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Recent literature: Estrogen receptor antagonist
Date Journal Article title
2019 Feb Reproduction Notch activity mediates oestrogen-induced stromal cell invasion in endometriosis.
2019 Feb Toxicol In Vitro Assessment of human estrogen receptor agonisticantagonistic effects of veterinary drugs used for livestock and farmed fish by OECD in vitro stably transfected transcriptional activation assays.
2019 Feb Curr Treat Options Oncol Management of Nonmetastatic Castration-Resistant Prostate Cancer: Recent Advances and Future Direction.
2019 Feb Ecotoxicol Environ Saf Estrogen receptor β plays a protective role in zearalenone-induced oxidative stress in normal prostate epithelial cells.
2019 Evid Based Complement Alt... Adenosine Attenuates LPS-Induced Cardiac Dysfunction by Inhibition of Mitochondrial Function via the ER Pathway.
2019 Jan Mol Cell Endocrinol Rapid effect of bisphenol A on glutamate-induced Ca2+ influx in hippocampal neurons of rats.
2019 Jan Clin Cancer Res Cell-proliferation imaging for monitoring response to CDK46 inhibition combined with endocrine-therapy in breast cancer: Comparison of [18F]FLT and [18F]ISO-1 PETCT.
2019 Jan Toxicol In Vitro Arsenic induces gender difference of estrogen receptor in AECII cells from ICR fetal mice.
2019 Jan Toxicol In Vitro Evidences for involvement of estrogen receptor induced ERK12 activation in ovarian cancer cell proliferation by Cadmium Chloride.
2019 Mutat Res Cytotoxic and genotoxic effects of environmental relevant concentrations of bisphenol A and interactions with doxorubicin.
2019 Jan Toxicol In Vitro Involvement of estrogen receptor and GPER in bisphenol A induced proliferation of vascular smooth muscle cells.
2019 Expert Opin Investig Drugs Oral investigational drugs currently in phase I or phase II for the amelioration of menopausal symptoms.
2018 Dec Neuro Endocrinol Lett Selected bisphenols and phthalates screened for estrogen and androgen disruption by in silico and in vitro methods.
2019 Int J Biol Sci G Protein-Coupled Estrogen Receptor 1 Inhibits Angiotensin II-Induced Cardiomyocyte Hypertrophy via the Regulation of PI3K-Akt-mTOR Signalling and Autophagy.
2019 PLoS One Comparison of the binding of the gastrin-releasing peptide receptor (GRP-R) antagonist 68Ga-RM2 and 18F-FDG in breast cancer samples.
2019 Jan J Med Chem Tricyclic Indazoles-A Novel Class of Selective Estrogen Receptor Degrader Antagonists.
2019 Oncol Rep Anticancer effects of methotrexate in combination with α‑tocopherol and α‑tocopherol succinate on triple‑negative breast cancer.
2019 Jan J Environ Sci Health C En... Machine learning models for predicting endocrine disruption potential of environmental chemicals.
2019 Chemosphere Evaluation of endocrine activities of ellagic acid and urolithins using reporter gene assays.
2019 Jan Metabolites Palbociclib and Fulvestrant Act in Synergy to Modulate Central Carbon Metabolism in Breast Cancer Cells.
2019 Jan Reprod Biol Endocrinol Profile of melatonin and its receptors and synthesizing enzymes in cumulus-oocyte complexes of the developing sheep antral follicle-a potential estradiol-mediated mechanism.
2019 Feb Endocrinology Phosphorylated Progesterone Receptor Isoforms Mediate Opposing Stem Cell and Proliferative Breast Cancer Cell Fates.
2019 Mar Arch Biochem Biophys 17-β-estradiol enhances neutrophil extracellular trap formation by interaction with estrogen membrane receptor.
2019 Feb J Clin Oncol Neoadjuvant Degarelix Versus Triptorelin in Premenopausal Patients Who Receive Letrozole for Locally Advanced Endocrine-Responsive Breast Cancer: A Randomized Phase II Trial.
