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Recent literature: Ca++ channel blocker
Date Journal Article title
2019 Nov Peptides Cardiovascular effects of DWORF (dwarf open reading frame) peptide in normal and ischaemiareperfused isolated rat hearts.
2019 Front Plant Sci Genome-Wide Identification of Calcium-Dependent Protein Kinases in iChlamydomonas reinhardtiii and Functional Analyses in Nitrogen Deficiency-Induced Oil Accumulation.
2019 Nov Metab Brain Dis Verapamil attenuates scopolamine induced cognitive deficits by averting oxidative stress and mitochondrial injury - A potential therapeutic agent for Alzheimer's Disease.
2019 Nov EMBO Mol Med Disease modeling of a mutation in α-actinin 2 guides clinical therapy in hypertrophic cardiomyopathy.
2019 Jul Pharmacol Rep Lacidipine attenuates caffeine-induced anxiety-like symptoms in mice: Role of calcium-induced oxido-nitrosative stress.
2019 Oct Virology Porcine deltacoronavirus (PDCoV) modulates calcium influx to favor viral replication.
2019 Dec Bioorg Med Chem Lett An anthrone-based Kv7.27.3 channel blocker with improved properties for the investigation of psychiatric and neurodegenerative disorders.
2019 Oct J Cardiovasc Transl Res Curcumin Induces Endothelium-Dependent Relaxation by Activating Endothelial TRPV4 Channels.
2019 Oct Behav Brain Res Effects of dopamine and serotonin synthesis inhibitors on the ketamine-, d-amphetamine-, and cocaine-induced locomotor activity of preweanling and adolescent rats: sex differences.
2019 Oct Neuropharmacology Phoneutria toxin PnTx3-5 inhibits TRPV1 channel with antinociceptive action in an orofacial pain model.
2019 Oct Mol Plant Microbe Interact FlgII-28 is a Major Flagellin-Derived Defense Elicitor in Potato.
2019 Aug Korean Circ J Comparison of First-Line Dual Combination Treatments in Hypertension: Real-World Evidence from Multinational Heterogeneous Cohorts.
2019 Oct Epilepsy Behav Early polytherapy for benzodiazepine-refractory status epilepticus.
2019 Oct Biomed Pharmacother Tambulin from Zanthoxylum armatum acutely potentiates the glucose-induced insulin secretion via KATP-independent Ca2+-dependent amplifying pathway.
2019 Oct Life Sci NS8593 inhibits Ca2+ permeant channels reversing mouse airway smooth muscle contraction.
2019 Oct J Physiol Synaptic cleft microenvironment influences potassium permeation and synaptic transmission in hair cells surrounded by calyx afferents in the turtle.
2019 Front Pharmacol The Ionotropic P2X4 Receptor has Unique Properties in the Heart by Mediating the Negative Chronotropic Effect of ATP While Increasing the Ventricular Inotropy.
2019 Oct BMJ Open SCING-Spinal Cord Injury Neuroprotection with Glyburide: a pilot, open-label, multicentre, prospective evaluation of oral glyburide in patients with acute traumatic spinal cord injury in the USA.
2019 Oct J Neurophysiol Muscarinic acetylcholine receptor-dependent persistent activity of layer 5 intrinsic-bursting and regular-spiking neurons in primary auditory cortex.
2019 Oct Proc Natl Acad Sci U S A L-type voltage-gated Ca2+ channel CaV1.2 regulates chondrogenesis during limb development.
2019 Biol Pharm Bull Mechanism of Membrane Depolarization Involved in α1A-Adrenoceptor-Mediated Contraction in Rat Tail and Iliac Arteries.
2019 Sep Cells Zileuton, a 5-Lipoxygenase Inhibitor, Exerts Anti-Angiogenic Effect by Inducing Apoptosis of HUVEC via BK Channel Activation.
2019 Sep Plant J The nuclear transporter SAD2 plays a role in calcium- and H2 O2 -mediated cell death in Arabidopsis.
2019 Nov Eur J Pharmacol L-cysteinehydrogen sulfide pathway induces cGMP-dependent relaxation of corpus cavernosum and penile arteries from patients with erectile dysfunction and improves arterial vasodilation induced by PDE5 inhibition.
2019 Oct J Neurosci Amyloid-Beta Modulates Low-Threshold Activated Voltage-Gated L-Type Calcium Channels of Arcuate Neuropeptide Y Neurons Leading to Calcium Dysregulation and Hypothalamic Dysfunction.
