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Recent literature: COX inhibitor
Date Journal Article title
2019 Orthop J Sports Med Effects of Perioperative Nonsteroidal Anti-inflammatory Drug Administration on Soft Tissue Healing: A Systematic Review of Clinical Outcomes After Sports Medicine Orthopaedic Surgery Procedures.
2019 Apr J Steroid Biochem Mol Biol IGF-1 reverses the osteogenic inhibitory effect of dexamethasone on BMP9-induced osteogenic differentiation in mouse embryonic fibroblasts via PI3KAKTCOX-2 pathway.
2019 Apr Thorac Cancer Lactate dehydrogenase and baseline markers associated with clinical outcomes of advanced esophageal squamous cell carcinoma patients treated with camrelizumab (SHR-1210), a novel anti-PD-1 antibody.
2019 Apr Cell Biochem Funct Ghrelin modulates intracellular signalling pathways that are critical for podocyte survival.
2019 Apr Clin Oral Investig Efficacy and safety of selective COX-2 inhibitors for pain management after third molar removal: a meta-analysis of randomized clinical trials.
2019 Curr Med Sci Efficacy of Long-term Selenium Supplementation in the Treatment of Chronic Keshan Disease with Congestive Heart Failure.
2019 Apr Open Biol Abnormal arachidonic acid metabolic network may reduce sperm motility via P38 MAPK.
2018 Iran J Pharm Res Novel Group of Imidazole Derivatives as Atypical Selective Cyclooxygenase-2 Inhibitors: Design, Synthesis and Biological Evaluation.
2019 Apr J Med Chem Discovery and Lead-optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase.
2019 Apr Inflammation (3R, 7R)-7-Acetoxyl-9-Oxo-de-O-Methyllasiodiplodin, a Secondary Metabolite of Penicillium Sp., Inhibits LPS-Mediated Inflammation in RAW 264.7 Macrophages through Blocking ERKMAPKs and NF-κB Signaling Pathways.
2016 Eur Stroke J Effect of single and dual renin-angiotensin blockade on stroke in patients with and without diabetes in VALIANT.
2019 Apr Hypertension High Altitude Reduces NO-Dependent Myometrial Artery Vasodilator Response During Pregnancy.
2019 Apr Drug Resist Updat YY1 regulates cancer cell immune resistance by modulating PD-L1 expression.
2019 Medicine (Baltimore) Predictive value of early molecular response for deep molecular response in chronic phase of chronic myeloid leukemia.
2019 Front Pharmacol Combined iSabali and iUrticai Extracts (WS® 1541) Exert Anti-proliferative and Anti-inflammatory Effects in a Mouse Model of Benign Prostate Hyperplasia.
2019 Apr Oncol Res Non-steroidal anti-inflammatory drugs sensitize CD44-overexpressing cancer cells to Hsp90 inhibitor through autophagy activation.
2019 J Ginseng Res Ginsenoside Rf inhibits cyclooxygenase-2 induction via peroxisome proliferator-activated receptor gamma in A549 cells.
2019 Apr J Am Coll Cardiol Effect of Angiotensin II Inhibitors on Gastrointestinal Bleeding in Patients With Left Ventricular Assist Devices.
2019 Apr Int J Mol Sci Cyclooxygenase-2 Activity Regulates Recruitment of VEGF-Secreting Ly6Chigh Monocytes in Ventilator-Induced Lung Injury.
2019 Apr Int J Dermatol Drug survival of biological therapy is showing class effect: updated results from Slovenian National Registry of psoriasis.
2019 Apr Aging Male TGF-βPI3KAKTmTORNF-kB pathway. Clinicopathological features in prostate cancer.
2019 Am J Transl Res Single nucleotide polymorphisms of let-7-related genes increase susceptibility to breast cancer.
2019 Front Immunol Anti-nociceptive and Anti-inflammatory Activities of Asparacosin A Involve Selective Cyclooxygenase 2 and Inflammatory Cytokines Inhibition: An iin-vitro, in-vivoi, and iin-silicoi Approach.
2019 Apr J Pharmacol Exp Ther AK106-001616, a potent and selective inhibitor of cytosolic phospholipase A2: in vivo efficacy for inflammation, neuropathic pain, and pulmonary fibrosis.
2019 Apr Biomol Ther (Seoul) 4'-O-β-D-Glucosyl-5-O-Methylvisamminol Attenuates Pro-Inflammatory Responses and Protects against Oxidative Damage.
