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Recent literature: Ca++ channel blocker
Date Journal Article title
2019 Aug Nutrients Myocardial Dysfunction after Severe Food Restriction Is Linked to Changes in the Calcium-Handling Properties in Rats.
2019 Aug Microcirculation Tetraethylammonium, glibenclamide, and 4-aminopyridine modulate post-occlusive reactive hyperaemia in non-glabrous human skin with no roles of NOS and COX.
2019 Aug Int J Mol Sci Discovery of Novel TASK-3 Channel Blockers Using a Pharmacophore-Based Virtual Screening.
2019 Aug Naunyn Schmiedebergs Arch... Neryl butyrate induces contractile effects on isolated preparations of rat aorta.
2019 Jul J Cardiothorac Vasc Anesth Radiological Incidence of Unilateral Pulmonary Edema After Minimally Invasive Cardiac Surgery.
2019 Aug Neuropharmacology Neuropeptide Y release in the rat spinal cord measured with Y1 receptor internalization is increased after nerve injury.
2019 Nov Behav Brain Res Influence of magnesium plementation and L-type calcium channel blocker on haloperidol-induced movement disturbances.
2019 Toxicol Rep Renoprotective effects of stevia (iStevia rebaudianai Bertoni), amlodipine, valsartan, and losartan in gentamycin-induced nephrotoxicity in the rat model: Biochemical, hematological and histological approaches.
2019 Jul Arch Toxicol Arsenite and its trivalent methylated metabolites inhibit glucose-stimulated calcium influx and insulin secretion in murine pancreatic islets.
2019 Jul IEEE Trans Biomed Eng Non-contact High-frequency Ultrasound Microbeam Stimulation: A Novel Finding and Potential Causes of Cell Responses.
2019 Jul J Comp Physiol B Ocean acidification: synergistic inhibitory effects of protons and heavy metals on 45Ca uptake by lobster branchiostegite membrane vesicles.
2019 Jul Exp Mol Med The inhibition of chloride intracellular channel 1 enhances Ca2+ and reactive oxygen species signaling in A549 human lung cancer cells.
2019 Jul Br J Pharmacol Mibefradil, a T-type Ca2+ channel blocker also blocks Orai channels by action at the extracellular surface.
2019 Jul Am J Physiol Cell Physiol Control of Lysosomal TRPML1 Channel Activity and Exosome Release by Acid Ceramidase in Mouse Podocytes.
2019 Aug Chem Res Toxicol Cycloheterophyllin Inhibits the Release of Glutamate from Nerve Terminals of the Rat Hippocampus.
2019 Jun J Pharmacol Toxicol Methods Recording of multiple ion current components and action potentials in human induced pluripotent stem cell-derived cardiomyocytes via automated patch-clamp.
2019 Sep Eur J Pharmacol Evidence for TRPV4 channel induced skin vasodilatation through NOS, COX, and KCa channel mechanisms with no effect on sweat rate in humans.
2019 Jun Biomolecules Marjoram Relaxes Rat Thoracic Aorta Via a PI3-KeNOScGMP Pathway.
2019 Jun Fundam Clin Pharmacol ARC 118925XX stimulates cation influx in bEND.3 endothelial cells.
2019 Sep Eur J Pharmacol Hydrogen sulfide inhibited L-type calcium channels (CaV1.2) via up-regulation of the channel sulfhydration in vascular smooth muscle cells.
2019 Eur Phys J C Part Fields Erratum to: Measurement of the iWi boson polarisation in mml:math xmlns:mml="http:www.w3.org1998MathMathML"mml:mrowmml:mitmml:mi mml:movermml:mrowmml:mitmml:mimml:mrow mml:mrowmml:mo¯mml:momml:mrow mml:mover mml:mrow mml:math events from ippi collisions at mml:math xmlns:mml="http:www.w3.org1998MathMathML" mml:mrowmml:msqrtmml:mismml:mimml:msqrt mml:mo=mml:mo mml:mn8mml:mn mml:mspace mml:mtextTeVmml:mtextmml:mrow mml:math in the lepton + jets channel with ATLAS.
2019 Jun Naunyn Schmiedebergs Arch... Lacidipine attenuates reserpine-induced depression-like behavior and oxido-nitrosative stress in mice.
