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Recent literature: Bone resorption inhibitor
Date Journal Article title
2020 Mar J Bone Miner Res Ubiquitin-specific protease 34 inhibits osteoclast differentiation by regulating NF-κB signaling.
2020 Mar Biomed Pharmacother Autophagy negative-regulating Wnt signaling enhanced inflammatory osteoclastogenesis from Pre-OCs in vitro.
2020 Int J Rheumatol Role of Secreted Frizzled-Related Protein 1 and Tumor Necrosis Factor-iαi (TNF-iαi) in Bone Loss of Patients with Rheumatoid Arthritis.
2020 Mar Free Radic Res Inhibition of MEKERK upregulates GSH production and increases RANKL-induced osteoclast differentiation in RAW 264.7 cells.
2020 Mar Bone A novel inhibitor of NF-κB-inducing kinase prevents bone loss by inhibiting osteoclastic bone resorption in ovariectomized mice.
2020 Mar J Periodontal Res Glyburide inhibits the bone resorption induced by traumatic occlusion in rats.
2020 Mar Calcif Tissue Int Modulation of Transient Receptor Potential Channels 3 and 6 Regulates Osteoclast Function with Impact on Trabecular Bone Loss.
2020 Acta Pharm Sin B Benzydamine inhibits osteoclast differentiation and bone resorption iviai down-regulation of interleukin-1 ibiβib i expression.
2020 Feb Bone Skeletal restoration by phosphodiesterase 5 inhibitors in osteopenic mice: Evidence of osteoanabolic and osteoangiogenic effects of the drugs.
2020 Feb J Dent Res Indigenous Microbiota Protects against Inflammation-Induced Osteonecrosis.
2020 Feb Sci Rep C-phycocyanin attenuates RANKL-induced osteoclastogenesis and bone resorption in vitro through inhibiting ROS levels, NFATc1 and NF-κB activation.
2020 Feb Cell Biol Int Murine osteoclastogenesis pression using conditioned media produced by melanoma or activated and non-activated Jurkat-E6 cells.
2020 Jan Cancers (Basel) Ixazomib Improves Bone Remodeling and Counteracts sonic Hedgehog signaling Inhibition Mediated by Myeloma Cells.
2020 Mol Med Rep miR‑21 promotes osteoclastogenesis through activation of PI3KAkt signaling by targeting Pten in RAW264.7 cells.
2020 Jan J Bone Miner Res A Pooled Analysis of Fall Incidence From Placebo-controlled Trials of Denosumab.
2020 Mar Exp Cell Res PP121 presses RANKL-Induced osteoclast formation in vitro and LPS-Induced bone resorption in vivo.
2020 FASEB J High shear stress amplitude in combination with prolonged stimulus duration determine induction of osteoclast formation by hematopoietic progenitor cells.
2019 Mediators Inflamm Concomitant Treatment with Etanercept and Tacrolimus Synergistically Attenuates Arthritis Progression via Inhibition of Matrix Metalloproteinase-3 Production and Osteoclastogenesis in Human TNF-iαi Transgenic Mice.
2020 Jan Sci Rep Hyaluronan presses enhanced cathepsin K expression via activation of NF-κB with mechanical stress loading in a human chondrocytic HCS-28 cells.
2019 Front Immunol Loss of Dkk-1 in Osteocytes Mitigates Alveolar Bone Loss in Mice With Periodontitis.
2020 Jan Med Sci Monit Fluid Shear Stress Suppresses Osteoclast Differentiation in RAW264.7 Cells through Extracellular Signal-Regulated Kinase 5 (ERK5) Signaling Pathway.
2020 Nurs Womens Health New Osteoporosis Treatment Means New Bone Formation.
2020 Thromb Res Inhibitory effects of dabigatran etexilate, a direct thrombin inhibitor, on osteoclasts and osteoblasts.
2020 Calcif Tissue Int Effects of Long-Term Sclerostin Deficiency on Trabecular Bone Mass and Adaption to Limb Loading Differ in Male and Female Mice.
