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Recent literature: Integrase inhibitor
Date Journal Article title
2019 Ther Adv Infect Dis Optimal treatment of HIV-associated neurocognitive disorders: myths and reality. A critical review.
2019 Int J STD AIDS Efficacy and safety of abacavirlamivudine with raltegravir in treatment-experienced and treatment-naïve patients with HIV-1 infection: an observational, retrospective, multi-centre study.
2019 Apr ACS Med Chem Lett Synthesis and Anti-HIV Profile of a Novel Tetrahydroindazolylbenzamide Derivative Obtained by Oxazolone Chemistry.
2019 Apr Antiviral Res A potential long-acting bictegravir loaded nano-drug delivery system for HIV-1 infection: A proof-of-concept study.
2019 Apr J Infect Chemother A model-based comparative meta-analysis of the efficacy of dolutegravir-based and efavirenz-based regimens in HIV-infected patients.
2019 Apr Clin Drug Investig Paediatric Integrase Inhibitor Use in a Real-Life Setting: A Single-Centre Cohort Experience 2009-2018.
2019 Apr Proc Natl Acad Sci U S A Mutations in the HIV-1 envelope glycoprotein can broadly rescue blocks at multiple steps in the virus replication cycle.
2019 Apr Int J STD AIDS Ritonavir- or cobicistat-boosted antiretroviral therapy and direct oral anticoagulants: A case for apixaban.
2018 Oct Clinical Review Report: B...
2018 Oct Pharmacoeconomic Review R...
2019 Mar Pharm Res Antiretroviral Hydrophobic Core Graft-Copolymer Nanoparticles: The Effectiveness against Mutant HIV-1 Strains and in Vivo Distribution after Topical Application.
2019 Mar J Acquir Immune Defic Syndr Evaluation of Neural Tube Defects (NTD) After Exposure to Raltegravir During Pregnancy.
2019 Mar Int J Antimicrob Agents Effectiveness of switching from protease inhibitors to dolutegravir in combination with nucleoside reverse-transcriptase inhibitors as maintenance antiretroviral therapy among HIV-positive patients.
2019 AIDS Rev Neuropsychiatric Adverse Events with Dolutegravir and Other Integrase Strand Transfer Inhibitors
2019 Mar Antivir Ther Effect of rifabutin on the pharmacokinetics of oral cabotegravir in healthy jects.
2019 Open Forum Infect Dis Prevalence of Human Immunodeficiency Virus-1 Integrase Strand Transfer Inhibitor Resistance in British Columbia, Canada Between 2009 and 2016: A Longitudinal Analysis.
2019 Mar J Acquir Immune Defic Syndr Impact of Integrase Inhibition compared to non-nucleoside inhibition on HIV reservoirs in Lymphoid Tissues.
2019 Mar Antivir Ther Tenofovir and emtricitabine resistance among antiretroviral-naive patients in the Canadian Observational Cohort Collaboration: implications for PrEP.
2019 Mar Mini Rev Med Chem Recent Advances towards Treatment of HIV: Synthesis and SAR Studies.
2019 PLoS One Role of pretreatment variables on plasma HIV RNA value at the sixth month of antiretroviral therapy including all first line drugs in HIV naïve patients: A path analysis approach.
2019 Evid Based Complement Alt... Flavonol 7-iOi-Glucoside Herbacitrin Inhibits HIV-1 Replication through Simultaneous Integrase and Reverse Transcriptase Inhibition.
2019 Feb Clin Pharmacol Drug Dev A Phase 1 Study to Evaluate the Pharmacokinetics and Safety of Cabotegravir in Patients With Hepatic Impairment and Healthy Matched Controls.
2019 Feb Clin Pharmacol Drug Dev A Phase I Study to Evaluate the Pharmacokinetics and Safety of Cabotegravir in Adults With Severe Renal Impairment and Healthy Matched Control Participants.
2019 Drug Metab Dispos Mechanistic Assessment of Extrahepatic Contributions to Glucuronidation of Integrase Strand Transfer Inhibitors.
