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Recent literature: Integrase inhibitor
Date Journal Article title
2019 PLoS One Placental transfer and tissue accumulation of dolutegravir in the ex vivo human cotyledon perfusion model.
2019 Infect Dis Clin North Am Key Principles of Antiretroviral Pharmacology.
2019 Aug J Med Virol Antiviral activity of HIV-1 integrase strand-transfer inhibitors against mutants with integrase resistance-associated mutations and their frequency in treatment-naïve individuals.
2019 Drug Des Devel Ther Durability of INI-containing regimens after switching from PI-containing regimens: a single-centre cohort of drug-experienced HIV-infected jects.
2019 Sep AIDS Drug resistance and optimizing dolutegravir regimens for adolescents and young adults failing antiretroviral therapy.
2019 Jul Cancer Res Therapeutic Targeting of Aldolase A Interactions Inhibits Lung Cancer Metastasis and Prolongs Survival.
2019 Jul J Acquir Immune Defic Syndr Antiretroviral Adherence Level Necessary for HIV Viral Suppression using Real-World Data.
2019 Jul Clin Exp Nephrol Prevalence of chronic kidney disease among HIV-1-infected patients receiving a combination antiretroviral therapy.
2019 Jul Curr Med Res Opin Incidence of select chronic co-morbidities among a population-based cohort of HIV-positive individuals receiving highly active antiretroviral therapy.
2019 Jul Intervirology HIV-1 Drug Resistance Mutations among Antiretroviral Drug-Experienced Patients in the South of Iran.
2019 Jul Intervirology HIV-1 Integrase Resistance among Highly Antiretroviral Experienced Patients from Morocco.
2019 Jul J Med Virol Homeostatic model assessment for insulin resistance index trajectories in HIV-infected patients treated with different first-line antiretroviral regimens.
2019 Jul J Neurovirol Hepatitis C virus-related factors associated WITH cognitive performance in HIV-HCV-coinfected patients.
2019 Jul J Antimicrob Chemother A systematic review of the genetic mechanisms of dolutegravir resistance.
2019 Jul J Antimicrob Chemother Dual therapy combining raltegravir with etravirine maintains a high level of viral pression over 96 weeks in long-term experienced HIV-infected individuals over 45 years on a PI-based regimen: results from the Phase II ANRS 163 ETRAL study.
2019 Medicine (Baltimore) Risk of elevation of serum creatine kinase among HIV-positive individuals receiving dolutegravir-based combination antiretroviral therapy.
2019 Infect Dis Clin North Am Initial Antiretroviral Therapy in an Integrase Inhibitor Era: Can We Do Better?
2019 Infect Dis (Lond) Improvement in liver steatosis after the switch from a ritonavir-boosted protease inhibitor to raltegravir in HIV-infected patients with non-alcoholic fatty liver disease.
2019 Lancet HIV Correlates of HIV RNA concentrations in cerebrospinal fluid during antiretroviral therapy: a longitudinal cohort study.
2019 Jul J Acquir Immune Defic Syndr Impact of Integrase Inhibition Compared With Nonnucleoside Inhibition on HIV Reservoirs in Lymphoid Tissues.
2019 J Pharmacol Exp Ther Mechanistic Basis of Cabotegravir-Glucuronide Disposition in Humans.
2019 AIDS Res Hum Retroviruses Trends in HIV-1 Drug Resistance Mutations from a U.S. Reference Laboratory from 2006 to 2017.
2019 Drug Metab Dispos Clinical Extrapolation of the Effects of Dolutegravir and Other HIV Integrase Inhibitors on Folate Transport Pathways.
2019 May BMC Infect Dis Comparative efficacy and safety of dolutegravir relative to common core agents in treatment-naïve patients infected with HIV-1: a systematic review and network meta-analysis.
2019 J Pharm Pharmacol Antiretroviral agents in pre-exposure prophylaxis: emerging and advanced trends in HIV prevention.