2019 Nov J Biol Chem A Na+ leak channel cloned from iTrichoplax adhaerensi extends extracellular pH and Ca2+ sensing for the DEGENaC family close to the base of Metazoa.
2019 Sep Clin Exp Pharmacol Physiol Effects of nitric oxide on apoptosis and voltage-gated calcium channels in human cardiac myofibroblasts.
2019 Front Pharmacol IK1 Channel Agonist Zacopride Alleviates Cardiac Hypertrophy and Failure iviai Alterations in Calcium Dyshomeostasis and Electrical Remodeling in Rats.
2019 J Pharmacol Sci Genetic deletion of Cav3.2 T-type calcium channels abolishes H2S-dependent somatic and visceral pain signaling in C57BL6 mice.
2019 Sep mSphere Potential Role of Extracellular ATP Released by Bacteria in Bladder Infection and Contractility.
2019 Pharmacol Rep GABAA receptor, KATP channel and L-type Ca2+ channel is associated with facilitation effect of H2S on the baroreceptor reflex in spontaneous hypertensive rats.
2019 Pharmacol Rep Cryptostrobin and catechin isolated from Eugenia mattosii D. Legrand leaves induce endothelium-dependent and independent relaxation in spontaneously hypertensive rat aorta.
2019 Aug Nutrients Myocardial Dysfunction after Severe Food Restriction Is Linked to Changes in the Calcium-Handling Properties in Rats.
2019 Aug Microcirculation Tetraethylammonium, glibenclamide, and 4-aminopyridine modulate post-occlusive reactive hyperemia in non-glabrous human skin with no roles of NOS and COX.
2019 Aug Int J Mol Sci Discovery of Novel TASK-3 Channel Blockers Using a Pharmacophore-Based Virtual Screening.
2019 Aug Naunyn Schmiedebergs Arch... Neryl butyrate induces contractile effects on isolated preparations of rat aorta.
2019 Jul J Cardiothorac Vasc Anesth Radiological Incidence of Unilateral Pulmonary Edema After Minimally Invasive Cardiac Surgery.
2019 Mol Pharmacol Structural Basis for Diltiazem Block of a Voltage-Gated Ca2+ Channel.
2019 Nov Neuropharmacology Neuropeptide Y release in the rat spinal cord measured with Y1 receptor internalization is increased after nerve injury.
2019 Nov Behav Brain Res Influence of magnesium plementation and L-type calcium channel blocker on haloperidol-induced movement disturbances.
2019 Toxicol Rep Renoprotective effects of stevia (iStevia rebaudianai Bertoni), amlodipine, valsartan, and losartan in gentamycin-induced nephrotoxicity in the rat model: Biochemical, hematological and histological approaches.
2019 Arch Toxicol Arsenite and its trivalent methylated metabolites inhibit glucose-stimulated calcium influx and insulin secretion in murine pancreatic islets.
2019 Jul IEEE Trans Biomed Eng Non-contact High-frequency Ultrasound Microbeam Stimulation: A Novel Finding and Potential Causes of Cell Responses.
2019 J Comp Physiol B Ocean acidification: synergistic inhibitory effects of protons and heavy metals on 45Ca uptake by lobster branchiostegite membrane vesicles.
2019 Jul Exp Mol Med The inhibition of chloride intracellular channel 1 enhances Ca2+ and reactive oxygen species signaling in A549 human lung cancer cells.
2019 Br J Pharmacol Mibefradil, a T-type Ca2+ channel blocker also blocks Orai channels by action at the extracellular surface.
2019 Sep Am J Physiol Cell Physiol Control of lysosomal TRPML1 channel activity and exosome release by acid ceramidase in mouse podocytes.
2019 Aug Chem Res Toxicol Cycloheterophyllin Inhibits the Release of Glutamate from Nerve Terminals of the Rat Hippocampus.
2019 Nov - J Pharmacol Toxicol Methods Recording of multiple ion current components and action potentials in human induced pluripotent stem cell-derived cardiomyocytes via automated patch-clamp.
2019 Sep Eur J Pharmacol Evidence for TRPV4 channel induced skin vasodilatation through NOS, COX, and KCa channel mechanisms with no effect on sweat rate in humans.
2019 Jun Biomolecules Marjoram Relaxes Rat Thoracic Aorta Via a PI3-KeNOScGMP Pathway.
2019 Fundam Clin Pharmacol ARC 118925XX stimulates cation influx in bEND.3 endothelial cells.
2019 Sep Eur J Pharmacol Hydrogen sulfide inhibited L-type calcium channels (CaV1.2) via up-regulation of the channel sulfhydration in vascular smooth muscle cells.
