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Recent literature: Dipeptidyl peptidase 4 inhibitor
Date Journal Article title
2019 Feb Eur J Pharmacol The effect of exenatide (a GLP-1 analog) and sitagliptin (a DPP-4 inhibitor) on plasma platelet-activating factor acetylhydrolase (PAF-AH) activity and concentration in normal and fructose-fed rats.
2019 Feb Am J Cardiovasc Drugs Cardiovascular Protection with Anti-hyperglycemic Agents.
2019 Feb Heart Vessels Liraglutide presses atrial electrophysiological changes.
2019 PLoS One Use of non-insulin diabetes medicines after insulin initiation: A retrospective cohort study.
2019 PLoS One Second-line glucose-lowering drugs added to metformin and the risk of hospitalization for heart failure: A nationwide cohort study.
2019 Int J Cardiol Heart Vasc The effect of DPP-4-protected GLP-1 (7-36) on coronary microvascular function in obese adults.
2019 Feb Pharmacoepidemiol Drug Saf Use of dipeptidyl peptidase-4 inhibitors and the risk of arthralgia: Population-based cohort and nested case-control studies.
2019 Feb Drug Dev Res Protective role of sitagliptin against oxidative stress in a kainic acid-induced status epilepticus in rats models via Nrf2HO-1 pathway.
2019 Jan Prim Care Diabetes Network meta-analysis of nine large cardiovascular outcome trials of new antidiabetic drugs.
2019 Jan Clin Ther Effects of Sodium-glucose Cotransporter 2 Inhibitor Monotherapy on Weight Changes in Patients With Type 2 Diabetes Mellitus: a Bayesian Network Meta-analysis.
2019 Feb Inflammation DPP-4 Inhibition Leads to Decreased Pancreatic Inflammatory Profile and Increased Frequency of Regulatory T Cells in Experimental Type 1 Diabetes.
2019 J Clin Med Res Investigation of a Dipeptidyl Peptidase-4 InhibitorThiazolidinedione Combination Drug for Patients With Type 2 Diabetes and Poor Glycemic Control: Difficulty With Patient Enrollment.
2019 Jan Ann Pharmacother Dipeptidyl Peptidase-4 Inhibitors and Inflammatory Bowel Disease Risk: A Meta-analysis.
2019 Jan Nephron Amelioration of Early Markers of Diabetic Nephropathy by Linagliptin in Fructose-Streptozotocin-Induced Type 2 Diabetic Rats.
2019 Jan Carcinogenesis The CD26DPP4-inhibitor vildagliptin presses lung cancer growth via macrophage-mediated NK cell activity.
2019 Jan Diabetes Obes Metab Sodium-Glucose Cotransporter-2 Inhibitor Use and Risk of Lower-Extremity Amputation: Evolving Questions, Evolving Answers.
2019 Jan Endocr Connect Incretin-based therapies for patients with type 1 diabetes: a meta-analysis.
2019 Feb J Med Chem Discovery of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment of Type 2 Diabetes.
2019 Jan Diabetes Ther Ertugliflozin Compared to Other Anti-hyperglycemic Agents as Monotherapy and Add-on Therapy in Type 2 Diabetes: A Systematic Literature Review and Network Meta-Analysis.
2019 Jan Diabetes Metab J Predictors of the Therapeutic Efficacy and Consideration of the Best Combination Therapy of Sodium-Glucose Co-transporter 2 Inhibitors.
2019 Jan J Pain Palliat Care Pharm... The Association of Joint Pain and Dipeptidyl Peptidase-4 Inhibitor Use Among U.S. Adults With Type-2 Diabetes Mellitus.
2019 Jan Br J Dermatol Epitope spreading phenomena in dipeptidyl peptidase-4 inhibitor-associated bullous pemphigoid.
2019 Jan J Health Popul Nutr Comparison of biochemical parameters among DPP4 inhibitor users and other oral hypoglycaemic drug users: a cross-sectional study from Anuradhapura, Sri Lanka.
2019 Yonsei Med J Signal Detection for Cardiovascular Adverse Events of DPP-4 Inhibitors Using the Korea Adverse Event Reporting System Database, 2008-2016.
2019 Mol Immunol Anagliptin ameliorates high glucose- induced endothelial dysfunction via pression of NLRP3 inflammasome activation mediated by SIRT1.
2019 Jan Int J Mol Sci A Novel Dipeptidyl Peptidase IV Inhibitory Tea Peptide Improves Pancreatic β-Cell Function and Reduces α-Cell Proliferation in Streptozotocin-Induced Diabetic Mice.
