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Recent literature: NMDA receptor antagonist
Date Journal Article title
2019 Front Pharmacol S-Sulfocysteine Induces Seizure-Like Behaviors in Zebrafish.
2019 Apr Neurochem Int Blonanserin ameliorates social deficit through dopamine-D3 receptor antagonism in mice administered phencyclidine as an animal model of schizophrenia.
2019 Apr Acta Otolaryngol A new immunohistochemical method to evaluate the development of vestibular compensation after unilateral labyrinthectomy in rats.
2019 Front Physiol Modulation of NMDA-Mediated Clock Resetting in the Suprachiasmatic Nuclei of imPer2i Luc Mouse by Endocannabinoids.
2019 Apr Behav Brain Res Disruption of latent inhibition by chronic phencyclidine pretreatment in rats.
2019 Apr Eur J Pharmacol Neuroprotection of cordycepin in NMDA-induced excitotoxicity by modulating adenosine A1 receptors.
2019 Apr Exp Neurol Excess glutamate secreted from astrocytes drives upregulation of P-glycoprotein in endothelial cells in amyotrophic lateral sclerosis.
2019 Biomed Pharmacother Ketamine-induced antidepressant like effects in mice: A possible involvement of cannabinoid system.
2019 Apr Curr Pharm Des Therapeutic Effect of Novel Antidepressant Drugs Acting at Specific Receptors of Neurotransmitters and Neuropeptides.
2019 Front Pharmacol Repeated Sigma-1 Receptor Antagonist MR309 Administration Modulates Central Neuropathic Pain Development After Spinal Cord Injury in Mice.
2019 Apr Neuropharmacology The novel dehydroepiandrosterone (DHEA) derivative BNN27 counteracts behavioural deficits induced by the NMDA receptor antagonist ketamine in rats.
2019 Apr Ann N Y Acad Sci Methadone's effects on pentylenetetrazole-induced seizure threshold in mice: NMDAopioid receptors and nitric oxide signaling.
2019 Apr Chem Res Toxicol Memantine Is Protective against Cytotoxicity Caused by Lead and Quinolinic Acid in Cultured Rat Embryonic Hippocampal Cells.
2019 Mar Neuropharmacology Persistent activation of histamine H1 receptors in the hippocampal CA1 region enhances NMDA receptor-mediated synaptic excitation and long-term potentiation in astrocyte- and D-serine-dependent manner.
2019 Mar Neuropharmacology The anaesthetic xenon partially restores an amyloid beta-induced impairment in murine hippocampal synaptic plasticity.
2019 Apr Molecules Design, Synthesis, and In Vitro Biological Activities of a Bio-Oxidizable Prodrug to Deliver Both ChEs and DYRK1A Inhibitors for AD Therapy.
2019 J Clin Psychopharmacol Characterization of the Safety and Pharmacokinetic Profile of D-Methadone, a Novel N-Methyl-D-Aspartate Receptor Antagonist in Healthy, Opioid-Naive Subjects: Results of Two Phase 1 Studies.
2019 Mar J Physiol 5-HT2A receptor activation enhances NMDA receptor-mediated glutamate responses through Src kinase in the dendrites of rat jaw-closing motoneurons.
2019 Mar Brain Res NMDA receptor modulation of the pedunculopontine tegmental nucleus underlies the motivational drive for feeding induced by midbrain dopaminergic neurons.
2019 Mar ACS Chem Neurosci WIN 55,212-2 Reverted Pilocarpine-Induced Status Epilepticus Early Changes of the Interaction among 5-HT2CNMDACB1 Receptors in the Rat Hippocampus.
2019 Mar Neurobiol Dis Soluble tau aggregates inhibit synaptic long-term depression and amyloid β-facilitated LTD in vivo.
2019 Neural Plast Memantine Differentially Regulates Tau Phosphorylation Induced by Chronic Restraint Stress of Varying Duration in Mice.
2019 Mar Neurobiol Learn Mem The NMDA receptor antagonist MK-801 fails to impair long-term recognition memory in mice when the state-dependency of memory is controlled.
