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Recent literature: D2 receptor antagonist
Date Journal Article title
2020 Nature Dopamine D2 receptors in discrimination learning and spine enlargement.
2020 Mar Neurotox Res The Effect of Orexin Receptor Antagonism on Quinpirole-Induced Compulsive-Like Checking Behavior in Rats.
2020 Mar Neuroimage Separating dopamine D2 and D3 receptor sources of [11C]-(+)-PHNO binding potential: Independent component analysis of competitive binding.
2020 Mar Physiol Behav Adenosine A1 receptor agonist induces visceral antinociception via 5-HT1A, 5-HT2A, dopamine D1 or cannabinoid CB1 receptors, and the opioid system in the central nervous system.
2020 Mar Science Dopamine promotes cognitive effort by biasing the benefits versus costs of cognitive work.
2020 Mar Korean J Intern Med Blockade of thymic stromal lymphopoietin and CRTH2 attenuates airway inflammation in a murine model of allergic asthma.
2020 Mar Eur J Med Chem Discovery of aryl-piperidine derivatives as potential antipsychotic agents using molecular hybridization strategy.
2020 Behav Neurosci Dissociating the effects of dopamine D2 receptors on effort-based versus value-based decision making using a novel behavioral approach.
2020 Mar Neuropsychopharmacol Rep Time estimation in a case of Tourette's syndrome: Effect of antipsychotic medications.
2020 Mar Neuropharmacology NQO1 regulates pharmaco-behavioral effects of d-amphetamine in striatal dopaminergic system in mice.
2020 Pharmacol Rep Antidepressant-like effects of kynurenic acid in a modified forced swim test.
2020 Mar Br J Pharmacol Source of dopamine in gastric juice and luminal dopamine-induced duodenal bicarbonate secretion via apical dopamine receptor 2.
2020 Mar J Allergy Clin Immunol Pract The Utility of Measuring Urinary Metabolites of Mast Cell Mediators in Systemic Mastocytosis and Mast Cell Activation Syndrome.
2020 May Brain Res Role of hippocampal dopamine receptors in the antinociceptive responses induced by chemical stimulation of the lateral hypothalamus in animal model of acute pain.
2020 Mar Naunyn Schmiedebergs Arch... 5-HT2A receptors but not cannabinoid receptors in the central nervous system mediate levodopa-induced visceral antinociception in conscious rats.
2020 Feb Eur J Pharmacol Potential synergistic effects of novel hematopoietic prostaglandin D synthase inhibitor TAS-205 and different types of anti-allergic medicine on nasal obstruction in a Guinea pig model of experimental allergic rhinitis.
2020 Mar ACS Chem Neurosci Photoactivatable Dopamine and Sulpiride to Explore the Function of Dopaminergic Neurons and Circuits.
2020 Feb J Appl Toxicol Wastewater-derived antagonistic activities of G protein-coupled receptor-acting pharmaceuticals in river water.
2020 Feb Neurogastroenterol Motil Losartan improves visceral sensation and gut barrier in a rat model of irritable bowel syndrome.
2020 Behav Pharmacol D1- but not D2-like dopamine receptor antagonist in the CA1 region of the hippocampus reduced stress-induced reinstatement in extinguished morphine-conditioning place preference in the food-deprived rats.
2020 Jan Eur Neuropsychopharmacol Role of toll-like receptor 4 antagonist Lipopolysaccharide-Rhodobacter sphaeroides on acute stress-induced voluntary ethanol preference and drinking behaviour: In vivo Swiss Albino mouse model.
2020 Mar Mol Pharm Effect of Dopamine D2 Receptor Antagonists on [18F]-FEOBV Binding.
2019 Adv Biomed Res An Assessment between D1 Receptor Agonist and D2 receptor Antagonist into the Ventral Tegmental Area on Conditioned Place Preference and Locomotor Activity.
2020 Jan Invest Ophthalmol Vis Sci Topical Pergolide Enhance Corneal Nerve Regrowth Following Induced Corneal Abrasion.
2020 Eur Neuropsychopharmacol The adverse effects of pramipexole on probability discounting are not reversed by acute D2 or D3 receptor antagonism.
