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Recent literature: GLP-1 receptor agonist
Date Journal Article title
2020 Physiol Rep CCK-1 and CCK-2 receptor agonism do not stimulate GLP-1 and neurotensin secretion in the isolated perfused rat small intestine or GLP-1 and PYY secretion in the rat colon.
2020 Jan Diabetes Obes Metab Efficacy and Tolerability of Tirzepatide, a Dual GIP and GLP-1 Receptor Agonist in Patients with Type 2 Diabetes: A 12-Week, Randomised, Double-Blind, Placebo-Controlled Study to Evaluate Different Dose-Escalation Regimens.
2020 Jan Pharmacol Res Incretins and microRNAs: interactions and physiological relevance.
2020 Clin Diabetes Clinical Use of IDegLira: Initiation to Titration After Basal Insulin.
2020 Jan Mol Pharm Self-assembly of exendin-4 derived dual peptide agonists is mediated by acylation and correlated to length of conjugated fatty acyl chain.
2020 Neural Regen Res Exendin-4 attenuates pain-induced cognitive impairment by alleviating hippocampal neuroinflammation in a rat model of spinal nerve ligation.
2020 Jan Brain Behav The novel GLP-1GIP analogue DA5-CH reduces tau phosphorylation and normalizes theta rhythm in the icv. STZ rat model of AD.
2020 Jan Drugs Clinical Considerations When Initiating and Titrating Insulin DegludecLiraglutide (IDegLira) in People with Type 2 Diabetes.
2020 Jan J Parkinsons Dis The Novel Dual GLP-1GIP Receptor Agonist DA-CH5 Is Superior to Single GLP-1 Receptor Agonists in the MPTP Model of Parkinson's Disease.
2020 Clin Diabetes Endocrinol Achieving postprandial glucose control with lixisenatide improves glycemic control in patients with type 2 diabetes on basal insulin: a post-hoc analysis of pooled data.
2020 Jan Diabetes Metab Res Rev Efficacy of Exenatide and Insulin Glargine on Nonalcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus.
2020 Jan Prog Neuropsychopharmacol... The GLP-1 receptor agonist liraglutide reverses mania-like alterations and memory deficits induced by D-amphetamine and augments lithium effects in mice: Relevance for bipolar disorder.
2020 Jan J Diabetes Complications Oral semaglutide in type 2 diabetes.
2020 Jan Diabetes Care No Acute Effects of Exogenous Glucose-Dependent Insulinotropic Polypeptide on Energy Intake, Appetite, or Energy Expenditure When Added to Treatment With a Long-Acting Glucagon-Like Peptide 1 Receptor Agonist in Men With Type 2 Diabetes.
2020 Jan Biochem Biophys Res Commun Liraglutide promotes the angiogenic ability of human umbilical vein endothelial cells through the JAK2STAT3 signaling pathway.
2020 Jan Diabetes Obes Metab Comparison of two glucagon-like-peptide-1 analogs (GLP -1) dulaglutide vs liraglutide for the management of diabetes in solid organ transplant (SOT): a retrospective study.
2019 Cardiovasc Endocrinol Metab Cardioprotective diabetes drugs: what cardiologists need to know.
2020 Jan JCI Insight Tacrolimus- and sirolimus-induced human β cell dysfunction is reversible and preventable.
2020 Jan Sci Rep The nuclear receptor FXR inhibits Glucagon-Like Peptide-1 secretion in response to microbiota-derived Short-Chain Fatty Acids.
2020 Jan Ann Intern Med Assessing the Risk for Gout With Sodium-Glucose Cotransporter-2 Inhibitors in Patients With Type 2 Diabetes: A Population-Based Cohort Study.
2020 Jan Endocrine Efficacy and safety of long-acting glucagon-like peptide-1 receptor agonist dulaglutide in patients with type 2 diabetes: a systematic review and meta-analysis of 21 randomized controlled trials.
2020 Jan Diabetes Ther The Short-Term Cost-Effectiveness of Once-Weekly Semaglutide Versus Once-Daily Sitagliptin and Once-Weekly Dulaglutide for the Treatment of Patients with Type 2 Diabetes: A Cost of Control Analysis in Spain.
