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Recent literature: Bone resorption inhibitor
Date Journal Article title
2019 Feb Nutrients Beta-Cryptoxanthin Inhibits Lipopolysaccharide-Induced Osteoclast Differentiation and Bone Resorption via the Suppression of Inhibitor of NF-κB Kinase Activity.
2019 Feb Free Radic Res Glutathione accelerates osteoclast differentiation and inflammatory bone destruction.
2019 Feb Osteoporos Int Association of blood n-3 fatty acid with bone mass and bone marrow TRAP-5b in the elderly with and without hip fracture.
2019 Mar Biochem Biophys Res Commun Proton pumping V-ATPase inhibitor bafilomycin A1 affects Rab7 lysosomal localization and abolishes anterograde trafficking of osteoclast secretory lysosomes.
2019 Tohoku J Exp Med Antiresorptive Agent-Related Osteonecrosis of the Jaw (ARONJ): A Twist of Fate in the Bone.
2019 Feb J Bone Miner Metab Novel bisphosphonate compound FYB-931 preferentially inhibits aortic calcification in vitamin D3-treated rats.
2019 Jan FASEB J Psoralen accelerates bone fracture healing by activating both osteoclasts and osteoblasts.
2019 Mar Biochem Biophys Res Commun Role of ANTXR1 in the regulation of RANKL-induced osteoclast differentiation and function.
2019 Jan Eur J Pharmacol Histone deacetylase inhibitor CI-994 inhibits osteoclastogenesis via pressing NF-κB and the downstream c-FosNFATc1 signaling pathways.
2019 Jan Drug Dev Ind Pharm Bioactive injectable triple acting thermosensitive hydrogel enriched with nano-hydroxyapatite for bone regeneration: in-vitro characterization, Saos-2 cell line cell viability and osteogenic markers evaluation.
2019 Jan Metabolism Extracellular vesicles from human umbilical cord blood ameliorate bone loss in senile osteoporotic mice.
2019 Jan Br J Clin Pharmacol Clinical and translational pharmacology of the cathepsin K inhibitor odanacatib studied for osteoporosis.
2019 Jan J Cell Physiol AZD8835 inhibits osteoclastogenesis and periodontitis-induced alveolar bone loss in rats.
2019 Jan J Med Chem Targeted Endocrine Therapy: Design, Synthesis, and Proof-of-Principle of 17β-Hydroxysteroid Dehydrogenase Type 2 Inhibitors in Bone Fracture Healing.
2018 J Dent Anesth Pain Med Propofol promotes osteoclastic bone resorption by increasing DC-STAMP expression.
2019 Jan J Clin Periodontol Inhibition of Ctsk alleviates periodontitis and comorbid rheumatoid arthritis via downregulation of the TLR9 signaling pathway.
2019 Jan Biomolecules Specialized Roles for Actin in Osteoclasts: Unanswered Questions and Therapeutic Opportunities.
2019 Bone Res Efficacy of an orally active small-molecule inhibitor of RANKL in bone metastasis.
2019 Feb Biochem J Identification of strate-specific inhibitors of cathepsin K through high-throughput screening.
2019 Jan J Bone Miner Res The Novel p38 Inhibitor, Pamapimod, Inhibits Osteoclastogenesis and Counteracts Estrogen-Dependent Bone Loss in Mice.
2019 PLoS One Calcium mimics the chemotactic effect of conditioned media and is an effective inducer of bone regeneration.
2019 Jan J Bone Miner Res Reduction of Cortical Bone Turnover and Erosion Depth After 2 and 3 Years of Denosumab: Iliac Bone Histomorphometry in the FREEDOM Trial.
2019 Int Immunopharmacol Inhibition of tumor necrosis factor-alpha (TNF-alpha) in patients with early rheumatoid arthritis results in acute changes of bone modulators.
2018 Dec J Pharm Pharmacol The antinociceptive effect of resveratrol in bone cancer pain is inhibited by the Silent Information Regulator 1 inhibitor selisistat.
