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Recent literature: COX inhibitor
Date Journal Article title
2019 Feb Eur J Med Chem Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase.
2019 PLoS One Ornithine decarboxylase antizyme inhibitor 2 (AZIN2) is a signature of secretory phenotype and independent predictor of adverse prognosis in colorectal cancer.
2019 Feb ACS Appl Mater Interfaces Facile Engineering Indomethacin Induced Paclitaxel Nanocrystal Aggregates as Carrier-Free Nanomedicine with Improved Synergetic Antitumor Activity.
2019 Feb Vet Comp Oncol The selective cyclooxygenase-2 inhibitor mavacoxib (Trocoxcil™) exerts anti-tumour effects in-vitro independent of cyclooxygenase-2 expression levels.
2018 Cancer Biol Med Prognostic factors of refractory NSCLC patients receiving anlotinib hydrochloride as the third- or further-line treatment.
2019 Feb Bioorg Chem Anti-inflammatory drug approach: Synthesis and biological evaluation of novel pyrazolo[3,4-d]pyrimidine compounds.
2019 Feb J Chem Inf Model Classification of Cyclooxygenase-2 Inhibitors using Support Vector Machine and Random Forest Methods.
2019 Feb Mol Cell Endocrinol Galectin-3 plays an important role in endometriosis development and is a target to endometriosis treatment.
2018 Nov Am Surg Serotonin-Modulating Antidepressants and Risk of Bleeding after Trauma.
2019 Feb Nutrients Beta-Cryptoxanthin Inhibits Lipopolysaccharide-Induced Osteoclast Differentiation and Bone Resorption via the Suppression of Inhibitor of NF-κB Kinase Activity.
2019 PLoS One Second-line glucose-lowering drugs added to metformin and the risk of hospitalization for heart failure: A nationwide cohort study.
2019 Feb Acta Neurol Scand Statins and the risk of bleeding in patients taking dabigatran.
2019 Feb J Vet Pharmacol Ther Pharmacokinetics of the novel COX-2 selective inhibitor vitacoxib in cats: The effects of feeding and dose.
2019 Feb Reg Anesth Pain Med Intravenous meloxicam for the treatment of moderate to severe acute pain: a pooled analysis of safety and opioid-reducing effects.
2019 Feb FASEB J Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome.
2019 Evid Based Complement Alt... Downregulation of Aquaporin 3 Mediated the Laxative Effect in the Rat Colon by a Purified Resin Glycoside Fraction from Pharbitis Semen.
2019 Feb Leuk Lymphoma Risk factors for the development of atrial fibrillation on ibrutinib treatment.
2019 Feb Life Sci Protective effects of febuxostat against paraquat-induced lung toxicity in rats: Impact on RAGEPI3KAkt pathway and downstream inflammatory cascades.
2019 Feb Invest New Drugs Clinical outcomes of advanced stage cancer patients treated with sequential immunotherapy in phase 1 clinical trials.
2019 Feb Pharmacoepidemiol Drug Saf Use of dipeptidyl peptidase-4 inhibitors and the risk of arthralgia: Population-based cohort and nested case-control studies.
2019 Feb J Glaucoma Long Term Side effects Including Blepharitis Leading to Discontinuation of Ripasudil.
2019 Ther Adv Hematol A real-world comparative analysis of carfilzomib and other systemic multiple myeloma chemotherapies in a US community oncology setting.
2019 Feb Cancer Lett 3,3'-Diindolylmethane inhibits patient-derived xenograft colon tumor growth by targeting COX12 and ERK12.
2019 Feb Rheumatology (Oxford) Structural efficacy of NSAIDs, COX-2 inhibitor and glucocorticoid compared with TNFα blocker: a study in adjuvant-induced arthritis rats.
2019 Jan World Neurosurg EGFR mutation status confers survival benefit in non-small cell lung cancer patients undergoing surgical resection of brain metastases: a retrospective cohort study.
2019 Jan Eur J Pharmacol Mechanisms underlying vascular hypocontractility induced by ethanol withdrawal: Role of cyclooxygenase 2-derived prostacyclin.