2020 Jan J Nucl Med Targeted optical imaging of the glucagon-like peptide 1 receptor using exendin-4-IRDye800CW.
2020 Jan Peptides CRISPRCas9 gene editing demonstrates metabolic importance of GPR55 in the modulation of GIP release and pancreatic beta cell function.
2020 Endocrinol Diabetes Metab Risk of any hypoglycaemia with newer antihyperglycaemic agents in patients with type 2 diabetes: A systematic review and meta-analysis.
2019 Diabetes Metab Syndr Obes Dulaglutide as an Add-on to Insulin in Type 2 Diabetes; Clinical Efficacy and Parameters Affecting the Response in Real-World Practice.
2020 Rev Med Liege [Which injectable therapy after failure of oral antidiabetic agents in type 2 diabetes ?]
2020 Nature Activation of the GLP-1 receptor by a non-peptidic agonist.
2020 Jan Int J Obes (Lond) Short-term GLP-1 receptor agonist exenatide ameliorates intramyocellular lipid deposition without weight loss in obob mice.
2019 Dec Int J Environ Res Public ... Long-Term Effectiveness of Liraglutide for Weight Management and Glycemic Control in Type 2 Diabetes.
2019 J Clin Exp Hepatol Antidiabetic Drugs and Statins in Nonalcoholic Fatty Liver Disease.
2019 Dec Curr Diabetes Rev Liraglutide therapy in a prediabetic state: Rethinking the evidence.
2019 Dec Bone Bone resorption is unchanged by liraglutide in type 2 diabetes patients: A randomised controlled trial.
2019 Dec BMC Cardiovasc Disord Targeting the DPP-4-GLP-1 pathway improves exercise tolerance in heart failure patients: a systematic review and meta-analysis.
2019 Dec Ophthalmic Res Exendin-4 Protects Human Retinal Pigment Epithelial Cells from H2O2-Induced Oxidative Damage via Activation of NRF2 Signaling.
2019 Dec Pharmacol Res Neuromodulatory effects of anti-diabetes medications: A mechanistic review.
2019 Dec Gynecol Endocrinol The effect of dipeptidyl peptidase-4 inhibitor and glucagon-like peptide-1 receptor agonist in gestational diabetes mellitus: a systematic review.
2020 Diabetes Care 2019 Update to: Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).
2019 Dec J Mol Endocrinol Activation of GLP-1 receptor enhances the chemosensitivity of pancreatic cancer cells.
2020 Diabetologia 2019 update to: Management of hyperglycaemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).
2019 Dec Nat Rev Drug Discov Advances in oral peptide therapeutics.
2019 Dec Peptides Recent advances of GIP and future horizons.
2019 Dec J Control Release A polyphenol-metal nanoparticle platform for tunable release of liraglutide to improve blood glycemic control and reduce cardiovascular complications in a mouse model of type II diabetes.
2020 Jan Life Sci Anti-inflammatory potentials of incretin-based therapies used in the management of diabetes.
2019 Oct Biol Psychiatry Ghrelin and Orexin Interact to Increase Meal Size Through a Descending Hippocampus to Hindbrain Signaling Pathway.
2020 Diabetes Ther Oral Semaglutide Versus Empagliflozin, Sitagliptin and Liraglutide in the UK: Long-Term Cost-Effectiveness Analyses Based on the PIONEER Clinical Trial Programme.
2019 Dec Cardiovasc Res Cardiovascular effects of GLP-1 receptor agonists: from mechanistic studies in humans to clinical outcomes.
2020 Mar Physiol Behav Phasic dopamine responses to a food-predictive cue are pressed by the glucagon-like peptide-1 receptor agonist Exendin-4.
2019 Dec Eur J Heart Fail European Society of CardiologyHeart Failure Association position paper on the role and safety of new glucose-lowering drugs in patients with heart failure.
2020 Jan Eur J Pharmacol Conservation of glucagon like peptide-1 level with liraglutide and linagilptin protects the kidney against angiotensin II-induced tissue fibrosis in rats.
2019 Dec J Diabetes Sci Technol The Differential and Combined Action of Insulin Glargine and Lixisenatide on the Fasting and Postprandial Components of Glucose Control.
