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Recent literature: Estrogen receptor antagonist
Date Journal Article title
2019 Apr FASEB J Mammary adipose stromal cells derived from obese women reduce sensitivity to the aromatase inhibitor anastrazole in an organotypic breast model.
2019 Apr Breast Cancer Res Treat Propagation of functional estrogen receptor positive normal human breast cells in 3D cultures.
2019 Apr J Neurosci Estrogen-Dependent Functional Spine Dynamics in Neocortical Pyramidal Neurons of the Mouse.
2019 Apr Cancers (Basel) Combined Targeting of Estrogen Receptor Alpha and XPO1 Prevent Akt Activation, Remodel Metabolic Pathways and Induce Autophagy to Overcome Tamoxifen Resistance.
2019 Apr Horm Behav Plasma membrane G protein-coupled estrogen receptor 1 (GPER) mediates rapid estradiol facilitation of sexual receptivity through the orphanin-FQ-ORL-1 system in estradiol primed female rats.
2019 Apr Mol Cell Endocrinol Estrogen interacts with glucocorticoids in the regulation of lipocalin 2 expression in human adipose tissue. Reciprocal roles of estrogen receptor α and β in insulin resistance?
2019 Apr Cancer Res Estrogen Receptor Covalent Antagonists: The Best Is Yet to Come.
2019 Mar Oncol Res E2-induced activation of the NLRP3 inflammasome triggers pyroptosis and inhibits autophagy in HCC cells.
2019 Mar Toxicology Estimation of competitive antagonist affinity by the Schild method and from functional inhibition curves using a novel form of the Gaddum equation.
2019 Mar J Neuroendocrinol Age-dependent regulation by androgens of gene expression in the anterior hypothalamus and stress-induced release of adrenal hormones in adolescent and adult male rats.
2019 Jan Domest Anim Endocrinol Peripheral administration of κ-opioid receptor antagonist stimulates gonadotropin-releasing hormone pulse generator activity in ovariectomized, estrogen-treated female goats.
2019 Jul Ecotoxicol Environ Saf A comparison of endocrine disruption potential of nonylphenol ethoxylate, vanillin ethoxylate, 4-n-nonylphenol and vanillin in vitro.
2019 Climacteric Beyond estrogen: advances in tissue selective estrogen complexes and selective estrogen receptor modulators.
2019 J Neuroendocrinol Oestradiol acts through its beta receptor to increase vasopressin neuronal activation and secretion induced by dehydration.
2019 Apr Biochem Biophys Res Commun Estradiol stimulates cell proliferation via classic estrogen receptor-alpha and G protein-coupled estrogen receptor-1 in human renal tubular epithelial cell primary cultures.
2019 Biochim Biophys Acta Mol ... Lactate dehydrogenase A regulates autophagy and tamoxifen resistance in breast cancer.
2019 Mol Med Rep Estrogen receptor β presses inflammation and the progression of prostate cancer.
2019 Apr Mol Cell Endocrinol Maternal exposure to imazalil disrupts the endocrine system in F1 generation mice.
2019 Diabetes Fasting-Induced Transcription Factors Repress Vitamin D Bioactivation, a Mechanism for Vitamin D Deficiency in Diabetes.
2019 Feb Environ Pollut Computational insights on agonist and antagonist mechanisms of estrogen receptor α induced by bisphenol A analogues.
2019 Mar Toxicol Sci Tetrabromobisphenol A (TBBPA) Alters ABC Transport at the Blood-Brain Barrier.
2019 Biol Pharm Bull Novel Ridaifen-B Structure Analog Induces Apoptosis and Autophagy Depending on Pyrrolidine Side Chain.
2019 Neural Regen Res GPER agonist G1 presses neuronal apoptosis mediated by endoplasmic reticulum stress after cerebral ischemiareperfusion injury.
2019 Jun Behav Brain Res Alteration in oxytocin levels induced by early social environment affects maternal behavior and estrogen receptor alpha in mandarin voles (Microtus mandarinus).
