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Recent literature: 5-HT3 receptor antagonist
Date Journal Article title
2019 Int Rev Neurobiol Neuroprotective effects of 5-HT3 receptor antagonist ondansetron on morphine withdrawal induced brain edema formation, blood-brain barrier dysfunction, neuronal injuries, glial activation and heat shock protein upregulation in the brain.
2019 Aliment Pharmacol Ther Abnormalities of mucosal serotonin metabolism and 5-HT3 receptor unit 3C polymorphism in irritable bowel syndrome with diarrhoea predict responsiveness to ondansetron.
2019 Jul J Biochem Mol Toxicol Ondansetron enhanced diclofenac-induced nephrotoxicity in mice.
2019 Jul J Pharm Biomed Anal Highly sensitive HPLC-MSMS assay for the quantitation of ondansetron in rat plasma and rat brain tissue homogenate following administration of a very low cutaneous dose.
2019 Oct Eur J Pharmacol Mirtazapine increases glial cell line-derived neurotrophic factor production through lysophosphatidic acid 1 receptor-mediated extracellular signal-regulated kinase signaling in astrocytes.
2019 J Anaesthesiol Clin Pharm... A randomized study to compare palonosetron with ondansetron for prevention of postoperative nausea and vomiting following middle ear surgeries.
2019 Jun J Perianesth Nurs Pharmacogenetics of Postoperative Nausea and Vomiting.
2019 Front Physiol Stimulatory Effect of 5-Hydroxytryptamine (5-HT) on Rat Capsaicin-Sensitive Lung Vagal Sensory Neurons via Activation of 5-HT3 Receptors.
2019 Jun Digestion The Traditional Medicine Banhasasim-Tang Depolarizes Pacemaker Potentials of Cultured Interstitial Cells of Cajal through M3 Muscarinic and 5-HT3 Receptors in Murine Small Intestine.
2019 Exp Neurol Enhanced descending pain facilitation in acute traumatic brain injury.
2019 Front Pharmacol Cannabidiol Affects the Bezold-Jarisch Reflex iviai TRPV1 and 5-HT3 Receptors and Has Peripheral Sympathomimetic Effects in Spontaneously Hypertensive and Normotensive Rats.
2019 Jun Metab Brain Dis Contribution of serotonergic and nitrergic pathways, as well as monoamine oxidase-a and Na+, K+-ATPase enzymes in antidepressant-like action of ((4-tert-butylcyclohexylidene) methyl) (4-methoxystyryl) sulfide (BMMS).
2019 Jun Biomed Chromatogr Rapid structure identification of nineteen metabolites of ondansetron in human urine using LCMSn.
2019 Res Pharm Sci Anti-inflammatory effects of alosetron mediated through 5-HT3 receptors on experimental colitis.
2019 Yakugaku Zasshi [Clinical Pharmacology Research for Promoting Individualized Cancer Chemotherapy].
2019 May Int J Neuropsychopharmacol Tropisetron facilitates footshock pression of compulsive cocaine seeking.
2019 Support Care Cancer Evolution of antiemetic studies for radiation-induced nausea and vomiting within an outpatient palliative radiotherapy clinic.
2019 Cancer Chemother Pharmacol Olanzapine-containing antiemetic therapy for the prevention of carboplatin-induced nausea and vomiting.
2019 J Psychiatr Res Depression- and anxiogenic-like behaviors induced by lipopolysaccharide in mice are reversed by a selenium-containing indolyl compound: Behavioral, neurochemical and computational insights involving the serotonergic system.
2019 Beilstein J Org Chem Azologization of serotonin 5-HT3 receptor antagonists.
2019 Phytomedicine Yokukansan-induced reduction of ethanol preference is associated with antagonism of 5-HT3 receptors.
2019 Cogn Neurodyn L-menthol exhibits antidepressive-like effects mediated by the modification of 5-HTergic, GABAergic and DAergic systems.
