Purchases through the above links give commission which helps fund this website
Recent literature: H1 receptor antagonist
Date Journal Article title
2020 Mar J Pharm Sci Characterization of photodegradation products of bepotastine besilate and in silico evaluation of their ADMET properties.
2020 Feb Clin Neurol Neurosurg Randomized control trial of evaluation of Clemastine effects on visual evoked potential, nerve fiber layer and ganglion cell layer complex in patients with optic neuritis.
2020 Mar J Allergy Clin Immunol Pract The Utility of Measuring Urinary Metabolites of Mast Cell Mediators in Systemic Mastocytosis and Mast Cell Activation Syndrome.
2020 Mar Sci Rep Alterations in histamine responses between juvenile and adult urinary bladder urothelium, lamina propria and detrusor tissues.
2020 Mar Anat Histol Embryol Histamine receptors mediate contraction of reticular groove smooth muscle of adult goats.
2020 Feb Eur J Pharmacol Potential synergistic effects of novel hematopoietic prostaglandin D synthase inhibitor TAS-205 and different types of anti-allergic medicine on nasal obstruction in a Guinea pig model of experimental allergic rhinitis.
2020 Feb J Appl Toxicol Wastewater-derived antagonistic activities of G protein-coupled receptor-acting pharmaceuticals in river water.
2020 Feb Epilepsy Behav Betahistine, prevents kindling, ameliorates the behavioral comorbidities and neurodegeneration induced by pentylenetetrazole.
2020 Psychoneuroendocrinology Olanzapine increases AMPK-NPY orexigenic signaling by disrupting H1R-GHSR1a interaction in the hypothalamic neurons of mice.
2020 Jan Sci Rep Corticosteroid reduction by addition of cetirizine and montelukast in biopsy-proven minimal-change nephrotic syndrome concomitant with allergic disorders.
2020 Jan J Cancer Educ Evaluation of Adherence to Antiemetic Treatment Guidelines in Patients With Chemotherapy-Induced Nausea and Vomiting in Teaching Hospitals in Tehran.
2020 Feb Environ Sci Technol Biological Activity-Based Prioritization of Pharmaceuticals in Wastewater for Environmental Monitoring: G Protein-Coupled Receptor Inhibitors.
2020 Jan Trials Efficacy of switching to bilastine, a histamine H1 receptor antagonist, in patients with chronic spontaneous urticaria (H1-SWITCH): study protocol for a randomized controlled trial.
2020 Cell Calcium Unexpected Ca2+-mobilization of oxaliplatin via H1 histamine receptors.
2019 Front Oncol Mast Cells May Differentially Regulate Growth of Lymphoid Neoplasms by Opposite Modulation of Histamine Receptors.
2020 Feb Am J Physiol Renal Physiol Histamine induces peripheral and central hypersensitivity to bladder distension via the histamine H1 receptor and TRPV1.
2019 Curr Drug Metab Developing a High-performance Liquid Chromatography Method for Simultaneous Determination of Loratadine and its Metabolite Desloratadine in Human Plasma.
2019 Nihon Yakurigaku Zasshi [Preclinical pharmacological profiles and clinical efficacy of the novel antipsychotic drug brexpiprazole (REXULTI® Tablets 1 mg, 2 mg)].
2019 J Pediatr Pharmacol Ther Cetirizine as a Causative Agent for Drug Induced Methemoglobinemia: A Case Report and Review.
2020 Feb J Chem Inf Model Structural Insights into the Ligand Binding Domain of the Glucocorticoid Receptor: A Molecular Dynamics Study.
2019 Oct Pharmacology Pharmacological Characteristics of Anxiolytics on Acetylcholine-Induced Contractions in Rat Detrusor Smooth Muscle.
2019 Clin Transl Allergy Histamine H4 receptor regulates IL-6 and INF-γ secretion in native monocytes from healthy jects and patients with allergic rhinitis.
2019 Drug Des Devel Ther Effects of loratadine, a histamine H1 receptor antagonist, on the skeletal system of young male rats.
