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2019 Feb |
Eur J Med Chem |
Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase. |
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2019 |
PLoS One |
Ornithine decarboxylase antizyme inhibitor 2 (AZIN2) is a signature of secretory phenotype and independent predictor of adverse prognosis in colorectal cancer. |
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2019 Feb |
ACS Appl Mater Interfaces |
Facile Engineering Indomethacin Induced Paclitaxel Nanocrystal Aggregates as Carrier-Free Nanomedicine with Improved Synergetic Antitumor Activity. |
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2019 Feb |
Vet Comp Oncol |
The selective cyclooxygenase-2 inhibitor mavacoxib (Trocoxcil™) exerts anti-tumour effects in-vitro independent of cyclooxygenase-2 expression levels. |
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2018 |
Cancer Biol Med |
Prognostic factors of refractory NSCLC patients receiving anlotinib hydrochloride as the third- or further-line treatment. |
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2019 Feb |
Bioorg Chem |
Anti-inflammatory drug approach: Synthesis and biological evaluation of novel pyrazolo[3,4-d]pyrimidine compounds. |
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2019 Feb |
J Chem Inf Model |
Classification of Cyclooxygenase-2 Inhibitors using Support Vector Machine and Random Forest Methods. |
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2019 Feb |
Mol Cell Endocrinol |
Galectin-3 plays an important role in endometriosis development and is a target to endometriosis treatment. |
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2018 Nov |
Am Surg |
Serotonin-Modulating Antidepressants and Risk of Bleeding after Trauma. |
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2019 Feb |
Nutrients |
Beta-Cryptoxanthin Inhibits Lipopolysaccharide-Induced Osteoclast Differentiation and Bone Resorption via the Suppression of Inhibitor of NF-κB Kinase Activity. |
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2019 |
PLoS One |
Second-line glucose-lowering drugs added to metformin and the risk of hospitalization for heart failure: A nationwide cohort study. |
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2019 Feb |
Acta Neurol Scand |
Statins and the risk of bleeding in patients taking dabigatran. |
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2019 Feb |
J Vet Pharmacol Ther |
Pharmacokinetics of the novel COX-2 selective inhibitor vitacoxib in cats: The effects of feeding and dose. |
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2019 Feb |
Reg Anesth Pain Med |
Intravenous meloxicam for the treatment of moderate to severe acute pain: a pooled analysis of safety and opioid-reducing effects. |
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2019 Feb |
FASEB J |
Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome. |
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2019 |
Evid Based Complement Alt... |
Downregulation of Aquaporin 3 Mediated the Laxative Effect in the Rat Colon by a Purified Resin Glycoside Fraction from Pharbitis Semen. |
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2019 Feb |
Leuk Lymphoma |
Risk factors for the development of atrial fibrillation on ibrutinib treatment. |
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2019 Feb |
Life Sci |
Protective effects of febuxostat against paraquat-induced lung toxicity in rats: Impact on RAGEPI3KAkt pathway and downstream inflammatory cascades. |
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2019 Feb |
Invest New Drugs |
Clinical outcomes of advanced stage cancer patients treated with sequential immunotherapy in phase 1 clinical trials. |
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2019 Feb |
Pharmacoepidemiol Drug Saf |
Use of dipeptidyl peptidase-4 inhibitors and the risk of arthralgia: Population-based cohort and nested case-control studies. |
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2019 Feb |
J Glaucoma |
Long Term Side effects Including Blepharitis Leading to Discontinuation of Ripasudil. |
|
2019 |
Ther Adv Hematol |
A real-world comparative analysis of carfilzomib and other systemic multiple myeloma chemotherapies in a US community oncology setting. |
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2019 Feb |
Cancer Lett |
3,3'-Diindolylmethane inhibits patient-derived xenograft colon tumor growth by targeting COX12 and ERK12. |
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2019 Feb |
Rheumatology (Oxford) |
