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Recent literature: GLP-1 receptor agonist
Date Journal Article title
2019 Feb EJNMMI Res First-in-class positron emission tomography tracer for the glucagon receptor.
2019 Feb Eur J Pharmacol The effect of exenatide (a GLP-1 analog) and sitagliptin (a DPP-4 inhibitor) on plasma platelet-activating factor acetylhydrolase (PAF-AH) activity and concentration in normal and fructose-fed rats.
2019 Feb Obes Rev Semaglutide as a promising antiobesity drug.
2018 Front Psychiatry Bone Status in Obese, Non-diabetic, Antipsychotic-Treated Patients, and Effects of the Glucagon-Like Peptide-1 Receptor Agonist Exenatide on Bone Turnover Markers and Bone Mineral Density.
2019 J Parkinsons Dis Semaglutide is Neuroprotective and Reduces α-Synuclein Levels in the Chronic MPTP Mouse Model of Parkinson's Disease.
2019 Feb Diabetes Obes Metab Evaluating the Long-Term Cost-Effectiveness of ideglira for type 2 diabetes in spain based on Real-World clinical evidence.
2019 Feb J Am Acad Dermatol Reply to: Comment on "Oral diabetes medications other than dipeptidyl peptidase-4 inhibitors are not associated with bullous pemphigoid: A Finnish nationwide case control study" and a case report of glucagon-like peptide-1 receptor agonist induced bullous pemphigoid.
2019 Feb Expert Opin Pharmacother The efficacy and safety of exenatide once weekly in patients with type 2 diabetes.
2019 Feb J Manag Care Spec Pharm Effect of Weight Change on Economic Outcomes Among Persons with Type 2 Diabetes Mellitus in the United States: Beyond Glycemic Control.
2019 Feb Diabetes Obes Metab Generalizability of Glucagon-Like Peptide-1 Receptor Agonist Cardiovascular Outcome Trials to the Overall Type 2 Diabetes Population in the United States.
2019 Jan Prim Care Diabetes Network meta-analysis of nine large cardiovascular outcome trials of new antidiabetic drugs.
2018 Jun Ter Arkh Renal effects of glucagon-like peptide receptor agonists in patients with type 1 diabetes mellitus.
2019 Jan Endocr Connect Incretin-based therapies for patients with type 1 diabetes: a meta-analysis.
2019 Jan Horm Metab Res Exenatide Delays Gastric Emptying in Patients with Type 2 Diabetes Mellitus but not in Those with Gastroparetic Conditions.
2019 Jan Mol Metab GDF15 acts synergistically with liraglutide but is not necessary for the weight loss induced by bariatric surgery in mice.
2019 Jan Diabetologia Effects of combined GIP and GLP-1 infusion on energy intake, appetite and energy expenditure in overweightobese individuals: a randomised, crossover study.
2019 Jan J Neurosci Chronic pression of glucagon-like peptide-1 receptor (GLP1R) mRNA translation in the rat bed nucleus of the stria terminalis reduces anxiety-like behavior and stress-induced hypophagia, but prolongs stress-induced elevation of plasma corticosterone.
2019 Jan Diabetes Metab Efficacy and adherence of glucagon-like peptide-1 receptor agonist treatment in patients with type 2 diabetes mellitus in real-life settings.
2018 Kidney Int Suppl (2011) Cardiovascular outcomes in diabetic kidney disease: insights from recent clinical trials.
2019 Jan Diabetes Determining the Effects of Combined Liraglutide and Phentermine on Metabolic Parameters, Blood Pressure and Heart Rate in Lean and Obese Male Mice.
2019 Jan Diabetes Care Erratum. Renal effects of DPP-4 inhibitor sitagliptin or GLP-1 receptor agonist liraglutide in overweight patients with type 2 diabetes: a 12-week, randomized, double-blind, placebo-controlled trial. Diabetes Care 2016;39:2042-2050.
2019 Jan CEN Case Rep Two cases of advanced stage rapidly progressive diabetic nephropathy effectively treated with combination therapy including RAS blocker, GLP-1 receptor agonist and SGLT-2 inhibitor.
2019 Jan Lab Invest Glucagon-like peptide-1 receptor activation alleviates lipopolysaccharide-induced acute lung injury in mice via maintenance of endothelial barrier function.
