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Recent literature: HMG-CoA reductase inhibitor
Date Journal Article title
2019 Nov Clin Pharmacol Ther Association of statin and its lipophilicity with cardiovascular events in patients receiving chronic dialysis.
2019 Nov Sci Rep Characterizing the Role of HMG-CoA Reductase in Aryl Hydrocarbon Receptor-Mediated Liver Injury in C57BL6 Mice.
2019 Nov Cancer Sci Fluvastatin potentiates anticancer activity of vorinostat in renal cancer cells.
2019 Front Oncol Atorvastatin Exerts Antileukemia Activity via Inhibiting Mevalonate-YAP Axis in K562 and HL60 Cells.
2019 Sep J Steroid Biochem Mol Biol Side-chain oxysterols press the transcription of CTP: Phosphoethanolamine cytidylyltransferase and 3-hydroxy-3-methylglutaryl-CoA reductase by inhibiting the interaction of p300 and NF-Y, and H3K27 acetylation.
2019 Oct J Nat Prod Bipolaricins A-I, Ophiobolin-Type Tetracyclic Sesterterpenes from a Phytopathogenic iBipolarisi sp. Fungus.
2019 Sep Cancer Prev Res (Phila) Fluvastatin Inhibits HMG-CoA Reductase and Prevents Non-Small Cell Lung Carcinogenesis.
2019 Brain Behav Immun Lovastatin inhibits Toll-like receptor 4 signaling in microglia by targeting its co-receptor myeloid differentiation protein 2 and attenuates neuropathic pain.
2019 Neurohospitalist Recrudescence of Old Stroke Deficits Among Transient Neurological Attacks.
2019 ESC Heart Fail Impact of statins on cellular respiration and de-differentiation of myofibroblasts in human failing hearts.
2019 PLoS Pathog Epstein-Barr virus verts mevalonate and fatty acid pathways to promote infected B-cell proliferation and survival.
2019 Nov Am J Physiol Cell Physiol Statin administration activates system xC- in skeletal muscle: a potential mechanism explaining statin-induced muscle pain.
2019 J Renin Angiotensin Aldos... Effects of combined statin and ACE inhibitor therapy on endothelial function and blood pressure in essential hypertension - a randomised double-blind, placebo controlled crossover study.
2019 Sep Biochem J Ufd1 phosphorylation at serine 229 negatively regulates endoplasmic reticulum-associated degradation by inhibiting the interaction of Ufd1 with VCP.
2019 Aug J Am Med Dir Assoc Effects of Statins on Relative Risk of Fractures for Older Adults: An Updated Systematic Review With Meta-Analysis.
2019 Jul Z Evid Fortbild Qual Gesu... Analysis of secondary care data to evaluate the clinical relevance of the drug-drug interaction between amlodipine and simvastatin.
2019 Jul Sci Rep Identifying chemopreventive agents for obesity-associated cancers using an efficient, 3D high-throughput transformation assay.
2019 Eur J Immunol Statins can press DC-mediated Th2 responses through the repression of OX40-ligand and CCL17 expression.
2019 Handb Exp Pharmacol Chenodeoxycholic Acid: An Update on Its Therapeutic Applications.
2019 Oncogene Neratinib inhibits HippoYAP signaling, reduces mutant K-RAS expression, and kills pancreatic and blood cancer cells.
2019 Jun Molecules Optimization of Ultrasonic-Assisted Extraction of Total Phenolics from iCitrus aurantiumi L. Blossoms and Evaluation of Free Radical Scavenging, Anti-HMG-CoA Reductase Activities.
2019 Iran Biomed J In vitro Differentiation of Hair Follicle Stem Cell into Keratinocyte by Simvastatin
2019 May Aging (Albany NY) Modulation of Coenzyme Q10 content and oxidative status in human dermal fibroblasts using HMG-CoA reductase inhibitor over a broad range of concentrations. From mitohormesis to mitochondrial dysfunction and accelerated aging.