Structural efficacy of NSAIDs, COX-2 inhibitor and glucocorticoid compared with TNFα blocker: a study in adjuvant-induced arthritis rats. |
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2019 Jan |
World Neurosurg |
EGFR mutation status confers survival benefit in non-small cell lung cancer patients undergoing surgical resection of brain metastases: a retrospective cohort study. |
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2019 Jan |
Eur J Pharmacol |
Mechanisms underlying vascular hypocontractility induced by ethanol withdrawal: Role of cyclooxygenase 2-derived prostacyclin. |
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2019 Feb |
Curr Med Chem |
Current anti-inflammatory therapies and the potential of secretory Phospholipase A2 inhibitors in the design of new anti-inflammatory drugs: a review of 2012 - 2018. |
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2019 Feb |
Clin Sci (Lond) |
Activation of G protein-coupled estrogen receptor protects intestine from ischemiareperfusion injury in mice by protecting the crypt cell proliferation. |
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2019 |
Circ Cardiovasc Interv |
Association of International Normalized Ratio Stability and Bleeding Outcomes Among Atrial Fibrillation Patients Undergoing Percutaneous Coronary Intervention. |
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2019 Jan |
Pharmacology |
Impact of Different Pharmacotherapies on Long-Term Outcomes in Patients with Electrical Storm. |
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2019 Jan |
Eur J Pharmacol |
The relatively selective cyclooxygenase-2 inhibitor nimesulide: What's going on? |
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2019 |
HIV Med |
Discontinuation of dolutegravir, elvitegravircobicistat and raltegravir because of toxicity in a prospective cohort. |
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2019 Jan |
Int J Cardiol |
Heart rate reduction strategy using ivabradine in end-stage Duchenne cardiomyopathy. |
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2019 |
JBMR Plus |
Manipulation of the Alternative NF-κB Pathway in Mice Has Sexually Dimorphic Effects on Bone. |
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2018 Dec |
Clin Lung Cancer |
Clinical Relevance of EGFR- or KRAS-mutated Subclones in Patients With Advanced Non-small-cell Lung Cancer Receiving Erlotinib in a French Prospective Cohort (IFCT ERMETIC2 Cohort - Part 2). |
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2018 Dec |
Domest Anim Endocrinol |
Effects of arachidonic acid and its major prostaglandin derivatives on bovine myoblast proliferation, differentiation, and fusion. |
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2019 |
J Hypertens |
Effect of antihypertensive therapy on development of incident conduction system disease in hypertensive patients. |
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2019 |
NPJ Breast Cancer |
MONARCH 3 final PFS: a randomized study of abemaciclib as initial therapy for advanced breast cancer. |
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2019 Jan |
J Nephrol |
Cyclooxygenase 2 inhibition slows disease progression and improves the altered renal lipid mediator profile in the Pkd2WS25- mouse model of autosomal dominant polycystic kidney disease. |
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2019 Jan |
Int J Mol Sci |
HADC8 Inhibitor WK2-16 Therapeutically Targets Lipopolysaccharide-Induced Mouse Model of Neuroinflammation and Microglial Activation. |
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2019 Jan |
Aging (Albany NY) |
DNA methylation GrimAge strongly predicts lifespan and healthspan. |
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2018 Aug |
Phytomedicine |
Anti-inflammation action of xanthones from Swertia chirayita by regulating COX-2NF-κBMAPKsAkt signaling pathways in RAW 264.7 macrophage cells. |
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2018 Sep |
Phytomedicine |
The anti-inflammatory and anti-nociceptive effects of Korean black ginseng. |
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2019 Mar |
J Endocrinol |
Inhibition of TPPP3 attenuates β-cateninNF-κBCOX-2 signaling in endometrial stromal cells and impairs decidualization. |
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2019 Jan |
Cancer Immunol Immunother |
Immune checkpoint inhibitor-induced colitis as a predictor of survival in metastatic melanoma. |
|
2019 |
Mol Med Rep |
Sodium azide induces mitochondria‑mediated apoptosis in PC12 cells through Pgc‑1α‑associated signaling pathway. |
