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Recent literature: GLP-1 receptor agonist
Date Journal Article title
2019 Apr J Cachexia Sarcopenia Muscle Amelioration of muscle wasting by glucagon-like peptide-1 receptor agonist in muscle atrophy.
2019 Ann Transl Med Long-acting glucagon-like peptide-1 receptor agonist-status December 2018.
2019 Obes Sci Pract Effect of liraglutide on anthropometric measurements, sagittal abdominal diameter and adiponectin levels in people with type 2 diabetes treated with multiple daily insulin injections: evaluations from a randomized trial (MDI-liraglutide study 5).
2019 Apr Neuropharmacology Topical ocular administration of the GLP-1 receptor agonist liraglutide arrests hyperphosphorylated tau-triggered diabetic retinal neurodegeneration via activation of GLP-1RAktGSK3β signaling.
2019 Apr Diabetes Care Changes in Serum Calcitonin Concentrations, Incidence of Medullary Thyroid Carcinoma, and Impact of Routine Calcitonin Concentration Monitoring in the EXenatide Study of Cardiovascular Event Lowering (EXSCEL).
2019 Apr Diabetes Res Clin Pract Efficacy and Safety of an Albiglutide Liquid Formulation Compared With the Lyophilized Formulation: A 26-Week Randomized, Double-Blind, Repeat-Dose Study in Patients With Type 2 Diabetes Mellitus.
2019 Rev Med Liege [Basal insulin degludec (Tresiba®)].
2019 Chronic Dis Transl Med Advances in reducing cardiovascular risk in the management of patients with type 2 diabetes mellitus.
2019 Am J Manag Care Authors' reply to "Comment on generalizability of GLP-1 RA CVOTs in US T2D population".
2019 Apr IUBMB Life The GLP1 Receptor Agonist Liraglutide Protects Against Oxidized LDL-Induced Endothelial Inflammation and Dysfunction via KLF2.
2019 Apr Gastroenterology Remission of bile acid malabsorption symptoms following treatment with the glucagon-like peptide 1 receptor agonist liraglutide.
2019 Clinicoecon Outcomes Res Cost of achieving HbA1c and weight loss treatment targets with IDegLira vs insulin glargine U100 plus insulin aspart in the USA.
2019 Apr J Clin Endocrinol Metab Effect of the GLP-1 receptor agonist exenatide on impaired awareness of hypoglycemia in type 1 diabetes; a randomized controlled trial.
2019 Apr J Neuroinflammation Highly glycosylated CD147 promotes hemorrhagic transformation after rt-PA treatment in diabetes: a novel therapeutic target?
2019 Apr Sci Rep Evaluation of [68Ga]DO3A-VS-Cys40-Exendin-4 as a PET Probe for Imaging Human Transplanted Islets in the Liver.
2019 Apr Obes Res Clin Pract Protective effects of liraglutide on glomerular podocytes in obese mice by inhibiting the inflammatory factor TNF-α-mediated NF-κB and MAPK pathway.
2019 Apr Neuropharmacology GLP-1dexamethasone inhibits food reward without inducing mood and memory deficits in mice.
2019 Apr Physiol Behav The effect of glucagon-like PEPTIDE-1 (GLP-1) receptor agonists on stance use disorder (SUD)-related behavioural effects of drugs and alcohol: A systematic review.
2019 J Diabetes Res Predictors of Effectiveness of Glucagon-Like Peptide-1 Receptor Agonist Therapy in Patients with Type 2 Diabetes and Obesity.
2019 Mar Int J Mol Sci Dulaglutide Modulates the Development of Tissue-Infiltrating Th1Th17 Cells and the Pathogenicity of Encephalitogenic Th1 Cells in the Central Nervous System.
2019 Mar Ugeskr Laeger [Glucagon-like peptide 1 receptor agonists for the treatment of Type 2 diabetes].
2019 Korean J Fam Med Understanding the Mechanism of Action and Clinical Implications of Anti-Obesity Drugs Recently Approved in Korea.
2019 J Diabetes Res Glucagon-Like Peptide-1 Receptor Agonist Protects Dorsal Root Ganglion Neurons against Oxidative Insult.
2019 Mar Diabetes Ther Safety and Efficacy of Empagliflozin as Add-On Therapy to GLP-1 Receptor Agonist (Liraglutide) in Japanese Patients with Type 2 Diabetes Mellitus: A Randomised, Double-Blind, Parallel-Group Phase 4 Study.
