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Recent literature: Bone resorption inhibitor
Date Journal Article title
2019 Nov Rheumatol Ther Spebrutinib (CC-292) Affects Markers of B Cell Activation, Chemotaxis, and Osteoclasts in Patients with Rheumatoid Arthritis: Results from a Mechanistic Study.
2019 Nov Toxicol Appl Pharmacol Two novel peptides from ark shell protein stimulate osteoblast differentiation and rescue ovariectomy-induced bone loss.
2019 Nov Cell Prolif Suppression of AMP-activated protein kinase reverses osteoprotegerin-induced inhibition of osteoclast differentiation by reducing autophagy.
2019 Nov J Phys Chem B Inhibiting Human Calcitonin Fibril Formation with its Most Relevant Aggregation-Resistant Analog.
2019 Oct Lancet Diabetes Endocrinol Odanacatib for the treatment of postmenopausal osteoporosis: results of the LOFT multicentre, randomised, double-blind, placebo-controlled trial and LOFT Extension study.
2019 Regen Ther An osteogenic helioxanthin derivative presses the formation of bone-resorbing osteoclasts.
2019 J Bone Oncol An exploratory randomized-controlled trial of the efficacy of the Src-kinase inhibitor saracatinib as a novel analgesic for cancer-induced bone pain.
2019 Oct Sci Rep Roles of monocarboxylate transporter types in promotion and pression of osteoclast differentiation and survival on bone.
2019 Oct J Cell Physiol YAP1 inhibits the induction of TNF-α-stimulated bone-resorbing mediators by pressing the NF-κB signaling pathway in MC3T3-E1 cells.
2019 Oct Int J Mol Sci Inhibitory Effects of iNi-[2-(4-acetyl-1-piperazinyl) phenyl]-2-(2-chlorophenoxy) acetamide on Osteoclast Differentiation In Vitro via the Downregulation of TRAF6.
2019 Oct Drug Dev Res Chronic administration of Cl-amidine, a pan-peptidylarginine deiminase inhibitor, does not reverse bone loss in two different murine models of osteoporosis.
2019 Oct J Bone Miner Res Alveolar Bone Protection by Targeting the SH3BP2-SYK Axis in Osteoclasts.
2019 Oct J Bone Miner Res Targeting Bortezomib to Bone Increases its Bone Anabolic Activity and Reduces Systemic Adverse Effects in Mice.
2019 Oct Orthod Craniofac Res Impact of pharmacologic inhibition of tooth movement on periodontal and tooth root tissues during orthodontic force application.
2019 Oct J Clin Med TREM-1 Is Upregulated in Experimental Periodontitis, and Its Blockade Inhibits IL-17A and RANKL Expression and Suppresses Bone loss.
2019 Sep JAMA Netw Open Association of Fat Body Mass With Vertebral Fractures in Postmenopausal Women With Early Breast Cancer Undergoing Adjuvant Aromatase Inhibitor Therapy.
2019 Ann Transl Med Effects of GLP-1 receptor analogue liraglutide and DPP-4 inhibitor vildagliptin on the bone metabolism in ApoE-- mice.
2019 Sep Exp Mol Med Adaptor protein CrkII negatively regulates osteoblast differentiation and function through JNK phosphorylation.
2019 Sep Nutrients Egg White Ovotransferrin Attenuates RANKL-Induced Osteoclastogenesis and Bone Resorption.
2019 Nov Biochem Biophys Res Commun Lung tumor cells inhibit bone mineralization and osteoblast activity.
2019 Sep Cell Biol Int Melatonin promotes osteoblastic differentiation and regulates PDGFAKT signaling pathway.
2019 Sep J Cell Physiol Antiosteoclastic bone resorption activity of osteoprotegerin via enhanced AKTmTORULK1-mediated autophagic pathway.
2019 Sep Endocr J Elevated levels of circulating fibroblast growth factor 23 with hypercalcemia following discontinuation of denosumab.
2019 Sep Int J Biol Macromol Inhibition of protein phosphatase 2A attenuates titanium-particle induced pression of bone formation.