2019 Dec Arthritis Res Ther Pharmacological inhibition of TAK1, with the selective inhibitor takinib, alleviates clinical manifestation of arthritis in CIA mice.
2019 Dec J Bone Miner Res Inhibition of Osteoclastogenesis by the RNA-Binding Protein QKI5: a Novel Approach to Protect from Bone Resorption.
2019 Oxid Med Cell Longev Dnmt3a-Mediated DNA Methylation Changes Regulate Osteogenic Differentiation of hMSCs Cultivated in the 3D Scaffolds under Oxidative Stress.
2019 Nov Immunobiology Potential anti-arthritic and anti-inflammatory effects of TNF-α processing inhibitor-1 (TAPI-1): A new approach to the treatment of S. aureus arthritis.
2020 Small A New NLRP3 Inflammasome Inhibitor, Dioscin, Promotes Osteogenesis.
2019 Dec AAPS PharmSciTech QbD Approach for Novel Crosslinker-Free Ionotropic Gelation of Risedronate Sodium-Chitosan Nebulizable Microspheres: Optimization and Characterization.
2020 Mol Cancer Ther A Novel Sulforaphane-Regulated Gene Network in Suppression of Breast Cancer-Induced Osteolytic Bone Resorption.
2020 Biochim Biophys Acta Prot... Rat cathepsin K: Enzymatic specificity and regulation of its collagenolytic activity.
2020 Rheumatol Ther Spebrutinib (CC-292) Affects Markers of B Cell Activation, Chemotaxis, and Osteoclasts in Patients with Rheumatoid Arthritis: Results from a Mechanistic Study.
2019 Dec Toxicol Appl Pharmacol Two novel peptides from ark shell protein stimulate osteoblast differentiation and rescue ovariectomy-induced bone loss.
2020 Cell Prolif Suppression of AMP-activated protein kinase reverses osteoprotegerin-induced inhibition of osteoclast differentiation by reducing autophagy.
2019 Dec J Phys Chem B Inhibiting Human Calcitonin Fibril Formation with Its Most Relevant Aggregation-Resistant Analog.
2019 Lancet Diabetes Endocrinol Odanacatib for the treatment of postmenopausal osteoporosis: results of the LOFT multicentre, randomised, double-blind, placebo-controlled trial and LOFT Extension study.
2019 Regen Ther An osteogenic helioxanthin derivative presses the formation of bone-resorbing osteoclasts.
2019 J Bone Oncol An exploratory randomized-controlled trial of the efficacy of the Src-kinase inhibitor saracatinib as a novel analgesic for cancer-induced bone pain.
2019 Oct Sci Rep Roles of monocarboxylate transporter types in promotion and pression of osteoclast differentiation and survival on bone.
2019 Oct Molecules Icariin Promotes the Osteogenic Action of BMP2 by Activating the cAMP Signaling Pathway.
2020 J Cell Physiol YAP1 inhibits the induction of TNF-α-stimulated bone-resorbing mediators by pressing the NF-κB signaling pathway in MC3T3-E1 cells.
2019 Oct Int J Mol Sci Inhibitory Effects of iNi-[2-(4-acetyl-1-piperazinyl) phenyl]-2-(2-chlorophenoxy) acetamide on Osteoclast Differentiation In Vitro via the Downregulation of TRAF6.
2020 Drug Dev Res Chronic administration of Cl-amidine, a pan-peptidylarginine deiminase inhibitor, does not reverse bone loss in two different murine models of osteoporosis.
2020 J Bone Miner Res Alveolar Bone Protection by Targeting the SH3BP2-SYK Axis in Osteoclasts.
2020 J Bone Miner Res Targeting Bortezomib to Bone Increases Its Bone Anabolic Activity and Reduces Systemic Adverse Effects in Mice.
2019 Oct Nat Commun HIF1α inhibition facilitates Leflunomide-AHR-CRP signaling to attenuate bone erosion in CRP-aberrant rheumatoid arthritis.
2020 Orthod Craniofac Res Impact of pharmacologic inhibition of tooth movement on periodontal and tooth root tissues during orthodontic force application.