2019 Mar J Pharmacol Exp Ther Liraglutide improves renal endothelial function in obese Zucker rats on a high-salt diet.
2019 Mar JAMA Effect of Additional Oral Semaglutide vs Sitagliptin on Glycated Hemoglobin in Adults With Type 2 Diabetes Uncontrolled With Metformin Alone or With Sulfonylurea: The PIONEER 3 Randomized Clinical Trial.
2019 Mar IUBMB Life Exenatide Ameliorates Inflammatory Response in Human Rheumatoid Arthritis Fibroblast-Like Synoviocytes.
2019 Mar J Manag Care Spec Pharm The Effect of Early Response to GLP-1 RA Therapy on Long-Term Adherence and Persistence Among Type 2 Diabetes Patients in the United States.
2019 Mar Biochem Pharmacol The osteogenic effect of liraglutide involves enhanced mitochondrial biogenesis in osteoblasts.
2019 Mar Diabetes Ther Hypoglycemia Abrogates the Vascular Endothelial Protective Effect of Exenatide in Type 2 Diabetes Mellitus.
2019 Mar Brain Res Bull Inhibitory effects of peripheral administration of exendin-4 on food intake are attenuated by lesions of the central nucleus of amygdala.
2019 Mar Am J Physiol Endocrinol M... Anti-atherogenic effects of liraglutide in hyperglycemic apolipoprotein E-null mice via AMP-activated protein kinase independent mechanisms.
2019 Adv Ther The Role of Glucagon-Like Peptide-1 Receptor Agonists in Type 2 Diabetes in Asia.
2019 Mar Diabetes Obes Metab Longitudinal changes in glycated haemoglobin following treatment intensification after inadequate response to two oral antidiabetic agents in patients with type 2 diabetes.
2019 Mar Diabetes Obes Metab Gastrin analogue administration adds no significant glycaemic benefit to a glucagon-like peptide-1 receptor agonist acutely or after washout of both analogues.
2019 Diabetes Ther Patient Preferences for GLP-1 Receptor Agonist Treatment of Type 2 Diabetes Mellitus in Japan: A Discrete Choice Experiment.
2019 Biomed Pharmacother Biochemical and histological characterisation of an experimental rodent model of non-alcoholic steatohepatitis - Effects of a peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist and a glucagon-like peptide-1 analogue.
2019 Front Nutr Peptides and Peptidomimetics as Potential Antiobesity Agents: Overview of Current Status.
2019 Expert Opin Drug Discov Exciting advances in GPCR-based drugs discovery for treating metabolic disease and future perspectives.
2019 J Manag Care Spec Pharm Evaluation of Outcomes After Initiating Triple Antidiabetic Therapy with a GLP-1 RA in an Integrated Health Care System.
2019 Endocrinol Diabetes Metab Real-world GLP-1 RA therapy in type 2 diabetes: A long-term effectiveness observational study.
2018 Endocrinol Diabetes Metab Glucose lowering and vascular protective effects of cycloset added to GLP-1 receptor agonists in patients with type 2 diabetes.
2018 Endocrinol Diabetes Metab Glycaemic impact of treatment intensification in patients with type 2 diabetes uncontrolled with oral antidiabetes drugs or basal insulin.
2019 Front Endocrinol (Lausanne) The GLP-1 Receptor Agonist Exenatide Ameliorates Bone Composition and Tissue Material Properties in High Fat Fed Diabetic Mice.
2019 Physiol Rep The impact of the glucagon-like peptide 1 receptor agonist liraglutide on the streptozotocin-induced diabetic mouse kidney proteome.
2019 Feb Metabolism Beyond glycemic control: New guidance on cardio-renal protection.
2019 Feb Molecules Novel Site-Specific Fatty Chain-Modified GLP-1 Receptor Agonist with Potent Antidiabetic Effects.
2019 Rev Med Liege [Basal insulin glargine-lixisenatide fixed ratio combination (Suliqua®)].
2019 Feb Int J Mol Sci Glucagon-Like Peptide-1 (GLP-1) and 5-Hydroxytryptamine 2c (5-HT2c) Receptor Agonists in the Ventral Tegmental Area (VTA) Inhibit Ghrelin-Stimulated Appetitive Reward.