2020 Subst Use Misuse Quetiapine Abuse Fourteen Years Later: Where Are We Now? A Systematic Review.
2019 Pharmacol Biochem Behav Acute and chronic interactive treatments of serotonin 5HT2C and dopamine D1 receptor systems for decreasing nicotine self-administration in female rats.
2019 Oct Bioorg Med Chem Lett Rasagiline derivatives combined with histamine H3 receptor properties.
2019 Antiviral Res FDA-drug screening identifies deptropine inhibiting hepatitis E virus involving the NF-κB-RIPK1-caspase axis.
2019 Biochem Pharmacol KSK19 - Novel histamine H3 receptor ligand reduces body weight in diet induced obese mice.
2019 CNS Neurol Disord Drug Ta... Central Histamine, the H3-Receptor and Obesity Therapy.
2019 Br J Clin Pharmacol Management of peripheral vertigo with antihistamines: New options on the horizon.
2019 Mediators Inflamm Neutrophils Are Dysregulated in Patients with Hereditary Angioedema Types I and II in a Symptom-Free Period.
2019 Aug Eur J Pharmacol Microinjection of histamine and its H3 receptor agonist and antagonist into the agranular insular cortex influence sensory and affective components of neuropathic pain in rats.
2019 Aug Neuroscience Glutamate Activates the Histaminergic Tuberomammillary Nucleus and Increases Wakefulness in Rats.
2019 Jun BMC Cancer The safety and tolerability of combined immune checkpoint inhibitors (anti-PD-1PD-L1 plus anti-CTLA-4): a systematic review and meta-analysis.
2019 May Int J Mol Sci Effect of Bilastine on Diabetic Nephropathy in DBA2J Mice.
2019 Mol Immunol Phenothiazine antipsychotics exhibit dual properties in pseudo-allergic reactions: Activating MRGPRX2 and inhibiting the H1 receptor.
2019 J Clin Pharm Ther The combination of loratadine with famotidine to relieve the symptoms of urinary frequency in female patients with bladder function disorders:First report of three cases.
2019 Jul Neuroscience Allergen-induced histaminergic and non-histaminergic activation of itch C-fiber nerve terminals in mouse skin.
2019 Front Neurosci The Systemic Administration of the Histamine H1 Receptor AntagonistInverse Agonist Chlorpheniramine to Pregnant Rats Impairs the Development of Nigro-Striatal Dopaminergic Neurons.
2019 Apr Int J Mol Sci A Metadynamics-Based Protocol for the Determination of GPCR-Ligand Binding Modes.
2019 Am J Rhinol Allergy Leukotriene Receptor Antagonist Addition to H1-Antihistamine Is Effective for Treating Allergic Rhinitis: A Systematic Review and Meta-analysis.
2019 Clin Exp Allergy Idiopathic anaphylaxis.
2019 Apr Int J Mol Sci The Role of Histamine in the Pathophysiology of Asthma and the Clinical Efficacy of Antihistamines in Asthma Therapy.
2019 Neuropharmacology Persistent activation of histamine H1 receptors in the hippocampal CA1 region enhances NMDA receptor-mediated synaptic excitation and long-term potentiation in astrocyte- and D-serine-dependent manner.
2019 Artif Cells Nanomed Biote... The effects of histamine H1 type receptor (H1R) in regulating osteoblastic cell differentiation and mineralization.
2019 Apr Toxins (Basel) iD. russeliii Venom Mediates Vasodilatation of Resistance Like Arteries via Activation of Kv and KCa Channels.
2019 Mar J Headache Pain Histamine and migraine revisited: mechanisms and possible drug targets.
2019 Aug Rhinology Azelastine nasal spray inhibiting sympathetic function on human nasal mucosa in patients with allergy rhinitis.
2019 Biomed Res Int Extracellular Signal-Regulated Kinase Mediates Ebastine-Induced Human Follicle Dermal Papilla Cell Proliferation.
2019 Int Arch Allergy Immunol Effects of an Oral CRTh2 Antagonist (AZD1981) on Eosinophil Activity and Symptoms in Chronic Spontaneous Urticaria.
