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Recent literature: Ca++ channel blocker
Date Journal Article title
2020 Mar Life Sci Prostanoids contribute to regulation of inwardly rectifying K+ channels in intrarenal arterial smooth muscle cells.
2020 Mar J Mol Cell Cardiol Abnormal Ca2+ handling contributes to the impairment of aortic smooth muscle contractility in Zucker diabetic fatty rats.
2020 Mar Cells Electrical Stimulation Induces Retinal Müller Cell Proliferation and Their Progenitor Cell Potential.
2020 Mar Biochem Biophys Res Commun Tannic acid, a vasodilator present in wines and beverages, stimulates Ca2+ influx via TRP channels in bEND.3 endothelial cells.
2020 Saudi Pharm J Evaluation of bronchodialatory and antimicrobial activities of iOtostegia fruticosa:i A multi-mechanistic approach.
2020 Mar Cell Death Dis Cx43 channels and signaling via IP3Ca2+, ATP, and ROSNO propagate radiation-induced DNA damage to non-irradiated brain microvascular endothelial cells.
2020 Mar Aging Cell Age attenuates the T-type CaV 3.2-RyR axis in vascular smooth muscle.
2020 Mar Biochem Biophys Res Commun Involvement of the γ1 unit of the large-conductance Ca2+-activated K+ channel in the proliferation of human somatostatinoma cells.
2020 Mar Biochem Biophys Res Commun L-selectin activation regulates Rho GTPase activity via Ca+2 influx in Sertoli cell line, ASC-17D cells.
2020 Front Physiol Contribution of TRPC Channels to Intracellular Ca2 + Dyshomeostasis in Smooth Muscle From mdx Mice.
2020 PLoS One Conditional KCa3.1-transgene induction in murine skin produces pruritic eczematous dermatitis with severe epidermal hyperplasia and hyperkeratosis.
2020 Mar Biomol Ther (Seoul) The Altered Signaling on EFS-Induced Colon Contractility in Diabetic Rats.
2020 Mar Cell Biol Int Penehyclidine hydrochloride protects against anoxiareoxygenation injury in cardiomyocytes through ATP-sensitive potassium channels, and the AktGSK-3β and AktmTOR signaling pathways.
2020 Feb Aging (Albany NY) Reduced Ca2+ spark activity contributes to detrusor overactivity of rats with partial bladder outlet obstruction.
2020 Feb Molecules In Silico, Ex Vivo and In Vivo Studies of Roflumilast as a Potential Antidiarrheal and Antispasmodic agent: Inhibition of the PDE-4 Enzyme and Voltage-gated Ca++ ion Channels.
2020 Feb Planta Med 11-Keto-β-Boswellic Acid Attenuates Glutamate Release and Kainic Acid-Induced Excitotoxicity in the Rat Hippocampus.
2020 Feb Molecules Endothelium-Independent Vasodilatory Effects of Isodillapiolglycol Isolated from iOstericum citriodorumi.
2020 Feb Am J Physiol Endocrinol M... Chronic stimulation induces adaptive potassium channel activity that restores calcium oscillations in pancreatic islets in vitro.
2020 Jan J Vis Exp Preparation and Utilization of Freshly Isolated Human Detrusor Smooth Muscle Cells for Characterization of 9-Phenanthrol-Sensitive Cation Currents.
2020 Feb Biol Trace Elem Res Myometrial Calcium and Potassium Channels Play a Pivotal Role in Chromium-Induced Relaxation in Rat Uterus: an In Vitro Study.
2019 Pak J Pharm Sci Ex-vivo antihypertensive and calcium channel blocking activity of Androsace foliosa n-hexane leaves fraction on isolated rabbit aorta.
2020 Feb J Clin Pharmacol Protective Association Between Calcium Channel Blocker Use and Breast Cancer Recurrence in Postsurgical Women: A Population-Based Case-Control Study in Taiwan.
2020 J Recept Signal Transduct... Curcumin diminishes cisplatin-induced apoptosis and mitochondrial oxidative stress through inhibition of TRPM2 channel signaling pathway in mouse optic nerve.
2020 Mol Pharmacol Phenytoin Reduces Activity of Cardiac Ryanodine Receptor 2; A Potential Mechanism for Its Cardioprotective Action.
2019 Front Physiol Pharmacological Preconditioning Using Diazoxide Regulates Store-Operated Ca2 + Channels in Adult Rat Cardiomyocytes.