2018 Dec J Neurochem G protein-coupled estrogen receptor activates cell type-specific signaling pathways in cortical cultures: relevance to the selective loss of astrocytes.
2018 Dec Exp Mol Med Estrogen modulates serotonin effects on vasoconstriction through Src inhibition.
2019 Feb Endocr Relat Cancer Non-canonical AR activity facilitates endocrine resistance in breast cancer.
2019 Jan Life Sci MicroRNA-22 inhibits proliferation, invasion and metastasis of breast cancer cells through targeting truncated neurokinin-1 receptor and ERα.
2018 Dec Aging (Albany NY) BCAR4 activates GLI2 signaling in prostate cancer to contribute to castration resistance.
2018 Nov J Endocrinol Invest Cadmium exposure alters steroid receptors and proinflammatory cytokine levels in endothelial cells in vitro: a potential mechanism of endocrine disruptor atherogenic effect.
2019 J Environ Sci (China) Molecular mechanism of endocrine-disruptive effects induced by Bisphenol A: The role of transmembrane G-protein estrogen receptor 1 and integrin αvβ3.
2019 Horm Behav Anorexigenic effects of estradiol in the medial preoptic area occur through membrane-associated estrogen receptors and metabotropic glutamate receptors.
2019 Steroids Equilin displays similar endothelium-independent vasodilator potential to 17β-estradiol regardless of lower potential to inhibit calcium entry.
2019 Fish Shellfish Immunol Interruption of immune responses in primary macrophages exposed to nonylphenol provides insights into the role of ER and NF-KB in immunotoxicity of Persian sturgeon.
2019 Jan Life Sci Involvement of inducible nitric oxide synthase and estrogen receptor ESR2 (ERβ) in the vascular dysfunction in female type 1 diabetic rats.
2018 Nov Endocr Relat Cancer Lymphangiogenesis contribute to sex differences in lung cancer through ERalpha signalling.
2019 J Steroid Biochem Mol Biol G protein-coupled receptor 30 mediates meiosis resumption and gap junction communications downregulation in goat cumulus-oocyte complexes by 17β-estradiol.
2018 J Periodontal Implant Sci Estrogen reinforces barrier formation and protects against tumor necrosis factor alpha-induced barrier dysfunction in oral epithelial cells.
2018 J Cancer Oestrogen Inhibits VEGF Expression And Angiogenesis In Triple-Negative Breast Cancer By Activating GPER-1.
2018 Nov ACS Chem Biol Antagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain.
2018 Oct J Endocrinol Role of GPER in the anterior pituitary gland focusing on lactotroph function.
2018 Neuropeptides Sex differences in forebrain estrogen receptor regulation of hypoglycemic patterns of counter-regulatory hormone secretion and ventromedial hypothalamic nucleus glucoregulatory neurotransmitter and astrocyte glycogen metabolic enzyme expression.
2019 Toxicol Lett In vitro bioassay investigations of suspected obesogen monosodium glutamate at the level of nuclear receptor binding and steroidogenesis.
2019 Jan Neurosci Lett 17β-Estradiol attenuates the influence of chronic activated microglia on SH-SY5Y cell proliferation via canonical WNT signaling pathway.
2019 Jan Gen Comp Endocrinol Telocytes are localized to testis of the bank vole (Myodes glareolus) and are affected by lighting conditions and G-coupled membrane estrogen receptor (GPER) signaling.
2018 Nov J Cell Biochem Epigallocatechin-3-gallate regulates mitofusin 2 expression through the peroxisome proliferator-activated receptor-γ coactivator-1α and estrogen-related receptor-α pathway.
2019 Cancer Chemother Pharmacol Nonclinical pharmacokinetics and in vitro metabolism of H3B-6545, a novel selective ERα covalent antagonist (SERCA).
2018 Oct Biol Sex Differ Estrogen rescues heart failure through estrogen receptor Beta activation.
2019 Phytother Res Radix Paeoniae Alba increases serum estrogen level and up-regulates estrogen receptor expression in uterus and vagina of immatureovariectomized mice.
