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Recent literature: COX inhibitor
Date Journal Article title
2020 Mar Diabetes Obes Metab Empagliflozin reduces the risk of mortality and hospitalization for heart failure across Thrombolysis In Myocardial Infarction Risk Score for Heart Failure in Diabetes categories: Post hoc analysis of the EMPA-REG OUTCOME trial.
2020 Cancer Cell Int Identification and validation of stromal-tumor microenvironment-based types tightly associated with PD-1PD-L1 immunotherapy and outcomes in patients with gastric cancer.
2020 Mar Cells Galectin-1 Overexpression Activates the FAKPI3KAKTmTOR Pathway and Is Correlated with Upper Urinary Urothelial Carcinoma Progression and Survival.
2020 Mar Clin Res Hepatol Gastroen... Association between use of proton pump inhibitors and colorectal cancer: A nationwide population-based study.
2019 Ann Oncol Rapid, complete and sustained tumour response to the TRK inhibitor larotrectinib in an infant with recurrent, chemotherapy-refractory infantile fibrosarcoma carrying the characteristic ETV6-NTRK3 gene fusion.
2020 Mar J Recept Signal Transduct... Curcumin analogs as the inhibitors of TLR4 pathway in inflammation and their drug like potentialities: a computer-based study.
2020 Mar J Toxicol Environ Health A Parecoxib exhibits anti-inflammatory and neuroprotective effects in a rat model of transient global cerebral ischemia.
2020 Mar Clin Res Cardiol Covariate adjusted reanalysis of the I-Preserve trial.
2020 Mar J Appl Toxicol Interleukins 68 and cyclooxygenase-2 release and expressions are regulated by oxidative stress-JAK2STAT3 signaling pathway in human bronchial epithelial cells exposed to particulate matter ≤2.5 μm.
2020 Saudi J Biol Sci Diabetes as a risk factor for Alzheimer's disease in the Middle East and its shared pathological mediators.
2020 Jan Clin Lymphoma Myeloma Leuk Comparable Efficacy and Safety of Generic Imatinib and Branded Imatinib in Patients With Newly Diagnosed Chronic Myeloid Leukemia With a Consideration of Socioeconomic Characteristics: A Retrospective Study From a Single Center.
2020 Mar Urol Oncol The prognostic value of the urokinase-plasminogen activator system (uPA) in bladder cancer patients treated with radical cystectomy (RC).
2020 Theranostics Metabolic remodeling by TIGAR overexpression is a therapeutic target in esophageal squamous-cell carcinoma.
2020 Mar Biosci Rep miR-96-5p enhances cell proliferation and invasion via targeted regulation of ZDHHC5 in gastic cancer.
2020 J Enzyme Inhib Med Chem Exploring the fatty acid amide hydrolase and cyclooxygenase inhibitory properties of novel amide derivatives of ibuprofen.
2020 Mar BMJ Open Antiretroviral drug class and anaemia risk in the current treatment era among people living with HIV in the USA: a clinical cohort study.
2020 Mar Bioorg Chem New 1,2,4-triazolepyrazole hybrids linked to oxime moiety as nitric oxide donor celecoxib analogs: Synthesis, cyclooxygenase inhibition anti-inflammatory, ulcerogenicity, anti-proliferative activities, apoptosis, molecular modeling and nitric oxide release studies.
2020 Commun Biol The COX-2PGE2 pathway presses apical elimination of RasV12-transformed cells from epithelia.
2020 Brain Behav Immun Health A retrospective survival analysis of Glioblastoma patients treated with selective serotonin reuptake inhibitors.
2020 Evid Based Complement Alt... Relaxation Effect of Patchouli Alcohol in Rat Corpus Cavernous and Its Underlying Mechanisms.
2020 Mar Commun Biol The COX-2PGE2 pathway presses apical elimination of RasV12-transformed cells from epithelia.
2020 Cancer Manag Res Leucine Zipper-EF-Hand Containing Transmembrane Protein 1 Is a Potential Prognostic Biomarker and Promotes Cell Progression in Prostate Cancer.
2020 Mar J Cardiol Upper gastrointestinal bleeding in Japanese patients with ischemic heart disease receiving vonoprazan or a proton pump inhibitor with multiple antithrombotic agents: A nationwide database study.
2020 Mar Ann Coloproctol An unusual case of colon perforation with multiple transmural ulcers after use of polmacoxib and everolimus in a metastatic breast cancer patient: A case report.