2019 Apr Int J Mol Sci Fluvastatin Sodium Ameliorates Obesity through Brown Fat Activation.
2019 Medicine (Baltimore) HMG CoA reductase expression as a prognostic factor in Korean patients with breast cancer: A retrospective study.
2019 Apr Biochem Biophys Res Commun Kruppel-like factor 2 mediated anti-proliferative and anti-metastasis effects of simvastatin in p53 mutant colon cancer.
2019 Biosci Biotechnol Biochem Search for transcription factors affecting productivity of the polyketide FR901512 in filamentous fungal sp. No. 14919 and identification of Drf1, a novel negative regulator of the biosynthetic gene cluster.
2019 Neurochem Res Moderate- and Low-Dose of Atorvastatin Alleviate Cognition Impairment Induced by High-Fat Diet via Sirt1 Activation.
2019 Apr Biochem Biophys Res Commun Biphasic influence of pravastatin on human cardiac microvascular endothelial cell functions under pathological and physiological conditions.
2019 Feb Sci Data A dynamic view of the proteomic landscape during differentiation of ReNcell VM cells, an immortalized human neural progenitor line.
2019 Feb Med Sci Monit Simvastatin Improves Cardiac Hypertrophy in Diabetic Rats by Attenuation of Oxidative Stress and Inflammation Induced by Calpain-1-Mediated Activation of Nuclear Factor-κB (NF-κB).
2019 Jan - Rev Iberoam Micol Simvastatin and other inhibitors of the enzyme 3-hydroxy-3-methylglutaryl coenzyme A reductase of Ustilago maydis (Um-Hmgr) affect the viability of the fungus, its synthesis of sterols and mating.
2019 J Thorac Cardiovasc Surg Rosuvastatin attenuates bioprosthetic heart valve calcification.
2019 Lab Invest Anti-cancer effect of doxorubicin is mediated by downregulation of HMG-Co A reductase via inhibition of EGFRSrc pathway.
2019 Feb J Biotechnol Inhibition of recombinant enzyme 3-hydroxy-3-methylglutaryl-CoA reductase from Candida glabrata by α-asarone-based synthetic compounds as antifungal agents.
2019 J Lipid Res Therapeutic FGF19 promotes HDL biogenesis and transhepatic cholesterol efflux to prevent atherosclerosis.
2019 Pharmacol Res Effects of statin exposure and lung cancer survival: A meta-analysis of observational studies.
2018 Nov J Am Heart Assoc Statins Reduce Thoracic Aortic Aneurysm Growth in Marfan Syndrome Mice via Inhibition of the Ras-Induced ERK (Extracellular Signal-Regulated Kinase) Signaling Pathway.
2018 Dec Trials Prevention of post-operative complications by using a HMG-CoA reductase inhibitor in patients undergoing one-lung ventilation for non-cardiac surgery: study protocol for a randomised controlled trial.
2019 Jan Biochem Biophys Res Commun CEBP homologous protein deficiency inhibits statin-induced myotoxicity.
2018 Nov Front Med Long-term effects of various types of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on changes in glomerular filtration rate in Korea.
2019 Jan StatPearls Simvastatin
2019 Jan StatPearls Ezetimibe
2018 Nov Sci Rep Identification of DKK-1 as a novel mediator of statin effects in human endothelial cells.
2019 J Lipid Res Cholesterol intake and statin use regulate neuronal G protein-gated inwardly rectifying potassium channels.
2018 Nov Org Lett Base-Mediated Direct Transformation of N-Propargylamines into 2,3,5-Tristituted 1 H-Pyrroles.
2018 Transplant Proc Graft Protective Effect of HMG-CoA Reductase Inhibitor Pravastatin in Murine Cardiac Allograft Transplantation.
2018 J Assoc Physicians India Rosuvastatin: Role in Secondary Prevention of Cardiovascular Disease.
2018 Oct Clin Exp Pharmacol Physiol Unfolding the pleiotropic facades of rosuvastatin in therapeutic intervention of myriads of neurodegenerative disorders.
2018 Oct J Clin Med The Effect of Statin Added to Systemic Anticancer Therapy: A Meta-Analysis of Randomized, Controlled Trials.