2019 Feb Antimicrob Agents Chemother Comparison of the Antiviral Activity of Bictegravir Against HIV-1 and HIV-2 Isolates and Integrase Inhibitor-Resistant HIV-2 Mutants.
2019 Jan J Virus Erad Immunological profile of an infant treated with integrase inhibitor from the neonatal period.
2019 J Int Assoc Provid AIDS Care Maintenance of Viral Suppression after Optimization Therapy from Etravirine Plus Raltegravir to Rilpivirine Plus Dolutegravir in HIV-1-Infected Patients.
2019 Feb Virus Genes Integrase strand transfer inhibitor-based regimen is related with a limited HIV-1 V3 loop evolution in clinical practice.
2019 Apr AIDS Res Hum Retroviruses Absence of Integrase Strand Transfer Inhibitor Associated Resistance in Antiretroviral Therapy Naïve and Experienced Individuals from Western India.
2019 Feb J Antimicrob Chemother Resistance to integrase inhibitors: a national study in HIV-1-infected treatment-naive and -experienced patients.
2019 Internist (Berl) [Modern HIV treatment].
2019 Feb Clin Transplant Solid Organ Transplantation in the HIV-Infected Patient: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice.
2019 Feb Retrovirology Replication competence of virions induced from CD4+ lymphocytes latently infected with HIV.
2019 Feb J Antimicrob Chemother Stable prevalence of transmitted drug resistance mutations and increased circulation of non-B types in antiretroviral-naive chronically HIV-infected patients in 20152016 in France.
2019 Feb J Neurovirol Morphine counteracts the antiviral effect of antiretroviral drugs and causes upregulation of p62SQSTM1 and histone-modifying enzymes in HIV-infected astrocytes.
2019 Feb J Biomol Struct Dyn Effective prediction model and determination of binding residues influential for inhibitors targeting HIV-1 integrase-LEDGFp75 interface by employing solvent accessible surface area energy as key determinant.
2019 Apr Toxicol Appl Pharmacol The inhibitory effect of antiretroviral drugs on the L-carnitine uptake in human placenta.
2019 Pharmacotherapy Effectiveness of OnceDay Dolutegravir Plus Boosted Darunavir as a Switch Strategy in Heavily Treated Patients with Human Immunodeficiency Virus.
2019 Expert Opin Pharmacother Bictegravir in a fixed-dose tablet with emtricitabine and tenofovir alafenamide for the treatment of HIV infection: pharmacology and clinical implications.
2019 HIV Med Discontinuation of dolutegravir, elvitegravircobicistat and raltegravir because of toxicity in a prospective cohort.
2019 Apr J Antimicrob Chemother Progressive increases in fat mass occur in adults living with HIV on antiretroviral therapy, but patterns differ by sex and anatomic depot.
2019 Open Forum Infect Dis Development of the R263K Mutation to Dolutegravir in an HIV-1 Subtype D Virus Harboring 3 Class-Drug Resistance.
2018 Jun Pharmacoeconomic Review R...
2019 Clin Drug Investig HIV Integrase Inhibitor Pharmacogenetics: An Exploratory Study.
2019 Jan BMC Public Health HIV treatment regimens and adherence to national guidelines in Australia: an analysis of dispensing data from the Australian pharmaceutical benefits scheme.
2019 Antiviral Res Discovery of 4-oxoquinolines, a new chemical class of anti-HIV-1 compounds.
2019 Br J Clin Pharmacol Atrial fibrillation and human immunodeficiency virus type-1 infection: a systematic review. Implications for anticoagulant and antiarrhythmic therapy.
2019 Mar J Virol PF74 Inhibits HIV-1 Integration by Altering the Composition of the Preintegration Complex.
2018 AIDS Rev Overcoming Obstacles in Lipid-lowering Therapy in Patients with HIV - A Systematic Review of Current Evidence.
2019 Mar J Antimicrob Chemother Integrase strand transfer inhibitors and neuropsychiatric adverse events in a large prospective cohort.