2019 Aug Life Sci Activation of Cav1.2 and BKCa is involved in the downregulation of caffeine-induced contraction in mice mesenteric arteries.
2019 Eur Phys J C Part Fields Erratum to: Measurement of the iWi boson polarisation in mml:math xmlns:mml="http:www.w3.org1998MathMathML"mml:mrowmml:mitmml:mi mml:movermml:mrowmml:mitmml:mimml:mrow mml:mrowmml:mo¯mml:momml:mrow mml:mover mml:mrow mml:math events from ippi collisions at mml:math xmlns:mml="http:www.w3.org1998MathMathML" mml:mrowmml:msqrtmml:mismml:mimml:msqrt mml:mo=mml:mo mml:mn8mml:mn mml:mspace mml:mtextTeVmml:mtextmml:mrow mml:math in the lepton + jets channel with ATLAS.
2019 Naunyn Schmiedebergs Arch... Lacidipine attenuates reserpine-induced depression-like behavior and oxido-nitrosative stress in mice.
2019 Adv Exp Med Biol Excitation-Contraction Coupling in Ureteric Smooth Muscle: Mechanisms Driving Ureteric Peristalsis.
2019 Mol Pharmacol The Pore-Lipid Interface: Role of Amino-Acid Determinants of Lipophilic Access by Ivabradine to the hERG1 Pore Domain.
2019 Chemosphere The effects of diltiazem on growth, reproduction, energy reserves, and calcium-dependent physiology in Daphnia magna.
2019 Aug Eur J Pharmacol Involvement of different receptor types in prostaglandin E2-induced contraction and relaxation in the lower esophageal sphincter and esophageal body.
2019 May Int J Mol Sci Fendiline Enhances the Cytotoxic Effects of Therapeutic Agents on PDAC Cells by Inhibiting Tumor-Promoting Signaling Events: A Potential Strategy to Combat PDAC.
2019 Jul Am J Physiol Regul Integr... Separate and combined effects of KCa and KATP channel blockade with NOS inhibition on cutaneous vasodilation and sweating in older men during heat stress.
2019 Biomed Pharmacother Apigenin relaxes rat intrarenal arteries, depresses Ca2+-activated Cl- currents and augments voltage-dependent K+ currents of the arterial smooth muscle cells.
2019 May J Am Coll Cardiol Post-Operative Calcium-Channel Blocker Use After Radial Artery Grafting: Do We Now Have a Definitive Answer?
2019 Front Pharmacol Endothelial-Dependent and Independent Vascular Relaxation Effect of Tetrahydropalmatine on Rat Aorta.
2019 Jul Eur J Pharmacol Decreased vasodilatory effect of Tanshinone ⅡA Sodium Sulfonate on mesenteric artery in hypertension.
2019 Aug Am J Physiol Renal Physiol Deficiency of T-type Ca2+ channels Cav3.1 and Cav3.2 has no effect on angiotensin II-induced hypertension but differential effect on plasma aldosterone in mice.
2019 Aug Am J Physiol Endocrinol M... Hydrogen sulfide inhibits Ca2+-induced mitochondrial permeability transition pore opening in type-1 diabetes.
2019 Basic Clin Neurosci Characterization of Functional Effects of Two New Active Fractions Isolated From Scorpion Venom on Neuronal Ca2+ Spikes: A Possible Action on Ca2+-Dependent Dependent K+ Channels.
2019 Apr Int J Mol Sci Extracellular l-arginine Enhances Relaxations Induced by Opening of Calcium-Activated SKCa Channels in Porcine Retinal Arteriole.
2019 Ann Clin Transl Neurol Repurposing the KCa3.1 inhibitor senicapoc for Alzheimer's disease.
2019 Apr J Immunother Cancer STIM1 at the plasma membrane as a new target in progressive chronic lymphocytic leukemia.
2019 Apr Cells Parabolic, Flight-Induced, Acute Hypergravity and Microgravity Effects on the Beating Rate of Human Cardiomyocytes.
2019 Neurogastroenterol Motil Flavonoids in a crude extract of Catha edulis inhibit rat intestinal contraction via blocking Ca2+ channels.
2019 Pain Adenosine A3 receptor activation inhibits pronociceptive N-type Ca2+ currents and cell excitability in dorsal root ganglion neurons.