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Recent literature: GLP-1 receptor agonist
Date Journal Article title
2019 Dec J Endocr Soc Optimal Glycemic Control in a Patient With HNF1A MODY With GLP-1 RA Monotherapy: Implications for Future Therapy.
2019 Nov Diabetes Res Clin Pract Glycemic efficacy and safety of glucagon-like peptide-1 receptor agonist on top of sodium-glucose co-transporter-2 inhibitor treatment compared to sodium-glucose co-transporter-2 inhibitor alone: a systematic review and meta-analysis of randomized controlled trials.
2019 Nov Exp Neurol Neurotrophic and neuroprotective effects of a monomeric GLP-1GIPGcg receptor triagonist in cellular and rodent models of mild traumatic brain injury.
2019 Nov Am J Physiol Heart Circ P... The glucagon-like peptide 1 receptor agonist liraglutide attenuates placental-ischemia induced hypertension.
2019 Nov Coron Artery Dis Effect of semaglutide on coronary atherosclerosis progression in patients with type II diabetes: rationale and design of the semaglutide treatment on coronary progressiontrial.
2019 Nov Curr Opin Nephrol Hypertens Renoprotection in diabetic kidney disease: can incretin-based therapies deliver?
2019 Front Pharmacol GLP-1 Receptor Activation Abrogates β-Cell Dysfunction by PKA Cα-Mediated Degradation of Thioredoxin Interacting Protein.
2019 Nov Peptides GIP has neuroprotective effects in Alzheimer and Parkinson's disease models.
2019 Nov Diabetes Metab J Glucagon-Like Peptide-1 Receptor Agonist Differentially Affects Brain Activation in Response to Visual Food Cues in Lean and Obese Individuals with Type 2 Diabetes Mellitus.
2019 Nov Sci Rep The beneficial effects of a muscarinic agonist on pancreatic β-cells.
2019 Nov Diabetes Obes Metab Liraglutide reduces hyperglycaemia and body weight in overweight, dysregulated insulin-pump-treated patients with type 1 diabetes: The Lira Pump trial - a randomized, double-blinded, placebo-controlled trial.
2019 Nov Diabet Med Intensive monitoring of adverse drug events associated with the use of new glucose-lowering drugs: results from an inception cohort study in Portugal.
2019 Nov Diabetologia Placebo-controlled randomised trial with liraglutide on magnetic resonance endpoints in individuals with type 2 diabetes: a pre-specified secondary study on ectopic fat accumulation.
2019 Drug Des Devel Ther The development of an oral GLP-1 receptor agonist for the management of type 2 diabetes: evidence to date.
2019 Nov Int Immunopharmacol Glucagon-like peptide-1 receptor agonist exendin-4 mitigates lipopolysaccharide-induced inflammatory responses in RAW264.7 macrophages.
2019 Nov BMJ Open Protocol for a randomised controlled trial of the combined effects of the GLP-1 receptor agonist liraglutide and exercise on maintenance of weight loss and health after a very low-calorie diet.
2019 Oct Sci Rep GLP-1 receptor agonist liraglutide has a neuroprotective effect on an aged rat model of Wolfram syndrome.
2019 Oct Curr Drug Targets An overview of prospective drugs for type 1 and type 2 diabetes.
2019 Oct Sci Rep Metabolic and gut microbiome changes following GLP-1 or dual GLP-1GLP-2 receptor agonist treatment in diet-induced obese mice.
2019 Neurochem Int Mechanism of the neuroprotective effect of GLP-1 in a rat model of Parkinson's with pre-existing diabetes.
2019 Adv Ther Evaluation of the Cost Per Patient Achieving Treatment Targets with Oral Semaglutide: A Short-Term Cost-Effectiveness Analysis in the United States.
2019 Adv Ther Combining GLP-1 Receptor Agonists and Basal Insulin in Older Adults with Type 2 Diabetes: Focus on Lixisenatide and Insulin Glargine.
2012 LiverTox: Clinical and Re... Weight Loss Agents
2012 LiverTox: Clinical and Re... Glucagon-Like Peptide-1 (GLP-1) Analogues
2019 BMJ Open Diabetes Res Care Once-weekly semaglutide for patients with type 2 diabetes: a cost-effectiveness analysis in the Netherlands.