2019 Front Pharmacol The Hyperpolarization-Activated Cyclic-Nucleotide-Gated Channel Blocker Ivabradine Does Not Prevent Arrhythmias in Catecholaminergic Polymorphic Ventricular Tachycardia.
2019 Pharmacol Rep Lacidipine attenuates caffeine-induced anxiety-like symptoms in mice: Role of calcium-induced oxido-nitrosative stress.
2019 Front Cell Neurosci Allopregnanolone Modulates GABAAR-Dependent CaMKIIδ3 and BDNF to Protect SH-SY5Y Cells Against 6-OHDA-Induced Damage.
2019 Pharmacol Rep Cryptostrobin and catechin isolated from Eugenia mattosii D. Legrand leaves induce endothelium-dependent and independent relaxation in spontaneously hypertensive rat aorta.
2019 Pharmacol Rep GABAA receptor, KATP channel and L-type Ca2+ channel is associated with facilitation effect of H2S on the baroreceptor reflex in spontaneous hypertensive rats.
2020 Biochem Pharmacol Volatile anaesthetics inhibit the thermosensitive nociceptor ion channel transient receptor potential melastatin 3 (TRPM3).
2020 J Mol Cell Cardiol Location and function of transient receptor potential canonical channel 1 in ventricular myocytes.
2020 Jan Naunyn Schmiedebergs Arch... Mechanism of contractile dysfunction induced by serotonin in coronary artery in spontaneously hypertensive rats.
2020 Jan Cells Case Report on: Very Early Afterdepolarizations in HiPSC-Cardiomyocytes-An Artifact by Big Conductance Calcium Activated Potassium Current (Ibk,Ca).
2020 Physiol Rep Calcium-sensing receptor regulates intestinal dipeptide absorption via Ca2+ signaling and IKCa activation.
2020 Jan Hypertens Res Pretreatment with cilnidipine attenuates hypoxiareoxygenation injury in HL-1 cardiomyocytes through enhanced NO production and action potential shortening.
2020 Jan Int J Mol Sci The Mitochondrial Ca2+ Overload via Voltage-Gated Ca2+ Entry Contributes to an Anti-Melanoma Effect of Diallyl Trisulfide.
2020 Jan Inflammopharmacology Vasorelaxant effect of 3,5,4'-trihydroxy-trans-stilbene (resveratrol) and its underlying mechanism.
2020 Mol Autism Biophysical classification of a iCACNA1Di de novo mutation as a high-risk mutation for a severe neurodevelopmental disorder.
2020 Pflugers Arch Characterization and functional roles of KCNQ-encoded voltage-gated potassium (Kv7) channels in human corpus cavernosum smooth muscle.
2020 Mar Am J Physiol Lung Cell Mo... Upregulation of airway smooth muscle calcium-sensing receptor by low-molecular-weight hyaluronan.
2020 Feb Am J Physiol Renal Physiol Contribution of Cav1.2 Ca2+ channels and store-operated Ca2+ entry to pig urethral smooth muscle contraction.
2020 Colloids Surf B Biointerf... How is the interaction of a chloride channel blocker with phospholipids influenced by divalent metal ions? Effect of unsaturation on the lipid side chain.
2020 Exp Neurol Zn2+ entry through the mitochondrial calcium uniporter is a critical contributor to mitochondrial dysfunction and neurodegeneration.
2020 Radiat Res KATP Channel Blocker Glibenclamide Prevents Radiation-Induced Lung Injury and Inhibits Radiation-Induced Apoptosis of Vascular Endothelial Cells by Increased Ca2+ Influx and Subsequent PKC Activation.
2019 Oxid Med Cell Longev Upregulation of Transient Receptor Potential Canonical Type 3 Channel via AT1RTGF-iβi1Smad23 Induces Atrial Fibrosis in Aging and Spontaneously Hypertensive Rats.
2019 Dec Sci Rep Dual action of amitriptyline on NMDA receptors: enhancement of Ca-dependent desensitization and trapping channel block.
2019 Dec Respir Res Exchange protein directly activated by cAMP (Epac) protects against airway inflammation and airway remodeling in asthmatic mice.
2020 J Pharmacol Sci Paracetamol inhibits Ca2+ permeant ion channels and Ca2+ sensitization resulting in relaxation of precontracted airway smooth muscle.
