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Recent literature: 5-HT3 receptor antagonist
Date Journal Article title
2020 Mar Pflugers Arch Neural regulation of the contractility of nutrient artery in the guinea pig tibia.
2020 Oncologist Phase IIIb Safety and Efficacy of Intravenous NEPA for Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV) in Patients with Breast Cancer Receiving Initial and Repeat Cycles of Anthracycline and Cyclophosphamide (AC) Chemotherapy.
2019 Afr Health Sci Comparison of weight-adjusted dose versus fixed dose ondansetron in preventing shivering following spinal anaesthesia for caesarean deliveries.
2020 F1000Res Countering opioid-induced respiratory depression by non-opioids that are respiratory stimulants.
2020 ESMO Open Olanzapine combined with 5-hydroxytryptamine type 3 receptor antagonist (5-HT3 RA) plus dexamethasone for prevention and treatment of chemotherapy-induced nausea and vomiting in high and moderate emetogenic chemotherapy: a systematic review and meta-analysis of randomised controlled trials.
2020 Oncologist A Nationwide, Multicenter Registry Study of Antiemesis for Carboplatin-Based Chemotherapy-Induced Nausea and Vomiting in Japan.
2020 Invest New Drugs Mirtazapine, a dopamine receptor inhibitor, as a secondary prophylactic for delayed nausea and vomiting following highly emetogenic chemotherapy: an open label, randomized, multicenter phase III trial.
2020 Ann Hematol Antiemetic prophylaxis in patients undergoing hematopoietic stem cell transplantation: a multicenter survey of the Gruppo Italiano Trapianto Midollo Osseo (GITMO) transplant programs.
2020 Feb Can J Physiol Pharmacol Pharmacokinetic profile of the selective 5-HT3 receptor antagonist ondansetron in the rat: an original study and a mini-review of the behavioural pharmacological literature in the rat.
2020 Jan Neurogastroenterol Motil Pharmacological evaluation of a novel corticotrophin-releasing factor 1 receptor antagonist T-3047928 in stress-induced animal models in a comparison with alosetron.
2020 Drug Dev Ind Pharm Sustained release formulation of Ondansetron HCl using osmotic drug delivery approach.
2020 Int Immunopharmacol Involvement of endocannabinoid system, inflammation and apoptosis in diabetes induced liver injury: Role of 5-HT3 receptor antagonist.
2020 Mar Eur J Pharmacol Ondansetron, a highly selective 5-HT3 receptor antagonist, reduces L-DOPA-induced dyskinesia in the 6-OHDA-lesioned rat model of Parkinson's disease.
2019 Dec Chin Clin Oncol A narrative review of tropisetron and palonosetron for the control of chemotherapy-induced nausea and vomiting.
2019 Dec Sci Rep Mild Traumatic Brain Injury Causes Nociceptive Sensitization through Spinal Chemokine Upregulation.
2019 Exp Ther Med Antidepressant effect of the interaction of fluoxetine with granisetron.
2019 Dec Eur J Pharmacol Δ9-THC and related cannabinoids press stance P- induced neurokinin NK1-receptor-mediated vomiting via activation of cannabinoid CB1 receptor.
2020 Jan Biochem Biophys Res Commun α7-Nicotinic acetylcholine receptor antagonist QND7 presses non-small cell lung cancer cell proliferation and migration via inhibition of AktmTOR signaling.
2020 Adv Ther Current US Food and Drug Administration-Approved Pharmacologic Therapies for the Treatment of Irritable Bowel Syndrome with Diarrhea.
2019 Dec J Reprod Dev Effects of 5-hydroxytryptamine on spermatozoal hyperactivation and in vitro fertilization in mice.
2019 Oct Oncologist A Nationwide, Multicenter Registry Study of Antiemesis for Carboplatin-Based Chemotherapy-Induced Nausea and Vomiting in Japan.
2019 Gan To Kagaku Ryoho [Multi-Center Joint Study on the Survey of Antiemetic Therapy for the Prevention of Nausea and Vomiting in Combination Therapy with a Mild Emetic Antineoplastic Drug].
2019 Front Pharmacol Antipsychotic Treatment of Behavioral and Psychological Symptoms of Dementia (BPSD): Management of Extrapyramidal Side Effects.
