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2019 Feb |
Neurobiol Dis |
Synergistic action of CB1 and 5-HT2B receptors in preventing pilocarpine-induced status epilepticus in rats. |
|
2019 Jan |
Hypertens Res |
Hypertension exhibits 5-HT4 receptor as a modulator of sympathetic neurotransmission in the rat mesenteric vasculature. |
|
2018 Dec |
Int J Neurosci |
The Effect of Serotonin on Penicillin-induced Epileptiform Activity. |
|
2019 |
Drug Metab Dispos |
Serotonin Receptors of 5-HT2 Type in the Hypothalamic Arcuate Nuclei Positively Regulate Liver Cytochrome P450 via Stimulation of the Growth Hormone-Releasing HormoneGrowth Hormone Hormonal Pathway. |
|
2019 |
Can J Physiol Pharmacol |
Fluoxetine oral treatment discloses 5-HT1D receptor as vagoinhibitor of the cardiac cholinergic neurotransmission in rat. |
|
2019 |
Exp Physiol |
Evidence for protein kinase involvement in the 5-HT-[Ca2+ ]i -pannexin-1 signalling pathway in type II glial cells of the rat carotid body. |
|
2019 |
Toxicol In Vitro |
MDMA modulates 5-HT1-mediated contractile response of the human internal thoracic artery in vitro. |
|
2019 Jan |
Eur J Pharmacol |
The serotonin 2C receptor agonist WAY-163909 attenuates ketamine-induced hypothermia in mice. |
|
2018 Oct |
Elife |
Changes in global and thalamic brain connectivity in LSD-induced altered states of consciousness are attributable to the 5-HT2A receptor. |
|
2018 |
Clin Neuropharmacol |
Nighttime Sleep and Daytime Sleepiness Improved With Pimavanserin During Treatment of Parkinson's Disease Psychosis. |
|
2018 Oct |
Psychopharmacology (Berl) |
Pharmacological characterization of the LSD analog N-ethyl-N-cyclopropyl lysergamide (ECPLA). |
|
2018 |
Psychopharmacology (Berl) |
The neuropharmacology of sleep paralysis hallucinations: serotonin 2A activation and a novel therapeutic drug. |
|
2018 Nov |
Neurosci Lett |
Effect of 5-HT2A receptor antagonist ketanserin on micturition in male rats. |
|
2019 |
Chem Biol Drug Des |
In vitro functional evaluation of isolaureline, dicentrine and glaucine enantiomers at 5-HT2 and α1 receptors. |
|
2018 Sep |
Handb Exp Pharmacol |
Other Antidepressants. |
|
2018 |
Neurol Sci |
Pimavanserin use in a movement disorders clinic: a single-center experience. |
|
2018 |
Clin Neuropharmacol |
Pimavanserin for Psychotic Symptoms in People With Parkinsonism: A Second Chart Review. |
|
2018 |
JAAPA |
Flibanserin for hypoactive sexual desire disorder in premenopausal women. |
|
2018 |
Drug Metab Dispos |
Activation of 5-HT1A Receptors in the Hypothalamic Paraventricular Nuclei Negatively Regulates Cytochrome P450 Expression and Activity in Rat Liver. |
|
2018 Jul |
Behav Brain Res |
5-HT2C receptors in the ventral tegmental area, but not in the arcuate nucleus, mediate the hypophagic and hypolocomotor effects of the selective 5-HT2C receptor agonist AR231630 in rats. |
|
2018 |
Neuropsychopharmacology |
Positive regulation of raphe serotonin neurons by serotonin 2B receptors. |
|
2018 Feb |
Cell |
5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology. |
|
2018 May |
Am J Physiol Regul Integr... |
Cross-talk inhibition between 5-HT2B and 5-HT7 receptors in phrenic motor facilitation via NADPH oxidase and PKA. |
|
2018 May |
Behav Brain Res |
Assessment of impulsivity in adolescent mice: A new training procedure for a 3-choice serial reaction time task. |
|
2018 |
J Comp Physiol A Neuroeth... |
Presynaptic serotonin 5-HT1BD receptor-mediated inhibition of glycinergic transmission to the frog spinal motoneurons. |
|
2017 Dec |
Toxins (Basel) |
Peripheral 5-HT3 Receptors Are Involved in the Antinociceptive Effect of Bunodosine 391. |
|
2018 |
Pharmacol Biochem Behav |