2019 Jul J Control Release 2-Hydroxypropyl-β-cyclodextrin-enhanced pharmacokinetics of cabotegravir from a nanofluidic implant for HIV pre-exposure prophylaxis.
2019 Drugs Today (Barc) Dolutegravir plus lamivudine dual therapy - a new option for initial antiretroviral therapy.
2019 Antimicrob Agents Chemother Interpretation of Drug Interactions between Dolutegravir and Artemether-Lumefantrine or Artesunate-Amodiaquine.
2019 May Clin Infect Dis Cabotegravir is Not Associated with Weight Gain in HIV-uninfected Individuals in HPTN 077.
2019 Open Forum Infect Dis INSTI-Based Triple Regimens in Treatment-Naïve HIV-Infected Patients Are Associated With HIV-RNA Viral Load Suppression at Ultralow Levels.
2019 May Clin Infect Dis Greater Weight Gain in Treatment Naïve Persons Starting Dolutegravir-Based Antiretroviral Therapy.
2019 Aug AIDS E157Q integrase strand-transfer inhibitor stitution in patients with acuterecent HIV infection.
2019 Expert Opin Pharmacother Pharmacotherapeutic management of HIV in transplant patients.
2019 Int J STD AIDS Safety and efficacy of dolutegravir in hemodialysis.
2019 Lancet HIV Bictegravir combined with emtricitabine and tenofovir alafenamide versus dolutegravir, abacavir, and lamivudine for initial treatment of HIV-1 infection: week 96 results from a randomised, double-blind, multicentre, phase 3, non-inferiority trial.
2019 Aug J Acquir Immune Defic Syndr Immunological and Neurometabolite Changes Associated With Switch From Efavirenz to an Integrase Inhibitor.
2019 May Nat Commun Drug resistance emergence in macaques administered cabotegravir long-acting for pre-exposure prophylaxis during acute SHIV infection.
2019 Int J STD AIDS Assessment of antiretroviral third agent virologic durability after initiation of first antiretroviral regimen.
2019 Apr Antivir Ther Lean mass declines consistently over 10 years in people living with HIV on antiretroviral therapy, with patterns differing by sex.
2019 Acta Naturae Consensus Integrase of a New HIV-1 Genetic Variant CRF63_02A1.
2019 Aug J Acquir Immune Defic Syndr Is There a Safety Signal for Dolutegravir and Integrase Inhibitors During Pregnancy?
2019 Ther Adv Infect Dis Optimal treatment of HIV-associated neurocognitive disorders: myths and reality. A critical review.
2019 Int J STD AIDS Efficacy and safety of abacavirlamivudine with raltegravir in treatment-experienced and treatment-naïve patients with HIV-1 infection: an observational, retrospective, multi-centre study.
2019 Apr ACS Med Chem Lett Synthesis and Anti-HIV Profile of a Novel Tetrahydroindazolylbenzamide Derivative Obtained by Oxazolone Chemistry.
2019 Antiviral Res A potential long-acting bictegravir loaded nano-drug delivery system for HIV-1 infection: A proof-of-concept study.
2019 J Infect Chemother A model-based comparative meta-analysis of the efficacy of dolutegravir-based and efavirenz-based regimens in HIV-infected patients.
2019 Clin Drug Investig Paediatric Integrase Inhibitor Use in a Real-Life Setting: A Single-Centre Cohort Experience 2009-2018.
2019 Apr Proc Natl Acad Sci U S A Mutations in the HIV-1 envelope glycoprotein can broadly rescue blocks at multiple steps in the virus replication cycle.
2019 Int J STD AIDS Ritonavir- or cobicistat-boosted antiretroviral therapy and direct oral anticoagulants: A case for apixaban.
2018 Oct Clinical Review Report: B...
2018 Oct Pharmacoeconomic Review R...
2019 Jul AIDS Virological response to integrase strand transfer inhibitor-based antiretroviral combinations in HIV-1 group O-infected patients.