2019 J Psychopharmacol Fluvoxamine combination therapy with tropisetron for obsessive-compulsive disorder patients: A placebo-controlled, randomized clinical trial.
2019 J Physiol Serotonin exerts a direct modulatory role on bladder afferent firing in mice.
2019 Sep J Clin Med Anti-Tumor Potential of a 5-HT3 Receptor Antagonist as a Novel Autophagy Inducer in Lung Cancer: A Retrospective Clinical Study with In Vitro Confirmation.
2019 Aug Trials Treatment of irritable bowel syndrome with diarrhoea using titrated ondansetron (TRITON): study protocol for a randomised controlled trial.
2019 Int Rev Neurobiol Neuroprotective effects of 5-HT3 receptor antagonist ondansetron on morphine withdrawal induced brain edema formation, blood-brain barrier dysfunction, neuronal injuries, glial activation and heat shock protein upregulation in the brain.
2019 Aliment Pharmacol Ther Abnormalities of mucosal serotonin metabolism and 5-HT3 receptor unit 3C polymorphism in irritable bowel syndrome with diarrhoea predict responsiveness to ondansetron.
2019 J Biochem Mol Toxicol Ondansetron enhanced diclofenac-induced nephrotoxicity in mice.
2019 Oct J Pharm Biomed Anal Highly sensitive HPLC-MSMS assay for the quantitation of ondansetron in rat plasma and rat brain tissue homogenate following administration of a very low cutaneous dose.
2019 Oct Eur J Pharmacol Mirtazapine increases glial cell line-derived neurotrophic factor production through lysophosphatidic acid 1 receptor-mediated extracellular signal-regulated kinase signaling in astrocytes.
2019 J Anaesthesiol Clin Pharm... A randomized study to compare palonosetron with ondansetron for prevention of postoperative nausea and vomiting following middle ear surgeries.
2019 J Perianesth Nurs Pharmacogenetics of Postoperative Nausea and Vomiting.
2019 Sep Am J Physiol Gastrointest... Deoxycholic acid activates colonic afferent nerves via 5-HT3 receptor-dependent and -independent mechanisms.
2019 Front Physiol Stimulatory Effect of 5-Hydroxytryptamine (5-HT) on Rat Capsaicin-Sensitive Lung Vagal Sensory Neurons via Activation of 5-HT3 Receptors.
2019 Jun Digestion The Traditional Medicine Banhasasim-Tang Depolarizes Pacemaker Potentials of Cultured Interstitial Cells of Cajal through M3 Muscarinic and 5-HT3 Receptors in Murine Small Intestine.
2019 Exp Neurol Enhanced descending pain facilitation in acute traumatic brain injury.
2019 Front Pharmacol Cannabidiol Affects the Bezold-Jarisch Reflex iviai TRPV1 and 5-HT3 Receptors and Has Peripheral Sympathomimetic Effects in Spontaneously Hypertensive and Normotensive Rats.
2019 Metab Brain Dis Contribution of serotonergic and nitrergic pathways, as well as monoamine oxidase-a and Na+, K+-ATPase enzymes in antidepressant-like action of ((4-tert-butylcyclohexylidene) methyl) (4-methoxystyryl) sulfide (BMMS).
2019 Biomed Chromatogr Rapid structure identification of nineteen metabolites of ondansetron in human urine using LCMSn.
2019 Res Pharm Sci Anti-inflammatory effects of alosetron mediated through 5-HT3 receptors on experimental colitis.
2019 Yakugaku Zasshi [Clinical Pharmacology Research for Promoting Individualized Cancer Chemotherapy].
2019 Sep Int J Neuropsychopharmacol Tropisetron Facilitates Footshock Suppression of Compulsive Cocaine Seeking.
2019 Support Care Cancer Evolution of antiemetic studies for radiation-induced nausea and vomiting within an outpatient palliative radiotherapy clinic.
2019 Cancer Chemother Pharmacol Olanzapine-containing antiemetic therapy for the prevention of carboplatin-induced nausea and vomiting.
2019 J Psychiatr Res Depression- and anxiogenic-like behaviors induced by lipopolysaccharide in mice are reversed by a selenium-containing indolyl compound: Behavioral, neurochemical and computational insights involving the serotonergic system.
