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Recent literature: Carbonic anhydrase inhibitor
Date Journal Article title
2019 PLoS One Effects of insulin signaling on mouse taste cell proliferation.
2019 Oct Eur J Med Chem Direct and straightforward access to stituted alkyl selenols as novel carbonic anhydrase inhibitors.
2019 Nov J Med Chem Bioisosteric Development of Multitarget Nonsteroidal Anti-Inflammatory Drug-Carbonic Anhydrases Inhibitor Hybrids for the Management of Rheumatoid Arthritis.
2019 Oct Diagnostics (Basel) Comparison of Commercial ELISA Kits, a Prototype Multiplex Electrochemoluminescent Assay, and a Multiplex Bead-Based Immunoassay for Detecting a Urine-Based Bladder-Cancer-Associated Diagnostic Signature.
2019 Oct Anal Bioanal Chem Automated and enhanced extraction of a small molecule-drug conjugate using an enzyme-inhibitor interaction based SPME tool followed by direct analysis by ESI-MS.
2019 Oct Br J Pharmacol Carbonic Anhydrase II Does Not Regulate Nitrite Dependent Nitric Oxide Formation and Vasodilation.
2019 Oct Int Ophthalmol Real-life experience of using brinzolamidebrimonidine fixed drop combination in a tertiary glaucoma centre.
2019 Nov J Am Chem Soc Fast Microsecond Dynamics of the Protein-Water Network in the Active Site of Human Carbonic Anhydrase II Studied by Solid-State NMR Spectroscopy.
2019 Oct Oncogene TFAP2C regulates carbonic anhydrase XII in human breast cancer.
2019 Oct Int J Mol Sci Personalized Treatment Response Assessment for Rare Childhood Tumors Using Microcalorimetry-Exemplified by Use of Carbonic Anhydrase IX and Aquaporin 1 Inhibitors.
2019 Oct Exp Physiol Influence of methazolamide on the human control of breathing: A comparison to acetazolamide.
2019 Oct Acta Crystallogr D Struct... Structural comparison of protiated, HD-exchanged and deuterated human carbonic anhydrase IX.
2019 Vestn Oftalmol [Evaluation of the effect of prostaglandin analogues and a carbonic anhydrase inhibitorβ-blocker combination on the ocular blood flow in patients with primary open-angle glaucoma].
2019 Physiol Biochem Zool Blood and Gill Carbonic Anhydrase in the Context of a Chondrichthyan Model of CO2 Excretion.
2019 Sep Ophthalmic Genet Retinal dystrophy associated with a Kizuna (iKIZi) mutation and a predominantly macular phenotype.
2019 Pak J Pharm Sci Moxifloxacin-Ester derivatives: Synthesis, characterization and pharmacological evaluation.
2019 Sep Biochim Biophys Acta Mol ... PI3K inhibition highlights new molecular interactions involved in the skeletogenesis of Paracentrotus lividus embryos.
2019 Circ Heart Fail Adenosine Kinase Inhibition Augments Conducted Vasodilation and Prevents Left Ventricle Diastolic Dysfunction in Heart Failure With Preserved Ejection Fraction.
2019 Sci Adv New power of self-assembling carbonic anhydrase inhibitor: Short peptide-constructed nanofibers inspire hypoxic cancer therapy.
2019 Nov Bioorg Med Chem Synthesis and exploration of 2-morpholino-4-phenylthiazol-5-yl acrylamide derivatives for their effects against carbonic anhydrase I, II, IX and XII isoforms as a non-sulfonamide class of inhibitors.
2019 Bioorg Chem Synthesis, biological evaluation and in silico modelling studies of 1,3,5-tristituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective cancer-associated hCA IX isoenzyme inhibitors.
2019 Bioorg Chem Synthesis and comparative carbonic anhydrase inhibition of new Schiff's bases incorporating benzenesulfonamide, methanesulfonamide, and methylsulfonylbenzene scaffolds.