2019 Mar Mol Psychiatry Neurobiology of rapid-acting antidepressants: convergent effects on GluA1-synaptic function.
2019 Mar Psychopharmacology (Berl) The novel methoxetamine analogs N-ethylnorketamine hydrochloride (NENK), 2-MeO-N-ethylketamine hydrochloride (2-MeO-NEK), and 4-MeO-N-ethylketamine hydrochloride (4-MeO-NEK) elicit rapid antidepressant effects via activation of AMPA and 5-HT2 receptors.
2019 Mar Acta Neuropsychiatr Prelimbic neuronal nitric oxide synthase inhibition exerts antidepressant-like effects independently of BDNF signalling cascades.
2019 Mar Glia Vascular endothelial growth factor increases the function of calcium-impermeable AMPA receptor GluA2 unit in astrocytes via activation of protein kinase C signaling pathway.
2019 Mar Dev Psychobiol Behavioral effects of postnatal ketamine exposure in rhesus macaque infants are dependent on MAOA-LPR genotype.
2019 Mar Proc Natl Acad Sci U S A (i2R,6Ri)-hydroxynorketamine exerts mGlu2 receptor-dependent antidepressant actions.
2019 Front Behav Neurosci A Specific Role of Hippocampal NMDA Receptors and Arc Protein in Rapid Encoding of Novel Environmental Representations and a More General Long-Term Consolidation Function.
2019 Mar Neurobiol Learn Mem Effects of NMDA antagonist dizocilpine (MK-801) are modulated by the number of distractor stimuli in the rodent odor span task of working memory.
2019 CNS Spectr 30 Lumateperone (ITI-007) for the Treatment of Schizophrenia: Overview of Placebo-Controlled Clinical Trials and an Open-label Safety Switching Study.
2019 Mar Neuropsychopharmacology Lithium continuation therapy following ketamine in patients with treatment resistant unipolar depression: a randomized controlled trial.
2019 Medicine (Baltimore) Effects of tramadol on emergence agitation after general anesthesia for nasal surgery: A retrospective cohort study.
2019 Feb Neuroimage Clin A multicenter study of ketamine effects on functional connectivity: Large scale network relationships, hubs and symptom mechanisms.
2019 Mar Pharmacol Ther Fast-acting antidepressant activity of ketamine: highlights on brain serotonin, glutamate, and GABA neurotransmission in preclinical studies.
2019 Mar Proc Natl Acad Sci U S A Cholecystokinin release triggered by NMDA receptors produces LTP and sound-sound associative memory.
2019 Ment Health Clin Evaluation of dextromethorphan with select antidepressant therapy for the treatment of depression in the acute care psychiatric setting.
2019 Mar Hypertens Res Central blockade of the AT1 receptor attenuates pressor effects via reduction of glutamate release and downregulation of NMDAAMPA receptors in the rostral ventrolateral medulla of rats with stress-induced hypertension.
2019 May Bioorg Med Chem Lett Discovery of NR2B-selective antagonists via scaffold hopping and pharmacokinetic profile optimization.
2019 Jun Behav Brain Res Group I metabotropic glutamate receptor antagonists impair discriminability of reinforcer magnitude, but not risky choice, in a probability-discounting task.
2019 CNS Drugs Expanding Role of NMDA Receptor Antagonists in the Management of Pain.
2019 Feb Neurotoxicol Teratol Repeated toluene exposure alters the synaptic transmission of layer 5 medial prefrontal cortex.
2019 Exp Mol Pathol Ketamine inhibits colorectal cancer cells malignant potential via blockage of NMDA receptor.
2019 May Behav Brain Res Hypersynchronicity in the default mode-like network in a neurodevelopmental animal model with relevance for schizophrenia.
2019 Feb J Cell Mol Med The role of LINC00094miR-224-5p (miR-497-5p)Endophilin-1 axis in Memantine mediated protective effects on blood-brain barrier in AD microenvironment.
2019 Front Psychiatry Long-Term NMDAR Antagonism Correlates Weight Loss With Less Eating.
2019 Feb Neurobiol Dis Targeting the glutamatergic system to counteract organophosphate poisoning: A novel therapeutic strategy.
2019 Hear Res Neuroprotective effects of MK-801 on auditory cortex in salicylate-induced tinnitus: Involvement of neural activity, glutamate and ascorbate.