2019 Mar Int J Mol Sci 5-HT3 Antagonist Ondansetron Increases apoE Secretion by Modulating the LXR-ABCA1 Pathway.
2019 Pediatr Blood Cancer Pharmacokineticspharmacodynamics, safety, and tolerability of fosaprepitant for the prevention of chemotherapy-induced nausea and vomiting in pediatric cancer patients.
2019 J Psychiatr Res Adjunctive ondansetron for schizophrenia: A systematic review and meta-analysis of randomized controlled trials.
2019 Psychopharmacology (Berl) Multi-modal antidepressant-like action of 6- and 7-chloro-2-aminodihydroquinazolines in the mouse tail suspension test.
2019 Biomed Pharmacother Potential roles of 5-HT3 receptor (5-HT3R) antagonists in modulating the effects of nicotine.
2019 Support Care Cancer One shot NEPA plus dexamethasone to prevent multiple-day chemotherapy in sarcoma patients.
2019 Hypertens Res Hypertension exhibits 5-HT4 receptor as a modulator of sympathetic neurotransmission in the rat mesenteric vasculature.
2019 Jan Cancer Nurs Recent Advances in Antiemetics: New Formulations of 5-HT3 Receptor Antagonists in Adults.
2019 Apr Neurosci Lett Validation of the xylazineketamine anesthesia test as a predictor of the emetic potential of pharmacological compounds in rats.
2019 Mar Eur J Pharmacol β2-Microglobulin, interleukin-31, and arachidonic acid metabolites (leukotriene B4 and thromboxane A2) are involved in chronic renal failure-associated itch-associated responses in mice.
2019 IBRO Rep Anti-dyskinetic efficacy of 5-HT3 receptor antagonist in the hemi-parkinsonian rat model.
2019 Exp Dermatol Tropisetron via α7 nicotinic acetylcholine receptor presses tumor necrosis factor-α-mediated cell responses of human keratinocytes.
2019 Psychopharmacology (Berl) Anti-inflammatory and antinociceptive activities of glucagon-like peptides: evaluation of their actions on serotonergic, nitrergic, and opioidergic systems.
2019 J Neurochem Rostral ventromedial medulla-mediated descending facilitation following P2X7 receptor activation is involved in the development of chronic post-operative pain.
2018 Dec JAMA Association of Maternal First-Trimester Ondansetron Use With Cardiac Malformations and Oral Clefts in Offspring.
2018 J Pharm Health Care Sci Economic analysis of palonosetron versus granisetron in the standard triplet regimen for preventing chemotherapy-induced nausea and vomiting in patients receiving highly emetogenic chemotherapy in Japan (TRIPLE phase III trial).
2019 Biomed Pharmacother Tropisetron inhibits sepsis by repressing hyper-inflammation and regulating the cardiac action potential in rat models.
2019 Hepatology Intestinal Microbiota Mediates the Susceptibility to Polymicrobial Sepsis-Induced Liver Injury by Granisetron Generation in Mice.
2019 Jan Biochem Biophys Res Commun SR 57227A is a partial agonistpartial antagonist of 5-HT3 receptor and inhibits sequent 5-HT- or SR 57227A-induced 5-HT3 receptor current.
2019 Future Oncol Hydration requirements in patients receiving highly emetogenic chemotherapy.
2018 Jun Pharmacoeconomic Review R...
2019 Expert Opin Drug Discov Vortioxetine: a novel antidepressant for the treatment of major depressive disorder.
2018 Nov Mol Brain 5-HTR2A and 5-HTR3A but not 5-HTR1A antagonism impairs the cross-modal reactivation of deprived visual cortex in adulthood.
2019 Mar ACS Chem Neurosci "Methylene Bridge" to 5-HT3 Receptor Antagonists: Conformationally Constrained Phenylguanidines.
2019 Jan Am J Physiol Gastrointest... 5-HT3 receptor signaling in serotonin transporter-knockout rats: a female sex-specific animal model of visceral hypersensitivity.
2019 Food Chem Toxicol Role of neurotransmitters 5-hydroxytryptamine and stance P in anorexia induction following oral exposure to the trichothecene T-2 toxin.