2019 Adv Exp Med Biol Excitation-Contraction Coupling in Ureteric Smooth Muscle: Mechanisms Driving Ureteric Peristalsis.
2019 Mol Pharmacol The Pore-Lipid Interface: Role of Amino-Acid Determinants of Lipophilic Access by Ivabradine to the hERG1 Pore Domain.
2019 Chemosphere The effects of diltiazem on growth, reproduction, energy reserves, and calcium-dependent physiology in Daphnia magna.
2019 Jun J Int Med Res Hydrogen sulfide-mediated endothelial function and the interaction with eNOS and PDE5A activity in human internal mammary arteries.
2019 Aug Eur J Pharmacol Involvement of different receptor types in prostaglandin E2-induced contraction and relaxation in the lower esophageal sphincter and esophageal body.
2019 May Int J Mol Sci Fendiline Enhances the Cytotoxic Effects of Therapeutic Agents on PDAC Cells by Inhibiting Tumor-Promoting Signaling Events: A Potential Strategy to Combat PDAC.
2019 Jul Am J Physiol Regul Integr... Separate and combined effects of KCa and KATP channel blockade with NOS inhibition on cutaneous vasodilation and sweating in older men during heat stress.
2019 Biomed Pharmacother Apigenin relaxes rat intrarenal arteries, depresses Ca2+-activated Cl- currents and augments voltage-dependent K+ currents of the arterial smooth muscle cells.
2019 May J Am Coll Cardiol Post-Operative Calcium-Channel Blocker Use After Radial Artery Grafting: Do We Now Have a Definitive Answer?
2019 Front Pharmacol Endothelial-Dependent and Independent Vascular Relaxation Effect of Tetrahydropalmatine on Rat Aorta.
2019 Jul Eur J Pharmacol Decreased vasodilatory effect of Tanshinone ⅡA Sodium Sulfonate on mesenteric artery in hypertension.
2019 Aug Am J Physiol Renal Physiol Deficiency of T-type Ca2+ channels Cav3.1 and Cav3.2 has no effect on angiotensin II-induced hypertension but differential effect on plasma aldosterone in mice.
2019 Aug Am J Physiol Endocrinol M... Hydrogen sulfide inhibits Ca2+-induced mitochondrial permeability transition pore opening in type-1 diabetes.
2019 Basic Clin Neurosci Characterization of Functional Effects of Two New Active Fractions Isolated From Scorpion Venom on Neuronal Ca2+ Spikes: A Possible Action on Ca2+-Dependent Dependent K+ Channels.
2019 Apr Int J Mol Sci Extracellular l-arginine Enhances Relaxations Induced by Opening of Calcium-Activated SKCa Channels in Porcine Retinal Arteriole.
2019 Ann Clin Transl Neurol Repurposing the KCa3.1 inhibitor senicapoc for Alzheimer's disease.
2019 Apr J Immunother Cancer STIM1 at the plasma membrane as a new target in progressive chronic lymphocytic leukemia.
2019 Apr Cells Parabolic, Flight-Induced, Acute Hypergravity and Microgravity Effects on the Beating Rate of Human Cardiomyocytes.
2019 Neurogastroenterol Motil Flavonoids in a crude extract of Catha edulis inhibit rat intestinal contraction via blocking Ca2+ channels.
2019 Pain Adenosine A3 receptor activation inhibits pronociceptive N-type Ca2+ currents and cell excitability in dorsal root ganglion neurons.
2019 Epilepsia First-in-man study of ACT-709478, a novel selective triple T-type calcium channel blocker.
2019 Apr Cancers (Basel) TRPC3 Regulates the Proliferation and Apoptosis Resistance of Triple Negative Breast Cancer Cells through the TRPC3RASA4MAPK Pathway.
2019 Pharmacol Rep Verapamil prevents the effect of calcium-sensing receptor activation on the blood glucose and insulin levels in rats.
2019 Int Immunopharmacol The immunomodulatory effect of Poria cocos polysaccharides is mediated by the Ca2+PKCp38NF-κB signaling pathway in macrophages.
2019 Jun Life Sci Benidipine, an anti-hypertensive drug, relaxes mouse airway smooth muscle.
2019 Brain Res Bull Ca2+-PKCα-ERK12 signaling pathway is involved in the pressive effect of propofol on proliferation of neural stem cells from the neonatal rat hippocampus.