The antipsychotic trifluoperazine reduces marble-burying behavior in mice via D2 and 5-HT2A receptors: Implications for obsessive-compulsive disorder. |
|
2017 Dec |
Nat Commun |
The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand. |
|
2017 |
J Sex Med |
Understanding the Role of Serotonin in Female Hypoactive Sexual Desire Disorder and Treatment Options. |
|
2018 |
Clin Ther |
Effects of Flibanserin on the Pharmacokinetics of a Combined EthinylestradiolLevonorgestrel Oral Contraceptive in Healthy Premenopausal Women: A Randomized Crossover Study. |
|
2018 Mar |
Neuropharmacology |
Peripheral 5-HT3 mediates mirror-image pain by a cross-talk with acid-sensing ion channel 3. |
|
2017 |
Curr Pharm Biotechnol |
Retrospective Demonstration of 25I-NBOMe Acute Poisoning Using Hair Analysis. |
|
2017 |
PLoS One |
Regulatory mechanism of CCN2 production by serotonin (5-HT) via 5-HT2A and 5-HT2B receptors in chondrocytes. |
|
2017 Dec |
J Med Chem |
A Positive Allosteric Modulator of the Serotonin 5-HT2C Receptor for Obesity. |
|
2017 Dec |
Eur J Med Chem |
Synthesis and biological evaluation of new naphtho- and quinolinocyclopentane derivatives as potent melatoninergic (MT1MT2) and serotoninergic (5-HT2C) dual ligands. |
|
2018 |
Psychopharmacology (Berl) |
The 5-HT2C receptor agonist meta-chlorophenylpiperazine (mCPP) reduces palatable food consumption and BOLD fMRI responses to food images in healthy female volunteers. |
|
2017 |
J Psychopharmacol |
Role of impulsivity and reward in the anti-obesity actions of 5-HT2C receptor agonists. |
|
2017 Dec |
Drug Alcohol Depend |
Effects of lorcaserin (Belviq®) on nicotine- and food-maintained responding in non-human primates. |
|
2018 |
Neuropharmacology |
Activation of 5-HT2A receptor disrupts rat maternal behavior. |
|
2017 |
Neuropharmacology |
Serotonin gating of cortical and thalamic glutamate inputs onto principal neurons of the basolateral amygdala. |
|
2017 |
J Labelled Comp Radiopharm |
Synthesis, radiofluorination, and preliminary evaluation of the potential 5-HT2A receptor agonists [18 F]Cimbi-92 and [18 F]Cimbi-150. |
|
2017 |
Adv Exp Med Biol |
Role of 5-HT2 and 5-HT7 Serotonin Receptors, and Protein Kinases C and A on Taurine Transport in Lymphocytes of Rats Treated with Fluoxetine. |
|
2017 |
Expert Rev Clin Pharmacol |
Pimavanserin, a novel antipsychotic for management of Parkinson's disease psychosis. |
|
2017 |
J Womens Health (Larchmt) |
Effect of Flibanserin Treatment on Body Weight in Premenopausal and Postmenopausal Women with Hypoactive Sexual Desire Disorder: A Post Hoc Analysis. |
|
2017 |
Clin Exp Pharmacol Physiol |
5-HT modulates the rat mesenteric vasopressor outflow by 5-HT1D sympatholytic receptors. |
|
2017 |
Br J Pharmacol |
Ameliorative effect of chlorpromazine hydrochloride on visceral hypersensitivity in rats: possible involvement of 5-HT2A receptor. |
|
2017 |
Psychopharmacology (Berl) |
Pharmacological evidence that 5-HT2C receptor blockade selectively improves decision making when rewards are paired with audiovisual cues in a rat gambling task. |
|
2018 |
BJU Int |
Chronic spinal cord injury causes upregulation of serotonin (5-HT)2A and 5-HT2C receptors in lumbosacral cord motoneurons. |
|
2018 |
Curr Top Behav Neurosci |
Hallucinogens and Serotonin 5-HT2A Receptor-Mediated Signaling Pathways. |
|
2017 |
Sex Med Rev |
Flibanserin Efficacy and Safety in Premenopausal Women With Generalized Acquired Hypoactive Sexual Desire Disorder. |
|
2017 Jul |
J Med Chem |
Discovery of N-Substituted (2-Phenylcyclopropyl)methylamines as Functionally Selective Serotonin 2C Receptor Agonists for Potential Use as Antipsychotic Medications. |
|
2017 |
J Pharmacol Sci |
Serotonergic modulation of nicotine-induced kinetic tremor in mice. |
|
2017 Sep |
Drug Alcohol Depend |