2019 BMJ Open Diabetes Res Care Addition of a single short-acting insulin bolus to basal insulin-ported oral therapy: a systematic review of data on the basal-plus regimen.
2019 Oct Cardiovasc Diabetol Effects of exenatide and open-label SGLT2 inhibitor treatment, given in parallel or sequentially, on mortality and cardiovascular and renal outcomes in type 2 diabetes: insights from the EXSCEL trial.
2019 Oct Diabetes Obes Metab Oral semaglutide for type 2 diabetes: a systematic review and meta-analysis.
2019 Oct Endocrinology Non-invasive evaluation of GPR119 agonist effects on β-cell mass in diabetic male mice using 111In-exendin-4 SPECTCT.
2019 Oct J Clin Endocrinol Metab Gluco-metabolic effects of pharmacotherapy-induced modulation of bile acid physiology.
2019 Oct Mol Immunol Glucagon-like peptide-1 receptor agonist dulaglutide prevents ox-LDL-induced adhesion of monocytes to human endothelial cells: An implication in the treatment of atherosclerosis.
2019 Oct Neuropharmacology Neuroprotective and restorative properties of the GLP-1GIP dual agonist DA-JC1 compared with a GLP-1 single agonist in Alzheimer's disease.
2019 Oct Sci Rep Assessment of glucagon receptor occupancy by Positron Emission Tomography in non-human primates.
2019 Dec Endocrinology Noninvasive Evaluation of GPR119 Agonist Effects on β-Cell Mass in Diabetic Male Mice Using 111In-Exendin-4 SPECTCT.
2019 Oct J Med Econ Assessing the cost-effectiveness of a once-weekly GLP-1 analogue versus an SGLT-2 inhibitor in the Spanish setting: Once-weekly semaglutide versus empagliflozin.
2019 Oct J Am Pharm Assoc (2003) Real-world impact on monthly glucose-lowering medication cost, HbA1c, weight, and polytherapy after initiating a GLP-1 receptor agonist.
2019 Oct Ugeskr Laeger [The glucagon-like peptide-1 receptor-agonist semaglutide].
2019 Oct J Clin Endocrinol Metab Efficacy, safety, and mechanistic insights of cotadutide a dual receptor glucagon-like peptide-1 and glucagon agonist.
2019 Oct Diabetes Obes Metab Impact of baseline characteristics and beta-cell function on the efficacy and safety of cutaneous once-weekly semaglutide: A patient-level, pooled analysis of the SUSTAIN 1-5 trials.
2019 Oct Diabetes Metab Efficacy of semaglutide versus liraglutide in clinical practice.
2019 Diabetes Ther Efficacy of Dulaglutide as a First Injectable Option for Patients with Type 2 Diabetes: A Post-Hoc Pooled Analysis.
2019 Oct Neurogastroenterol Motil The Glucagon-like peptide-1 receptor agonist, exendin-4, ameliorated gastrointestinal dysfunction in the Wistar Kyoto rat model of Irritable Bowel Syndrome.
2019 Oct Eur J Endocrinol MANAGEMENT OF ENDOCRINE DISEASE: Are all GLP-1 agonist equal in the treatment of type 2 diabetes?
2019 Diabetes Ther Orally Administered Semaglutide Versus GLP-1 RAs in Patients with Type 2 Diabetes Previously Receiving 1-2 Oral Antidiabetics: Systematic Review and Network Meta-Analysis.
2019 Dec Endocrinology Effect of GLP-1 Receptor Agonists in the Cardiometabolic Complications in a Rat Model of Postmenopausal PCOS.
2019 Oct J Clin Endocrinol Metab Glucagon-like peptide 1 receptor agonists, diabetic retinopathy and angiogenesis: The AngioSafe type 2 diabetes study.
2019 Oct Neuropsychopharmacology Activation of GLP-1 receptors attenuates oxycodone taking and seeking without compromising the antinociceptive effects of oxycodone in rats.
2019 Dec J Biotechnol Mono-PEGylates of exenatide in branched and dimeric structures can improve in vivo stability and hypoglycemic bioactivity.
2019 Diabetol Metab Syndr Consensus recommendations for management of patients with type 2 diabetes mellitus and cardiovascular diseases.
