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Recent literature: Estrogen receptor antagonist
Date Journal Article title
2020 Jan Br J Pharmacol Overcoming Tamoxifen-Resistance in Estrogen Receptor Positive Breast Cancer Using the Novel Thiosemicarbazone Anti-Cancer Agent, DpC.
2020 Jan Curr Pharm Biotechnol Icariin stimulates hFOB 1.19 osteoblast proliferation and differentiation via OPGRANKL mediated by the estrogen receptor.
2020 Jan Fundam Clin Pharmacol GPER-mediated, estrogen-dependent visceral hypersensitivity in stressed rats is associated with mast cell tryptase and histamine expression.
2020 Jan FASEB J Corylin, a flavonoid derived from Psoralea Fructus, induces osteoblastic differentiation via estrogen and Wntβ-catenin signaling pathways.
2019 Sep - J Pharmacol Toxicol Methods H3B-6545, a selective estrogen receptor covalent antagonist, prevents bone loss in ovariectomized Sprague-Dawley rats.
2020 Jan J Biomol Struct Dyn Syringaresinol as a novel androgen receptor antagonist against wild and mutant androgen receptors for the treatment of castration-resistant prostate cancer: molecular docking, iin-vitroi and molecular dynamics study.
2020 Jan Neurotoxicol Teratol Bisphenol A (BPA) induces progesterone receptor expression in an estrogen receptor α-dependent manner in perinatal brain.
2019 Front Neurosci Activation of the G Protein-Coupled Estrogen Receptor Elicits Store Calcium Release and Phosphorylation of the Mu-Opioid Receptors in the Human Neuroblastoma SH-SY5Y Cells.
2020 Jan Anticancer Drugs Combination treatment of bicalutamide and curcumin has a strong therapeutic effect on androgen receptor-positive triple-negative breast cancers.
2019 Prev Nutr Food Sci Standardized Seed Extract of iQuisqualis indicai (HU-033) Attenuates Testosterone Propionate-Induced Benign Prostatic Hyperplasia iviai α1-Adrenergic Receptors and AndrogenEstrogen Signaling.
2020 Jan J Physiol Biochem The isoflavone genistein enhances osteoblastogenesis: signaling pathways involved.
2020 Jan Stress Expression of estrogen receptor alpha in response to stress and estrogen antagonist tamoxifen in the shell gland of iGallus gallus domesticusi: involvement of anti-oxidant system and estrogen.
2019 Dec Mol Cell Endocrinol Identification of a novel C-terminally truncated estrogen receptor α variant (ERαi34) with constitutive transactivation and estrogen receptor antagonist resistance.
2020 Feb Bioorg Med Chem Bisphenol AF: Halogen bonding effect is a major driving force for the dual ERα-agonist and ERβ-antagonist activities.
2019 Zhongguo Zhong Yao Za Zhi [Molecular mechanism of apoptosis of breast cancer SKBR-3 cells induced by cryptanshinone via G protein coupled estrogen receptor( GPER) mediated pathway].
2019 Front Cell Dev Biol Targeting Pin1 by All-Trans Retinoic Acid (ATRA) Overcomes Tamoxifen Resistance in Breast Cancer via Multifactorial Mechanisms.
2019 Dec Fish Physiol Biochem First evidence on protective effect of exogenous melatonin plementation against disruption of the estrogenic pathway in bone metabolism of killifish (Aphanius fasciatus).
2019 Dec Cells STK34 Expression Is Regulated in Uterine Endometrial Cells during the Estrous Cycle.
2020 Feb Physiol Behav Metabotropic glutamate receptor type 5 (mGlu5) is necessary for estradiol mitigation of light-induced anxiety behavior in female rats.
2019 Cell Mol Biol Lett Estrogen stimulates SREBP2 expression in hepatic cell lines via an estrogen response element in the SREBP2 promoter.
2019 Dec Proc Natl Acad Sci U S A FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer.
2019 Adv Appl Bioinform Chem Cytotoxicity Of Chalcone Of iEugeniai iaqueai Burm F. Leaves Against T47D Breast Cancer Cell Lines And Its Prediction As An Estrogen Receptor Antagonist Based On Pharmacophore-Molecular Dynamics Simulation.