2020 Hypertension Gal-3 (Galectin-3) and KCa3.1 Mediate Heterogeneous Cell Coupling and Myocardial Fibrogenesis Driven by βAR (β-Adrenoceptor) Activation.
2019 Dec J Am Heart Assoc Rhythm Control Versus Rate Control in Patients With Atrial Fibrillation and Heart Failure With Preserved Ejection Fraction: Insights From Get With The Guidelines-Heart Failure.
2019 Dec Toxins (Basel) Curine Inhibits Macrophage Activation and Neutrophil Recruitment in a Mouse Model of Lipopolysaccharide-Induced Inflammation.
2019 J Card Surg Preventing spasm of the radial artery conduit during coronary artery bypass grafting: Nicardipine versus verapamil.
2019 Niger J Clin Pract Investigation the relaxant effects of proton pump ınhibitors and their relaxation mechanism on sheep sphincter of Oddi.
2020 Nat Biomed Eng Identification and local delivery of vasodilators for the reduction of ureteral contractions.
2020 Jan Eur J Pharmacol KCa and KV channels modulate the venoarteriolar reflex in non-glabrous human skin with no roles of KATP channels, NOS, and COX.
2019 Aging Dis Verapamil Ameliorates Motor Neuron Degeneration and Improves Lifespan in the SOD1G93A Mouse Model of ALS by Enhancing Autophagic Flux.
2019 Cardiol Res Pract GLP-1 Relaxes Rat Coronary Arteries by Enhancing ATP-Sensitive Potassium Channel Currents.
2020 Br J Pharmacol Ca2+ signalling in fibroblasts and the therapeutic potential of KCa3.1 channel blockers in fibrotic diseases.
2020 Jan Life Sci Chronic heart failure increases negative chronotropic effects of adenosine in canine sinoatrial cells via A1R stimulation and GIRK-mediated IKado.
2019 Arch Med Sci Modulator role of infliximab and methotrexate through the transient receptor potential melastatin 2 (TRPM2) channel in neutrophils of patients with rheumatoid arthritis: a pilot study.
2020 Hypertens Res Genetic factors associated with elevation of uric acid after treatment with thiazide-like diuretic in patients with essential hypertension.
2019 Nov Aging Male Ivabradine, the hyperpolarization-activated cyclic nucleotide-gated channel blocker, elicits relaxation of the human corpus cavernosum: a potential option for erectile dysfunction treatment.
2019 Mini Rev Med Chem 1,4-Dihydropyridine: A Dependable Heterocyclic Ring with the Promising and the Most Anticipable Therapeutic Effects.
2019 Dec Arch Biochem Biophys Aerobic exercise-induced inhibition of PKCαCaV1.2 pathway enhances the vasodilation of mesenteric arteries in hypertension.
2020 Br J Pharmacol Novel neuroactive steroid with hypnotic and T-type calcium channel blocking properties exerts effective analgesia in a rodent model of post-surgical pain.
2020 Mol Pharmacol The iIi iKsi Ion Channel Activator Mefenamic Acid Requires KCNE1 and Modulates Channel Gating in a Subunit-Dependent Manner.
2020 Peptides Cardiovascular effects of DWORF (dwarf open reading frame) peptide in normal and ischaemiareperfused isolated rat hearts.
2019 Dec ACS Chem Neurosci The Natural Flavonoid Naringenin Elicits Analgesia through Inhibition of NaV1.8 Voltage-Gated Sodium Channels.
2019 Front Plant Sci Genome-Wide Identification of Calcium-Dependent Protein Kinases in iChlamydomonas reinhardtiii and Functional Analyses in Nitrogen Deficiency-Induced Oil Accumulation.
2020 Metab Brain Dis Verapamil attenuates scopolamine induced cognitive deficits by averting oxidative stress and mitochondrial injury - A potential therapeutic agent for Alzheimer's Disease.
2019 Nov Can J Physiol Pharmacol Depolarization of pacemaker potentials by caffeic acid phenethyl ester in interstitial cells of Cajal from the murine small intestine.
2019 EMBO Mol Med Disease modeling of a mutation in α-actinin 2 guides clinical therapy in hypertrophic cardiomyopathy.
2019 Pharmacol Rep Lacidipine attenuates caffeine-induced anxiety-like symptoms in mice: Role of calcium-induced oxido-nitrosative stress.
2020 Jan Virology Porcine deltacoronavirus (PDCoV) modulates calcium influx to favor viral replication.