2019 Mar Pharm Res Antiretroviral Hydrophobic Core Graft-Copolymer Nanoparticles: The Effectiveness against Mutant HIV-1 Strains and in Vivo Distribution after Topical Application.
2019 Jul J Acquir Immune Defic Syndr Evaluation of Neural Tube Defects (NTDs) After Exposure to Raltegravir During Pregnancy.
2019 Int J Antimicrob Agents Effectiveness of switching from protease inhibitors to dolutegravir in combination with nucleoside reverse transcriptase inhibitors as maintenance antiretroviral therapy among HIV-positive patients.
2019 AIDS Rev Neuropsychiatric Adverse Events with Dolutegravir and Other Integrase Strand Transfer Inhibitors
2019 Mar Antivir Ther Effect of rifabutin on the pharmacokinetics of oral cabotegravir in healthy jects.
2019 Open Forum Infect Dis Prevalence of Human Immunodeficiency Virus-1 Integrase Strand Transfer Inhibitor Resistance in British Columbia, Canada Between 2009 and 2016: A Longitudinal Analysis.
2019 Antivir Ther Tenofovir and emtricitabine resistance among antiretroviral-naive patients in the Canadian Observational Cohort Collaboration: implications for PrEP.
2019 Mar Mini Rev Med Chem Recent Advances towards Treatment of HIV: Synthesis and SAR Studies.
2019 PLoS One Role of pretreatment variables on plasma HIV RNA value at the sixth month of antiretroviral therapy including all first line drugs in HIV naïve patients: A path analysis approach.
2019 Evid Based Complement Alt... Flavonol 7-iOi-Glucoside Herbacitrin Inhibits HIV-1 Replication through Simultaneous Integrase and Reverse Transcriptase Inhibition.
2019 Clin Pharmacol Drug Dev A Phase 1 Study to Evaluate the Pharmacokinetics and Safety of Cabotegravir in Patients With Hepatic Impairment and Healthy Matched Controls.
2019 Clin Pharmacol Drug Dev A Phase I Study to Evaluate the Pharmacokinetics and Safety of Cabotegravir in Adults With Severe Renal Impairment and Healthy Matched Control Participants.
2019 Drug Metab Dispos Mechanistic Assessment of Extrahepatic Contributions to Glucuronidation of Integrase Strand Transfer Inhibitors.
2019 Antimicrob Agents Chemother Comparison of the Antiviral Activity of Bictegravir against HIV-1 and HIV-2 Isolates and Integrase Inhibitor-Resistant HIV-2 Mutants.
2019 Antimicrob Agents Chemother Resistance Analysis of Bictegravir-Emtricitabine-Tenofovir Alafenamide in HIV-1 Treatment-Naive Patients through 48 Weeks.
2019 Jan J Virus Erad Immunological profile of an infant treated with integrase inhibitor from the neonatal period.
2019 J Int Assoc Provid AIDS Care Maintenance of Viral Suppression after Optimization Therapy from Etravirine Plus Raltegravir to Rilpivirine Plus Dolutegravir in HIV-1-Infected Patients.
2019 Virus Genes Integrase strand transfer inhibitor-based regimen is related with a limited HIV-1 V3 loop evolution in clinical practice.
2019 AIDS Res Hum Retroviruses Absence of Integrase Strand Transfer Inhibitor Associated Resistance in Antiretroviral Therapy Naïve and Experienced Individuals from Western India.
2019 Feb J Antimicrob Chemother Resistance to integrase inhibitors: a national study in HIV-1-infected treatment-naive and -experienced patients.
2019 Internist (Berl) [Modern HIV treatment].
2019 Feb Clin Transplant Solid organ transplantation in the HIV-infected patient: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice.
2019 Feb Retrovirology Replication competence of virions induced from CD4+ lymphocytes latently infected with HIV.