2019 Steroids Design and synthesis of fluorescently labeled steroidal antiestrogens.
2019 Jul Brain Res G protein-coupled estrogen receptor 1 negatively regulates the proliferation of mouse-derived neural stemprogenitor cells via extracellular signal-regulated kinase pathway.
2019 Apr Biochem Biophys Res Commun Estrogen receptors participate in carcinogenesis signaling pathways by directly regulating NOD-like receptors.
2019 Feb Toxicol Sci Molecular Mechanisms of Polybrominated Diphenyl Ethers (BDE-47, -100 and -153) in Human Breast Cancer Cells and Patient-Derived Xenografts.
2019 Feb J Exp Clin Cancer Res Aberrant fatty acid profile and FFAR4 signaling confer endocrine resistance in breast cancer.
2019 Front Pharmacol Repeated Administration of Norbinaltorphimine Produces Cumulative Kappa Opioid Receptor Inactivation.
2019 Exp Ther Med Oestrogen inhibits PTPRO to prevent the apoptosis of renal podocytes.
2019 Feb Immunol Cell Biol Macrophage ERα promoted invasion of endometrial cancer cell by mTORKIF5B-mediated epithelial to mesenchymal transition.
2019 Front Pharmacol iCalculus Bovis Sativusi Improves Bile Acid Homeostasis via Farnesoid X Receptor-Mediated Signaling in Rats With Estrogen-Induced Cholestasis.
2019 eNeuro Estradiol-Induced Potentiation of Dopamine Release in Dorsal Striatum Following Amphetamine Administration Requires Estradiol Receptors and mGlu5.
2018 Apr Reproduction Notch activity mediates oestrogen-induced stromal cell invasion in endometriosis.
2019 Feb Toxicol In Vitro Assessment of human estrogen receptor agonisticantagonistic effects of veterinary drugs used for livestock and farmed fish by OECD in vitro stably transfected transcriptional activation assays.
2019 Feb Curr Treat Options Oncol Management of Nonmetastatic Castration-Resistant Prostate Cancer: Recent Advances and Future Direction.
2019 May Ecotoxicol Environ Saf Estrogen receptor β plays a protective role in zearalenone-induced oxidative stress in normal prostate epithelial cells.
2019 Evid Based Complement Alt... Adenosine Attenuates LPS-Induced Cardiac Dysfunction by Inhibition of Mitochondrial Function via the ER Pathway.
2019 Apr Mol Cell Endocrinol Rapid effect of bisphenol A on glutamate-induced Ca2+ influx in hippocampal neurons of rats.
2019 Jan Clin Cancer Res Cell-Proliferation Imaging for Monitoring Response to CDK46 Inhibition Combined with Endocrine-Therapy in Breast Cancer: Comparison of [18F]FLT and [18F]ISO-1 PETCT.
2019 Toxicol In Vitro Arsenic induces gender difference of estrogen receptor in AECII cells from ICR fetal mice.
2019 Toxicol In Vitro Evidences for involvement of estrogen receptor induced ERK12 activation in ovarian cancer cell proliferation by Cadmium Chloride.
2019 Mutat Res Cytotoxic and genotoxic effects of environmental relevant concentrations of bisphenol A and interactions with doxorubicin.
2019 Toxicol In Vitro Involvement of estrogen receptor and GPER in bisphenol A induced proliferation of vascular smooth muscle cells.
2019 Expert Opin Investig Drugs Oral investigational drugs currently in phase I or phase II for the amelioration of menopausal symptoms.
2018 Neuro Endocrinol Lett Selected bisphenols and phthalates screened for estrogen and androgen disruption by in silico and in vitro methods.
2019 Int J Biol Sci G Protein-Coupled Estrogen Receptor 1 Inhibits Angiotensin II-Induced Cardiomyocyte Hypertrophy via the Regulation of PI3K-Akt-mTOR Signalling and Autophagy.
2019 PLoS One Comparison of the binding of the gastrin-releasing peptide receptor (GRP-R) antagonist 68Ga-RM2 and 18F-FDG in breast cancer samples.