2019 Sep Cell Death Dis The emerging role of IMD 0354 on bone homeostasis by pressing osteoclastogenesis and bone resorption, but without affecting bone formation.
2019 Sep J Bone Miner Res EZH2 Supports Osteoclast Differentiation and Bone Resorption Via Epigenetic and Cytoplasmic Targets.
2019 Sep J Periodontol Occlusal trauma inhibits osteoblast differentiation and bone formation through IKK-NF-κB signaling.
2019 Oxid Med Cell Longev Methylene Blue-Mediated Photodynamic Therapy Induces Macrophage Apoptosis via ROS and Reduces Bone Resorption in Periodontitis.
2019 Front Pharmacol Administration of SB239063 Ameliorates Ovariectomy-Induced Bone Loss iviai Suppressing Osteoclastogenesis in Mice.
2019 Aug Cytokine Proteasome inhibition press microgravity elevated RANK signaling during osteoclast differentiation.
2019 Int Immunopharmacol LDC000067 presses RANKL-induced osteoclastogenesis in vitro and prevents LPS-induced osteolysis in vivo.
2019 Theranostics Licorice isoliquiritigenin-encapsulated mesoporous silica nanoparticles for osteoclast inhibition and bone loss prevention.
2019 Exp Ther Med Eldecalcitol, an active vitamin D analog, effectively prevents cyclophosphamide-induced osteoporosis in rats.
2019 Aug J Periodontol Role of testosterone and androgen receptor in periodontal disease progression in female rats.
2019 Oral Dis JAK2-STAT3 signaling pathway is involved in rat periapical lesions induced by Enterococcus faecalis.
2019 Aug J Med Chem Design, Synthesis, and Biological Characterization of Orally Active 17β-Hydroxysteroid Dehydrogenase Type 2 Inhibitors Targeting the Prevention of Osteoporosis.
2019 J Dent Res Activation of the STAT1 Pathway Accelerates Periodontitis in iNos3--i Mice.
2019 Cell Biochem Funct Suppressive effects of N-bisphosphonate in osteoblastic cells mitigated by non-N-bisphosphonate but not by sodium-dependent phosphate cotransporter inhibitor.
2019 IUBMB Life MicroRNA-155 inhibition up-regulates LEPR to inhibit osteoclast activation and bone resorption via activation of AMPK in alendronate-treated osteoporotic mice.
2019 J Cell Mol Med MicroRNA-92b-5p modulates melatonin-mediated osteogenic differentiation of bone marrow mesenchymal stem cells by targeting ICAM-1.
2019 FASEB J The effects of tranylcypromine on osteoclastogenesis iin vitroi and iin vivoi.
2019 Jul Proc Natl Acad Sci U S A Sfrp4 repression of the Ror2Jnk cascade in osteoclasts protects cortical bone from excessive endosteal resorption.
2019 Int Immunopharmacol Lysophosphatidic acid induces interleukin-6 and CXCL15 secretion from MLO-Y4 cells through activation of the LPA1 receptor and PKCθ signaling pathway.
2019 Sep Exp Cell Res Nirogacestat presses RANKL-Induced osteoclast formation in vitro and attenuates LPS-Induced bone resorption in vivo.
2019 Pharmacol Rep From bone resorption inhibitor to neuroprotective drug: The effects of bisphosphonates.
2019 Case Rep Nephrol Dial Severe, Symptomatic Hypocalcemia due to Denosumab Administration: Treatment and Clinical Course.
2019 Jun Mar Drugs Fucoidan Prevents RANKL-Stimulated Osteoclastogenesis and LPS-Induced Inflammatory Bone Loss via Regulation of AktGSK3βPTENNFATc1 Signaling Pathway and Calcineurin Activity.
2019 Calcif Tissue Int Reversal of Osteopenia in Ovariectomized Rats by Pentoxifylline: Evidence of Osteogenic and Osteo-Angiogenic Roles of the Drug.
2019 J Cancer Res Clin Oncol Targeting cathepsin K diminishes prostate cancer establishment and growth in murine bone.
2019 Int Immunopharmacol Multitarget-based cotreatment with cilostazol and celecoxib synergistically presses collagen-induced arthritis in mice by enhancing interleukin-10 expression.
2019 Jun J Appl Oral Sci Periapical bone response to bacterial lipopolysaccharide is shifted upon cyclooxygenase blockage.
2019 Cancer Treat Rev Management of bone health in solid tumours: From bisphosphonates to a monoclonal antibody.
2019 May Aging (Albany NY) A small molecular inhibitor of LRRK1 identified by homology modeling and virtual screening presses osteoclast function, but not osteoclast differentiation, iin vitroi.
2019 J Bone Miner Res Novel Role for Claudin-11 in the Regulation of Osteoblasts via Modulation of ADAM10-Mediated Notch Signaling.
2019 Jul Biochem Biophys Res Commun Vx-11e protects against titanium-particle-induced osteolysis and osteoclastogenesis by ressing ERK activity.
2019 Jun J Med Chem Development of Small-Molecules Targeting Receptor Activator of Nuclear Factor-κB Ligand (RANKL)-Receptor Activator of Nuclear Factor-κB (RANK) Protein-Protein Interaction by Structure-Based Virtual Screening and Hit Optimization.
2019 Jul Endocrinology Glucocorticoid-Induced Bone Fragility Is Prevented in Female Mice by Blocking Pyk2Anoikis Signaling.
2019 J Periodontol Effects of topical application of 1% sodium alendronate gel in the surgical treatment of periodontal intrabony defects: A 6-month randomized controlled clinical trial.
2019 May Sci Rep Specific targeting of PKCδ presses osteoclast differentiation by accelerating proteolysis of membrane-bound macrophage colony-stimulating factor receptor.
2019 Apr BMC Mol Cell Biol Compression and tension variably alter Osteoprotegerin expression via miR-3198 in periodontal ligament cells.
2019 Bone Agonist-induced activation of the S1P receptor 2 constitutes a novel osteoanabolic therapy for the treatment of osteoporosis in mice.
2019 J Cell Physiol LY411575, a potent γ-secretase inhibitor, presses osteoclastogenesis in vitro and LPS-induced calvarial osteolysis in vivo.
2019 J Bone Miner Res An Ectosteric Inhibitor of Cathepsin K Inhibits Bone Resorption in Ovariectomized Mice.
2019 Apr JCI Insight Activation of the calcium sensing receptor attenuates TRPV6-dependent intestinal calcium absorption.
2019 J Bone Oncol Plasma levels of Semaphorin 4D are decreased by adjuvant tamoxifen but not aromatase inhibitor therapy in breast cancer patients.
2019 May J Endocr Soc The Bone Phenotype and Pain Response to Pamidronate in Tyrosine Kinase Inhibitor-Treated Chronic Myelogenous Leukemia.
2019 Phytomedicine Longan fruit increase bone mineral density in zebrafish and ovariectomized rat by pressing RANKL-induced osteoclast differentiation.
2019 Apr JCI Insight Sclerostin inhibition alleviates breast cancer-induced bone metastases and muscle weakness.
2019 Expert Opin Pharmacother Current and emerging osteoporosis pharmacotherapy for women: state of the art therapies for preventing bone loss.
2019 Bone Rep Bruton's tyrosine kinase (Btk) inhibitor tirabrutinib presses osteoclastic bone resorption.
2019 J Bone Oncol Dovitinib dilactic acid reduces tumor growth and tumor-induced bone changes in an experimental breast cancer bone growth model.
2019 Biomed Res Int Positive Correlation between Activated CypACD147 Signaling and MMP-9 Expression in Mice Inflammatory Periapical Lesion.
2019 Jpn Dent Sci Rev Imaging modalities for drug-related osteonecrosis of the jaw (2), Overview of the position paper on medication-related osteonecrosis of the jaw and the current status of the MRONJ in Japan.
2019 Basic Clin Pharmacol Toxicol Lansoprazole inhibits the cysteine protease legumain by binding to the active site.
2019 Bone Vibration enhances osteoclastogenesis by inducing RANKL expression via NF-κB signaling in osteocytes.