2019 Sep Sci Rep Engineered Carbonic Anhydrase VI-Mimic Enzyme Switched the Structure and Affinities of Inhibitors.
2019 Expert Rev Neurother Contemporary management of the pseudotumor cerebri syndrome.
2019 Nov Eur J Med Chem From random to rational: A discovery approach to selective nanomolar inhibitors of human carbonic anhydrase IV based on the Castagnoli-Cushman multicomponent reaction.
2019 Nov Eur J Med Chem Structure-activity relationship with pyrazoline-based aromatic sulfamates as carbonic anhydrase isoforms I, II, IX and XII inhibitors: Synthesis and biological evaluation.
2019 Bioorg Chem Pyrazole[3,4-d]pyridazine derivatives: Molecular docking and explore of acetylcholinesterase and carbonic anhydrase enzymes inhibitors as anticholinergics potentials.
2019 PLoS One Role of carbonic anhydrase in acute recovery following renal ischemia reperfusion injury.
2019 Jul ACS Omega Naphthalimide-Based Template for Inhibitor Screening via Cross-Linking and In-Gel Fluorescence: A Case Study against HCA II.
2019 Expert Opin Ther Pat Treatment of glaucoma and ocular hypertension using rho kinase inhibitors: patent evaluation of US2018244666 and US2018256595.
2019 Expert Opin Drug Discov Advances in the structural annotation of human carbonic anhydrases and impact on future drug discovery.
2019 Feb 5 Acute, Sustained, Intraoc...
2019 J Enzyme Inhib Med Chem Exploring benzoxaborole derivatives as carbonic anhydrase inhibitors: a structural and computational analysis reveals their conformational variability as a tool to increase enzyme selectivity.
2019 Nov Eur J Med Chem Carbonic anhydrase inhibitors based on sorafenib scaffold: Design, synthesis, crystallographic investigation and effects on primary breast cancer cells.
2019 Aug Intern Med J The Addition of Low Dose Acetazolamide as an adjunct in patients undergoing High dose Methotrexate is safe and beneficial.
2019 J Enzyme Inhib Med Chem Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold.
2019 Nov Eur J Med Chem Synthesis of novel tellurides bearing benzensulfonamide moiety as carbonic anhydrase inhibitors with antitumor activity.
2019 Aug Cancers (Basel) Type 1 Sodium Calcium Exchanger Forms a Complex with Carbonic Anhydrase IX and Via Reverse Mode Activity Contributes to pH Control in Hypoxic Tumors.
2019 Nov Anal Chim Acta Capillary isoelectric focusing with free or immobilized pH gradient in silica particles packed column.
2019 Bioorg Chem Synthesis, molecular docking analysis and carbonic anhydrase I-II inhibitory evaluation of new sulfonamide derivatives.
2019 Aug Am J Ophthalmol Factors Impacting Outcomes and the Time to Recovery From Malignant Glaucoma.
2019 Front Pharmacol Carbonic Anhydrase 1-Mediated Calcification Is Associated With Atherosclerosis, and Methazolamide Alleviates Its Pathogenesis.
2019 J Food Biochem The effects of hesperidin on sodium arsenite-induced different organ toxicity in rats on metabolic enzymes as antidiabetic and anticholinergics potentials: A biochemical approach.
2019 Sep Bioorg Med Chem Evaluation of α-hydroxycinnamic acids as pyruvate carboxylase inhibitors.
2019 Bioorg Chem Ureidobenzenesulfonamides as efficient inhibitors of carbonic anhydrase II.
2019 Jul Polymers (Basel) Amphiphilic Acrylic Nanoparticles Containing the Poloxamer Star Bayfit® 10WF15 as Ophthalmic Drug Carriers.
2019 Jul Cancers (Basel) Harnessing Induced Essentiality: Targeting Carbonic Anhydrase IX and Angiogenesis Reduces Lung Metastasis of Triple Negative Breast Cancer Xenografts.
2019 Front Pharmacol Efficacy and Safety of Brinzolamide as Add-On to Prostaglandin Analogues or β-Blocker for Glaucoma and Ocular Hypertension: A Systematic Review and Meta-Analysis.
2019 Aug J Med Chem Synthesis and Evaluation of Carbonic Anhydrase Inhibitors with Carbon Monoxide Releasing Properties for the Management of Rheumatoid Arthritis.