2019 Braz Dent J Effects of Selective Versus Non-Selective COX-2 Inhibition on Experimental Periodontitis.
2019 Int J Oncol FABP5 regulates the proliferation of clear cell renal cell carcinoma cells via the PI3KAKT signaling pathway.
2019 Apr Diabetes Care Elevated Serum Uric Acid Is Associated With Greater Risk for Hypertension and Diabetic Kidney Diseases in Obese Adolescents With Type 2 Diabetes: An Observational Analysis From the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) Study.
2019 Apr Br J Clin Pharmacol DPP-4 inhibitors lower the risk of autoimmune disease in patients with type 2 diabetes mellitus: A nationwide population-based cohort study.
2019 Apr Curr Med Res Opin Real-world Impact of HbA1c reduction on treatment intensification and HbA1c goal attainment in Type 2 diabetes mellitus patients initiated on SGLT2 inhibitor.
2019 Apr Curr Med Res Opin Matching-adjusted indirect comparison of bosutinib, dasatinib, and nilotinib on survival and major cytogenetic response for treatment of second-line chronic phase chronic myeloid leukemia.
2019 Food Sci Biotechnol Chondroprotective effect of curcumin and lecithin complex in human chondrocytes stimulated by IL-1β via an anti-inflammatory mechanism.
2019 Apr BMC Infect Dis Retention in care and virological failure among adult HIV+ patients on second-line ART in Rwanda: a national representative study.
2019 Apr J Chem Neuroanat Improvement in neurogenesis and memory function by administration of Passiflora incarnata L. extract applied to sleep disorder in rodent models.
2019 Apr Am J Ophthalmol Remission Of Non-Infectious Anterior Scleritis: Incidence And Predictive Factors.
2019 J Chin Med Assoc Anti-inflammatory effect of aerial bulblets of Dioscorea japonica Thunb extract through inhibition of NF-κB and MAPK signalling pathway in RAW 264.7.
2019 Apr Inflamm Res Macrophage migration inhibitory factor (MIF) controls cytokine release during respiratory syncytial virus infection in macrophages.
2019 Apr Pathol Oncol Res The Investigation of Lipoxygenases as Therapeutic Targets in Malignant Pleural Mesothelioma.
2019 Mar Life Sci Chronic administration of sildenafil improves endothelial function in spontaneously hypertensive rats by decreasing COX-2 expression and oxidative stress.
2019 Apr J Nat Prod Anti-inflammatory Potential of Saponins from Aster tataricus via NF-κBMAPK Activation.
2019 Front Mol Neurosci Exogenous Ketone Supplementation Decreased the Lipopolysaccharide-Induced Increase in Absence Epileptic Activity in Wistar Albino Glaxo Rijswijk Rats.
2019 Expert Opin Drug Saf Potentially inappropriate concomitant medicine use with the selective COX-2 inhibitor celecoxib: Analysis and comparison of spontaneous adverse event reports from Australia, Canada and the USA.
2019 Mar Zhonghua Xue Ye Xue Za Zhi [Prognosis of clonal chromosomal abnormalities in Philadelphia negative metaphases cells in chronic myeloid leukemia with tyrosine kinase inhibitor therapy].
2019 Jun Eur J Med Chem New pyrazole derivatives: Synthesis, anti-inflammatory activity, cycloxygenase inhibition assay and evaluation of mPGES.
2019 Mar Med Res Rev ETS transcription factors as emerging drug targets in cancer.
2019 Target Oncol Prognostic Markers for Refined Stratification of IMDC Intermediate-Risk Metastatic Clear Cell Renal Cell Carcinoma Treated with First-Line Tyrosine Kinase Inhibitor Therapy.
2019 Mar Sci Rep Copper(II) complexes as potential anticancer and Nonsteroidal anti-inflammatory agents: In vitro and in vivo studies.
2019 Mar N Engl J Med Overall Survival with Fulvestrant plus Anastrozole in Metastatic Breast Cancer.
2019 Mar Amino Acids Plasma ADMA, urinary ADMA excretion, and late mortality in renal transplant recipients.
2019 Mar Int J Biol Macromol The polysaccharide from the roots of Actinidia eriantha activates RAW264.7 macrophages via regulating microRNA expression.