2020 Mar JAMA Pediatr Association Between Proton Pump Inhibitor Use and Risk of Fracture in Children.
2020 Mar Parasite Immunol Eegulatory effect of PGE2 on microbicidal activity and inflammatory cytokines in canine leishmaniasis.
2020 Mar Eur J Pharm Sci Pharmacological appraisal of ligustrazine based cyclohexanone analogs as inhibitors of inflammatory markers.
2020 Mar Int J Biol Macromol Effect of beta- and alpha-glucans on immune modulating factors expression in enterocyte-like Caco-2 and goblet-like LS 174T cells.
2020 Profiles Drug Subst Excip... Meloxicam.
2020 Mar BMC Cancer Dissociated responses at initial computed tomography evaluation is a good prognostic factor in non-small cell lung cancer patients treated with anti-programmed cell death-1ligand 1 inhibitors.
2020 Oncologist The Impact of Nonsteroidal Anti-Inflammatory Drugs, Beta Blockers, and Metformin on the Efficacy of Anti-PD-1 Therapy in Advanced Melanoma.
2020 Front Pharmacol iShenfui Injection Promotes Vasodilation by Enhancing eNOS Activity Through the PI3KAkt Signaling Pathway iIn Vitroi.
2020 Chin Med Cryptotanshinone from iSalvia miltiorrhizai Bunge (Danshen) inhibited inflammatory responses via TLR4MyD88 signaling pathway.
2020 Front Vet Sci Upregulation of PD-L1 Expression by Prostaglandin E2 and the Enhancement of IFN-γ by Anti-PD-L1 Antibody Combined With a COX-2 Inhibitor in iMycoplasma bovisi Infection.
2020 Mar Clin Rheumatol Risk of systemic autoimmune diseases in gastric disease patients with proton pump inhibitor use: a nationwide cohort study in Taiwan.
2020 Mar J Nat Prod Citral Inhibits the Inflammatory Response and Hyperalgesia in Mice: The Role of TLR4, TLR2Dectin-1, and CB2 Cannabinoid ReceptorATP-Sensitive K+ Channel Pathways.
2020 Mar JAMA Intern Med Association Between Renin-Angiotensin System Blockade Discontinuation and All-Cause Mortality Among Persons With Low Estimated Glomerular Filtration Rate.
2020 Mar Cancer Lett Prometastatic Secretome Trafficking via Exosomes Initiates Pancreatic Cancer Pulmonary Metastasis.
2020 Mar Biosci Rep Down-regulation of protease-activated receptor 2 ameliorated osteoarthritis in rats through regulation of MAPKNF-κB signaling pathway in vivo and in vitro.
2020 Front Oncol CT-Based Radiomic Signature as a Prognostic Factor in Stage IV iALKi-Positive Non-small-cell Lung Cancer Treated With TKI Crizotinib: A Proof-of-Concept Study.
2020 Mar Arterioscler Thromb Vasc ... Activated Platelets Induce Endothelial Cell Inflammatory Response in Psoriasis Via COX-1.
2020 Mar Foods Inhibitory Effect of 1,5-Dimethyl Citrate from Sea Buckthorn (iHippophae rhamnoidesi) on Lipopolysaccharide-Induced Inflammatory Response in RAW 264.7 Mouse Macrophages.
2020 Mar Thorac Cancer Osimertinib, a third-generation EGFR tyrosine kinase inhibitor: A retrospective multicenter study of its real-world efficacy and safety in advancedrecurrent non-small cell lung carcinoma.
2020 Mar Antiinflamm Antiallergy A... Insilico and In Vitro Study: COX-2 Inhibition by Ethanol Extract of Dayak Onion Bulb (Eleutherine americana Merr) as Treatment Innovation of Benign Prostatic Hyperplasia (BPH).
2020 Mar Inflammopharmacology Pharmacological inhibition of soluble epoxide hydrolase attenuates chronic experimental autoimmune encephalomyelitis by modulating inflammatory and anti-inflammatory pathways in an inflammasome-dependent and -independent manner.
2020 Apr Bioorg Med Chem Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes.
2020 Breast Cancer Res Treat Breast cancer outcome in relation to bone mineral density and bisphosphonate use: a -study of the DATA trial.
2020 Mar J Biomol Struct Dyn Identification of new potential cyclooxygenase-2 inhibitors: insight from high throughput virtual screening of 18 million compounds combined with molecular dynamic simulation and quantum mechanics.