2019 Semin Ophthalmol A Retrospective Study of Transcleral Cyclophotocoagulation Using the Slow Coagulation Technique for the Treatment of Refractory Glaucoma.
2019 Jun Cancers (Basel) Comparative Transcriptomic Analysis of Temozolomide Resistant Primary GBM Stem-Like Cells and Recurrent GBM Identifies Up-Regulation of the Carbonic Anhydrase iCA2i Gene as Resistance Factor.
2019 Jun Mol Cells Crystal Structure of a Highly Thermostable α-Carbonic Anhydrase from Persephonella marina EX-H1.
2019 PLoS Genet Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL.
2019 Jan StatPearls Ibuprofen
2019 J Ophthalmol Timolol 0.1% in Glaucomatous Patients: Efficacy, Tolerance, and Quality of Life.
2019 May J Biomol Struct Dyn Computational modeling of novel inhibitory peptides targeting proteoglycan like region of carbonic anhydrase IX and iin vitroi validation in HeLa cells.
2019 Sep Eur J Med Chem Benzensulfonamides bearing spyrohydantoin moieties act as potent inhibitors of human carbonic anhydrases II and VII and show neuropathic pain attenuating effects.
2019 Nov - J Allergy Clin Immunol Pract Carbonic anhydrase inhibitor-induced Stevens-Johnson syndrometoxic epidermal necrolysis leads to extensive cutaneous involvement.
2019 Arch Pharm (Weinheim) Synthesis, characterization, molecular docking and biological activities of novel pyrazoline derivatives.
2019 Pflugers Arch Ciliary beating amplitude controlled by intracellular Cl- and a high rate of CO2 production in ciliated human nasal epithelial cells.
2019 May Vet Ophthalmol The effects of topical dorzolamide 2% and brinzolamide 1%, either alone or combined with timolol 0.5%, on intraocular pressure, pupil diameter, and heart rate in healthy cats.
2019 May Chem Commun (Camb) Polypharmacology of epacadostat: a potent and selective inhibitor of the tumor associated carbonic anhydrases IX and XII.
2019 Apr Crit Care Trial sequential analysis suggested the potential overestimated effect of carbonic anhydrase inhibitor for respiratory failure and metabolic alkalosis.
2019 Ophthalmol Retina Macular Hole Closure with Topical Carbonic Anhydrase Inhibitor.
2019 Comput Biol Chem A selectivity study of benzenesulfonamide derivatives on human carbonic anhydrase IIIX by 3D-QSAR, Molecular Docking and Molecular Dynamics Simulation.
2019 Apr Int J Mol Sci Pain Relieving Effect of-NSAIDs-CAIs Hybrid Molecules: Systemic and Intra-Articular Treatments against Rheumatoid Arthritis.
2019 Front Neurol Brain Edema Formation and Functional Outcome After Surgical Decompression in Murine Closed Head Injury Are Modulated by Acetazolamide Administration.
2019 Apr ACS Nano Quercetin-Modified Metal-Organic Frameworks for Dual Sensitization of Radiotherapy in Tumor Tissues by Inhibiting the Carbonic Anhydrase IX.
2019 Methods Mol Biol Thermodynamic and Kinetic Analysis of Isothermal Titration Calorimetry Experiments by Using KinITC in AFFINImeter.
2019 Apr J Med Chem Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma.
2019 Bioorg Chem Design, synthesis, and carbonic anhydrase inhibition activity of benzenesulfonamide-linked novel pyrazoline derivatives.
2019 Apr Carbohydr Res Synthesis of saccharin-glycoconjugates targeting carbonic anhydrase using a one-pot cyclizationdeprotection strategy.
2019 AoB Plants Photosynthetic acclimation of terrestrial and merged leaves in the amphibious plant iHygrophila difformisi.
2019 Am J Ophthalmol Effect of Topical Hypotensive Medications for Preventing Intraocular Pressure Increase after Cataract Surgery in Eyes with Glaucoma.
2019 Biochimie Highly active extracellular α-class carbonic anhydrase of Cyanothece sp. ATCC 51142.