2019 Expert Rev Clin Pharmacol Future perspectives of the pharmacological management of diabetic dyslipidemia.
2019 Jan Diabetes Res Clin Pract HM47118A, a novel insulinotropic GPR119 agonist and potential oral antidiabetic agent.
2019 Jan JAMA Neurol Utility of Neuronal-Derived Exosomes to Examine Molecular Mechanisms That Affect Motor Function in Patients With Parkinson Disease: A Secondary Analysis of the Exenatide-PD Trial.
2019 Jan J Mol Neurosci Combination of Insulin with a GLP1 Agonist Is Associated with Better Memory and Normal Expression of Insulin Receptor Pathway Genes in a Mouse Model of Alzheimer's Disease.
2019 Jan Diabetes Obes Metab Effects of lixisenatide on postprandial blood pressure, gastric emptying and glycaemia in healthy people and people with type 2 diabetes.
2019 Jan J Biol Chem Non-conventional glucagon and GLP-1 receptor agonist and antagonist interplay at the GLP-1 receptor revealed in high-throughput FRET assays for cAMP.
2018 Front Cell Neurosci Structural Changes Observed in the Piriform Cortex in a Rat Model of Pre-motor Parkinson's Disease.
2018 Front Neurosci Liraglutide Ameliorates β-Amyloid Deposits and Secondary Damage in the Ipsilateral Thalamus and Sensory Deficits After Focal Cerebral Infarction in Rats.
2019 Jan Diabetes Metab Comparative efficacy, safety, and cardiovascular outcomes with once-weekly cutaneous semaglutide in the treatment of type 2 diabetes: Insights from the SUSTAIN 1-7 trials.
2018 Dec Diabetes Metab J Asian Subpopulations May Exhibit Greater Cardiovascular Benefit from Long-Acting Glucagon-Like Peptide 1 Receptor Agonists: A Meta-Analysis of Cardiovascular Outcome Trials.
2019 Diabetes Ther A Summary of 2018 and What Lies Ahead for Diabetes Therapy in 2019.
2018 Diabetol Int Low body mass index and old age are useful in predicting the hemoglobin A1c-lowering effect of switching from sitagliptin to dulaglutide in Japanese patients with type 2 diabetes mellitus: a single-center, open-label, single-arm, pilot study.
2018 Dec World J Diabetes Effects of glucose-lowering agents on cardiorespiratory fitness.
2019 Jan J Control Release Long-term oral administration of Exendin-4 to control type 2 diabetes in a rat model.
2018 Rev Med Liege [Management of hyperglycaemia of type 2 diabetes. Paradigm change according to the ADA-EASD consensus report 2018].
2018 Dec Intern Med Suppression Failure of Cortisol Secretion by Dexamethasone May Occur in Glucagon-like Peptide-1 Receptor Agonist-treated Patients with Diabetic Autonomic Neuropathy.
2018 Dec Circulation Effects of Liraglutide Versus Placebo on Cardiovascular Events in Patients With Type 2 Diabetes Mellitus and Chronic Kidney Disease.
2018 Dec Diabetes Obes Metab Largest single-centre experience of dulaglutide for management of diabetes mellitus in solid organ transplant recipients.
2018 Dec Clin Pharmacokinet Safety and Pharmacokinetics of Single and Multiple Ascending Doses of the Novel Oral Human GLP-1 Analogue, Oral Semaglutide, in Healthy Subjects and Subjects with Type 2 Diabetes.
2018 Dec Curr Med Res Opin Impact of dose capping in insulin glarginelixisenatide fixed-ratio combination trials in patients with type 2 diabetes.
2018 Dec Cardiovasc Diabetol GLP-1RAs in type 2 diabetes: mechanisms that underlie cardiovascular effects and overview of cardiovascular outcome data.
2019 Diabetes Ther A Review of the Safety and Adverse Event Profile of the Fixed-Ratio Combination of Insulin Glargine and Lixisenatide.
2018 Diabetes Metab Syndr Obes Is there an association between liraglutide use and female breast cancer in a real-world setting?
2018 Eur Surg Res GLP1 Receptor Agonist Liraglutide Is an Effective Therapeutic Option for Perioperative Glycemic Control in Type 2 Diabetes within Enhanced Recovery After Surgery (ERAS) Protocols.
2018 Dec Diabetes Obes Metab Addition of glucagon-like peptide-1 receptor agonist therapy to insulin in C-peptide-positive patients with type 1 diabetes.
2019 Diabetes Ther Once-Weekly Semaglutide Versus Once-Daily Liraglutide for the Treatment of Type 2 Diabetes: A Long-Term Cost-Effectiveness Analysis in Estonia.
2018 Dec Endocrine Liraglutide induces beige fat development and promotes mitochondrial function in diet induced obesity mice partially through AMPK-SIRT-1-PGC1-α cell signaling pathway.
2018 Oxid Med Cell Longev Geniposide Protects against Obesity-Related Cardiac Injury through AMPKiαi- and Sirt1-Dependent Mechanisms.
2019 Feb J Endocrinol The key role of a glucagon-like peptide-1 receptor agonist in body fat redistribution.
2019 Diabetes Care Assessing the Association Between GLP-1 Receptor Agonist Use and Diabetic Retinopathy Through the FDA Adverse Event Reporting System.
2018 Dec Endocrinol Diabetes Nutr Liraglutide in a real-world setting: Joint modeling of metabolic response, prediction of efficacy, and cardiovascular risk.
2019 Lancet Diabetes Endocrinol Use of liraglutide and risk of major cardiovascular events: a register-based cohort study in Denmark and Sweden.
2018 Dec Diabetes Obes Metab Adherence, persistence, glycaemic control and costs among patients with type 2 diabetes initiating dulaglutide compared with liraglutide or exenatide once weekly at 12-month follow-up in a real-world setting in the United States.
2018 Dec J Diabetes Combined effect of GABA and glucagon-like peptide-1 receptor agonist on cytokine-induced apoptosis in pancreatic β-cell line and isolated human islets.
2018 Nov J Nucl Med Succinylated gelatin improves the theranostic potential of radiolabeled exendin-4 in insulinoma patients.
2019 J Diabetes Complications Targeting inflammation to reduce ASCVD in type 2 diabetes.
2018 Dec Nutrients Thromboxane-Dependent Platelet Activation in Obese Subjects with Prediabetes or Early Type 2 Diabetes: Effects of Liraglutide- or Lifestyle Changes-Induced Weight Loss.
2018 Diabetes Spectr Comparison of Usability, Accuracy, Preference, and Satisfaction Among Three Once-Weekly GLP-1 Receptor Agonist Pen Devices.
2018 Dec Sci Rep Engineering of a GLP-1 analogue peptideanti-PCSK9 antibody fusion for type 2 diabetes treatment.
2018 Nov Expert Opin Pharmacother Oral semaglutide for the treatment of type 2 diabetes.
2018 Nov Ann Pharmacother Adjunct Antihyperglycemic Agents in Overweight and Obese Adults With Type 1 Diabetes.
2018 Nov J Exp Clin Cancer Res GPR119 agonist enhances gefitinib responsiveness through lactate-mediated inhibition of autophagy.
2017 Dec Pharmacoeconomic Review R...
2018 Oct Diabetes Metab Effects of glucose-lowering agents on surrogate endpoints and hard clinical renal outcomes in patients with type 2 diabetes.
2018 Nov Diabetes Obes Metab Exenatide use and incidence of pancreatic and thyroid cancer: A retrospective cohort study.
2018 Mol Metab LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept.
2019 Mol Metab The aromatic amino acid sensor GPR142 controls metabolism through balanced regulation of pancreatic and gut hormones.
2019 Neuropeptides PYY(3-36) and exendin-4 reduce food intake and activate neuronal circuits in a synergistic manner in mice.
2019 Feb Biochim Biophys Acta Mol ... Evidence of metabolic memory-induced neurodegeneration and the therapeutic effects of glucagon-like peptide-1 receptor agonists via Forkhead box class O.
2019 Expert Opin Pharmacother Preventing and treating kidney disease in patients with type 2 diabetes.
2018 Front Endocrinol (Lausanne) Future Perspectives on GLP-1 Receptor Agonists and GLP-1glucagon Receptor Co-agonists in the Treatment of NAFLD.
2018 Nov Diabetes Obes Metab Liraglutide pharmacotherapy reduces body weight and improves glycaemic control in juvenile obesehyperglycaemic male and female rats.