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Recent literature: COX inhibitor
Date Journal Article title
2019 Aug Eur J Med Chem Cyclic enaminone as new chemotype for selective cyclooxygenase-2 inhibitory, anti-inflammatory, and analgesic activities.
2019 Aug Brain Res Bull Inhibition of neuronal ferroptosis in the acute phase of intracerebral hemorrhage shows long-term cerebroprotective effects.
2019 Aug Int J Cardiol Circulating Serpina3 levels predict the major adverse cardiac events in patients with myocardial infarction.
2019 Aug Microcirculation Tetraethylammonium, glibenclamide, and 4-aminopyridine modulate post-occlusive reactive hyperaemia in non-glabrous human skin with no roles of NOS and COX.
2019 Front Genet Impact of a Complement Factor H Gene Variant on Renal Dysfunction, Cardiovascular Events, and Response to ACE Inhibitor Therapy in Type 2 Diabetes.
2019 Aug Infect Immun Functional characterization of an IFN-γ-like receptor on iEntamoeba histolyticai.
2019 Oncol Lett Significance of cyclooxygenase-2, prostaglandin E2 and CD133 levels in sunitinib-resistant renal cell carcinoma.
2019 Aug Biochem Biophys Res Commun Trans-cinnamaldehyde shows anti-depression effect in the forced swimming test and possible involvement of the endocannabinoid system.
2019 Aug Eur J Pharmacol Loss of hypothermic and anti-pyretic action of paracetamol in cyclooxygenase-1 knockout mice is indicative of inhibition of cyclooxygenase-1 variant enzymes.
2019 Aug Basic Clin Pharmacol Toxicol Aspirin for the prevention and treatment of preeclampsia: a matter of COX-1 andor COX-2 inhibition?
2019 Jun Kidney Int Acute declines in estimated glomerular filtration rate on enalapril and mortality and cardiovascular outcomes in patients with heart failure with reduced ejection fraction.
2019 Front Neurol COX-2 Inhibition by Diclofenac Is Associated With Decreased Apoptosis and Lesion Area After Experimental Focal Penetrating Traumatic Brain Injury in Rats.
2019 Oncoimmunology Characterization of the tumor immune micromilieu and its interference with outcome after concurrent chemoradiation in patients with oropharyngeal carcinomas.
2019 Aug Cancer Late mortality after bone marrow transplant for chronic myelogenous leukemia in the context of prior tyrosine kinase inhibitor exposure: A Blood or Marrow Transplant Survivor Study (BMTSS) report.
2019 Mar Eur Urol Oncol Circulating Tumor DNA Alterations in Advanced Urothelial Carcinoma and Association with Clinical Outcomes: A Pilot Study.
2019 Aug J Orthop Res Inhibition of COX-2 pathway as a potential prophylaxis against arthrofibrogenesis in a rabbit model of joint contracture.
2019 Aug Rheumatology (Oxford) Experience with tofacitinib in Canada: patient characteristics and treatment patterns in rheumatoid arthritis over 3 years.
2019 Aug Leuk Lymphoma Treatment patterns and deep molecular response in chronic phase - chronic myeloid leukemia patients treated with second-line nilotinib or dasatinib: a multi-country retrospective chart review study.
2019 Aug Toxicol Sci Polyethlyene Glycol 200 can Protect Rats against Drug-Induced Kidney Toxicity through Inhibition of the Renal Organic Anion Transporter 3.
2019 Aug Int J Mol Sci The Cyclooxigenase-2 Inhibitor Parecoxib Prevents Epidermal Dysplasia in HPV16-Transgenic Mice: Efficacy and Safety Observations.
2019 Jul Cancer Biomark Downregulation miR-539 is associated with poor prognosis of gastric cancer patients and aggressive progression of gastric cancer cells.
2019 Aug Clin Rheumatol Outcomes of dose reduction, withdrawal, and restart of tofacitinib in patients with rheumatoid arthritis: a prospective observational study.
2019 Aug Oncogene AKT-mediated phosphorylation enhances protein stability and transcription activity of ZNF322A to promote lung cancer progression.
2019 Jul - Transplant Proc Induction Type and Outcomes in HLA-DR Mismatch Kidney Transplantation.
2019 Front Pharmacol (Pro)renin Receptor-Dependent Induction of Profibrotic Factors Is Mediated by COX-2EP4NOX-4Smad Pathway in Collecting Duct Cells.