2018 Heliyon Relationship between HIV integrase polymorphisms and integrase inhibitor susceptibility: An iin silicoi analysis.
2018 Lancet HIV Safety and efficacy at 240 weeks of different raltegravir formulations in children with HIV-1: a phase 12 open label, non-randomised, multicentre trial.
2019 Lancet HIV Risks and benefits of dolutegravir-based antiretroviral drug regimens in -Saharan Africa: a modelling study.
2018 Open Forum Infect Dis Canary in the Coal Mine? Transmitted Mutations Conferring Resistance to All Integrase Strand Transfer Inhibitors in a Treatment-Naive Patient.
2018 PLoS Med Raltegravir-intensified initial antiretroviral therapy in advanced HIV disease in Africa: A randomised controlled trial.
2019 Mar AIDS Success and failure of initial antiretroviral therapy in adults: an updated systematic review.
2018 HIV AIDS (Auckl) Profile of bictegraviremtricitabinetenofovir alafenamide fixed dose combination and its potential in the treatment of HIV-1 infection: evidence to date.
2019 HIV Med Prevalence and determinants of resistance mutations in HIV-1-infected patients exposed to integrase inhibitors in a large Italian cohort.
2018 Drugs BictegravirEmtricitabineTenofovir Alafenamide: A Review in HIV-1 Infection.
2018 HIV Clin Trials Sleep and neuropsychological performance in HIV+ jects on efavirenz-based therapy and response to switch in therapy.
2018 HIV Clin Trials Satisfaction and acceptability of cabotegravir long-acting injectable suspension for prevention of HIV: Patient perspectives from the ECLAIR trial.
2018 J Photochem Photobiol B Efficient discrimination of natural stereoisomers of chicoric acid, an HIV-1 integrase inhibitor.
2018 Medicine (Baltimore) Integrase inhibitor-based regimens result in more rapid virologic pression rates among treatment-naïve human immunodeficiency virus-infected patients compared to non-nucleoside and protease inhibitor-based regimens in a real-world clinical setting: A retrospective cohort study.
2018 Nov Med Mal Infect Which antiretrovirals should be prescribed as first-line treatments? Changes over the past 10 years in France.
2018 PLoS Med Safety, tolerability, and pharmacokinetics of long-acting injectable cabotegravir in low-risk HIV-uninfected individuals: HPTN 077, a phase 2a randomized controlled trial.
2018 Drugs DolutegravirRilpivirine: A Review in HIV-1 Infection.
2018 Nov Angew Chem Int Ed Engl Corrigendum: 7-Step Flow Synthesis of the HIV Integrase Inhibitor Dolutegravir.
2018 Nov Eur J Drug Metab Pharmaco... Pharmacokinetics and Pharmacodynamics of Cabotegravir, a Long-Acting HIV Integrase Strand Transfer Inhibitor.
2019 Jan J Virol Dolutegravir Monotherapy of Simian Immunodeficiency Virus-Infected Macaques Selects for Several Patterns of Resistance Mutations with Variable Virological Outcomes.
2019 Feb J Antimicrob Chemother Predicted antiviral activity of tenofovir versus abacavir in combination with a cytosine analogue and the integrase inhibitor dolutegravir in HIV-1-infected South African patients initiating or failing first-line ART.
2019 Mar J Clin Endocrinol Metab Changes in Body Fat Distribution in Antiretroviral-Naive HIV-Positive Individuals Initiating Current ART Regimens.
2018 HIV Clin Trials Association of raltegravir use with long-term health outcomes in HIV-infected patients: an observational post-licensure safety study in a large integrated healthcare system.
2018 Oct J Pediatric Infect Dis Soc Compromise of Second-Line Antiretroviral Therapy Due to High Rates of Human Immunodeficiency Virus Drug Resistance in Mozambican Treatment-Experienced Children With Virologic Failure.
2019 Antivir Ther Increased dose of dolutegravir as a potential rescue therapy in multi-experienced patients.
2018 Nov J Med Chem Discovery and Structure-Activity-Relationship Study of N-Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-β-d-ribose 2'-Oxidase.