2019 Front Neurosci Ginsenoside Rg1 Exerts Anti-inflammatory Effects via G Protein-Coupled Estrogen Receptor in Lipopolysaccharide-Induced Microglia Activation.
2019 Nov J Neurochem Donepezil-induced oligodendrocyte differentiation is mediated through estrogen receptors.
2019 Nov Adv Exp Med Biol Targeted Drug Delivery from Titanium Implants: A Review of Challenges and Approaches.
2019 Nov J Clin Endocrinol Metab Activation of β-catenin signaling and its cross talk with estrogen and histone deacetylases in human uterine fibroids.
2020 Biochem Pharmacol Regulation of beta adrenoceptor-mediated myocardial contraction and calcium dynamics by the G protein-coupled estrogen receptor 1.
2019 Dec Life Sci The protective role of estrogen and its receptors in gentamicin-induced acute kidney injury in rats.
2019 Nov Eur J Pharmacol Inhibitory effect of α1D1A antagonist 2-(1H-indol-3-yl)-N-[3-(4-(2-methoxyphenyl) piperazinyl) propyl] acetamide on estrogenandrogen-induced rat benign prostatic hyperplasia model in vivo.
2019 Oct Anticancer Agents Med Chem Coumarin- Fatty Acid Conjugates as Potential ERαAKT-1 Antagonists for ER Positive Breast Cancer.
2020 Mol Biol Rep LPS impairs steroidogenesis and ROS metabolism and induces PPAR transcriptional activity to disturb estrogenandrogen receptor expression in testicular cells.
2019 Dec Hum Reprod The regulation and signalling of anti-Müllerian hormone in human granulosa cells: relevance to polycystic ovary syndrome.
2019 Dec Cell Chem Biol A Selective Ligand for Estrogen Receptor Proteins Discriminates Rapid and Genomic Signaling.
2019 Nov iScience Androgen Receptor Is a Non-canonical Inhibitor of Wild-Type and Mutant Estrogen Receptors in Hormone Receptor-Positive Breast Cancers.
2019 J Ginseng Res Ginsenoside Rg1 activates ligand-independent estrogenic effects via rapid estrogen receptor signaling pathway.
2019 Nov Cell Commun Signal GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients.
2020 Feb Toxicol Lett Metalloestrogenic effects of cadmium are absent in long-term estrogen-deprived MCF-7 cells: Evidence for the involvement of constitutively activated estrogen receptor α and very low expression of G protein-coupled estrogen receptor 1.
2019 Nov Can J Physiol Pharmacol Depolarization of pacemaker potentials by caffeic acid phenethyl ester in interstitial cells of Cajal from the murine small intestine.
2020 Bone The effect of oestrogen on mandibular condylar cartilage via hypoxia-inducible factor-2α during osteoarthritis development.
2019 Bratisl Lek Listy Atorvastatin enhances anti-apoptotic effects of tamoxifen on melanoma cancer cells.
2019 Oct Genes Brain Behav The effects of tamoxifen on mouse behavior.
2019 Oct Biomol Ther (Seoul) Involvement of Estrogen Receptor-α in the Activation of Nrf2-Antioxidative Signaling Pathways by Silibinin in Pancreatic β-Cells.
2012 LiverTox: Clinical and Re... Selective Estrogen Receptor Modulators
2019 Oct Br J Pharmacol Activation of oestrogen receptor α induces a novel form of LTP at hippocampal temporoammonic-CA1 synapses.
2019 Oct Int J Mol Sci A Novel Mechanism of S-equol Action in Neurons and Astrocytes: The Possible Involvement of GPR30GPER1.
2019 Front Oncol Treatment of Breast Cancer With Gonadotropin-Releasing Hormone Analogs.
2020 Jan Cancer Lett Three-dimensional oxabicycloheptene sulfonate targets the homologous recombination and repair programmes through estrogen receptor α antagonism.
2019 Oct Nutrients Equol Pretreatment Protection of SH-SY5Y Cells against Aβ (25-35)-Induced Cytotoxicity and Cell-Cycle Reentry via Sustaining Estrogen Receptor Alpha Expression.
2019 Diabetes Metab Syndr Obes Estrogen receptor inhibition enhances cold-induced adipocyte beiging and glucose tolerance.