2019 Maturitas New therapeutic targets for osteoporosis.
2019 Bone Acute hypercalcemia and excessive bone resorption following anti-RANKL withdrawal: Case report and brief literature review.
2018 Dec Int J Mol Sci Butyrate Stimulates Histone H3 Acetylation, 8-Isoprostane Production, RANKL Expression, and Regulated Osteoprotegerin ExpressionSecretion in MG-63 Osteoblastic Cells.
2018 Dec FASEB J Prostate transmembrane protein androgen induced 1 is induced by activation of osteoclasts and regulates bone resorption.
2018 Theranostics V-ATPases and osteoclasts: ambiguous future of V-ATPases inhibitors in osteoporosis.
2019 J Bone Miner Res Roles for HB-EGF in Mesenchymal Stromal Cell Proliferation and Differentiation During Skeletal Growth.
2018 Dec J Cell Physiol Mandibular osteotomy-induced hypoxia enhances osteoclast activation and acid secretion by increasing glycolysis.
2019 Feb Cancer Lett Phosphatidyl inositol 3-kinase (PI3K)-mTOR inhibitor PKI-402 inhibits breast cancer induced osteolysis.
2019 Jan Physiol Rev The Activity of Peptides of the Calcitonin Family in Bone.
2018 Dec Curr Pharm Biotechnol Suppressive Effects of the Standardized Extract of Phyllanthus amarus on Type II collagen-induced Rheumatoid Arthritis in Sprague Dawley Rats.
2019 Bone Deletion of OPN in BSP knockout mice does not correct bone hypomineralization but results in high bone turnover.
2018 Dec Calcif Tissue Int Hyperglycemia Induces Osteoclastogenesis and Bone Destruction Through the Activation of Ca2+Calmodulin-Dependent Protein Kinase II.
2018 Nov Molecules Inhibitory Effects of 2N1HIA (2-(3-(2-Fluoro-4-Methoxyphenyl)-6-Oxo-1(6H)-Pyridazinyl)-iNi-1H-Indol-5-Ylacetamide) on Osteoclast Differentiation via Suppressing Cathepsin K Expression.
2018 Nov J Neurosurg ACE-inhibitors: a preventive measure for bone flap resorption after autologous cranioplasty?
2019 J Cell Mol Med Small molecule nAS-E targeting cAMP response element binding protein (CREB) and CREB-binding protein interaction inhibits breast cancer bone metastasis.
2018 Front Pharmacol Targeting Anion Exchange of Osteoclast, a New Strategy for Preventing Wear Particles Induced- Osteolysis.
2018 Nov Mol Cell Biochem Sirtuin 1 inhibits TNF-α-mediated osteoclastogenesis of bone marrow-derived macrophages through both ROS generation and TRPV1 activation.
2019 Mol Med Rep Streptolysin O derived from Streptococcus pyogenes inhibits RANKL‑induced osteoclastogenesis through the NF‑κB signaling pathway.
2019 J Cell Physiol Interleukin-37 inhibits osteoclastogenesis and alleviates inflammatory bone destruction.
2018 Int Immunopharmacol The renin-angiotensin system in the synovium promotes periarticular osteopenia in a rat model of collagen-induced arthritis.
2019 Biomed Pharmacother DPP-4 inhibitor impedes lipopolysaccharide-induced osteoclast formation and bone resorption in vivo.
2018 Nov J Periodontol A novel Bruton's tyrosine kinase inhibitor acalabrutinib presses osteoclast differentiation and P. gingivalis lipopolysaccharide-induced alveolar bone resorption.
2018 Ther Adv Musculoskelet Dis New and emerging concepts in the use of denosumab for the treatment of osteoporosis.
2018 Oct Int J Mol Sci The Bromodomain Inhibitor iNi-Methyl pyrrolidone Prevents Osteoporosis and BMP-Triggered Sclerostin Expression in Osteocytes.