2019 Dec Diabetes Obes Metab Dual glucagon-like peptide-1 receptorglucagon receptor agonist SAR425899 improves beta-cell function in type 2 diabetes.
2020 Diabetes Ther Metabolic Control and Adherence to Therapy in Type 2 Diabetes Mellitus Patients Using IDegLira in a Real-World Setting.
2019 Dec J Lipid Res Novel GPR120 agonist TUG891 modulates fat taste perception and preference and activates tongue-brain-gut axis in mice.
2019 Dec J Magn Reson Imaging Effect of Liraglutide on Cardiovascular Function and Myocardial Tissue Characteristics in Type 2 Diabetes Patients of South Asian Descent Living in the Netherlands: A Double-Blind, Randomized, Placebo-Controlled Trial.
2019 BMJ Open Diabetes Res Care Effectiveness, treatment durability, and treatment costs of canagliflozin and glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes in the USA.
2019 Dec Diabetes Obes Metab Effects of sequential treatment with lixisenatide, insulin glargine, or their combination on meal-related glycaemic excursions, insulin and glucagon secretion, and gastric emptying in patients with type 2 diabetes.
2020 Expert Opin Pharmacother An evaluation of liraglutide including its efficacy and safety for the treatment of obesity.
2019 Nov J Endocrinol Invest DR10601, a novel recombinant long-acting dual glucagon-like peptide-1 and glucagon receptor agonist for the treatment of obesity and type 2 diabetes mellitus.
2019 Nov J Neuroinflammation The glucagon-like peptide-1 receptor agonist reduces inflammation and blood-brain barrier breakdown in an astrocyte-dependent manner in experimental stroke.
2019 Nov Endocr J SGLT2 inhibitor ipragliflozin attenuates breast cancer cell proliferation.
2019 Cardiol Res Pract GLP-1 Relaxes Rat Coronary Arteries by Enhancing ATP-Sensitive Potassium Channel Currents.
2019 Nov Fluids Barriers CNS Preclinical update on regulation of intracranial pressure in relation to idiopathic intracranial hypertension.
2019 Eur J Prev Cardiol Glucose-lowering therapies in patients with type 2 diabetes and cardiovascular diseases.
2019 Nov Horm Behav A dual GLP-1 and Gcg receptor agonist rescues spatial memory and synaptic plasticity in APPPS1 transgenic mice.
2020 Jan Brain Res Alcohol-mediated behaviours and the gut-brain axis; with focus on glucagon-like peptide-1.
2019 J Comput Aided Mol Des Discovery of a potential positive allosteric modulator of glucagon-like peptide 1 receptor through virtual screening and experimental study.
2019 Circ Cardiovasc Interv Clinical Outcomes in Patients With Type 2 Diabetes Mellitus and Peripheral Artery Disease: Results From the EXSCEL Trial.
2019 Nov Diabetes Obes Metab Liraglutide for perioperative management of hyperglycaemia in cardiac surgery patients: a multicentre randomized eriority trial.
2019 Lancet Diabetes Endocrinol Research digest: pioneering an oral GLP-1 receptor agonist.
2019 Nov Ann Pharmacother Oral Semaglutide: First-in-Class Oral GLP-1 Receptor Agonist for the Treatment of Type 2 Diabetes Mellitus.
2019 Dec J Endocr Soc Optimal Glycemic Control in a Patient With HNF1A MODY With GLP-1 RA Monotherapy: Implications for Future Therapy.
2019 Diabetes Res Clin Pract Glycemic efficacy and safety of glucagon-like peptide-1 receptor agonist on top of sodium-glucose co-transporter-2 inhibitor treatment compared to sodium-glucose co-transporter-2 inhibitor alone: A systematic review and meta-analysis of randomized controlled trials.
2020 Exp Neurol Neurotrophic and neuroprotective effects of a monomeric GLP-1GIPGcg receptor triagonist in cellular and rodent models of mild traumatic brain injury.
2020 Jan Am J Physiol Heart Circ P... The glucagon-like peptide 1 receptor agonist liraglutide attenuates placental ischemia-induced hypertension.