2019 Oct J Clin Med TREM-1 Is Upregulated in Experimental Periodontitis, and Its Blockade Inhibits IL-17A and RANKL Expression and Suppresses Bone loss.
2019 Sep JAMA Netw Open Association of Fat Body Mass With Vertebral Fractures in Postmenopausal Women With Early Breast Cancer Undergoing Adjuvant Aromatase Inhibitor Therapy.
2019 Ann Transl Med Effects of GLP-1 receptor analogue liraglutide and DPP-4 inhibitor vildagliptin on the bone metabolism in ApoE-- mice.
2019 Sep Exp Mol Med Adaptor protein CrkII negatively regulates osteoblast differentiation and function through JNK phosphorylation.
2019 Sep Nutrients Egg White Ovotransferrin Attenuates RANKL-Induced Osteoclastogenesis and Bone Resorption.
2019 Nov Biochem Biophys Res Commun Lung tumor cells inhibit bone mineralization and osteoblast activity.
2020 Cell Biol Int Melatonin promotes osteoblastic differentiation and regulates PDGFAKT signaling pathway.
2020 J Cell Physiol Antiosteoclastic bone resorption activity of osteoprotegerin via enhanced AKTmTORULK1-mediated autophagic pathway.
2020 Jan Endocr J Elevated levels of circulating fibroblast growth factor 23 with hypercalcemia following discontinuation of denosumab.
2020 Jan Int J Biol Macromol Inhibition of protein phosphatase 2A attenuates titanium-particle induced pression of bone formation.
2019 Sep Cell Death Dis The emerging role of IMD 0354 on bone homeostasis by pressing osteoclastogenesis and bone resorption, but without affecting bone formation.
2020 J Bone Miner Res EZH2 Supports Osteoclast Differentiation and Bone Resorption Via Epigenetic and Cytoplasmic Targets.
2019 Sep J Periodontol Occlusal trauma inhibits osteoblast differentiation and bone formation through IKK-NF-κB signaling.
2019 Oxid Med Cell Longev Methylene Blue-Mediated Photodynamic Therapy Induces Macrophage Apoptosis via ROS and Reduces Bone Resorption in Periodontitis.
2019 Front Pharmacol Administration of SB239063 Ameliorates Ovariectomy-Induced Bone Loss iviai Suppressing Osteoclastogenesis in Mice.
2020 Cytokine Proteasome inhibition press microgravity elevated RANK signaling during osteoclast differentiation.
2019 Int Immunopharmacol LDC000067 presses RANKL-induced osteoclastogenesis in vitro and prevents LPS-induced osteolysis in vivo.
2019 Theranostics Licorice isoliquiritigenin-encapsulated mesoporous silica nanoparticles for osteoclast inhibition and bone loss prevention.
2019 Exp Ther Med Eldecalcitol, an active vitamin D analog, effectively prevents cyclophosphamide-induced osteoporosis in rats.
2019 Aug J Periodontol Role of testosterone and androgen receptor in periodontal disease progression in female rats.
2019 Oral Dis JAK2-STAT3 signaling pathway is involved in rat periapical lesions induced by Enterococcus faecalis.
2019 Aug J Med Chem Design, Synthesis, and Biological Characterization of Orally Active 17β-Hydroxysteroid Dehydrogenase Type 2 Inhibitors Targeting the Prevention of Osteoporosis.
2019 J Dent Res Activation of the STAT1 Pathway Accelerates Periodontitis in iNos3--i Mice.
2019 Cell Biochem Funct Suppressive effects of N-bisphosphonate in osteoblastic cells mitigated by non-N-bisphosphonate but not by sodium-dependent phosphate cotransporter inhibitor.
2019 IUBMB Life MicroRNA-155 inhibition up-regulates LEPR to inhibit osteoclast activation and bone resorption via activation of AMPK in alendronate-treated osteoporotic mice.
2019 J Cell Mol Med MicroRNA-92b-5p modulates melatonin-mediated osteogenic differentiation of bone marrow mesenchymal stem cells by targeting ICAM-1.
2019 FASEB J The effects of tranylcypromine on osteoclastogenesis iin vitroi and iin vivoi.