2020 Jan BMC Biol Control of glutamate release by complexes of adenosine and cannabinoid receptors.
2020 Jan Sci Rep Structure-based development of caged dopamine D2D3 receptor antagonists.
2020 Arch Soc Esp Oftalmol Dopamine D2 receptor influences eye development and function in Zebrafish.
2020 Expert Opin Pharmacother The pharmacological management of asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS).
2020 Mar Drug Alcohol Depend Role of the treatment environment in the effects of aripiprazole on ethanol-induced behavioral sensitization and conditioned place preference in female mice.
2020 Feb J Exp Biol Experimental evidence for a role of dopamine in avian personality traits.
2020 Jan Brain Sci Pharmacological Mechanisms Involved in Sensory Gating Disruption Induced by (±)-3,4-Methylene- Dioxymethamphetamine (MDMA): Relevance to Schizophrenia.
2020 Neuropsychopharmacology Dorsal and ventral striatal dopamine D1 and D2 receptors differentially modulate distinct phases of serial visual reversal learning.
2020 Feb Environ Sci Technol Biological Activity-Based Prioritization of Pharmaceuticals in Wastewater for Environmental Monitoring: G Protein-Coupled Receptor Inhibitors.
2020 Neurobiol Learn Mem The D2-family receptor agonist bromocriptine but, not nicotine, reverses NMDA receptor antagonist-induced working memory deficits in the radial arm maze in mice.
2020 Jan Stem Cell Res Ther Dopamine D1 receptor-mediated activation of the ERK signaling pathway is involved in the osteogenic differentiation of bone mesenchymal stem cells.
2020 Apr Biol Psychiatry Deletion of Glycogen Synthase Kinase-3β in D2 Receptor-Positive Neurons Ameliorates Cognitive Impairment via NMDA Receptor-Dependent Synaptic Plasticity.
2020 Feb Neuroscience Dopamine Evokes a Trace Amine Receptor-dependent Inward Current that is Regulated by AMP Kinase in Substantia Nigra Dopamine Neurons.
2019 Dec Hum Brain Mapp Amisulpride and l-DOPA modulate cortical brain nuclei connectivity in resting-state pharmacologic magnetic resonance imaging.
2019 Dec Neurosci Res Dopamine D1 and muscarinic acetylcholine receptors in dorsal striatum are required for high speed running.
2020 J Pharmacol Sci Involvement of the dopamine D1 receptor system in the anxiolytic effect of cedrol in the elevated plus maze and light-dark box tests.
2020 Psychopharmacology (Berl) Binding of the D3-preferring antipsychotic candidate F17464 to dopamine D3 and D2 receptors: a PET study in healthy jects with [11C]-(+)-PHNO.
2020 Mar J Ethnopharmacol Anxiolytic- and antidepressant-like activities of hydroethanol leaf extract of Newbouldia laevis (P.Beauv.) Seem. (Bignoniaceae) in mice.
2019 Ther Adv Psychopharmacol Cannabidiol as a potential treatment for psychosis.
2019 Nihon Yakurigaku Zasshi [Preclinical pharmacological profiles and clinical efficacy of the novel antipsychotic drug brexpiprazole (REXULTI® Tablets 1 mg, 2 mg)].
2019 Nov Sci Rep Sucrose intake lowers μ-opioid and dopamine D23 receptor availability in porcine brain.
2020 Br J Pharmacol The novel antipsychotic cariprazine stabilizes gamma oscillations in rat hippocampal slices.
2019 Nov J Neurosci Res Blockade of dopamine D1 receptors in male rats disrupts morphine reward in pain naïve but not in chronic pain states.
2020 Feb Behav Brain Res Haloperidol-induced hypokinesia in rats is differentially affected by the lightdark phase, age, and melatonin.
2019 Nov Arch Biochem Biophys 15-Deoxy-Δ12,14-prostaglandin J2 ameliorates dextran sulfate sodium-induced colitis in mice through heme oxygenase-1 induction.
