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Recent literature: Carbonic anhydrase inhibitor
Date Journal Article title
2019 Jun PLoS Genet Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL.
2019 Jan StatPearls Ibuprofen
2019 J Ophthalmol Timolol 0.1% in Glaucomatous Patients: Efficacy, Tolerance, and Quality of Life.
2019 May J Biomol Struct Dyn Computational modeling of novel inhibitory peptides targeting proteoglycan like region of carbonic anhydrase IX and iin vitroi validation in HeLa cells.
2019 Sep Eur J Med Chem Benzensulfonamides bearing spyrohydantoin moieties act as potent inhibitors of human carbonic anhydrases II and VII and show neuropathic pain attenuating effects.
2019 May J Allergy Clin Immunol Pract Carbonic anhydrase inhibitor-induced Stevens-Johnson syndrometoxic epidermal necrolysis leads to extensive cutaneous involvement.
2019 Arch Pharm (Weinheim) Synthesis, characterization, molecular docking and biological activities of novel pyrazoline derivatives.
2019 May Pflugers Arch Ciliary beating amplitude controlled by intracellular Cl- and a high rate of CO2 production in ciliated human nasal epithelial cells.
2019 May Vet Ophthalmol The effects of topical dorzolamide 2% and brinzolamide 1%, either alone or combined with timolol 0.5%, on intraocular pressure, pupil diameter, and heart rate in healthy cats.
2019 May Chem Commun (Camb) Polypharmacology of epacadostat: a potent and selective inhibitor of the tumor associated carbonic anhydrases IX and XII.
2019 Apr Crit Care Trial sequential analysis suggested the potential overestimated effect of carbonic anhydrase inhibitor for respiratory failure and metabolic alkalosis.
2019 Ophthalmol Retina Macular Hole Closure with Topical Carbonic Anhydrase Inhibitor.
2019 Comput Biol Chem A selectivity study of benzenesulfonamide derivatives on human carbonic anhydrase IIIX by 3D-QSAR, Molecular Docking and Molecular Dynamics Simulation.
2019 Apr Int J Mol Sci Pain Relieving Effect of-NSAIDs-CAIs Hybrid Molecules: Systemic and Intra-Articular Treatments against Rheumatoid Arthritis.
2019 Front Neurol Brain Edema Formation and Functional Outcome After Surgical Decompression in Murine Closed Head Injury Are Modulated by Acetazolamide Administration.
2019 Apr ACS Nano Quercetin-Modified Metal-Organic Frameworks for Dual Sensitization of Radiotherapy in Tumor Tissues by Inhibiting the Carbonic Anhydrase IX.
2019 Methods Mol Biol Thermodynamic and Kinetic Analysis of Isothermal Titration Calorimetry Experiments by Using KinITC in AFFINImeter.
2019 Apr J Med Chem Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma.
2019 Bioorg Chem Design, synthesis, and carbonic anhydrase inhibition activity of benzenesulfonamide-linked novel pyrazoline derivatives.
2019 Apr Carbohydr Res Synthesis of saccharin-glycoconjugates targeting carbonic anhydrase using a one-pot cyclizationdeprotection strategy.
2019 AoB Plants Photosynthetic acclimation of terrestrial and merged leaves in the amphibious plant iHygrophila difformisi.
2019 Mar Am J Ophthalmol Effect of Topical Hypotensive Medications for Preventing Intraocular Pressure Increase after Cataract Surgery in Eyes with Glaucoma.
2019 Biochimie Highly active extracellular α-class carbonic anhydrase of Cyanothece sp. ATCC 51142.
2019 Apr Mol Pharm Development of the 99mTc-Hydroxamamide Complex as a Probe Targeting Carbonic Anhydrase IX.
2019 Bioorg Chem Synthesis of benzensulfonamides linked to quinazoline scaffolds as novel carbonic anhydrase inhibitors.
2019 Mar Int J Mol Sci Novel 8-Substituted Coumarins That Selectively Inhibit Human Carbonic Anhydrase IX and XII.
2019 Mar Acta Crystallogr F Struct... Carbonic anhydrase II in complex with carboxylic acid-based inhibitors.
2019 J Enzyme Inhib Med Chem Evaluation of the anticancer potential of a sulphonamide carbonic anhydrase IX inhibitor on cervical cancer cells.