2018 J Neurosci Rural Pract The Effect of Statins in Epilepsy: A Systematic Review.
2018 J Cell Mol Med Cardioprotective cytokine interleukin-33 is up-regulated by statins in human cardiac tissue.
2018 Plant Methods Use of a temporary immersion bioreactor system for the sustainable production of thapsigargin in shoot cultures of iThapsia garganicai.
2019 Acta Ophthalmol Systemic use of calcium channel blockers associated with less increase in central retinal thickness after uncomplicated cataract surgery.
2018 Fitoterapia Eight new triterpenoids with inhibitory activity against HMG-CoA reductase from the medical mushroom Ganoderma leucocontextum collected in Tibetan plateau.
2018 Front Cell Neurosci Rosuvastatin Reduces Neuroinflammation in the Hemorrhagic Transformation After rt-PA Treatment in a Mouse Model of Experimental Stroke.
2018 Drug Des Devel Ther Pharmacokinetic interaction between fimasartan and atorvastatin in healthy male volunteers.
2018 Sep Biochem Biophys Res Commun Fluvastatin activates sirtuin 6 to regulate sterol regulatory element-binding proteins and AMP-activated protein kinase in HepG2 cells.
2018 Pak J Pharm Sci Enhanced production of Lovastatin by filamentous fungi through solid state fermentation.
2018 ESC Heart Fail Timing of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor initiation and allograft vasculopathy progression and outcomes in heart transplant recipients.
2018 Jun Pharm Res Local Application of Pyrophosphorylated Simvastatin Prevents Experimental Periodontitis.
2018 Jun Int J Mol Sci A Synergistic Anti-Cancer Effect of Troglitazone and Lovastatin in a Human Anaplastic Thyroid Cancer Cell Line and in a Mouse Xenograft Model.
2018 Jun Sci Transl Med Statins enhance efficacy of venetoclax in blood cancers.
2019 Vascul Pharmacol Atorvastatin enhances endothelial adherens junctions through promoting VE-PTP gene transcription and reducing VE-cadherin-Y731 phosphorylation.
2018 Naunyn Schmiedebergs Arch... Pharmacokinetics, metabolism, bioavailability, tissue distribution and excretion studies of 16α-hydroxycleroda-3, 13(14) Z -dien-15, 16-olide-a novel HMG-CoA reductase inhibitor.
2018 Cell Physiol Biochem Enhanced Liver Regeneration After Partial Hepatectomy in Sterol Regulatory Element-Binding Protein (SREBP)-1c-Null Mice is Associated with Increased Hepatocellular Cholesterol Availability.
2018 Korean J Food Sci Anim Re... iLactobacillus plantarumi DR7 Reduces Cholesterol via Phosphorylation of AMPK That Down-regulated the mRNA Expression of HMG-CoA Reductase.
2018 Biosci Biotechnol Biochem Isoxanthohumol stimulates ubiquitin-proteasome-dependent degradation of precursor forms of sterol regulatory element-binding proteins.
2018 May Lipids Health Dis Novel Phenoxazinones as potent agonist of PPAR-α: design, synthesis, molecular docking and in vivo studies.
2018 FEBS Open Bio Synergistic effects of HMG-CoA reductase inhibitor and angiotensin II receptor blocker on load-induced heart failure.
2018 Drug Des Devel Ther Pharmacokinetic interactions and tolerability of rosuvastatin and ezetimibe: an open-label, randomized, multiple-dose, crossover study in healthy male volunteers.
2018 PLoS One Medication burden attributable to chronic co-morbid conditions in the very old and vulnerable.
2018 Sep Food Chem In vitro and in silico studies of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitory activity of the cowpea Gln-Asp-Phe peptide.
2018 Jun Life Sci Long noncoding RNA lncARSR promotes hepatic cholesterol biosynthesis via modulating AktSREBP-2HMGCR pathway.
2018 Korean J Intern Med Effect of the anti-IL-17 antibody on allergic inflammation in an obesity-related asthma model.