2019 Front Cell Neurosci Estradiol-Mediated Axogenesis of Hypothalamic Neurons Requires ERK12 and Ryanodine Receptors-Dependent Intracellular Ca2+ Rise in Male Rats.
2019 Apr Nat Commun Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing.
2019 JACC Clin Electrophysiol Comparison of Ajmaline and Procainamide Provocation Tests in the Diagnosis of Brugada Syndrome.
2019 Jun Biochem Biophys Res Commun CACNB2 is associated with aberrant RAS-MAPK signaling in hypertensive Dahl Salt-Sensitive rats.
2019 J Med Food Allicin Inhibits Glutamate Release from Rat Cerebral Cortex Nerve Terminals Through Suppressing Ca2+ Influx and Protein Kinase C Activity.
2019 Oxid Med Cell Longev Resveratrol Enhances Apoptotic and Oxidant Effects of Paclitaxel through TRPM2 Channel Activation in DBTRG Glioblastoma Cells.
2019 Jun Biochem Biophys Res Commun Structural basis for efonidipine block of a voltage-gated Ca2+ channel.
2019 Acta Physiol (Oxf) [Ca2+ ] changes in sympathetic varicosities and Schwann cells in rat mesenteric arteries-Relation to noradrenaline release and contraction.
2019 Apr Toxins (Basel) iD. russeliii Venom Mediates Vasodilatation of Resistance Like Arteries via Activation of Kv and KCa Channels.
2019 Mar Int J Mol Sci Nifedipine Modulates Renal Lipogenesis via the AMPK-SREBP Transcriptional Pathway.
2019 Clin Exp Pharmacol Physiol Mechanisms of U46619-induced contraction in mouse intrarenal artery.
2019 Am J Kidney Dis KDOQI US Commentary on the 2017 ACCAHA Hypertension Guideline.
2019 Mol Biol Rep Vincristine combination with Ca+2 channel blocker increase antitumor effects.
2019 Aug Food Chem Effects of exogenous Ca2+ on phenolic accumulation and physiological changes in germinated wheat (Triticum aestivum L.) under UV-B radiation.
2019 Mar Mol Psychiatry Functional coupling of Tmem74 and HCN1 channels regulates anxiety-like behavior in BLA neurons.
2019 Dig Dis Sci Functional Role of Basolateral ClC-2 Channels in the Regulation of Duodenal Anion Secretion in Mice.
2019 May Chem Biol Interact CRMP2-derived peptide ST2-104 (R9-CBD3) protects SH-SY5Y neuroblastoma cells against Aβ25-35-induced neurotoxicity by inhibiting the pCRMP2NMDAR2B signaling pathway.
2019 Mar Antioxidants (Basel) Hydroxycobalamin Reveals the Involvement of Hydrogen Sulfide in the Hypoxic Responses of Rat Carotid Body Chemoreceptor Cells.
2019 Pac Symp Biocomput Precision drug repurposing via convergent eQTL-based molecules and pathway targeting independent disease-associated polymorphisms.
2019 Biotechnol Biofuels iNi,iNi-dimethylformamide induces cellulase production in the filamentous fungus iTrichoderma reeseii.
2019 Cell Physiol Biochem Identification of Verapamil Binding Sites Within Human Kv1.5 Channel Using Mutagenesis and Docking Simulation.
2019 Feb Future Med Chem Discovery of new phthalazinones as vasodilator agents and novel pharmacological tools to study calcium channels.
2019 Front Neurosci Mechanisms Underlying Neuroprotection by the NSAID Mefenamic Acid in an Experimental Model of Stroke.
2019 Front Physiol Role of Phosphatidylinositol 3-Kinase (PI3K), Mitogen-Activated Protein Kinase (MAPK), and Protein Kinase C (PKC) in Calcium Signaling Pathways Linked to the α1-Adrenoceptor in Resistance Arteries.
2019 Clin Pharmacol Small-cell lung cancer growth inhibition: synergism between NMDA receptor blockade and chemotherapy.
2019 Patient Prefer Adherence The association of angiotensin receptor blocker-based combination therapy with persistence and adherence in newly treated, uncomplicated hypertensive patients.
2019 Cell Calcium Persistent Na+ influx drives L-type channel resting Ca2+ entry in rat melanotrophs.