2019 Mar Sci Rep Histamine modulation of urinary bladder urothelium, lamina propria and detrusor contractile activity via H1 and H2 receptors.
2019 Adv Clin Exp Med Long-term administration of fenspiride has no negative impact on bone mineral density and bone turnover in young growing rats.
2019 J Alzheimers Dis Treatment of Alzheimer's Disease: Trazodone, Sleep, Serotonin, Norepinephrine, and Future Directions.
2019 J Pharm Pharm Sci Effect of the Fexofenadine on the expression of HRH-1 and HRH-4 receptor in Peripheral Blood Mononuclear Cell isolated from children with diagnosed allergy - in vitro study Short communication.
2019 Cardiovasc Toxicol Characterization of microminipig as a laboratory animal for safety pharmacology study by analyzing fluvoxamine-induced cardiovascular and dermatological adverse reactions.
2019 Biol Pharm Bull Assessment of Inhibitory Effects of Hypnotics on Acetylcholine-Induced Contractions in Isolated Rat Urinary Bladder Smooth Muscle.
2019 Mar Eur J Pharmacol β2-Microglobulin, interleukin-31, and arachidonic acid metabolites (leukotriene B4 and thromboxane A2) are involved in chronic renal failure-associated itch-associated responses in mice.
2019 Feb J Chem Inf Model Communication between the Ligand-Binding Pocket and the Activation Function-2 Domain of Androgen Receptor Revealed by Molecular Dynamics Simulations.
2018 Polim Med Formulation and characterization of oral rapid disintegrating tablets of levocetirizine.
2019 Drug Metab Dispos Clopidogrel and Gemfibrozil Strongly Inhibit the CYP2C8-Dependent Formation of 3-Hydroxydesloratadine and Increase Desloratadine Exposure In Humans.
2018 Dec Cells Extracellular Histones Activate Plasma Membrane Toll-Like Receptor 9 to Trigger Calcium Oscillations in Rat Pancreatic Acinar Tumor Cell AR4-2J.
2018 Acta Otorhinolaryngol Ital Report from a Consensus Conference on the treatment of Ménière's disease with betahistine: rationale, methodology and results.
2018 Front Cell Neurosci Clemastine Alleviates Depressive-Like Behavior Through Reversing the Imbalance of Microglia-Related Pro-inflammatory State in Mouse Hippocampus.
2019 Jan Am J Physiol Gastrointest... Distinct roles of histamine H1- and H2-receptor signaling pathways in inflammation-associated colonic tumorigenesis.
2018 Acute Med Surg Cardiac arrest caused by diphenhydramine overdose.
2019 Haematologica Hypersensitivity reactions to asparaginase in mice are mediated by anti-asparaginase IgE and IgG and the immunoglobulin receptors FcεRI and FcγRIII.
2018 Nov Neurosci Lett Intracerebellar microinjection of histaminergic compounds on locomotor and exploratory behaviors in mice.
2018 Oct Environ Sci Technol Quantification of Pharmaceutical Related Biological Activity in Effluents from Wastewater Treatment Plants in UK and Japan.
2018 Oct Blood B-cell receptor-mediated NFATc1 activation induces IL-10STAT3PD-L1 signaling in diffuse large B-cell lymphoma.
2018 Nov Eur J Pharmacol The long duration of action of the second generation antihistamine bilastine coincides with its long residence time at the histamine H1 receptor.
2019 Handb Exp Pharmacol Other Antidepressants.
2018 Oct Eur J Pharmacol Histamine H4 receptor mediates chemotaxis of human lung mast cells.
2018 Cancer Immunol Res A2AR Antagonism with CPI-444 Induces Antitumor Responses and Augments Efficacy to Anti-PD-(L)1 and Anti-CTLA-4 in Preclinical Models.
2018 Nov Brain Res Intracerebroventricular injection of histamine induces the hypothalamic-pituitary-gonadal axis activation in male rats.
2018 Biomed Pharmacother Histamine H1 type receptor antagonist loratadine ameliorates oxidized LDL induced endothelial dysfunction.