2019 Jun Toxicol Lett PERK regulates Nrf2ARE antioxidant pathway against dibutyl phthalate-induced mitochondrial damage and apoptosis dependent of reactive oxygen species in mouse spermatocyte-derived cells.
2019 Mar Fundam Clin Pharmacol Treatment with either COX-2 inhibitor or 5-LOX inhibitor causes no compensation between COX-2 pathway and 5-LOX pathway in chronic aluminum overload-induced liver injury in rats.
2019 Mar World Neurosurg Adverse Radiation Effect and Disease Control in Patients Undergoing Stereotactic Radiosurgery and Immune Checkpoint Inhibitor Therapy for Brain Metastases.
2019 May Bioorg Med Chem Structural modification of indomethacin toward selective inhibition of COX-2 with a significant increase in van der Waals contributions.
2019 Mar Breast Cancer Res Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.
2019 Mar Sci Rep Inhibition of PGE2EP4 receptor signaling enhances oxaliplatin efficacy in resistant colon cancer cells through modulation of oxidative stress.
2019 Mar J Antimicrob Chemother Role of transporters in the disposition of a novel β-lactamase inhibitor: relebactam (MK-7655).
2019 Apr J Am Heart Assoc Association of Circulating Tissue Inhibitor of Metalloproteinases-1 and Procollagen Type III Aminoterminal Peptide Levels With Incident Heart Failure and Chronic Kidney Disease.
2019 Mar J Vet Pharmacol Ther Pharmacokinetics, metabolism and excretion of celecoxib, a selective cyclooxygenase-2 inhibitor, in horses.
2019 J Alzheimers Dis Cyclooxygenase-2 is Essential for Mediating the Effects of Calcium Ions on Stimulating Phosphorylation of Tau at the Sites of Ser 396 and Ser 404.
2019 Transplant Direct The Changing Face of Liver Transplantation in the United States: The Effect of HCV Antiviral Eras on Transplantation Trends and Outcomes.
2019 Transplant Direct High Calcineurin Inhibitor Intrapatient Variability Is Associated With Renal Allograft Inflammation, Chronicity, and Graft Loss.
2019 J Cancer Res Ther Myricetin ameliorates cytokine-induced migration and invasion of cholangiocarcinoma cells via pression of STAT3 pathway.
2019 Apr Acta Biochim Biophys Sin ... Mogroside V inhibits LPS-induced COX-2 expressionROS production and overexpression of HO-1 by blocking phosphorylation of AKT1 in RAW264.7 cells.
2019 Feb Diabetes Metab J Dipeptidyl Peptidase-4 Inhibitors versus Other Antidiabetic Drugs Added to Metformin Monotherapy in Diabetic Retinopathy Progression: A Real World-Based Cohort Study.
2019 Mar Antioxidants (Basel) Liver Injury Induced by Carbon Tetrachloride in Mice Is Prevented by the Antioxidant Capacity of Anji White Tea Polyphenols.
2019 Mar Atherosclerosis Celecoxib aggravates atherogenesis and upregulates leukotrienes in ApoE-- mice and lipopolysaccharide-stimulated RAW264.7 macrophages.
2019 Pharmacology Effect of Caffeic Acid on Ischemia-Reperfusion-Induced Acute Renal Failure in Rats.
2019 Curr Med Sci Efficacy and Safety of COX-2 Inhibitor Parecoxib for Rigid Cystoscopy-related Pain Management in Male Patients: A Prospective, Randomized and Controlled Study.
2019 Mar Arthritis Res Ther Divergent roles of prostacyclin and PGE2 in human tendinopathy.
2019 Mar Breast Cancer Res PIK3CA alterations and benefit with neratinib: analysis from the randomized, double-blind, placebo-controlled, phase III ExteNET trial.
2019 Toxicol Ind Health The effect of manganese exposure on GnRH secretion via Nrf2mGluR5COX-2PGE2signaling pathway.
2019 Mar Int J Mol Sci Cyclooxygenase-2-Mediated Up-Regulation of Mitochondrial Transcription Factor A Mitigates the Radio-Sensitivity of Cancer Cells.
2019 Mar Ann Oncol Pre-operative ctDNA predicts survival in high-risk stage III cutaneous melanoma patients.
2019 Mar Antimicrob Agents Chemother Hepatotoxicity induced by IsoniazidLipopolysaccharide through ERS-, autophagy- and apoptosis pathway in zebrafish.