2019 Feb Brain Res Breathing stimulation mediated by 5-HT1A and 5-HT3 receptors within the preBötzinger complex of the adult rabbit.
2018 Neuropharmacology The 5-HT3 receptor antagonist ondansetron potentiates the effects of the acetylcholinesterase inhibitor donepezil on neuronal network oscillations in the rat dorsal hippocampus.
2018 Neurobiol Stress Anti-stress neuropharmacological mechanisms and targets for addiction treatment: A translational framework.
2018 Radiat Res Involvement of the Hypothalamic Glutamatergic System in the Development of Radiation-Induced Pica in Rats.
2019 Handb Exp Pharmacol Other Antidepressants.
2018 Sep Med Oncol Prophylactic aprepitant is better than salvage for carboplatin-based chemotherapy: a propensity score-matched analysis.
2018 Ann Palliat Med Management of radiation-induced nausea and vomiting with palonosetron in patients with pre-existing emesis: a pilot study.
2019 Oncologist Oral Ondansetron Offers Effective Antidiarrheal Activity for Carcinoid Syndrome Refractory to Somatostatin Analogs.
2019 Jan ACS Chem Neurosci Mapping the Orthosteric Binding Site of the Human 5-HT3 Receptor Using Photo-cross-linking Antagonists.
2018 Oct Eur J Pharmacol The novel peripherally active cannabinoid type 1 and serotonin type 3 receptor agonist AM9405 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome.
2019 Neuropsychopharmacology High-dose ondansetron reduces activation of interoceptive and sensorimotor brain regions.
2019 Support Care Cancer Cost-effectiveness analysis of olanzapine-containing antiemetic therapy for managing highly emetogenic chemotherapy in Southeast Asia: a multinational study.
2018 Sep J Chromatogr B Analyt Tec... Identification of novel ondansetron metabolites using LCMSn and NMR.
2018 Medicine (Baltimore) Continuous administration of ramosetron with patient-controlled analgesia after laparoscopic distal gastrectomy does not delay postoperative bowel function recovery: A prospective, randomized, double-blinded study.
2018 eNeuro Nausea-Induced 5-HT Release in the Interoceptive Insular Cortex and Regulation by Monoacylglycerol Lipase (MAGL) Inhibition and Cannabidiol.
2018 Neurogastroenterol Motil Translocator protein 18kDa antagonist ameliorates stress-induced stool abnormality and abdominal pain in rodent stress models.
2018 Brain Res Bull Colitis-induced alterations in response properties of visceral nociceptive neurons in the rat caudal medulla oblongata and their modulation by 5-HT3 receptor blockade.
2018 J Clin Pharm Ther Agomelatine, a novel therapeutic option for the management of irritable bowel syndrome.
2018 Comp Biochem Physiol A Mo... Isolated adult turtle brainstems exhibit central hypoxic chemosensitivity.
2018 Biomed Res Int Nephrotoxicity Evaluation on Cisplatin Combined with 5-HT3 Receptor Antagonists: A Retrospective Study.
2018 Jul Sci Rep New βN-octadecanoyl-5-hydroxytryptamide: antinociceptive effect and possible mechanism of action in mice.
2018 Medicine (Baltimore) A phase 2 study of fosaprepitant combined with high-dose dexamethasone for Japanese cancer patients receiving highly emetogenic chemotherapy.
2018 Support Care Cancer Should palonosetron be a preferred 5-HT3 receptor antagonist for chemotherapy-induced nausea and vomiting? An updated systematic review and meta-analysis.
2018 J Pediatr Hematol Oncol Evaluation of the Use of Fosaprepitant for the Prevention of Chemotherapy-induced Nausea and Vomiting in Pediatric Patients.
2018 Fitoterapia Antidepressant potential of novel flavonoids derivatives from sweet violet (Viola odorata L): Pharmacological, biochemical and computational evidences for possible involvement of serotonergic mechanism.
2018 Apr Phytomedicine Yokukansan contains compounds that antagonize the 5-HT3 receptor.
2018 Curr Opin Oncol The latest consensus on antiemetics.