2019 Feb Bioorg Med Chem Identification of novel uracil derivatives incorporating benzoic acid moieties as highly potent Dipeptidyl Peptidase-IV inhibitors.
2019 Jan Eur J Pharmacol The DPP-4 inhibitor saxagliptin ameliorates ox-LDL-induced endothelial dysfunction by regulating AP-1 and NF-κB.
2019 J Pharmacol Sci A dipeptidyl peptidase-4 (DPP-4) inhibitor, linagliptin, attenuates cardiac dysfunction after myocardial infarction independently of DPP-4.
2019 Jan J Biomed Sci Glucagon-like peptide-1 (GLP-1) mediates the protective effects of dipeptidyl peptidase IV inhibition on pulmonary hypertension.
2019 Jan J Cardiovasc Pharmacol Ther The Role of Vildagliptin in Treating Hypertension Through Modulating Serum VEGF in Diabetic Hypertensive Patients.
2018 Int J Endocrinol A Dipeptidyl Peptidase-4 Inhibitor Suppresses Macrophage Foam Cell Formation in Diabetic idbdbi Mice and Type 2 Diabetes Patients.
2019 Jan Nephrol Dial Transplant Dipeptidyl peptidase-4 inhibitor teneligliptin accelerates recovery from cisplatin-induced acute kidney injury by attenuating inflammation and promoting tubular regeneration.
2019 Jan JAMA Dermatol Association of Dipeptidyl Peptidase 4 Inhibitor Use With Risk of Bullous Pemphigoid in Patients With Diabetes.
2019 Jan BMC Endocr Disord All-cause mortality of insulin plus dipeptidyl peptidase-4 inhibitors in persons with type 2 diabetes.
2019 Jan ChemMedChem An Overview, Advantages and Therapeutic Potential of Nonpeptide Positive Allosteric Modulators of Glucagon-Like Peptide-1 Receptor.
2019 Jan Curr Pharm Biotechnol Hyperglycemia and diabetes induced by glucocorticoids in nondiabetic and diabetic patients: revision of literature and personal considerations.
2019 Jan Am J Physiol Gastrointest... Intestinal TGR5 agonism improves hepatic steatosis and insulin sensitivity in Western diet-fed mice.
2018 Diabetol Int Efficacy and safety of nateglinide plus sitagliptin combination therapy in type 2 diabetes patients inadequately controlled by sitagliptin monotherapy: a phase 3, multicenter, open-label, long-term study.
2018 Medicine (Baltimore) Cardiovascular risk of sitagliptin in ischemic stroke patients with type 2 diabetes and chronic kidney disease: A nationwide cohort study.
2018 Dec Curr Res Transl Med Biological function of dipeptidyl peptidase-4 on type 2 diabetes patients and diabetic mice.
2018 Dec Cardiovasc Diabetol Alogliptin prevents diastolic dysfunction and preserves left ventricular mitochondrial function in diabetic rabbits.
2019 J Manag Care Spec Pharm Implications of Removing Rosiglitazone's Black Box Warning and Restricted Access Program on the Uptake of Thiazolidinediones and Dipeptidyl Peptidase-4 Inhibitors Among Patients with Type 2 Diabetes.
2019 Jan Circulation Linagliptin Effects on Heart Failure and Related Outcomes in Individuals With Type 2 Diabetes Mellitus at High Cardiovascular and Renal Risk in CARMELINA.
2019 Feb Cancer Res Inhibition of Dipeptidyl Peptidase-4 Accelerates Epithelial-Mesenchymal Transition and Breast Cancer Metastasis via the CXCL12CXCR4mTOR Axis.
2018 Dec Diabet Med Effects of saxagliptin on adipose tissue inflammation and vascular function in overweight and obese people: a placebo-controlled study.
2019 Int J Clin Pharmacol Ther Pharmacokinetic comparison of gemigliptin 50 mg and metformin 500 mg as a fixed-dose combination and loose combination
2019 Drug Metab Dispos Gas-Phase Rearrangement of the iOi-Glucuronide of Vildagliptin Forms Product-Ion Fragments Suggesting Wrongly an iNi-Glucuronide.
2019 Jan J Endocr Soc Postprandial Plasma Glucagon Kinetics in Type 2 Diabetes Mellitus: Comparison of Immunoassay and Mass Spectrometry.