2019 Feb Curr Med Chem Current anti-inflammatory therapies and the potential of secretory Phospholipase A2 inhibitors in the design of new anti-inflammatory drugs: a review of 2012 - 2018.
2019 Feb Clin Sci (Lond) Activation of G protein-coupled estrogen receptor protects intestine from ischemiareperfusion injury in mice by protecting the crypt cell proliferation.
2019 Circ Cardiovasc Interv Association of International Normalized Ratio Stability and Bleeding Outcomes Among Atrial Fibrillation Patients Undergoing Percutaneous Coronary Intervention.
2019 Jan Pharmacology Impact of Different Pharmacotherapies on Long-Term Outcomes in Patients with Electrical Storm.
2019 Jan Eur J Pharmacol The relatively selective cyclooxygenase-2 inhibitor nimesulide: What's going on?
2019 HIV Med Discontinuation of dolutegravir, elvitegravircobicistat and raltegravir because of toxicity in a prospective cohort.
2019 Jan Int J Cardiol Heart rate reduction strategy using ivabradine in end-stage Duchenne cardiomyopathy.
2019 JBMR Plus Manipulation of the Alternative NF-κB Pathway in Mice Has Sexually Dimorphic Effects on Bone.
2018 Dec Clin Lung Cancer Clinical Relevance of EGFR- or KRAS-mutated Subclones in Patients With Advanced Non-small-cell Lung Cancer Receiving Erlotinib in a French Prospective Cohort (IFCT ERMETIC2 Cohort - Part 2).
2018 Dec Domest Anim Endocrinol Effects of arachidonic acid and its major prostaglandin derivatives on bovine myoblast proliferation, differentiation, and fusion.
2019 J Hypertens Effect of antihypertensive therapy on development of incident conduction system disease in hypertensive patients.
2019 NPJ Breast Cancer MONARCH 3 final PFS: a randomized study of abemaciclib as initial therapy for advanced breast cancer.
2019 Jan J Nephrol Cyclooxygenase 2 inhibition slows disease progression and improves the altered renal lipid mediator profile in the Pkd2WS25- mouse model of autosomal dominant polycystic kidney disease.
2019 Jan Int J Mol Sci HADC8 Inhibitor WK2-16 Therapeutically Targets Lipopolysaccharide-Induced Mouse Model of Neuroinflammation and Microglial Activation.
2019 Jan Aging (Albany NY) DNA methylation GrimAge strongly predicts lifespan and healthspan.
2018 Aug Phytomedicine Anti-inflammation action of xanthones from Swertia chirayita by regulating COX-2NF-κBMAPKsAkt signaling pathways in RAW 264.7 macrophage cells.
2018 Sep Phytomedicine The anti-inflammatory and anti-nociceptive effects of Korean black ginseng.
2019 Mar J Endocrinol Inhibition of TPPP3 attenuates β-cateninNF-κBCOX-2 signaling in endometrial stromal cells and impairs decidualization.
2019 Jan Cancer Immunol Immunother Immune checkpoint inhibitor-induced colitis as a predictor of survival in metastatic melanoma.
2019 Mol Med Rep Sodium azide induces mitochondria‑mediated apoptosis in PC12 cells through Pgc‑1α‑associated signaling pathway.
2019 Jan Melanoma Res Overall survival after treatment for metastatic uveal melanoma: a systematic review and meta-analysis.
2019 Jan J Labelled Comp Radiopharm Access to 18 F-labelled isoxazoles by ruthenium-promoted 1,3-dipolar cycloaddition of 4-[18 F]fluoro-N-hydroxybenzimidoyl chloride with alkynes.
2018 Am J Transl Res Tepoxalin a dual 5-LOX-COX inhibitor and erlotinib an EGFR inhibitor halts progression of gastric cancer in tumor xenograft mice.
2019 Prostaglandins Leukot Ess... Interleukin-1β and prostaglandin-synthesizing enzymes as modulators of human omental and cutaneous adipose tissue function.
