acquir Immune Defic Syndr Raltegravir (RAL) in neonates: Dosing, pharmacokinetics (PK), and safety in HIV-1 exposed neonates at risk of infection (IMPAACT P1110).
2020 Jan Sex Transm Infect Anal dysplasia and HIV shedding in ART-treated men.
2020 Jan Clin Infect Dis Efficacy and Safety of Switching to DolutegravirLamivudine Fixed-Dose Two-Drug Regimen Versus Continuing a Tenofovir Alafenamide-Based Three- or Four-Drug Regimen for Maintenance of Virologic Suppression in Adults With HIV-1: Phase 3, Randomized, Non-inferiority TANGO Study.
2019 Infect Chemother Comparison of Characteristics and Survival between Prospective and Retrospective Korea Human Immunodeficiency VirusAcquired Immune Deficiency Syndrome Cohort Studies.
2020 Apr AIDS Challenges of scale-up to dolutegravir-based regimens in -Saharan Africa.
2020 Apr AIDS Switch from tenofovir disoproxil fumarate to raltegravir is not associated with weight gain over 96 weeks.
2020 Infection Pregnancy and neonatal outcomes in women with HIV-1 exposed to integrase inhibitors, protease inhibitors and non-nucleoside reverse transcriptase inhibitors: an observational study.
2019 EClinicalMedicine Immune reconstitution inflammatory syndrome in HIV infected late presenters starting integrase inhibitor containing antiretroviral therapy.
2019 EClinicalMedicine Initiation of antiretroviral therapy with integrase strand-transfer inhibitor-based regimens and reduction of the risk of horizontal transmission of HIV-1.
2019 Dec J Med Virol Analyses of HIV-1 integrase gene sequences among treatment-naive patients in the Eastern Cape, South Africa.
2020 Int J Infect Dis Weight gain and dyslipidemia among virally pressed HIV-positive patients switching to co-formulated elvitegravircobicistatemtricitabinetenofovir alafenamide.
2020 Jan Acc Chem Res Cutting into the Substrate Dominance: Pharmacophore and Structure-Based Approaches toward Inhibiting Human Immunodeficiency Virus Reverse Transcriptase-Associated Ribonuclease H.
2019 Oct Pharmacoeconomic Review R...
2020 Feb AIDS Time to rethink endpoints for new clinical trials of antiretrovirals? Long-term re-pression of HIV RNA with integrase inhibitors.
2020 Infect Dis (Lond) No progression of clinical atherosclerosis in HIV-infected patients starting an initial regimen including tenofovir alafenamideemtricitabine plus raltegravir, dolutegravir or elvitegravircobicistat during a two-year follow-up.
2020 Mar J Antimicrob Chemother Pharmacokinetics and antiviral activity of cabotegravir and rilpivirine in cerebrospinal fluid following long-acting injectable administration in HIV-infected adults.
2020 Drugs DolutegravirLamivudine Single-Tablet Regimen: A Review in HIV-1 Infection.
2020 Mar J Antimicrob Chemother Prediction of dolutegravir pharmacokinetics and dose optimization in neonates via physiologically based pharmacokinetic (PBPK) modelling.
2019 Dec Infez Med Clinical pharmacology of the single tablet regimen bictegraviremtricitabinetenofovir alafenamide (BICFTCTAF).
2019 Drugs Today (Barc) Bictegravir, a novel integrase inhibitor for the treatment of HIV infection.
2019 Dec Molecules Characterization of Nine Compounds Isolated from the Acid Hydrolysate of iLonicera fulvotomentosai Hsu et S. C. Cheng and Evaluation of Their In Vitro Activity towards HIV Protease.
2020 Jan AIDS Res Hum Retroviruses HIV-1 Integrase Diversity and Resistance-Associated Mutations and Polymorphisms Among Integrase Strand Transfer Inhibitor-Naive HIV-1 Patients from Cameroon.
2020 Feb Antimicrob Agents Chemother Detectability of HIV Residual Viremia despite Therapy Is Highly Associated with Treatment with a Protease Inhibitor-Based Combination Antiretroviral Therapy.
2020 Antiviral Res Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors.
2020 Jan J Acquir Immune Defic Syndr Forecasting Prevalence of HIV-1 Integrase Strand Transfer Inhibitor (INSTI) Drug Resistance: A Modeling Study.
2019 Medicine (Baltimore) Non-traumatic perforation of the jejunum in a human immunodeficiency virus-infected patient receiving combination antiretroviral therapy: A case report.
2020 Int J STD AIDS Changes in HIV antiretroviral prescribing practices in the United States.
2020 Curr Opin Infect Dis Weight gain and integrase inhibitors.
2020 J Biomol Struct Dyn Dual inhibitor design for HIV-1 reverse transcriptase and integrase enzymes: a molecular docking study.
2019 Nov Planta Up-regulation of microRNA targets correlates with symptom severity in Citrus sinensis plants infected with two different isolates of citrus psorosis virus.
2019 Nov J Clin Med Impact of Antiretroviral Therapy on the Risk of Recurrence in HIV-1 Infected Patients with Kaposi Sarcoma: A Multicenter Cohort Experience.
2019 Obstet Gynecol Combination Antiretroviral Therapy and Hypertensive Disorders of Pregnancy.
2020 Mar AIDS Virological and immunological impact of integrase inhibitor-based regimens initiated during primary HIV-1 infection.
2020 Feb Bioorg Med Chem Lett Heterocycle amide isosteres: An approach to overcoming resistance for HIV-1 integrase strand transfer inhibitors.
2020 Jan Bioorg Med Chem Design, synthesis and biological evaluation of imidazole and oxazole fragments as HIV-1 integrase-LEDGFp75 disruptors and inhibitors of microbial pathogens.
2019 PLoS One Genetic diversity and antiretroviral resistance-associated mutation profile of treated and naive HIV-1 infected patients from the Northwest and Southwest regions of Cameroon.
2019 HIV AIDS (Auckl) Dolutegravir And Lamivudine Combination For The Treatment Of HIV-1 Infection.
2019 Nov Sci Rep Similar plasma lipidomic profile in people living with HIV treated with a darunavir-based or an integrase inhibitor-based antiretroviral therapy.