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Recent literature: H1 receptor antagonist
Date Journal Article title
2019 Nov J Chem Inf Model Structural insights into the ligand binding domain of the glucocorticoid receptor: a molecular dynamics study.
2019 Oct Pharmacology Pharmacological Characteristics of Anxiolytics on Acetylcholine-Induced Contractions in Rat Detrusor Smooth Muscle.
2019 Clin Transl Allergy Histamine H4 receptor regulates IL-6 and INF-γ secretion in native monocytes from healthy jects and patients with allergic rhinitis.
2019 Drug Des Devel Ther Effects of loratadine, a histamine H1 receptor antagonist, on the skeletal system of young male rats.
2019 Oct Subst Use Misuse Quetiapine Abuse Fourteen Years Later: Where Are We Now? A Systematic Review.
2019 Pharmacol Biochem Behav Acute and chronic interactive treatments of serotonin 5HT2C and dopamine D1 receptor systems for decreasing nicotine self-administration in female rats.
2019 Oct Bioorg Med Chem Lett Rasagiline derivatives combined with histamine H3 receptor properties.
2019 Antiviral Res FDA-drug screening identifies deptropine inhibiting hepatitis E virus involving the NF-κB-RIPK1-caspase axis.
2019 Biochem Pharmacol KSK19 - Novel histamine H3 receptor ligand reduces body weight in diet induced obese mice.
2019 Jul CNS Neurol Disord Drug Ta... Central Histamine, The H3-Receptor and Obesity Therapy.
2019 Br J Clin Pharmacol Management of peripheral vertigo with antihistamines: New options on the horizon.
2019 Aug Eur J Pharmacol Microinjection of histamine and its H3 receptor agonist and antagonist into the agranular insular cortex influence sensory and affective components of neuropathic pain in rats.
2019 Aug Neuroscience Glutamate Activates the Histaminergic Tuberomammillary Nucleus and Increases Wakefulness in Rats.
2019 May Int J Mol Sci Effect of Bilastine on Diabetic Nephropathy in DBA2J Mice.
2019 Mol Immunol Phenothiazine antipsychotics exhibit dual properties in pseudo-allergic reactions: Activating MRGPRX2 and inhibiting the H1 receptor.
2019 Jul Neuroscience Allergen-induced histaminergic and non-histaminergic activation of itch C-fiber nerve terminals in mouse skin.
2019 Front Neurosci The Systemic Administration of the Histamine H1 Receptor AntagonistInverse Agonist Chlorpheniramine to Pregnant Rats Impairs the Development of Nigro-Striatal Dopaminergic Neurons.
2019 Apr Int J Mol Sci A Metadynamics-Based Protocol for the Determination of GPCR-Ligand Binding Modes.
2019 Am J Rhinol Allergy Leukotriene Receptor Antagonist Addition to H1-Antihistamine Is Effective for Treating Allergic Rhinitis: A Systematic Review and Meta-analysis.
2019 Clin Exp Allergy Idiopathic anaphylaxis.
2019 Apr Int J Mol Sci The Role of Histamine in the Pathophysiology of Asthma and the Clinical Efficacy of Antihistamines in Asthma Therapy.
2019 Neuropharmacology Persistent activation of histamine H1 receptors in the hippocampal CA1 region enhances NMDA receptor-mediated synaptic excitation and long-term potentiation in astrocyte- and D-serine-dependent manner.
2019 Artif Cells Nanomed Biote... The effects of histamine H1 type receptor (H1R) in regulating osteoblastic cell differentiation and mineralization.
2019 Apr Toxins (Basel) iD. russeliii Venom Mediates Vasodilatation of Resistance Like Arteries via Activation of Kv and KCa Channels.
2019 Mar J Headache Pain Histamine and migraine revisited: mechanisms and possible drug targets.
2019 Aug Rhinology Azelastine nasal spray inhibiting sympathetic function on human nasal mucosa in patients with allergy rhinitis.
2019 Biomed Res Int Extracellular Signal-Regulated Kinase Mediates Ebastine-Induced Human Follicle Dermal Papilla Cell Proliferation.
2019 Int Arch Allergy Immunol Effects of an Oral CRTh2 Antagonist (AZD1981) on Eosinophil Activity and Symptoms in Chronic Spontaneous Urticaria.
2019 Mar Sci Rep Histamine modulation of urinary bladder urothelium, lamina propria and detrusor contractile activity via H1 and H2 receptors.
2019 Adv Clin Exp Med Long-term administration of fenspiride has no negative impact on bone mineral density and bone turnover in young growing rats.
2019 J Alzheimers Dis Treatment of Alzheimer's Disease: Trazodone, Sleep, Serotonin, Norepinephrine, and Future Directions.
2019 J Pharm Pharm Sci Effect of the Fexofenadine on the expression of HRH-1 and HRH-4 receptor in Peripheral Blood Mononuclear Cell isolated from children with diagnosed allergy - in vitro study Short communication.
2019 Cardiovasc Toxicol Characterization of microminipig as a laboratory animal for safety pharmacology study by analyzing fluvoxamine-induced cardiovascular and dermatological adverse reactions.
2019 Biol Pharm Bull Assessment of Inhibitory Effects of Hypnotics on Acetylcholine-Induced Contractions in Isolated Rat Urinary Bladder Smooth Muscle.
2019 Mar Eur J Pharmacol β2-Microglobulin, interleukin-31, and arachidonic acid metabolites (leukotriene B4 and thromboxane A2) are involved in chronic renal failure-associated itch-associated responses in mice.
2019 Feb J Chem Inf Model Communication between the Ligand-Binding Pocket and the Activation Function-2 Domain of Androgen Receptor Revealed by Molecular Dynamics Simulations.
2018 Polim Med Formulation and characterization of oral rapid disintegrating tablets of levocetirizine.
2019 Drug Metab Dispos Clopidogrel and Gemfibrozil Strongly Inhibit the CYP2C8-Dependent Formation of 3-Hydroxydesloratadine and Increase Desloratadine Exposure In Humans.
2018 Dec Cells Extracellular Histones Activate Plasma Membrane Toll-Like Receptor 9 to Trigger Calcium Oscillations in Rat Pancreatic Acinar Tumor Cell AR4-2J.
2018 Acta Otorhinolaryngol Ital Report from a Consensus Conference on the treatment of Ménière's disease with betahistine: rationale, methodology and results.
2018 Front Cell Neurosci Clemastine Alleviates Depressive-Like Behavior Through Reversing the Imbalance of Microglia-Related Pro-inflammatory State in Mouse Hippocampus.
2019 Jan Am J Physiol Gastrointest... Distinct roles of histamine H1- and H2-receptor signaling pathways in inflammation-associated colonic tumorigenesis.
2018 Acute Med Surg Cardiac arrest caused by diphenhydramine overdose.
2019 Haematologica Hypersensitivity reactions to asparaginase in mice are mediated by anti-asparaginase IgE and IgG and the immunoglobulin receptors FcεRI and FcγRIII.
2018 Nov Neurosci Lett Intracerebellar microinjection of histaminergic compounds on locomotor and exploratory behaviors in mice.
2018 Oct Environ Sci Technol Quantification of Pharmaceutical Related Biological Activity in Effluents from Wastewater Treatment Plants in UK and Japan.
2018 Oct Blood B-cell receptor-mediated NFATc1 activation induces IL-10STAT3PD-L1 signaling in diffuse large B-cell lymphoma.
2018 Nov Eur J Pharmacol The long duration of action of the second generation antihistamine bilastine coincides with its long residence time at the histamine H1 receptor.
2019 Handb Exp Pharmacol Other Antidepressants.
2018 Oct Eur J Pharmacol Histamine H4 receptor mediates chemotaxis of human lung mast cells.
2018 Cancer Immunol Res A2AR Antagonism with CPI-444 Induces Antitumor Responses and Augments Efficacy to Anti-PD-(L)1 and Anti-CTLA-4 in Preclinical Models.
2018 Nov Brain Res Intracerebroventricular injection of histamine induces the hypothalamic-pituitary-gonadal axis activation in male rats.
2018 Biomed Pharmacother Histamine H1 type receptor antagonist loratadine ameliorates oxidized LDL induced endothelial dysfunction.
2019 J Biomol Struct Dyn Structure investigation, enrichment analysis and structure-based repurposing of FDA-approved drugs as inhibitors of BET-BRD4.
2018 Zh Nevrol Psikhiatr Im S ... [The role of central histamine receptor blockers in the treatment of insomnia].
2018 Sep Eur J Pharmacol Evaluation of different classes of histamine H1 and H2 receptor antagonist effects on neuropathic nociceptive behavior following tibial nerve transection in rats.
2018 Jun Pediatr Emerg Care Effects of Glucocorticoids on Hospitalized Children With Anaphylaxis.
2018 Acta Biol Hung Effects of the venom of the brown bullhead catfish (Ameiurus nebulosus) on isolated smooth muscles.
2018 Hum Immunol IL-1β induces expression of costimulatory molecules and cytokines but not immune feedback regulators in dendritic cells.
2018 Neuropharmacology Enhanced central histaminergic transmission attenuates compulsive-like behavior in mice.
2018 Aug ChemMedChem Development of Novel Inhibitors for Histone Methyltransferase SET79 based on Cyproheptadine.
2018 J Recept Signal Transduct... Silencing of H4R inhibits the production of IL-1β through SAPKJNK signaling in human mast cells.
2018 Sep Am J Physiol Endocrinol M... Melanotan II causes hypothermia in mice by activation of mast cells and stimulation of histamine 1 receptors.
2018 J Asthma Allergy Methacholine challenge testing: comparative pharmacology.
2018 Cell Physiol Biochem Modulation of Mast Cell Toll-Like Receptor 3 Expression and Cytokines Release by Histamine.
2018 Pharmacol Biochem Behav Anticonvulsant evaluation of novel non-imidazole histamine H3R antagonists in different convulsion models in rats.
2018 Apr Basic Clin Pharmacol Toxicol Effects of UGT1A1, CYP3A5 and ABCB1 Genetic Variants on Pharmacokinetics of Antihistamine Drug Mizolastine in Chinese Healthy Volunteers.
2018 Hautarzt [Allergic emergencies].
2018 Drug Deliv Development of Kupffer cell targeting type-I interferon for the treatment of hepatitis via inducing anti-inflammatory and immunomodulatory actions.
2018 May Bioorg Med Chem Novel naphthyloxy derivatives - Potent histamine H3 receptor ligands. Synthesis and pharmacological evaluation.
2018 Neurosci Bull Cyproheptadine Regulates Pyramidal Neuron Excitability in Mouse Medial Prefrontal Cortex.
2018 Front Endocrinol (Lausanne) Histamine Regulates Molecular Clock Oscillations in Human Retinal Pigment Epithelial Cells iviai H1 Receptors.
2018 Yakugaku Zasshi [Detection of Physiological Activity of Pharmaceuticals in Wastewater and River Water].
2018 Pharmacol Rev Drugs for Insomnia beyond Benzodiazepines: Pharmacology, Clinical Applications, and Discovery.
2018 J Invest Dermatol Persistent Extracellular Signal-Regulated Kinase Activation by the Histamine H4 Receptor in Spinal Neurons Underlies Chronic Itch.