2019 Beilstein J Org Chem Azologization of serotonin 5-HT3 receptor antagonists.
2019 Phytomedicine Yokukansan-induced reduction of ethanol preference is associated with antagonism of 5-HT3 receptors.
2019 Cogn Neurodyn L-menthol exhibits antidepressive-like effects mediated by the modification of 5-HTergic, GABAergic and DAergic systems.
2019 Mar Int J Mol Sci 5-HT3 Antagonist Ondansetron Increases apoE Secretion by Modulating the LXR-ABCA1 Pathway.
2019 Pediatr Blood Cancer Pharmacokineticspharmacodynamics, safety, and tolerability of fosaprepitant for the prevention of chemotherapy-induced nausea and vomiting in pediatric cancer patients.
2019 J Psychiatr Res Adjunctive ondansetron for schizophrenia: A systematic review and meta-analysis of randomized controlled trials.
2019 Psychopharmacology (Berl) Multi-modal antidepressant-like action of 6- and 7-chloro-2-aminodihydroquinazolines in the mouse tail suspension test.
2019 Biomed Pharmacother Potential roles of 5-HT3 receptor (5-HT3R) antagonists in modulating the effects of nicotine.
2019 Jan BMJ Open Study protocol for an open-label, single-arm, multicentre phase II trial to evaluate the efficacy and safety of combined triplet therapy and olanzapine for prevention of carboplatin-induced nausea and vomiting in gynaecological cancer patients.
2019 Support Care Cancer One shot NEPA plus dexamethasone to prevent multiple-day chemotherapy in sarcoma patients.
2019 Hypertens Res Hypertension exhibits 5-HT4 receptor as a modulator of sympathetic neurotransmission in the rat mesenteric vasculature.
2019 Jan Cancer Nurs Recent Advances in Antiemetics: New Formulations of 5-HT3 Receptor Antagonists in Adults.
2019 Apr Neurosci Lett Validation of the xylazineketamine anesthesia test as a predictor of the emetic potential of pharmacological compounds in rats.
2019 Mar Eur J Pharmacol β2-Microglobulin, interleukin-31, and arachidonic acid metabolites (leukotriene B4 and thromboxane A2) are involved in chronic renal failure-associated itch-associated responses in mice.
2019 IBRO Rep Anti-dyskinetic efficacy of 5-HT3 receptor antagonist in the hemi-parkinsonian rat model.
2019 Exp Dermatol Tropisetron via α7 nicotinic acetylcholine receptor presses tumor necrosis factor-α-mediated cell responses of human keratinocytes.
2019 Psychopharmacology (Berl) Anti-inflammatory and antinociceptive activities of glucagon-like peptides: evaluation of their actions on serotonergic, nitrergic, and opioidergic systems.
2019 J Neurochem Rostral ventromedial medulla-mediated descending facilitation following P2X7 receptor activation is involved in the development of chronic post-operative pain.
2018 Dec JAMA Association of Maternal First-Trimester Ondansetron Use With Cardiac Malformations and Oral Clefts in Offspring.
2018 J Pharm Health Care Sci Economic analysis of palonosetron versus granisetron in the standard triplet regimen for preventing chemotherapy-induced nausea and vomiting in patients receiving highly emetogenic chemotherapy in Japan (TRIPLE phase III trial).
2019 Biomed Pharmacother Tropisetron inhibits sepsis by repressing hyper-inflammation and regulating the cardiac action potential in rat models.
2019 Hepatology Intestinal Microbiota Mediates the Susceptibility to Polymicrobial Sepsis-Induced Liver Injury by Granisetron Generation in Mice.
2019 Jan Biochem Biophys Res Commun SR 57227A is a partial agonistpartial antagonist of 5-HT3 receptor and inhibits sequent 5-HT- or SR 57227A-induced 5-HT3 receptor current.
2019 Future Oncol Hydration requirements in patients receiving highly emetogenic chemotherapy.
2018 Jun Pharmacoeconomic Review R...
2019 Expert Opin Drug Discov Vortioxetine: a novel antidepressant for the treatment of major depressive disorder.
2018 Nov Mol Brain 5-HTR2A and 5-HTR3A but not 5-HTR1A antagonism impairs the cross-modal reactivation of deprived visual cortex in adulthood.
2019 Mar ACS Chem Neurosci "Methylene Bridge" to 5-HT3 Receptor Antagonists: Conformationally Constrained Phenylguanidines.