2018 Dec Acta Biochim Biophys Sin ... 17β-estradiol promotes recovery after myocardial infarction by enhancing homing and angiogenic capacity of bone marrow-derived endothelial progenitor cells through ERα-SDF-1CXCR4 crosstalking.
2018 Oct Stress Disruptions in the reproductive system of female rats after prenatal lipopolysaccharide-induced immunological stress: role of sex steroids.
2019 Arch Virol An estrogen antagonist, cyclofenil, has anti-dengue-virus activity.
2018 Oct Korean J Intern Med 17β-Estradiol reduces inflammation and modulates antioxidant enzymes in colonic epithelial cells.
2018 Oct Reproduction Inhibition of TMEM16A impedes embryo implantation and decidualization in mice
2018 Oct J Cell Biochem IL-1 induces p62SQSTM1 and autophagy in ERα+ PR+ BCa cell lines concomitant with ERα and PR repression, conferring an ERα- PR- BCa-like phenotype.
2018 Oct J Cell Physiol Estradiol-17β stimulates H2 S biosynthesis by ER-dependent CBS and CSE transcription in uterine artery smooth muscle cells in vitro.
2018 J Lipid Res Sphingosine kinase 1 activation by estrogen receptor α36 contributes to tamoxifen resistance in breast cancer.
2018 Oct Molecules Isopsoralen Enhanced Osteogenesis by Targeting AhRERα.
2018 Exp Gerontol The involvement of estrogen receptors α and β in the in vitro effects of 17β-estradiol on secretory profile of peritoneal macrophages from naturally menopausal female and middle-aged male rats.
2018 Oct Biol Reprod E2β Stimulates Ovine Uterine Artery Endothelial Cell H2S Production in vitro by ER-dependent Upregulation of CBS and CTH Expression.
2018 Evid Based Complement Alt... Lepidiumuridine A: A New Natural Uridine Derivative as a Phytoestrogen Isolated from the Seeds of iLepidium apetalumi Willd.
2018 Onco Targets Ther Clinical benefit of fulvestrant monotherapy in the multimodal treatment of hormone receptor and HER2 positive advanced breast cancer: a case series.
2018 Sep J Cheminform Exploring non-linear distance metrics in the structure-activity space: QSAR models for human estrogen receptor.
2018 Int J Oncol Tamoxifen inhibits the proliferation of non‑melanoma skin cancer cells by increasing intracellular calcium concentration.
2018 Mol Cancer Ther Targeting Peroxisome Proliferator-Activated Receptor γ to Increase Estrogen-Induced Apoptosis in Estrogen-Deprived Breast Cancer Cells.
2018 Oct J Chem Theory Comput Protein Conformational Transitions from All-Atom Adaptively Biased Path Optimization.
2018 J Pharmacol Exp Ther Sex Differences in the Pharmacokinetics of Low-dose Ketamine in Plasma and Brain of Male and Female Rats.
2018 Sep Biochem Biophys Res Commun The protective effects of estrogen on hepatic ischemia-reperfusion injury in rats by downregulating the Ang IIAT1R pathway.
2019 Future Oncol Treatment satisfaction in women receiving palbociclib combination therapies for advancedmetastatic breast cancer.
2018 Sep J Cell Biochem Bisphenol A stimulates steroidogenic acute regulatory protein expression via an unknown mechanism in adrenal cortical cells.
2018 Sep J Nat Prod Irilone from Red Clover ( Trifolium pratense) Potentiates Progesterone Signaling.
2019 J Appl Toxicol Effects of bisphenol A on gap junctions in HaCaT cells as mediated by the estrogen receptor pathway.
2018 Sep Protoplasma Telocytes in the mouse testicular interstitium: implications of G-protein-coupled estrogen receptor (GPER) and estrogen-related receptor (ERR) in the regulation of mouse testicular interstitial cells.
2018 Yakugaku Zasshi [Development of Protein Knockdown Technology as Emerging Drug Discovery Strategy].
2018 Mol Oncol Targeting newly identified ERβTGF-β1SMAD3 signals with the FDA-approved anti-estrogen Faslodex or an ERβ selective antagonist in renal cell carcinoma.