2020 J Thorac Oncol Inhibiting Pathways Predicted From a Steroid Hormone Gene Signature Yields Synergistic Antitumor Effects in NSCLC.
2019 Nov Horm Behav Reducing luteinizing hormone levels after ovariectomy improves spatial memory: Possible role of brain-derived neurotrophic factor.
2019 PLoS Biol The developmental Wnt signaling pathway effector β-cateninTCF mediates hepatic functions of the sex hormone estradiol in regulating lipid metabolism.
2019 Exp Eye Res The neuroprotective effects of novel estrogen receptor GPER1 in mouse retinal ganglion cell degeneration.
2019 Oct Sci Rep Unraveling FATP1, regulated by ER-β, as a targeted breast cancer innovative therapy.
2019 eNeuro Neuroestrogen-Dependent Transcriptional Activity in the Brains of ERE-Luciferase Reporter Mice following Short- and Long-Term Ovariectomy.
2020 Breast Cancer Res Treat Pharmacokinetic and pharmacodynamic analysis of fulvestrant in preclinical models of breast cancer to assess the importance of its estrogen receptor-α degrader activity in antitumor efficacy.
2019 Reprod Biomed Online Oxytocin antagonism reverses the effects of high oestrogen levels and oxytocin on decidualization and cyclooxygenase activity in endometrial tissues.
2019 Sep Pharmaceuticals (Basel) Tamoxifen Protects from Vesicular Stomatitis Virus Infection.
2019 J Mol Endocrinol Low-dose Bisphenol-A regulates inflammatory cytokines through GPR30 in mammary adipose cells.
2019 Nov Eur J Pharmacol ER-mediated anti-tumor effects of shikonin on breast cancer.
2019 Oct ACS Chem Neurosci Activation of G-Protein-Coupled Receptor 30 Protects Neurons against Excitotoxicity through Inhibiting Excessive Autophagy Induced by Glutamate.
2020 Jan Mol Cell Endocrinol The effects of acute BPA exposure on skeletal muscle mitochondrial function and glucose metabolism.
2019 Dec Am J Physiol Cell Physiol cGMP-dependent protein kinase II determines β-catenin accumulation that is essential for uterine decidualization in mice.
2019 Steroids Rapid signalling responses via the G protein-coupled estrogen receptor, GPER, in a hippocampal cell line.
2019 Am J Transl Res Cnidium lactone stimulates osteogenic differentiation of bone marrow mesenchymal stem cells via BMP-2smad-signaling cascades mediated by estrogen receptor.
2019 Geroscience Tamoxifen induction of Cre recombinase does not cause long-lasting or sexually divergent responses in the CNS epigenome or transcriptome: implications for the design of aging studies.
2019 Alcohol Clin Exp Res Effects of Alcohol and Estrogen Receptor Blockade Using ICI 182,780 on Bone in Ovariectomized Rats.
2019 Comp Biochem Physiol B Bi... Regulation of triglyceride synthesis by estradiol in the livers of hybrid tilapia (Oreochromis niloticus ♀ × O. aureus ♂).
2019 Arch Toxicol A nongenomic mechanism for "metalloestrogenic" effects of cadmium in human uterine leiomyoma cells through G protein-coupled estrogen receptor.
2019 Dec Adv Physiol Educ Altering rat sexual behavior to teach hormonal regulation of brain imprinting.
2019 PLoS One 17-β estradiol exerts anti-inflammatory effects through activation of Nrf2 in mouse embryonic fibroblasts.
2019 Front Oncol Novel Diphenylamine Analogs Induce Mesenchymal to Epithelial Transition in Triple Negative Breast Cancer.
2019 Aug Int J Environ Res Public ... The Effects of Endocrine Disrupting Chemicals on Biomarkers of Inflammation Produced by Lipopolysaccharide Stimulated RAW264.7 Macrophages.
2019 Oct Toxicol Appl Pharmacol Differential activity of BPA, BPAF and BPC on zebrafish estrogen receptors in vitro and in vivo.
2019 Dec J Clin Endocrinol Metab Treatment of Menopausal Vasomotor Symptoms With Fezolinetant, a Neurokinin 3 Receptor Antagonist: A Phase 2a Trial.