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Recent literature: 5-HT2 receptor agonist
Date Journal Article title
2019 Aug Eur J Med Chem Design of fluorinated cyclopropane derivatives of 2-phenylcyclopropylmethylamine leading to identification of a selective serotonin 2C (5-HT2C) receptor agonist without 5-HT2B agonism.
2019 Korean J Physiol Pharmacol Potentiation of the glycine response by serotonin on the stantia gelatinosa neurons of the trigeminal nucleus caudalis in mice.
2019 Expert Rev Clin Pharmacol Changing the treatment paradigm for Parkinson's disease psychosis with pimavanserin.
2019 Bioelectromagnetics Effects of 5-HT1 and 5-HT 2 Receptor Agonists on Electromagnetic Field-Induced Analgesia in Rats.
2019 Jul Eur J Pharmacol Monoamine receptor interaction profiles of 4-aryl-stituted 2,5-dimethoxyphenethylamines (2C-BI derivatives).
2019 Oxid Med Cell Longev Enhancement by Hydrogen Peroxide of Calcium Signals in Endothelial Cells Induced by 5-HT1B and 5-HT2B Receptor Agonists.
2019 Feb Int J Mol Sci Glucagon-Like Peptide-1 (GLP-1) and 5-Hydroxytryptamine 2c (5-HT2c) Receptor Agonists in the Ventral Tegmental Area (VTA) Inhibit Ghrelin-Stimulated Appetitive Reward.
2019 Neurobiol Dis Synergistic action of CB1 and 5-HT2B receptors in preventing pilocarpine-induced status epilepticus in rats.
2019 Apr Biol Pharm Bull Effect of Selective Serotonin (5-HT)2B Receptor Agonist BW723C86 on Epidermal Growth FactorTransforming Growth Factor-α Receptor Tyrosine Kinase and Ribosomal p70 S6 Kinase Activities in Primary Cultures of Adult Rat Hepatocytes.
2019 Hypertens Res Hypertension exhibits 5-HT4 receptor as a modulator of sympathetic neurotransmission in the rat mesenteric vasculature.
2019 Exp Clin Psychopharmacol Effects of acute and repeated treatment with serotonin 5-HT2A receptor agonist hallucinogens on intracranial self-stimulation in rats.
2019 JAAPA Can pimavanserin help patients with Parkinson disease psychosis?
2019 Int J Neurosci The effect of serotonin on penicillin-induced epileptiform activity.
2019 Drug Metab Dispos Serotonin Receptors of 5-HT2 Type in the Hypothalamic Arcuate Nuclei Positively Regulate Liver Cytochrome P450 via Stimulation of the Growth Hormone-Releasing HormoneGrowth Hormone Hormonal Pathway.
2019 Jan Drug Alcohol Depend Effects of acute treatments with the serotonin 2A antagonist M100907 alone or in combination with the serotonin 2C agonist WAY163909 on methamphetamine self-administration in rhesus monkeys.
2019 Can J Physiol Pharmacol Fluoxetine oral treatment discloses 5-HT1D receptor as vagoinhibitor of the cardiac cholinergic neurotransmission in rat.
2019 Exp Physiol Evidence for protein kinase involvement in the 5-HT-[Ca2+ ]i -pannexin-1 signalling pathway in type II glial cells of the rat carotid body.
2019 Psychopharmacology (Berl) Chronic treatment with a metabotropic mGlu23 receptor agonist diminishes behavioral response to a phenethylamine hallucinogen.
2019 Toxicol In Vitro MDMA modulates 5-HT1-mediated contractile response of the human internal thoracic artery in vitro.
2019 Jan Eur J Pharmacol The serotonin 2C receptor agonist WAY-163909 attenuates ketamine-induced hypothermia in mice.
2018 Oct Elife Changes in global and thalamic brain connectivity in LSD-induced altered states of consciousness are attributable to the 5-HT2A receptor.
2018 Clin Neuropharmacol Nighttime Sleep and Daytime Sleepiness Improved With Pimavanserin During Treatment of Parkinson's Disease Psychosis.
2019 Psychopharmacology (Berl) Pharmacological characterization of the LSD analog N-ethyl-N-cyclopropyl lysergamide (ECPLA).