2019 Diabetes Ther C-Peptide Area Under the Curve at Glucagon Stimulation Test Predicts Glucose Improvements by GLP-1 Receptor Analogue: A Retrospective Observational Study.
2019 Exp Mol Pathol GLP-1 receptor agonist impairs keratinocytes inflammatory signals by activating AMPK.
2019 Apr Cell Metab A Long-Acting PYY3-36 Analog Mediates Robust Anorectic Efficacy with Minimal Emesis in Nonhuman Primates.
2019 Mar Biochem Biophys Res Commun Dulaglutide ameliorates STZ induced AD-like impairment of learning and memory ability by modulating hyperphosphorylation of tau and NFs through GSK3β.
2019 J Diabetes Complications Liraglutide prevents β-cell apoptosis via inactivation of NOX2 and its related signaling pathway.
2019 Feb EJNMMI Res First-in-class positron emission tomography tracer for the glucagon receptor.
2019 May Eur J Pharmacol The effect of exenatide (a GLP-1 analog) and sitagliptin (a DPP-4 inhibitor) on plasma platelet-activating factor acetylhydrolase (PAF-AH) activity and concentration in normal and fructose-fed rats.
2019 Feb Obes Rev Semaglutide as a promising antiobesity drug.
2018 Front Psychiatry Bone Status in Obese, Non-diabetic, Antipsychotic-Treated Patients, and Effects of the Glucagon-Like Peptide-1 Receptor Agonist Exenatide on Bone Turnover Markers and Bone Mineral Density.
2019 J Parkinsons Dis Semaglutide is Neuroprotective and Reduces α-Synuclein Levels in the Chronic MPTP Mouse Model of Parkinson's Disease.
2019 Feb Diabetes Obes Metab Evaluating the long-term cost-effectiveness of fixed-ratio combination insulin degludecliraglutide (IDegLira) for type 2 diabetes in Spain based on real-world clinical evidence.
2019 Feb J Am Acad Dermatol Reply to: Comment on "Oral diabetes medications other than dipeptidyl peptidase-4 inhibitors are not associated with bullous pemphigoid: A Finnish nationwide case control study" and a case report of glucagon-like peptide-1 receptor agonist induced bullous pemphigoid.
2019 Expert Opin Pharmacother The efficacy and safety of exenatide once weekly in patients with type 2 diabetes.
2019 Feb J Manag Care Spec Pharm Effect of Weight Change on Economic Outcomes Among Persons with Type 2 Diabetes Mellitus in the United States: Beyond Glycemic Control.
2019 Feb Diabetes Obes Metab Generalizability of glucagon-like peptide-1 receptor agonist cardiovascular outcome trials to the overall type 2 diabetes population in the United States.
2019 Jan Prim Care Diabetes Network meta-analysis of nine large cardiovascular outcome trials of new antidiabetic drugs.
2018 Jun Ter Arkh Renal effects of glucagon-like peptide receptor agonists in patients with type 1 diabetes mellitus.
2019 Jan Endocr Connect Incretin-based therapies for patients with type 1 diabetes: a meta-analysis.
2019 Diabetes Obes Metab FDA guidance on antihyperglyacemic therapies for type 2 diabetes: One decade later.
2019 Horm Metab Res Exenatide Delays Gastric Emptying in Patients with Type 2 Diabetes Mellitus but not in Those with Gastroparetic Conditions.
2019 Mol Metab GDF15 acts synergistically with liraglutide but is not necessary for the weight loss induced by bariatric surgery in mice.
2019 Diabetologia Effects of combined GIP and GLP-1 infusion on energy intake, appetite and energy expenditure in overweightobese individuals: a randomised, crossover study.
2019 Apr J Neurosci Chronic Suppression of Glucagon-Like Peptide-1 Receptor (GLP1R) mRNA Translation in the Rat Bed Nucleus of the Stria Terminalis Reduces Anxiety-Like Behavior and Stress-Induced Hypophagia, But Prolongs Stress-Induced Elevation of Plasma Corticosterone.
2019 Jan Diabetes Metab Efficacy and adherence of glucagon-like peptide-1 receptor agonist treatment in patients with type 2 diabetes mellitus in real-life settings.
2018 Kidney Int Suppl (2011) Cardiovascular outcomes in diabetic kidney disease: insights from recent clinical trials.