2019 Jan Clin Transl Med EGFR plasma mutation in prediction models for resistance with EGFR TKI and survival of non-small cell lung cancer.
2019 Jan Int J Biol Macromol The anticancer properties and mechanism of action of tablysin-15, the RGD-containing disintegrin, in breast cancer cells.
2019 Jan J Neurosurg Overall survival and response to radiation and targeted therapies among patients with renal cell carcinoma brain metastases.
2019 Jan J Cell Biochem miR-98 acts as an inhibitor in chronic constriction injury-induced neuropathic pain via downregulation of high-mobility group AT-hook 2.
2019 Jan Breast Cancer Res Treat Aromatase inhibitor and tamoxifen use and the risk of venous thromboembolism in breast cancer survivors.
2019 Jan Rheumatology (Oxford) Impact of TNF inhibitor therapy on joint replacement rates in rheumatoid arthritis: a matched cohort analysis of BSRBR-RA UK registry data.
2019 Jan Proc Natl Acad Sci U S A Suppression of chemotherapy-induced cytokinelipid mediator surge and ovarian cancer by a dual COX-2sEH inhibitor.
2019 Jan J Am Heart Assoc ThromboticThrombolytic Balance as a Cardiac Treatment Determinant in Patients With Diabetes Mellitus and Coronary Artery Disease.
2019 Jan Eur Radiol Development and validation of a prognostic index for efficacy evaluation and prognosis of first-line chemotherapy in stage III-IV lung squamous cell carcinoma.
2019 Jan J Prosthodont Relationship between Selective Serotonin Reuptake Inhibitors and Risk of Dental Implant Failure.
2019 Jan Clin Cardiol Low serum albumin: A significant predictor of reduced survival in patients with chronic heart failure.
2019 Jan Pathol Oncol Res MiRNA-195-5p Functions as a Tumor Suppressor and a Predictive of Poor Prognosis in Non-small Cell Lung Cancer by Directly Targeting CIAPIN1.
2019 Jan Pharmacotherapy Nonaspirin Nonsteroidal Antiinflammatory Drug Use in the Nordic Countries from a Cardiovascular Risk Perspective, 2000-2016: A Drug Utilization Study.
2019 Jan Diabetologia The effect of dapagliflozin on glycaemic control and other cardiovascular disease risk factors in type 2 diabetes mellitus: a real-world observational study.
2019 Jan Rev Med Interne [NSAID urticaria: Similar management to acute urticaria].
2019 Jan FASEB J The role of Cox-2 and prostaglandin E2 receptor EP3 in pancreatic β-cell death.
2019 Jan Ann Oncol Larotrectinib in adult patients with solid tumours: a multicentre, open-label, phase I dose-escalation study.
2018 Health Sci Rep Prognostic effect of sidedness in early stage versus advanced colon cancer.
2019 Jan Int J Mol Sci High Expression of IL-1RI and EP₂ Receptors in the IL-1βCOX-2 Pathway, and a New Alternative to Non-Steroidal Drugs-Osthole in Inhibition COX-2.
2018 Front Pharmacol Lipopolysaccharide Stimulated the Migration of NIH3T3 Cells Through a Positive Feedback Between β-Catenin and COX-2.
2018 Front Pharmacol Therapeutic Effect of the Substrate-Selective COX-2 Inhibitor IMMA in the Animal Model of Chronic Constriction Injury.
2019 Jan Am J Chin Med In Vitro and In Vivo Protective Effects of Flavonoid-Enriched Lotus Seedpod Extract on Lipopolysaccharide-Induced Hepatic Inflammation.
2019 Jan AIDS Res Hum Retroviruses Relationship between Contraindicated Drug-Drug Interactions and Subsequent Hospitalizations among Patients Living with HIV Initiating Combination Antiretroviral Therapy.
2019 Jan Clin Cancer Res Exosome-Transmitted iPSMA3i and iPSMA3-AS1i Promote Proteasome Inhibitor Resistance in Multiple Myeloma.
2019 Medicine (Baltimore) Effect of parecoxib in the treatment of postoperative cognitive dysfunction: A systematic review and meta-analysis.