2018 Psychopharmacology (Berl) The neuropharmacology of sleep paralysis hallucinations: serotonin 2A activation and a novel therapeutic drug.
2018 Nov Neurosci Lett Effect of 5-HT2A receptor antagonist ketanserin on micturition in male rats.
2019 Chem Biol Drug Des In vitro functional evaluation of isolaureline, dicentrine and glaucine enantiomers at 5-HT2 and α1 receptors.
2018 Neuropharmacology Reduced cortical serotonin 5-HT2A receptor binding and glutamate activity in high compulsive drinker rats.
2019 Handb Exp Pharmacol Other Antidepressants.
2018 Sep Neuropharmacology Interplay between 5-HT2C and 5-HT1A receptors in the dorsal periaqueductal gray in the modulation of fear-induced antinociception in mice.
2018 Neurol Sci Pimavanserin use in a movement disorders clinic: a single-center experience.
2018 Clin Neuropharmacol Pimavanserin for Psychotic Symptoms in People With Parkinsonism: A Second Chart Review.
2018 Pharmacol Biochem Behav Blockade of serotonin 5-HT2A receptors potentiates dopamine D2 activation-induced disruption of pup retrieval on an elevated plus maze, but has no effect on D2 blockade-induced one.
2018 JAAPA Flibanserin for hypoactive sexual desire disorder in premenopausal women.
2018 Am Heart J Design and rationale for the Cardiovascular and Metabolic Effects of Lorcaserin in Overweight and Obese Patients-Thrombolysis in Myocardial Infarction 61 (CAMELLIA-TIMI 61) trial.
2018 Psychopharmacology (Berl) Selective effects of 5-HT2C receptor modulation on performance of a novel valence-probe visual discrimination task and probabilistic reversal learning in mice.
2018 Drug Metab Dispos Activation of 5-HT1A Receptors in the Hypothalamic Paraventricular Nuclei Negatively Regulates Cytochrome P450 Expression and Activity in Rat Liver.
2018 Jul Behav Brain Res 5-HT2C receptors in the ventral tegmental area, but not in the arcuate nucleus, mediate the hypophagic and hypolocomotor effects of the selective 5-HT2C receptor agonist AR231630 in rats.
2018 Neuropharmacology Activation of 5-HT2C (but not 5-HT1A) receptors in the amygdala enhances fear-induced antinociception: Blockade with local 5-HT2C antagonist or systemic fluoxetine.
2018 Brain Behav 5-HT2CR antagonist5-HT2CR inverse agonist recovered the increased isolation-induced aggressive behavior of BALBc mice mediated by ADAR1 (p110) expression and Htr2c RNA editing.
2018 Neuropsychopharmacology Positive regulation of raphe serotonin neurons by serotonin 2B receptors.
2018 Jul Am J Physiol Renal Physiol Role of the serotonergic system in urethral continence reflexes during sneezing in rats.
2018 Feb Cell 5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology.
2018 May Am J Physiol Regul Integr... Cross-talk inhibition between 5-HT2B and 5-HT7 receptors in phrenic motor facilitation via NADPH oxidase and PKA.
2018 Jan Curr Psychiatry Rep Treating Hallucinations and Delusions Associated With Parkinson's Disease Psychosis.
2018 May Behav Brain Res Assessment of impulsivity in adolescent mice: A new training procedure for a 3-choice serial reaction time task.
2018 J Comp Physiol A Neuroeth... Presynaptic serotonin 5-HT1BD receptor-mediated inhibition of glycinergic transmission to the frog spinal motoneurons.
2017 Dec Toxins (Basel) Peripheral 5-HT3 Receptors Are Involved in the Antinociceptive Effect of Bunodosine 391.
2018 Pharmacol Biochem Behav The antipsychotic trifluoperazine reduces marble-burying behavior in mice via D2 and 5-HT2A receptors: Implications for obsessive-compulsive disorder.
2018 J Pharmacol Exp Ther Inhibition of Cocaine and 3,4-Methylenedioxypyrovalerone (MDPV) Self-Administration by Lorcaserin Is Mediated by 5-HT2C Receptors in Rats.