2020 Feb Cells Cyclooxygenases Inhibitors Efficiently Induce Cardiomyogenesis in Human Pluripotent Stem Cells.
2020 Feb Biomed Pharmacother A COX-2sEH dual inhibitor PTUPB ameliorates cecal ligation and puncture-induced sepsis in mice via anti-inflammation and anti-oxidative stress.
2020 Feb Pathol Res Pract The urokinase-type plasminogen activator and inhibitors in resectable lung adenocarcinoma.
2020 Feb Cells Hidden Cardiotoxicity of Rofecoxib Can be Revealed in Experimental Models of IschemiaReperfusion.
2020 May Nitric Oxide Decreased expression of neuronal nitric oxide synthase contributes to the endothelial dysfunction associated with cigarette smoking in human.
2020 Cancer Manag Res The Prognostic Value of Body Fat Components in Metastasis Renal Cell Carcinoma Patients Treated with TKIs.
2020 World J Oncol Sarcopenia and Visceral Adiposity Did Not Affect Efficacy of Immune-Checkpoint Inhibitor Monotherapy for Pretreated Patients With Advanced Non-Small Cell Lung Cancer.
2020 Feb JAMA Intern Med Evaluation of a Common Prescribing Cascade of Calcium Channel Blockers and Diuretics in Older Adults With Hypertension.
2020 Feb J Clin Gastroenterol Increased Acid Exposure on Pretransplant Impedance-pH Testing Is Associated With Chronic Rejection After Lung Transplantation.
2020 Bioorg Chem Development of celecoxib-derived antifungals for crop protection.
2020 May Brain Res NS398, a cyclooxygenase-2 inhibitor, reverses memory performance disrupted by imipramine in C57Bl6J mice.
2020 Feb Chirality Determination of protein binding for novel 2-(2-hydroxypropanamido)-5-trifluoromethyl benzoic acid enantiomers to rats, dogs, and humans plasma by UPLC-MSMS.
2019 Front Pharmacol Secondary Prevention Medical Therapy and Outcomes in Patients With Myocardial Infarction With Non-Obstructive Coronary Artery Disease.
2020 Feb Expert Rev Clin Pharmacol Intravenous parecoxib for early postoperative cognitive dysfunction in elderly patients: evidence from a meta-analysis.
2020 Feb Melanoma Res The prognostic role of BRAF and WNT pathways activation in kinase inhibitors-naïve clinical stage III cutaneous melanoma.
2020 Feb Curr Comput Aided Drug Des Anti-tumorigenic efficacy of Tangeretin in Liver Cancer - An in-silico approach.
2020 Feb Pharmacoepidemiol Drug Saf Effectiveness by gender and age of renin-angiotensin system blockade in heart failure-A national register-based cohort study.
2020 Feb J Neuroinflammation Dimethyl fumarate alleviates the nitroglycerin (NTG)-induced migraine in mice.
2020 Apr Biochem Biophys Res Commun The role of autonomously secreted PGE2 and its autocrineparacrine effect on bone matrix mineralization at the different stages of differentiating MC3T3-E1 cells.
2020 Feb Mol Pharm Synergistic Platinum(II) Prodrug Nanoparticles for Enhanced Breast Cancer Therapy.
2020 Neurochem Res LncRNA UCA1 Suppresses the Inflammation Via Modulating miR-203-Mediated Regulation of MEF2CNF-κB Signaling Pathway in Epilepsy.
2020 Theranostics Sex Differences Revealed in a Mouse CFA Inflammation Model with Macrophage Targeted Nanotheranostics.
2020 Lancet Oncol Fulvestrant plus capivasertib versus placebo after relapse or progression on an aromatase inhibitor in metastatic, oestrogen receptor-positive breast cancer (FAKTION): a multicentre, randomised, controlled, phase 2 trial.
2020 Feb J Cell Physiol Clinicopathological and prognostic significance of PD-1PD-L1 axis expression in patients with tongue squamous cell carcinoma.
2020 Feb Aging (Albany NY) Identification of an immune-related risk signature for predicting prognosis in clear cell renal cell carcinoma.
2020 Apr Eur J Pharmacol Gabapentin attenuates intestinal inflammation: Role of PPAR-gamma receptor.
2020 Feb Plant Dis Management of Fire Blight Using Pre-bloom Application of Prohexadione-Calcium.