Synthetic cathinones and stereochemistry: S enantiomer of mephedrone reduces anxiety- and depressant-like effects in cocaine- or MDPV-abstinent rats. |
|
2017 Jul |
J Med Chem |
Utilization of an Active Site Mutant Receptor for the Identification of Potent and Selective Atypical 5-HT2C Receptor Agonists. |
|
2017 |
Clin Neuropharmacol |
A Retrospective Study of Pimavanserin Use in a Movement Disorders Clinic. |
|
2017 |
J Clin Pharm Ther |
The pharmacodynamic effects of combined administration of flibanserin and alcohol. |
|
2018 |
Drug Test Anal |
Return of the lysergamides. Part IV: Analytical and pharmacological characterization of lysergic acid morpholide (LSM-775). |
|
2017 |
Psychopharmacology (Berl) |
Effects of the serotonin 2C receptor agonist WAY163909 on the abuse-related effects and mesolimbic dopamine neurochemistry induced by abused stimulants in rhesus monkeys. |
|
2017 Aug |
Neuroscience |
Increased temporal discounting after chronic stress in CHL1-deficient mice is reversed by 5-HT2C agonist Ro 60-0175. |
|
2017 |
Arch Oral Biol |
Agomelatine, a MT1MT2 melatonergic receptor agonist with serotonin 5-HT2C receptor antagonistic properties, presses Prevotella intermedia lipopolysaccharide-induced production of proinflammatory mediators in murine macrophages. |
|
2017 May |
Proc Natl Acad Sci U S A |
Experimental evaluation of the generalized vibrational theory of G protein-coupled receptor activation. |
|
2017 May |
Org Biomol Chem |
18F-Labelling of electron rich iodonium ylides: application to the radiosynthesis of potential 5-HT2A receptor PET ligands. |
|
2017 |
Toxicol Pathol |
Regulatory Forum Review*: Utility of in Vitro Secondary Pharmacology Data to Assess Risk of Drug-induced Valvular Heart Disease in Humans: Regulatory Considerations. |
|
2017 May |
ACS Chem Neurosci |
Synthesis and Structure-Activity Relationships of Tool Compounds Based on WAY163909, a 5-HT2C Receptor Agonist. |
|
2017 Feb |
Ugeskr Laeger |
[Flibanserin as pharmacological therapy of inhibited sexual desire in women]. |
|
2017 |
Psychopharmacology (Berl) |
Dreamlike effects of LSD on waking imagery in humans depend on serotonin 2A receptor activation. |
|
2017 |
Neurosci Res |
Interaction between harmane, a class of β-carboline alkaloids, and the CA1 serotonergic system in modulation of memory acquisition. |
|
2017 |
Eur J Neurosci |
A single administration of the hallucinogen, 4-acetoxy-dimethyltryptamine, prevents the shift to a drug-dependent state and the expression of withdrawal aversions in rodents. |
|
2017 Mar |
Int Neurourol J |
Ketanserin and Naftopidil Enhance the Potentiating Effect of Alpha-Methyl-Serotonin on the Neurally-Induced Contraction of Human Isolated Urinary Bladder Muscle Strips. |
|
2017 |
J Pharmacol Exp Ther |
Detailed Characterization of the In Vitro Pharmacological and Pharmacokinetic Properties of iNi-(2-Hydroxybenzyl)-2,5-Dimethoxy-4-Cyanophenylethylamine (25CN-NBOH), a Highly Selective and Brain-Penetrant 5-HT2A Receptor Agonist. |
|
2017 Jun |
Am J Physiol Regul Integr... |
Activation of CB1 receptors by 2-arachidonoylglycerol attenuates vasoconstriction induced by U46619 and angiotensin II in human and rat pulmonary arteries. |
|
2017 May |
ACS Chem Neurosci |
Studies To Examine Potential Tolerability Differences between the 5-HT2C Receptor Selective Agonists Lorcaserin and CP-809101. |
|
2017 Jul |
J Physiol |
Evidence that 5-HT stimulates intracellular Ca2+ signalling and activates pannexin-1 currents in type II cells of the rat carotid body. |
|
2017 |
Neuropsychopharmacology |
5-HT2C Agonists Modulate Schizophrenia-Like Behaviors in Mice. |
|
2017 |
Psychopharmacology (Berl) |
A short history of the 5-HT2C receptor: from the choroid plexus to depression, obesity and addiction treatment. |