2017 Dec Nat Commun The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand.
2017 J Sex Med Understanding the Role of Serotonin in Female Hypoactive Sexual Desire Disorder and Treatment Options.
2018 Clin Ther Effects of Flibanserin on the Pharmacokinetics of a Combined EthinylestradiolLevonorgestrel Oral Contraceptive in Healthy Premenopausal Women: A Randomized Crossover Study.
2018 Mar Neuropharmacology Peripheral 5-HT3 mediates mirror-image pain by a cross-talk with acid-sensing ion channel 3.
2017 Curr Pharm Biotechnol Retrospective Demonstration of 25I-NBOMe Acute Poisoning Using Hair Analysis.
2017 PLoS One Regulatory mechanism of CCN2 production by serotonin (5-HT) via 5-HT2A and 5-HT2B receptors in chondrocytes.
2017 Dec J Med Chem A Positive Allosteric Modulator of the Serotonin 5-HT2C Receptor for Obesity.
2017 Dec Eur J Med Chem Synthesis and biological evaluation of new naphtho- and quinolinocyclopentane derivatives as potent melatoninergic (MT1MT2) and serotoninergic (5-HT2C) dual ligands.
2018 Psychopharmacology (Berl) The 5-HT2C receptor agonist meta-chlorophenylpiperazine (mCPP) reduces palatable food consumption and BOLD fMRI responses to food images in healthy female volunteers.
2017 J Psychopharmacol Role of impulsivity and reward in the anti-obesity actions of 5-HT2C receptor agonists.
2017 Dec Drug Alcohol Depend Effects of lorcaserin (Belviq®) on nicotine- and food-maintained responding in non-human primates.
2018 Neuropharmacology Activation of 5-HT2A receptor disrupts rat maternal behavior.
2017 Neuropharmacology Serotonin gating of cortical and thalamic glutamate inputs onto principal neurons of the basolateral amygdala.
2017 J Labelled Comp Radiopharm Synthesis, radiofluorination, and preliminary evaluation of the potential 5-HT2A receptor agonists [18 F]Cimbi-92 and [18 F]Cimbi-150.
2017 Adv Exp Med Biol Role of 5-HT2 and 5-HT7 Serotonin Receptors, and Protein Kinases C and A on Taurine Transport in Lymphocytes of Rats Treated with Fluoxetine.
2017 Expert Rev Clin Pharmacol Pimavanserin, a novel antipsychotic for management of Parkinson's disease psychosis.
2017 J Womens Health (Larchmt) Effect of Flibanserin Treatment on Body Weight in Premenopausal and Postmenopausal Women with Hypoactive Sexual Desire Disorder: A Post Hoc Analysis.
2017 Clin Exp Pharmacol Physiol 5-HT modulates the rat mesenteric vasopressor outflow by 5-HT1D sympatholytic receptors.
2017 Br J Pharmacol Ameliorative effect of chlorpromazine hydrochloride on visceral hypersensitivity in rats: possible involvement of 5-HT2A receptor.
2017 Psychopharmacology (Berl) Pharmacological evidence that 5-HT2C receptor blockade selectively improves decision making when rewards are paired with audiovisual cues in a rat gambling task.
2018 BJU Int Chronic spinal cord injury causes upregulation of serotonin (5-HT)2A and 5-HT2C receptors in lumbosacral cord motoneurons.
2018 Curr Top Behav Neurosci Hallucinogens and Serotonin 5-HT2A Receptor-Mediated Signaling Pathways.
2017 Sex Med Rev Flibanserin Efficacy and Safety in Premenopausal Women With Generalized Acquired Hypoactive Sexual Desire Disorder.
2017 Jul J Med Chem Discovery of N-Substituted (2-Phenylcyclopropyl)methylamines as Functionally Selective Serotonin 2C Receptor Agonists for Potential Use as Antipsychotic Medications.
2017 J Pharmacol Sci Serotonergic modulation of nicotine-induced kinetic tremor in mice.
2017 Sep Drug Alcohol Depend Synthetic cathinones and stereochemistry: S enantiomer of mephedrone reduces anxiety- and depressant-like effects in cocaine- or MDPV-abstinent rats.