2020 Jan Neuro Oncol Biological activity of weekly ONC201 in adult recurrent glioblastoma patients.
2019 Nov Sci Rep Differential effects of D-cycloserine and amantadine on motor behavior and D23 receptor binding in the nigrostriatal and mesolimbic system of the adult rat.
2020 Feb Int J Neuropsychopharmacol Balanced Activation of Striatal Output Pathways by Faster Off-Rate PDE10A Inhibitors Elicits Not Only Antipsychotic-Like Effects But Also Procognitive Effects in Rodents.
2019 J Clin Psychopharmacol Dopamine D2 Receptor Occupancy Estimated From Plasma Concentrations of Four Different Antipsychotics and the Subjective Experience of Physical and Mental Well-Being in Schizophrenia: Results From the Randomized NeSSy Trial.
2019 JBMR Plus Impaired Gastric Hormone Regulation of Osteoblasts and Lysyl Oxidase Drives Bone Disease in Diabetes Mellitus.
2019 Nov Pharmacol Res New treatments for asthma: From the pathogenic role of prostaglandin D2 to the therapeutic effects of fevipiprant.
2020 Clin Exp Allergy A phase 2 study to evaluate the safety, efficacy and pharmacokinetics of DP2 antagonist GB001 and to explore biomarkers of airway inflammation in mild-to-moderate asthma.
2019 Aug EJNMMI Radiopharm Chem Improved synthesis of [18F] fallypride and characterization of a Huntington's disease mouse model, zQ175DN KI, using longitudinal PET imaging of D2D3 receptors.
2020 Jan Neuropharmacology Neuromedin U induces self-grooming in socially-stimulated mice.
2019 J Cell Mol Med Effect and mechanisms of sacral nerve stimulation on visceral hypersensitivity mediated by nerve growth factor.
2020 Comp Biochem Physiol A Mo... Daily variation of D2 dopamine receptor transcription in the brain of the Japanese eel Anguilla japonica and its regulation with dopamine and melatonin.
2019 PLoS One Dopamine receptor antagonists effects on low-dimensional attractors of local field potentials in optogenetic mice.
2019 Exp Physiol The effect of dopamine on pulmonary diffusing capacity and capillary blood volume responses to exercise in young healthy humans.
2019 Nov J Med Chem Structure-Kinetic Profiling of Haloperidol Analogues at the Human Dopamine D2 Receptor.
2019 J Pharmacol Exp Ther Newly Developed Dopamine D3 Receptor Antagonists, iRi-VK4-40 and iRi-VK4-116, Do Not Potentiate Cardiovascular Effects of Cocaine or Oxycodone in Rats.
2019 Oct Stress Involvement of D2 receptor in the NAc in chronic unpredictable stress-induced depression-like behaviors.
2019 Nov Bioorg Med Chem Lett Design, synthesis and biological evaluation of novel serotonin and dopamine receptor ligands being 6-bromohexyl saccharine derivatives.
2019 Sep Int J Mol Sci Risperidone Treatment after Transient Ischemia Induces Hypothermia and Provides Neuroprotection in the Gerbil Hippocampus by Decreasing Oxidative Stress.
2019 Nov Biochem Biophys Res Commun Dopaminergic mechanisms in the lateral hypothalamus regulate feeding behavior in association with neuropeptides.
2019 J Pharmacol Exp Ther The Role of Dopamine D3 Receptor Partial Agonism in Cariprazine-Induced Neurotransmitter Efflux in Rat Hippocampus and Nucleus Accumbens.
2019 CNS Spectr Keeping up with the therapeutic advances in schizophrenia: a review of novel and emerging pharmacological entities.
2019 Nov Neuroimage Validity and reliability of extrastriatal [11C]raclopride binding quantification in the living human brain.
2019 Oct Am J Physiol Gastrointest... Roles of the noradrenergic nucleus locus coeruleus and dopaminergic nucleus A11 region as raspinal defecation centers in rats.
2019 J Neurooncol Pediatric and adult H3 K27M-mutant diffuse midline glioma treated with the selective DRD2 antagonist ONC201.
2019 Behav Neurosci Involvement of D1- and D2-like dopamine receptors within the rat nucleus accumbens in the maintenance of morphine rewarding properties in the rats.