2019 Sep Neuropharmacology Endocrine effects of the novel ghrelin receptor inverse agonist PF-5190457: Results from a placebo-controlled human laboratory alcohol co-administration study in heavy drinkers.
2019 Lancet Diabetes Endocrinol Efficacy and safety of once-weekly semaglutide versus daily canagliflozin as add-on to metformin in patients with type 2 diabetes (SUSTAIN 8): a double-blind, phase 3b, randomised controlled trial.
2019 Lancet Diabetes Endocrinol SGLT2 inhibitor or GLP-1 receptor agonist in type 2 diabetes?
2019 Sep Int J Mol Sci Liraglutide Inhibits Hepatitis C Virus Replication Through an AMP Activated Protein Kinase Dependent Mechanism.
2019 Sep Diabetes Metab Efficacy and safety of once-weekly semaglutide 1.0 mg vs once-daily liraglutide 1.2 mg as add-on to 1-3 oral antidiabetic drugs in jects with type 2 diabetes (SUSTAIN 10).
2020 Jan Mol Cell Endocrinol A long-acting, dual-agonist analogue of lamprey GLP-1 shows potent insulinotropic, β-cell protective, and anorexic activities and improves glucose homeostasis in high fat-fed mice.
2019 Sep Comb Chem High Throughput... Screening GLP-1 Receptor Ligands from Natural Products in Herbs through High-Content Technique.
2019 Sep Sci Rep Central Glucagon-like Peptide-1 Receptor Signaling via Brainstem Catecholamine Neurons Counteracts Hypertension in Spontaneously Hypertensive Rats.
2019 Oct JCI Insight Exenatide regulates pancreatic islet integrity and insulin sensitivity in the nonhuman primate baboon Papio hamadryas.
2019 Int Urol Nephrol Liraglutide promotes autophagy by regulating the AMPKmTOR pathway in a rat remnant kidney model of chronic renal failure.
2019 Diabetes Care Switching to iGlarLixi Versus Continuing Daily or Weekly GLP-1 RA in Type 2 Diabetes Inadequately Controlled by GLP-1 RA and Oral Antihyperglycemic Therapy: The LixiLan-G Randomized Clinical Trial.
2019 Sep J Diabetes Investig Role of incretin-based therapy in hospitalized patients with type 2 diabetes.
2019 Oct J Endocr Soc Dipeptidyl Peptidase 4 Inhibition Increases Postprandial Norepinephrine via Substance P (NK1 Receptor) During RAAS Inhibition.
2019 PLoS One GPR40 full agonism exerts feeding pression and weight loss through afferent vagal nerve.
2019 Aug World J Diabetes Development of therapeutic options on type 2 diabetes in years: Glucagon-like peptide-1 receptor agonist's role intreatment; from the past to future.
2019 Sep J Diabetes Investig Efficacy and safety of once-weekly exenatide after switching from twice-daily exenatide in patients with type 2 diabetes.
2019 Curr Alzheimer Res A Pilot Study of Exenatide Actions in Alzheimer's Disease.
2019 Am J Transl Res Liraglutide presses TNF-α-induced degradation of extracellular matrix in human chondrocytes: a therapeutic implication in osteoarthritis.
2019 Drug Des Devel Ther Liraglutide attenuates cardiac remodeling and improves heart function after abdominal aortic constriction through blocking angiotensin II type 1 receptor in rats.
2019 Rev Med Liege [Semaglutide, once weekly GLP-1 receptor agonist (Ozempic®)].
2019 Rev Med Liege [How I manage a patient with type 2 diabetes not well controlled with a metformin plus gliptin combination].
2019 Jul Domest Anim Endocrinol A once-monthly GLP-1 receptor agonist for treatment of diabetic cats.
2019 Brain Res Bull Evaluation of the effects of liraglutide on the development of epilepsy and behavioural alterations in two animal models of epileptogenesis.
2019 Mol Metab Direct and indirect effects of liraglutide on hypothalamic POMC and NPYAgRP neurons - Implications for energy balance and glucose control.
2019 Aug Int J Mol Sci The Effects of Dual GLP-1GIP Receptor Agonism on Glucagon Secretion-A Review.