2019 Biomed Pharmacother Dipeptidyl peptidase-4 inhibition protects the liver of insulin-resistant female rats against triglyceride accumulation by pressing uric acid.
2019 Biomed Pharmacother The renoprotective effect of the dipeptidyl peptidase-4 inhibitor sitagliptin on adenine-induced kidney disease in rats.
2018 Dec J Invest Dermatol Higher frequency of dipeptidyl peptidase IV inhibitor intake in bullous pemphigoid patients than in the French general population.
2018 Dec J Hypertens Hemodynamic effects of the dipeptidyl peptidase-4 inhibitor linagliptin with renin-angiotensin system inhibitors in type 2 diabetic patients with albuminuria.
2018 Dec Clin Infect Dis A Randomized, Double-Blinded, Placebo-Controlled Trial of Sitagliptin for Reducing Inflammation and Immune Activation in Treated and Suppressed HIV Infection.
2018 Ann Saudi Med A short-term follow-up of glycemic and body weight changes in diabetic patients who replaced dipeptidyl peptidase-4 inhibitors with the sodium-glucose cotransporter 2.
2019 Drug Metab Dispos Hydrolytic Metabolism of Cyanopyrrolidine DPP-4 Inhibitors Mediated by Dipeptidyl Peptidases.
2018 Dec J Diabetes Combined effect of GABA and glucagon-like peptide-1 receptor agonist on cytokine-induced apoptosis in pancreatic β-cell line and isolated human islets.
2018 Clin Epidemiol Factors associated with choice of intensification treatment for type 2 diabetes after metformin monotherapy: a cohort study in UK primary care.
2019 Diabetes Ther Differential Effects of Thiazolidinediones and Dipeptidyl Peptidase-4 Inhibitors on Insulin Resistance and β-Cell Function in Type 2 Diabetes Mellitus: A Propensity Score-Matched Analysis.
2018 Dec J Obstet Gynaecol Res Effects of dipeptidyl peptidase-4 inhibitors on transforming growth factor-β1 signal transduction pathways in the ovarian fibrosis of polycystic ovary syndrome rats.
2018 Nov Clin Pharmacol Drug Dev Pharmacokinetic Interaction Study Between Saxagliptin and Omeprazole, Famotidine, or Magnesium and Aluminum Hydroxides Plus Simethicone in Healthy Subjects: An Open-Label Randomized Crossover Study.
2019 Mol Metab Fibroblast activation protein is dispensable for control of glucose homeostasis and body weight in mice.
2018 Oct Diabetes Metab Effects of glucose-lowering agents on surrogate endpoints and hard clinical renal outcomes in patients with type 2 diabetes.
2018 BMB Rep Role of dipeptidyl peptidase-4 as a potentiator of activinnodal signaling pathway.
2015 Oct Pharmacoeconomic Review R...
2018 Nov Curr Med Res Opin Comparison of the persistence and adherence between fixed-dose combinations and two-pill combinations in Japanese patients with type 2 diabetes.
2018 Nov Diabetes Obes Metab Impact of metformin use on the cardiovascular effects of dipeptidyl peptidase-4 inhibitors: An analysis of Medicare claims data from 2007 to 2015.
2019 Transl Res Small molecule inhibition of dipeptidyl peptidase-4 enhances bone marrow progenitor cell function and angiogenesis in diabetic wounds.
2018 Nov Vascul Pharmacol Alogliptin improves endothelial function by promoting autophagy in perivascular adipose tissue of obese mice through a GLP-1-dependent mechanism.
2018 Nov Mol Cell Biochem Neuroprotective influence of sitagliptin against cisplatin-induced neurotoxicity, biochemical and behavioral alterations in Wistar rats.
2019 J Cell Mol Med Vildagliptin improves high glucose-induced endothelial mitochondrial dysfunction via inhibiting mitochondrial fission.
2018 Medicine (Baltimore) Comparison of dipeptidyl peptidase-4 inhibitors and pioglitazone combination therapy versus pioglitazone monotherapy in type 2 diabetes: A system review and meta-analysis.
2018 Nov JAMA Effect of Linagliptin vs Placebo on Major Cardiovascular Events in Adults With Type 2 Diabetes and High Cardiovascular and Renal Risk: The CARMELINA Randomized Clinical Trial.
2018 FEBS Open Bio The dipeptidyl peptidase-4 (DPP-4) inhibitor teneligliptin enhances brown adipose tissue function, thereby preventing obesity in mice.