2019 Feb Mini Rev Med Chem Pharmacophores modeling in terms of prediction of theoretical physico-chemical properties and verification by experimental correlations of Carbacylamidophosphates (CAPh) and Sulfanylamidophosphates (SAPh) Tested as New Carbonic Anhydrase Inhibitors.
2019 Mar Life Sci Glaucoma: Current treatment and impact of advanced drug delivery systems.
2019 PLoS One Oculohypotensive effects of various acetozolamide nanopreparations for topical treatment of animal model-induced glaucoma and their impact on optic nerve.
2019 eNeuro Modes of Accessing Bicarbonate for the Regulation of Membrane Guanylate Cyclase (ROS-GC) in Retinal Rods and Cones.
2018 Afr Health Sci Inhibition of cell proliferation, migration and colony formation of LS174T Cells by carbonic anhydrase inhibitor.
2019 Bioorg Chem Design, synthesis and biological evaluation of coumarin-3-carboxamides as selective carbonic anhydrase IX and XII inhibitors.
2019 J Bioenerg Biomembr Carbonic anhydrase-IX inhibition enhances the efficacy of hexokinase II inhibitor for hepatocellular carcinoma in a murine model.
2019 Bioorg Chem Discovery of new organoselenium compounds as antileishmanial agents.
2019 Oncol Rep Cellular and radiobiological effects of carbonic anhydrase IX in human breast cancer cells.
2019 Bioorg Chem Benzenesulfonamides incorporating nitrogenous bases show effective inhibition of β-carbonic anhydrases from the pathogenic fungi Cryptococcus neoformans, Candida glabrata and Malassezia globosa.
2019 Feb J Struct Biol Using neutron crystallography to elucidate the basis of selective inhibition of carbonic anhydrase by saccharin and a derivative.
2019 Bioorg Chem Synthesis and biological evaluation of novel tris-chalcones as potent carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and α-glycosidase inhibitors.
2019 Jan Fluids Barriers CNS Disruption of the hippocampal and hypothalamic blood-brain barrier in a diet-induced obese model of type II diabetes: prevention and treatment by the mitochondrial carbonic anhydrase inhibitor, topiramate.
2019 Arch Pharm (Weinheim) Microwave-assisted synthesis of 1-stituted-1H-benzimidazolium salts: Non-competitive inhibition of human carbonic anhydrase I and II.
2019 Aging Cell Sirt1-hypoxia-inducible factor-1α interaction is a key mediator of tubulointerstitial damage in the aged kidney.
2019 Bioorg Chem Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity.
2019 FASEB J Genetic mutation of Kcnj16 identifies Kir5.1-containing channels as key regulators of acute and chronic pH homeostasis.
2019 Arch Pharm (Weinheim) Aminopyrazole-stituted metallophthalocyanines: Preparation, aggregation behavior, and investigation of metabolic enzymes inhibition properties.
2019 J Biochem Mol Toxicol Evaluation of antimicrobial, antibiofilm and carbonic anhydrase inhibition profiles of 1,3-bis-chalcone derivatives.
2019 Expert Opin Ther Pat Targeted treatment of anaerobic cancer. Patent evaluation of US2016279084 and US2017056350.
2018 Dec Invest Ophthalmol Vis Sci Prospective Evaluation of Patients With X-Linked Retinoschisis During 18 Months.
2019 J Fr Ophtalmol [Selective laser trabeculoplasty in African blacks].
2018 Dec Int J Mol Sci Sulfonamide Inhibition Studies of a New β-Carbonic Anhydrase from the Pathogenic Protozoan iEntamoeba histolyticai.