2019 Aug Neth Heart J Myocardial infarction patients referred to the primary care physician after 1‑year treatment according to a guideline-based protocol have a good prognosis.
2019 Apr Arthritis Rheumatol Risk Factors for Major Adverse Cardiovascular Events in Phase III and Long-Term Extension Studies of Tofacitinib in Patients With Rheumatoid Arthritis.
2019 Aug Int Urol Nephrol Outcomes of sirolimus regimens in 65-year-old and older kidney transplant recipients: a registry-based observational study.
2019 Mol Clin Oncol Association between EGFR exon 19 or exon 21 mutations and survival rates after first-line EGFR-TKI treatment in patients with non-small cell lung cancer.
2019 Aug J Transl Med Mesenchymal stem cells promote type 2 macrophage polarization to ameliorate the myocardial injury caused by diabetic cardiomyopathy.
2019 Aug Molecules MMI-0100 Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice through Targeting MK2 Pathway.
2019 Aug J Clin Med Efficacy and Safety of Belatacept Treatment in Renal Allograft Recipients at High Cardiovascular Risk-A Single Center Experience.
2019 Aug Semin Thromb Hemost Involvement of Platelets in Cancers.
2019 Front Pharmacol Ginkgolic Acid is a Multi-Target Inhibitor of Key Enzymes in Pro-Inflammatory Lipid Mediator Biosynthesis.
2019 Front Cell Neurosci Amelioration of Mouse Retinal Degeneration After Blue LED Exposure by Glycyrrhizic Acid-Mediated Inhibition of Inflammation.
2019 Aug Hypertension Regulation of YAP by Mammalian Target of Rapamycin Complex 1 in Endothelial Cells Controls Blood Pressure Through COX-2mPGES-1PGE2 Cascade.
2019 Jul Biomed Pharmacother All-trans retinoic acid and COX-2 cross-talk to regulate BMP9-induced osteogenic differentiation via Wntβ-catenin in mesenchymal stem cells.
2019 Aug Arthritis Care Res (Hoboken) Risk of serious infection among initiators of TNF inhibitors plus methotrexate versus triple therapy for rheumatoid arthritis: a cohort study.
2019 Jul Transl Oncol DIVERSet JAG Compounds Inhibit Topoisomerase II and Are Effective Against Adult and Pediatric High-Grade Gliomas.
2019 J Thorac Dis The imSHOX2i is capable of assessing the therapeutic effect and predicting the prognosis of stage IV lung cancer.
2019 Drug Des Devel Ther Durability of INI-containing regimens after switching from PI-containing regimens: a single-centre cohort of drug-experienced HIV-infected jects.
2019 Jul Chem Biol Interact The dual-active histamine H3 receptor antagonist and acetylcholine esterase inhibitor E100 ameliorates stereotyped repetitive behavior and neuroinflammation in sodium valproate induced autism in mice.
2019 Aug J Vet Pharmacol Ther Nonlinear mixed-effects pharmacokinetic modeling of the novel COX-2 selective inhibitor vitacoxib in dogs.
2019 Jul J Cancer Res Clin Oncol Change in neutrophil to lymphocyte ratio during immunotherapy treatment is a non-linear predictor of patient outcomes in advanced cancers.
2019 Sep J Immunol Prostaglandin E2-Induced Immune Exhaustion and Enhancement of Antiviral Effects by Anti-PD-L1 Antibody Combined with COX-2 Inhibitor in Bovine Leukemia Virus Infection.
2019 Jul J Lipid Res Lysophosphatidylcholine-induced mitochondrial fission contributes to collagen production in human cardiac fibroblasts.
2019 J Cancer Prev Baicalein Inhibits Dextran Sulfate Sodium-induced Mouse Colitis.
2019 Zhongguo Zhong Yao Za Zhi [Anti-inflammatory mechanism of Xixian Tongshuan Preparation based on molecular simulation methods].
2019 Chin J Cancer Res Impact of crizotinib on long-term survival of iALKi-positive advanced non-small-cell lung cancer: A Chinese multicenter cohort study.