2019 Dose Response Safety and Efficacy of Ketamine Versus Ketamine-Fentanyl-Dexmedetomidine Combination for Anesthesia and Analgesia in Rats.
2019 Feb Transl Psychiatry Downregulation of Npas4 in parvalbumin interneurons and cognitive deficits after neonatal NMDA receptor blockade: relevance for schizophrenia.
2019 Feb Neurosci Lett Behavioral consequences of simultaneous postnatal exposure to MK-801 and static magnetic field in male Wistar rats.
2019 Feb J Dent Res ACC Plasticity Maintains Masseter Hyperalgesia Caused by Occlusal Interference.
2019 Pharmacol Res Perspect Memantine protects thalamocortical hyper-glutamatergic transmission induced by NMDA receptor antagonism via activation of system xclt;gt;.
2019 Pharmacol Res Perspect Binding characterization of N-(2-chloro-5-thiomethylphenyl)-N'-(3-[3 H]3 methoxy phenyl)-N'-methylguanidine ([3 H]GMOM), a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist.
2019 May Behav Brain Res Pharmacological evidence for the relationship between the NMDA receptor and nitric oxide pathway and the antidepressant-like effects of glucagon-like peptide-2 in the mouse forced-swim test.
2019 May J Ethnopharmacol Rhodiola rosea root extract has antipsychotic-like effects in rodent models of sensorimotor gating.
2019 Clin Pharmacol Small-cell lung cancer growth inhibition: synergism between NMDA receptor blockade and chemotherapy.
2019 Feb Eur Neuropsychopharmacol Anxiety during ketamine infusions is associated with negative treatment responses in major depressive disorder.
2019 Exp Eye Res Effects of amantadine on corneal endothelium.
2019 Feb Neurosci Lett Glutaminergic tonic action potentiate MPP+-induced hydroxyl radical production in rat striatum.
2019 Feb Neurol Res COX-2 contributed to the remifentanil-induced hyperalgesia related to ephrinBEphB signaling.
2019 Jun Brain Res Layer-specific involvement of endocannabinoid signaling in muscarinic-induced long-term depression in layer 23 pyramidal neurons of rat visual cortex.
2019 Feb Prog Neuropsychopharmacol... Nitric oxide in the dorsal periaqueductal gray mediates the panic-like escape response evoked by exposure to hypoxia.
2019 Pharmacol Biochem Behav Discriminative stimulus effects of mecamylamine and nicotine in rhesus monkeys: Central and peripheral mechanisms.
2019 Neurochem Int Linking phencyclidine intoxication to the tryptophan-kynurenine pathway: Therapeutic implications for schizophrenia.
2019 Mol Pain Calcitonin gene-related peptide potentiated the excitatory transmission and network propagation in the anterior cingulate cortex of adult mice.
2019 Feb J Neurochem Endogenous transient receptor potential ankyrin 1 and vanilloid 1 activity potentiates glutamatergic input to spinal lamina I neurons in inflammatory pain.
2019 Conscious Cogn Neurochemical models of near-death experiences: A large-scale study based on the semantic similarity of written reports.
2019 Jan J Pain Blockade of NMDA Receptors and Nitric Oxide Synthesis Potentiated Morphine-Induced Anti-Allodynia via Attenuating Pain-Related Amygdala pCREBCREB Signaling Pathway.
2019 Apr Mol Cell Endocrinol Rapid effect of bisphenol A on glutamate-induced Ca2+ influx in hippocampal neurons of rats.
2018 Front Psychiatry EEG 40 Hz Coherence Decreases in REM Sleep and Ketamine Model of Psychosis.
2019 Dtsch Med Wochenschr [Antidementia Drug Therapy of Alzheimer's Dementia: Status 2018 and Outlook].
2019 Apr Neuroscience Progressive Alterations in Synaptic Transmission and Plasticity of Area CA1 Precede the Cognitive Impairment Associated with Neonatal Administration of MK-801.
2019 J Leukoc Biol Tissue-type plasminogen activator neutralizes LPS but not protease-activated receptor-mediated inflammatory responses to plasmin.