2019 J Plant Physiol The presence of the low molecular mass carbonic anhydrase in photosystem II of C3 higher plants.
2019 J Biochem Mol Toxicol Synthesis and characterization of novel stituted thiophene derivatives and discovery of their carbonic anhydrase and acetylcholinesterase inhibition effects.
2018 Nov Molecules Cloning, Characterization and Anion Inhibition Studies of a β-Carbonic Anhydrase from the Pathogenic Protozoan iEntamoeba histolyticai.
2019 Feb Am J Physiol Renal Physiol Furosemide reduces BK-αβ4-mediated K+ secretion in mice on an alkaline high-K+ diet.
2019 Bioorg Chem SLC-0111 enaminone analogs, 34-(3-aryl-3-oxopropenyl) aminobenzenesulfonamides, as novel selective nanomolar inhibitors of the tumor-associated carbonic anhydrase isoform IX.
2018 PLoS One Selective inhibition of carbonic anhydrase IX over carbonic anhydrase XII in breast cancer cells using benzene sulfonamides: Disconnect between activity and growth inhibition.
2019 Bioorg Chem Synthesis, characterization, crystal structure of novel bis-thiomethylcyclohexanone derivatives and their inhibitory properties against some metabolic enzymes.
2018 Expert Opin Investig Drugs Carbonic anhydrase inhibitors as emerging agents for the treatment and imaging of hypoxic tumors.
2019 Bioorg Chem Synthesis and carbonic anhydrase inhibitory properties of novel 4-(2-aminoethyl)benzenesulfonamide-dipeptide conjugates.
2018 Nov Molecules Carbonic Anhydrase Inhibitors as Novel Drugs against Mycobacterial β-Carbonic Anhydrases: An Update on iIn Vitroi and iIn Vivoi Studies.
2019 Jan Chemistry Phosphorus versus Sulfur: Discovery of Benzenephosphonamidates as Versatile Sulfonamide-Mimic Chemotypes Acting as Carbonic Anhydrase Inhibitors.
2018 Oxf Med Case Reports Acetazolamide promotes decreased consumption of carbonated drinks and weight loss.
2019 New Phytol A thylakoid-located carbonic anhydrase regulates CO2 uptake in the cyanobacterium Synechocystis sp. PCC 6803.
2019 Bioorg Chem Synthesis of 1,2,4-triazole-5-on derivatives and determination of carbonic anhydrase II isoenzyme inhibition effects.
1993 GeneReviews<sup>®&l... Episodic Ataxia Type 1
2018 Oct Crit Care Carbonic anhydrase inhibitors in patients with respiratory failure and metabolic alkalosis: a systematic review and meta-analysis of randomized controlled trials.
2018 Front Oncol Derivation of Breast Cancer Cell Lines Under Physiological (5%) Oxygen Concentrations.
2019 J Enzyme Inhib Med Chem The carbonic anhydrase IX inhibitor SLC-0111 sensitises cancer cells to conventional chemotherapy.
2018 Onco Targets Ther Carbonic anhydrase IX enhances tumor cell proliferation and tumor progression in osteosarcoma.
2018 Oct ACS Med Chem Lett Famotidine, an Antiulcer Agent, Strongly Inhibits iHelicobacter pylorii and Human Carbonic Anhydrases.
2018 Front Genet Gene Co-expression Analysis Indicates Potential Pathways and Regulators of Beef Tenderness in Nellore Cattle.
2019 Bioorg Chem Synthesis, characterization, crystal structure of the coordination polymer Zn(II) with thiosemicarbazone of glyoxalic acid and their inhibitory properties against some metabolic enzymes.
2019 Jan StatPearls Acetazolamide
2019 Med Chem Carbonic Anhydrase Inhibitory Potential of 1,2,4-triazole-3-thione Derivatives of Flurbiprofen, Ibuprofen and 4-tert-butylbenzoic Hydrazide: Design, Synthesis, Characterization, Biochemical Evaluation, Molecular Docking and Dynamic Simulation Studies.