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2019 Jan |
Melanoma Res |
Overall survival after treatment for metastatic uveal melanoma: a systematic review and meta-analysis. |
|
2019 Jan |
J Labelled Comp Radiopharm |
Access to 18 F-labelled isoxazoles by ruthenium-promoted 1,3-dipolar cycloaddition of 4-[18 F]fluoro-N-hydroxybenzimidoyl chloride with alkynes. |
|
2018 |
Am J Transl Res |
Tepoxalin a dual 5-LOX-COX inhibitor and erlotinib an EGFR inhibitor halts progression of gastric cancer in tumor xenograft mice. |
|
2019 |
Prostaglandins Leukot Ess... |
Interleukin-1β and prostaglandin-synthesizing enzymes as modulators of human omental and cutaneous adipose tissue function. |
|
2019 Jan |
Clin Transl Med |
EGFR plasma mutation in prediction models for resistance with EGFR TKI and survival of non-small cell lung cancer. |
|
2019 Jan |
Int J Biol Macromol |
The anticancer properties and mechanism of action of tablysin-15, the RGD-containing disintegrin, in breast cancer cells. |
|
2019 Jan |
J Neurosurg |
Overall survival and response to radiation and targeted therapies among patients with renal cell carcinoma brain metastases. |
|
2019 Jan |
J Cell Biochem |
miR-98 acts as an inhibitor in chronic constriction injury-induced neuropathic pain via downregulation of high-mobility group AT-hook 2. |
|
2019 Jan |
Breast Cancer Res Treat |
Aromatase inhibitor and tamoxifen use and the risk of venous thromboembolism in breast cancer survivors. |
|
2019 Jan |
Rheumatology (Oxford) |
Impact of TNF inhibitor therapy on joint replacement rates in rheumatoid arthritis: a matched cohort analysis of BSRBR-RA UK registry data. |
|
2019 Jan |
Proc Natl Acad Sci U S A |
Suppression of chemotherapy-induced cytokinelipid mediator surge and ovarian cancer by a dual COX-2sEH inhibitor. |
|
2019 Jan |
J Am Heart Assoc |
ThromboticThrombolytic Balance as a Cardiac Treatment Determinant in Patients With Diabetes Mellitus and Coronary Artery Disease. |
|
2019 Jan |
Eur Radiol |
Development and validation of a prognostic index for efficacy evaluation and prognosis of first-line chemotherapy in stage III-IV lung squamous cell carcinoma. |
|
2019 Jan |
J Prosthodont |
Relationship between Selective Serotonin Reuptake Inhibitors and Risk of Dental Implant Failure. |
|
2019 Jan |
Clin Cardiol |
Low serum albumin: A significant predictor of reduced survival in patients with chronic heart failure. |
|
2019 Jan |
Pathol Oncol Res |
MiRNA-195-5p Functions as a Tumor Suppressor and a Predictive of Poor Prognosis in Non-small Cell Lung Cancer by Directly Targeting CIAPIN1. |
|
2019 Jan |
Pharmacotherapy |
Nonaspirin Nonsteroidal Antiinflammatory Drug Use in the Nordic Countries from a Cardiovascular Risk Perspective, 2000-2016: A Drug Utilization Study. |
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2019 Jan |
Diabetologia |
The effect of dapagliflozin on glycaemic control and other cardiovascular disease risk factors in type 2 diabetes mellitus: a real-world observational study. |
|
2019 Jan |
Rev Med Interne |
[NSAID urticaria: Similar management to acute urticaria]. |
|
2019 Jan |
FASEB J |
The role of Cox-2 and prostaglandin E2 receptor EP3 in pancreatic β-cell death. |
|
2019 Jan |
Ann Oncol |
Larotrectinib in adult patients with solid tumours: a multicentre, open-label, phase I dose-escalation study. |
|
2018 |
Health Sci Rep |
Prognostic effect of sidedness in early stage versus advanced colon cancer. |
|
2019 Jan |
Int J Mol Sci |
High Expression of IL-1RI and EP₂ Receptors in the IL-1βCOX-2 Pathway, and a New Alternative to Non-Steroidal Drugs-Osthole in Inhibition COX-2. |
|
2018 |
Front Pharmacol |
Lipopolysaccharide Stimulated the Migration of NIH3T3 Cells Through a Positive Feedback Between β-Catenin and COX-2. |
|
2018 |
Front Pharmacol |
Therapeutic Effect of the Substrate-Selective COX-2 Inhibitor IMMA in the Animal Model of Chronic Constriction Injury. |
|
2019 Jan |
Am J Chin Med |
In Vitro and In Vivo Protective Effects of Flavonoid-Enriched Lotus Seedpod Extract on Lipopolysaccharide-Induced Hepatic Inflammation. |
|
2019 Jan |
AIDS Res Hum Retroviruses |
Relationship between Contraindicated Drug-Drug Interactions and Subsequent Hospitalizations among Patients Living with HIV Initiating Combination Antiretroviral Therapy. |
|
2019 Jan |
Clin Cancer Res |
Exosome-Transmitted iPSMA3i and iPSMA3-AS1i Promote Proteasome Inhibitor Resistance in Multiple Myeloma. |
|
2019 |
Medicine (Baltimore) |
Effect of parecoxib in the treatment of postoperative cognitive dysfunction: A systematic review and meta-analysis. |