2019 Jul J Mol Recognit Profiling the interaction of 1-phenylbenzimidazoles to cyclooxygenases.
2019 Jul Mol Cell Biochem Increased coronary arteriolar contraction to serotonin in juvenile pigs with metabolic syndrome.
2019 Jul J Cancer Res Clin Oncol Correlation between the qualification for bevacizumab use and the survival of patients with non-small cell lung cancer harboring the epidermal growth factor receptor mutation: a retrospective analysis.
2019 Sep Bioorg Med Chem COX-1COX-2 inhibition activities and molecular docking study of newly designed and synthesized pyrrolo[3,4-c]pyrrole Mannich bases.
2019 Jul Cancers (Basel) Dual Actions of Ketorolac in Metastatic Ovarian Cancer.
2019 Jul Expert Opin Pharmacother Celecoxib for the treatment of musculoskeletal arthritis.
2019 Jul Pharmaceutics Enhanced Oral Bioavailability of Celecoxib Nanocrystalline Solid Dispersion based on Wet Media Milling Technique: Formulation, Optimization and In VitroIn Vivo Evaluation.
2019 Jul Food Chem Toxicol Thyroid hormone-induced expression of inflammatory cytokines interfere with resveratrol-induced anti-proliferation of oral cancer cells.
2019 Jul Arthritis Res Ther Smoking status and cause-specific discontinuation of tumour necrosis factor inhibitors in axial spondyloarthritis.
2019 Jul Circulation Impact of ADCY9 Genotype on Response to Anacetrapib.
2019 Jul Int J Urol Higher immunoglobulin A nephropathy recurrence in related-donor kidney transplants: The Japan Academic Consortium of Kidney Transplantation study.
2019 Front Cell Neurosci Lipopolysaccharide-Induced Autophagy Mediates Retinal Pigment Epithelium Cells Survival. Modulation by the Phospholipase D Pathway.
2019 Jul Joint Bone Spine Drug maintenance of a second tumor necrosis factor alpha inhibitor in spondyloarthritis patients: a real-life multicenter study.
2019 Sep Eur J Pharmacol Morin induces endothelium-dependent relaxation by activating TRPV4 channels in rat mesenteric arteries.
2019 Jul Spine J Preoperative multimodal analgesia decreases 24-hour postoperative narcotic consumption in elective spinal fusion patients.
2019 J Cancer Surviv Risk of dementia among postmenopausal breast cancer survivors treated with aromatase inhibitors versus tamoxifen: a cohort study using primary care data from the UK.
2019 Lung Cancer Early serum tumor marker dynamics predict progression-free and overall survival in single PD-1PD-L1 inhibitor treated advanced NSCLC-A retrospective cohort study.
2019 Fitoterapia Screening cyclooxygenase-2 inhibitors from Andrographis paniculata to treat inflammation based on bio-affinity ultrafiltration coupled with UPLC-Q-TOF-MS.
2019 Can J Infect Dis Med Micr... Elevated Blood Urea Nitrogen-to-Serum Albumin Ratio as a Factor That Negatively Affects the Mortality of Patients with Hospital-Acquired Pneumonia.
2019 Jul J Infect Dis Neuraminidase Inhibitors and Hospital Length of Stay: A Meta-analysis of Individual Participant Data to Determine Treatment Effectiveness Among Patients Hospitalized With Nonfatal 2009 Pandemic Influenza A(H1N1) Virus Infection.
2019 Jul Sci Signal Application of a MYC degradation screen identifies sensitivity to CDK9 inhibitors in KRAS-mutant pancreatic cancer.
2019 Aliment Pharmacol Ther Earlier discontinuation of TNF-α inhibitor therapy in female patients with inflammatory bowel disease is related to a greater risk of side effects.
2019 Jul Cancer Sorafenib plus intensive chemotherapy improves survival in patients with newly diagnosed, FLT3-internal tandem duplication mutation-positive acute myeloid leukemia.
2019 Jul Heart Fail Rev Pharmacological preconditioning with phosphodiestrase inhibitor: an answer to stem cell survival against ischemic injury through JAKSTAT signaling.
2019 Jul Sci Rep Nicotinamide Augments the Anti-Inflammatory Properties of Resveratrol through PARP1 Activation.
2019 Jul Am J Kidney Dis Trends in Kidney Function Outcomes Following RAAS Inhibition in Patients With Heart Failure With Reduced Ejection Fraction.