2019 Feb J Med Chem Tricyclic Indazoles-A Novel Class of Selective Estrogen Receptor Degrader Antagonists.
2019 Oncol Rep Anticancer effects of methotrexate in combination with α‑tocopherol and α‑tocopherol succinate on triple‑negative breast cancer.
2018 J Environ Sci Health C En... Machine learning models for predicting endocrine disruption potential of environmental chemicals.
2019 Chemosphere Evaluation of endocrine activities of ellagic acid and urolithins using reporter gene assays.
2019 Jan Metabolites Palbociclib and Fulvestrant Act in Synergy to Modulate Central Carbon Metabolism in Breast Cancer Cells.
2019 Jan Reprod Biol Endocrinol Profile of melatonin and its receptors and synthesizing enzymes in cumulus-oocyte complexes of the developing sheep antral follicle-a potential estradiol-mediated mechanism.
2019 Feb Endocrinology Phosphorylated Progesterone Receptor Isoforms Mediate Opposing Stem Cell and Proliferative Breast Cancer Cell Fates.
2019 Mar Arch Biochem Biophys 17-β-estradiol enhances neutrophil extracellular trap formation by interaction with estrogen membrane receptor.
2019 Feb J Clin Oncol Neoadjuvant Degarelix Versus Triptorelin in Premenopausal Patients Who Receive Letrozole for Locally Advanced Endocrine-Responsive Breast Cancer: A Randomized Phase II Trial.
2019 J Neurochem G protein-coupled estrogen receptor activates cell type-specific signaling pathways in cortical cultures: relevance to the selective loss of astrocytes.
2018 Dec Exp Mol Med Estrogen modulates serotonin effects on vasoconstriction through Src inhibition.
2019 Feb Endocr Relat Cancer Non-canonical AR activity facilitates endocrine resistance in breast cancer.
2019 Jan Life Sci MicroRNA-22 inhibits proliferation, invasion and metastasis of breast cancer cells through targeting truncated neurokinin-1 receptor and ERα.
2018 Dec Aging (Albany NY) BCAR4 activates GLI2 signaling in prostate cancer to contribute to castration resistance.
2018 Nov J Endocrinol Invest Cadmium exposure alters steroid receptors and proinflammatory cytokine levels in endothelial cells in vitro: a potential mechanism of endocrine disruptor atherogenic effect.
2019 J Environ Sci (China) Molecular mechanism of endocrine-disruptive effects induced by Bisphenol A: The role of transmembrane G-protein estrogen receptor 1 and integrin αvβ3.
2019 Horm Behav Anorexigenic effects of estradiol in the medial preoptic area occur through membrane-associated estrogen receptors and metabotropic glutamate receptors.
2019 Steroids Equilin displays similar endothelium-independent vasodilator potential to 17β-estradiol regardless of lower potential to inhibit calcium entry.
2019 Fish Shellfish Immunol Interruption of immune responses in primary macrophages exposed to nonylphenol provides insights into the role of ER and NF-KB in immunotoxicity of Persian sturgeon.
2019 Jan Life Sci Involvement of inducible nitric oxide synthase and estrogen receptor ESR2 (ERβ) in the vascular dysfunction in female type 1 diabetic rats.
2018 Nov Endocr Relat Cancer Lymphangiogenesis contribute to sex differences in lung cancer through ERalpha signalling.
2019 J Steroid Biochem Mol Biol G protein-coupled receptor 30 mediates meiosis resumption and gap junction communications downregulation in goat cumulus-oocyte complexes by 17β-estradiol.
2019 J Assist Reprod Genet Could polymorphisms of some hormonal receptor genes, involved in folliculogenesis help in predicting patient response to controlled ovarian stimulation?
2018 J Periodontal Implant Sci Estrogen reinforces barrier formation and protects against tumor necrosis factor alpha-induced barrier dysfunction in oral epithelial cells.
2018 J Cancer Oestrogen Inhibits VEGF Expression And Angiogenesis In Triple-Negative Breast Cancer By Activating GPER-1.
2018 Dec ACS Chem Biol Antagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain.