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Recent literature: Estrogen receptor antagonist
Date Journal Article title
2019 Jun Toxicol Appl Pharmacol Predicting estrogen receptor binding of chemicals using a suite of in silico methods - Complementary approaches of (Q)SAR, molecular docking and molecular dynamics.
2019 Jun Aging (Albany NY) Long-time qingyan formula extract treatment exerts estrogenic activities on reproductive tissues without side effects in ovariectomized rats and via active ER to ERE-independent gene regulation.
2019 Onco Targets Ther A temperature-sensitive phase-change hydrogel of tamoxifen achieves the long-acting antitumor activation on breast cancer cells.
2019 Jun Food Funct Hepatoprotection of auraptene from the peels of citrus fruits against 17α-ethinylestradiol-induced cholestasis in mice by activating farnesoid X receptor.
2019 Jun Cells The Peptide ERα17p Is a GPER Inverse Agonist that Exerts Antiproliferative Effects in Breast Cancer Cells.
2019 Oxid Med Cell Longev The Protective Roles of Estrogen Receptor iβi in Renal Calcium Oxalate Crystal Formation iviai Reducing the Liver Oxalate Biosynthesis and Renal Oxidative Stress-Mediated Cell Injury.
2019 Jun J Steroid Biochem Mol Biol G protein-coupled estrogen receptor is involved in the neuroprotective effect of IGF-1 against MPTPMPP+-induced dopaminergic neuronal injury.
2019 Jun Proc Natl Acad Sci U S A Hypoxia-induced switch in SNAT2SLC38A2 regulation generates endocrine resistance in breast cancer.
2018 Int Cancer Conf J Tamoxifen withdrawal in women with progressive metastatic breast cancer: a case series of six patients.
2019 May Am J Physiol Regul Integr... Expression and Function of Nesfatin-1 are Altered by Stage of the Estrous Cycle.
2019 Theranostics Highly bright and stable NIR-BRET with blue-shifted coelenterazine derivatives for deep-tissue imaging of molecular events iin vivoi.
2019 Acta Histochem Do estrogens regulate lipid status in testicular steroidogenic Leydig cell?
2019 May Psychoneuroendocrinology Dissociable involvement of estrogen receptors in perirhinal cortex-mediated object-place memory in male rats.
2019 May J Clin Endocrinol Metab Aldosterone Stimulates Its Biosynthesis Via A Novel GPER Mediated Mechanism.
2019 Cell Signal Estrogen receptor alpha regulates the Wntβ-catenin signaling pathway in colon cancer by targeting the NOD-like receptors.
2019 May Arch Toxicol The in vivo developmental toxicity of diethylstilbestrol (DES) in rat evaluated by an alternative testing strategy.
2019 Jun Hum Reprod Peroxisome proliferator-activated receptor-γ coactivator 1α-mediated pathway as a possible therapeutic target in endometriosis.
2019 Int J Nanomedicine Gold nanoparticle uptake is enhanced by estradiol in MCF-7 breast cancer cells.
2019 Bioorg Chem Identification of 10-dehydrooxyglycyuralin E as a selective human estrogen receptor alpha partial agonist.
2019 May Cancer Res Treat Low Doses of Nonylphenol Promote Growth of Colon Cancer Cells through Activation of ERK12 via G Protein‒Coupled Receptor 30.
2019 May Sci Rep Determination and analysis of agonist and antagonist potential of naturally occurring flavonoids for estrogen receptor (ERα) by various parameters and molecular modelling approach.
2019 May Clin Exp Immunol Mitigating placental injuries through up-regulating DAF in experimental APS mice: new mechanism of progesterone.
2019 An Bras Dermatol Fulvestrant-induced toxic epidermal necrolysis.
2019 Apr Toxicol Sci Quizalofop-p-Ethyl Induces Adipogenesis in 3T3-L1 Adipocytes.
2019 May Pharmacol Ther Consideration of breast cancer type in targeting the androgen receptor.
2019 May Mol Cell Biochem Estrogen-independent role of ERα in ovarian cancer progression induced by leptinOb-Rb axis.
2019 May Chem Biol Drug Des ER alpha selective chromone, isoxazolylchromones, induces ROS-mediated cell death without autophagy.
2019 May Gen Comp Endocrinol Role for androgens in determination of ovarian fate in the common snapping turtle, Chelydra serpentina.
2019 Aug J Pharm Biomed Anal Pharmacokinetics and metabolism of H3B-6545, a selective estrogen receptor covalent antagonist, in dog plasma by liquid chromatography combined with electrospray ionization tandem mass spectrometry.
2019 Feb Phytomedicine Effect and mechanism of psoralidin on promoting osteogenesis and inhibiting adipogenesis.
2019 May J Radiat Res Mechanism and therapeutic window of a genistein nanosuspension to protect against hematopoietic-acute radiation syndrome.
2019 Feb Phytomedicine Chinese yam extract and adenosine attenuated LPS-induced cardiac dysfunction by inhibiting RAS and apoptosis via the ER-mediated activation of SHCRasRaf1 pathway.
2019 Jun Chem Biol Interact Activation of G protein-coupled receptor 30 by flavonoids leads to expression of acetylcholinesterase in cultured PC12 cells.
2019 Apr FASEB J Mammary adipose stromal cells derived from obese women reduce sensitivity to the aromatase inhibitor anastrazole in an organotypic breast model.
2019 Breast Cancer Res Treat Propagation of functional estrogen receptor positive normal human breast cells in 3D cultures.
2019 Jun J Neurosci Estrogen-Dependent Functional Spine Dynamics in Neocortical Pyramidal Neurons of the Mouse.
2019 Apr Cancers (Basel) Combined Targeting of Estrogen Receptor Alpha and XPO1 Prevent Akt Activation, Remodel Metabolic Pathways and Induce Autophagy to Overcome Tamoxifen Resistance.
2019 Horm Behav Plasma membrane G protein-coupled estrogen receptor 1 (GPER) mediates rapid estradiol facilitation of sexual receptivity through the orphanin-FQ-ORL-1 system in estradiol primed female rats.
2019 Jun Mol Cell Endocrinol Estrogen interacts with glucocorticoids in the regulation of lipocalin 2 expression in human adipose tissue. Reciprocal roles of estrogen receptor α and β in insulin resistance?
2019 Apr Cancer Res Estrogen Receptor Covalent Antagonists: The Best Is Yet to Come.
2019 Mar Oncol Res E2-induced activation of the NLRP3 inflammasome triggers pyroptosis and inhibits autophagy in HCC cells.
2019 May Toxicology Estimation of competitive antagonist affinity by the Schild method and from functional inhibition curves using a novel form of the Gaddum equation.
2019 Mar J Neuroendocrinol Age-dependent regulation by androgens of gene expression in the anterior hypothalamus and stress-induced release of adrenal hormones in adolescent and adult male rats.
2019 Domest Anim Endocrinol Peripheral administration of κ-opioid receptor antagonist stimulates gonadotropin-releasing hormone pulse generator activity in ovariectomized, estrogen-treated female goats.
2019 Jul Ecotoxicol Environ Saf A comparison of endocrine disruption potential of nonylphenol ethoxylate, vanillin ethoxylate, 4-n-nonylphenol and vanillin in vitro.
2019 Climacteric Beyond estrogen: advances in tissue selective estrogen complexes and selective estrogen receptor modulators.
2019 J Neuroendocrinol Oestradiol acts through its beta receptor to increase vasopressin neuronal activation and secretion induced by dehydration.
2019 Apr Biochem Biophys Res Commun Estradiol stimulates cell proliferation via classic estrogen receptor-alpha and G protein-coupled estrogen receptor-1 in human renal tubular epithelial cell primary cultures.
2019 Biochim Biophys Acta Mol ... Lactate dehydrogenase A regulates autophagy and tamoxifen resistance in breast cancer.
2019 Mol Med Rep Estrogen receptor β presses inflammation and the progression of prostate cancer.
2019 Apr Mol Cell Endocrinol Maternal exposure to imazalil disrupts the endocrine system in F1 generation mice.
2019 Diabetes Fasting-Induced Transcription Factors Repress Vitamin D Bioactivation, a Mechanism for Vitamin D Deficiency in Diabetes.
2019 Environ Pollut Computational insights on agonist and antagonist mechanisms of estrogen receptor α induced by bisphenol A analogues.
2019 Jun Toxicol Sci Tetrabromobisphenol A (TBBPA) Alters ABC Transport at the Blood-Brain Barrier.
2019 Biol Pharm Bull Novel Ridaifen-B Structure Analog Induces Apoptosis and Autophagy Depending on Pyrrolidine Side Chain.
2019 Neural Regen Res GPER agonist G1 presses neuronal apoptosis mediated by endoplasmic reticulum stress after cerebral ischemiareperfusion injury.
2019 Jun Behav Brain Res Alteration in oxytocin levels induced by early social environment affects maternal behavior and estrogen receptor alpha in mandarin voles (Microtus mandarinus).
2019 Steroids Design and synthesis of fluorescently labeled steroidal antiestrogens.
2019 Jul Brain Res G protein-coupled estrogen receptor 1 negatively regulates the proliferation of mouse-derived neural stemprogenitor cells via extracellular signal-regulated kinase pathway.
2019 Apr Biochem Biophys Res Commun Estrogen receptors participate in carcinogenesis signaling pathways by directly regulating NOD-like receptors.
2019 Jun Toxicol Sci Molecular Mechanisms of Polybrominated Diphenyl Ethers (BDE-47, BDE-100, and BDE-153) in Human Breast Cancer Cells and Patient-Derived Xenografts.
2019 Feb J Exp Clin Cancer Res Aberrant fatty acid profile and FFAR4 signaling confer endocrine resistance in breast cancer.
2019 Front Pharmacol Repeated Administration of Norbinaltorphimine Produces Cumulative Kappa Opioid Receptor Inactivation.
2019 Exp Ther Med Oestrogen inhibits PTPRO to prevent the apoptosis of renal podocytes.
2019 Feb Immunol Cell Biol Macrophage ERα promoted invasion of endometrial cancer cell by mTORKIF5B-mediated epithelial to mesenchymal transition.
2019 Front Pharmacol iCalculus Bovis Sativusi Improves Bile Acid Homeostasis via Farnesoid X Receptor-Mediated Signaling in Rats With Estrogen-Induced Cholestasis.
2019 eNeuro Estradiol-Induced Potentiation of Dopamine Release in Dorsal Striatum Following Amphetamine Administration Requires Estradiol Receptors and mGlu5.
2018 Apr Reproduction Notch activity mediates oestrogen-induced stromal cell invasion in endometriosis.
2019 Toxicol In Vitro Assessment of human estrogen receptor agonisticantagonistic effects of veterinary drugs used for livestock and farmed fish by OECD in vitro stably transfected transcriptional activation assays.
2019 Feb Curr Treat Options Oncol Management of Nonmetastatic Castration-Resistant Prostate Cancer: Recent Advances and Future Direction.
2019 May Ecotoxicol Environ Saf Estrogen receptor β plays a protective role in zearalenone-induced oxidative stress in normal prostate epithelial cells.
2019 Evid Based Complement Alt... Adenosine Attenuates LPS-Induced Cardiac Dysfunction by Inhibition of Mitochondrial Function via the ER Pathway.
2019 Apr Mol Cell Endocrinol Rapid effect of bisphenol A on glutamate-induced Ca2+ influx in hippocampal neurons of rats.
2019 Jan Transl Psychiatry Estradiol modulation of the renin-angiotensin system and the regulation of fear extinction.
2019 May Clin Cancer Res Cell-Proliferation Imaging for Monitoring Response to CDK46 Inhibition Combined with Endocrine-Therapy in Breast Cancer: Comparison of [18F]FLT and [18F]ISO-1 PETCT.