2018 Front Bioeng Biotechnol iIn vitroi Models of Bone Remodelling and Associated Disorders.
2018 Oct J Bone Miner Metab Regulatory mechanisms of sclerostin expression during bone remodeling.
2018 Oct Pharmaceutics Myeloma Bone Disease: Update on Pathogenesis and Novel Treatment Strategies.
2018 Front Cell Dev Biol Thy-1 Deficiency Augments Bone Loss in Obesity by Affecting Bone Formation and Resorption.
2018 Front Immunol Bone Remodeling and the Role of TRAF3 in Osteoclastic Bone Resorption.
2018 Metabolism Overexpression of Sirt1 in mesenchymal stem cells protects against bone loss in mice by FOXO3a deacetylation and oxidative stress inhibition.
2018 Oct J Periodontal Res A novel IkB kinase inhibitor attenuates ligature-induced periodontal disease in mice.
2018 Oct Nat Commun Bone protection by inhibition of microRNA-182.
2018 JBMR Plus Sclerostin Antibody Treatment Stimulates Bone Formation to Normalize Bone Mass in Male Down Syndrome Mice.
2018 Eur Rev Med Pharmacol Sci MiR-203 is essential for the shift from osteogenic differentiation to adipogenic differentiation of mesenchymal stem cells in postmenopausal osteoporosis.
2018 Mol Biol Rep BMAL1 regulates balance of osteogenic-osteoclastic function of bone marrow mesenchymal stem cells in type 2 diabetes mellitus through the NF-κB pathway.
2018 Biomed Pharmacother Beneficial effects of hyperoside on bone metabolism in ovariectomized mice.
2018 Sep J Cell Biochem Osteoprotegerin inhibit osteoclast differentiation and bone resorption by enhancing autophagy via AMPKmTORp70S6K signaling pathway in vitro.
2018 Front Pharmacol Hesperetin Prevents Bone Resorption by Inhibiting RANKL-Induced Osteoclastogenesis and Jnk Mediated Irf-3c-Jun Activation.
2018 Front Pharmacol Ulinastatin Inhibits Osteoclastogenesis and Suppresses Ovariectomy-Induced Bone Loss by Downregulating uPAR.
2018 J Clin Periodontol Melatonin as adjunctive therapy in the treatment of periodontitis associated with obesity.
2018 PLoS One Bone remodeling: A tissue-level process emerging from cell-level molecular algorithms.
2019 J Bone Miner Res TIMP Loss Activates Metalloproteinase-TNFα-DKK1 Axis To Compromise Wnt Signaling and Bone Mass.
2018 Sep Molecules Resveratrol Suppresses Matrix Metalloproteinase-2 Activation Induced by Lipopolysaccharide in Mouse Osteoblasts via Interactions with AMP-Activated Protein Kinase and Suppressor of Cytokine Signaling 1.
2019 Calcif Tissue Int A Mild Inhibition of Cathepsin K Paradoxically Stimulates the Resorptive Activity of Osteoclasts in Culture.
2018 Sep Nephrol Dial Transplant High-serum phosphate and parathyroid hormone distinctly regulate bone loss and vascular calcification in experimental chronic kidney disease.
2018 PLoS One SMAD15 signaling in osteoclasts regulates bone formation via coupling factors.
2018 Gland Surg Osteoporosis and musculoskeletal complications related to therapy of breast cancer.
2018 Aug Sci Rep The osteoprogenitor-specific loss of ephrinB1 results in an osteoporotic phenotype affecting the balance between bone formation and resorption.
2018 PLoS One Minodronate treatment improves low bone mass and reduces progressive thoracic scoliosis in a mouse model of adolescent idiopathic scoliosis.
2018 Br J Oral Maxillofac Surg Cathepsin K inhibitor causes changes in crystallinity and crystal structure of newly-formed mandibular bone in rats.
2018 Sep J Biol Chem The contribution of cross-talk between the cell-surface proteins CD36 and CD47-TSP-1 in osteoclast formation and function.