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Recent literature: Carbonic anhydrase inhibitor
Date Journal Article title
2020 Mar Expert Opin Drug Discov Exploring the multiple binding modes of inhibitors to carbonic anhydrases for novel drug discovery.
2020 Mar Eur J Med Chem Tail approach synthesis of novel benzenesulfonamides incorporating 1,3,4-oxadiazole hybrids as potent inhibitor of carbonic anhydrase I, II, IX, and XII isoenzymes.
2020 J Enzyme Inhib Med Chem S-stituted 2-mercaptoquinazolin-4(3H)-one and 4-ethylbenzensulfonamides act as potent and selective human carbonic anhydrase IX and XII inhibitors.
2020 Mar Bioorg Chem Appliance of the piperidinyl-hydrazidoureido linker to benzenesulfonamide compounds: Synthesis, in vitro and in silico evaluation of potent carbonic anhydrase II, IX and XII inhibitors.
2020 Mar Expert Opin Drug Metab To... An update on drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors.
2020 Mar Int J Mol Sci Sulfonamide Inhibition Studies of an α-Carbonic Anhydrase from iSchistosoma mansonii, a Platyhelminth Parasite Responsible for Schistosomiasis.
2020 Mar ChemMedChem 5-[2-(N-(Substituted phenyl)acetamide)]amino-1,3,4-thiadiazole-2-sulfonamides as Selective Carbonic Anhydrase II Inhibitors with Neuroprotective Effects.
2020 J Enzyme Inhib Med Chem Combining carbonic anhydrase and thioredoxin reductase inhibitory motifs within a single molecule dramatically increases its cytotoxicity.
2020 Mar J Biomol Struct Dyn Calcium channel blockers: molecular docking and inhibition studies on carbonic anhydrase I and II isoenzymes.
2020 Bioorg Chem X-ray crystallography of Epacadostat in adduct with Carbonic Anhydrase IX.
2020 J Enzyme Inhib Med Chem 7-Acylamino-3H-1,2-benzoxathiepine 2,2-dioxides as new isoform-selective carbonic anhydrase IX and XII inhibitors.
2020 Feb J Appl Physiol (1985) Effect of acetazolamide on susceptibility to central sleep apnea in chronic spinal cord injury.
2020 Mar Eur J Med Chem Inclusion of a 5-fluorouracil moiety in nitrogenous bases derivatives as human carbonic anhydrase IX and XII inhibitors produced a targeted action against MDA-MB-231 and T47D breast cancer cells.
2020 Feb J Am Chem Soc Sanger's Reagent Sensitized Photocleavage of Amide Bond for Constructing Photocages and Regulation of Biological Functions.
2020 Feb Eur J Ophthalmol Resolution of optic disc pit-associated macular retinoschisis after topical carbonic anhydrase inhibitor treatment: Report of a case.
2019 Vestn Oftalmol [The effect of preservative-free treatment of primary open-angle glaucoma on the state of ocular surface in combination therapy (intermediate results)].
2020 Jan Virchows Arch ALK-rearranged renal cell carcinoma with a novel PLEKHA7-ALK translocation and metanephric adenoma-like morphology.
2020 Mar Eur J Med Chem Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation.
2020 J Enzyme Inhib Med Chem A class of carbonic anhydrase IXXII - selective carboxylate inhibitors.
2020 Jan Int J Mol Sci Evaluation of Thio- and Seleno-Acetamides Bearing Benzenesulfonamide as Inhibitor of Carbonic Anhydrases from Different Pathogenic Bacteria.
2020 Jan Metabolites Sulfonamide Inhibition Profile of the β-Carbonic Anhydrase from iMalassezia restrictai, An Opportunistic Pathogen Triggering Scalp Conditions.
2020 Mar Biochem Biophys Res Commun Parathyroid hormone increases CFTR expression and function in Caco-2 intestinal epithelial cells.
2020 J Enzyme Inhib Med Chem Coumarins from iMagydaris pastinaceai as inhibitors of the tumour-associated carbonic anhydrases IX and XII: isolation, biological studies and in silico evaluation.
2020 Jan Cancers (Basel) Inhibition of PP2A with LB-100 Enhances Efficacy of CAR-T Cell Therapy Against Glioblastoma.
2020 Arch Pharm (Weinheim) Synthesis and characterization of some new pyrazolines and their inhibitory potencies against carbonic anhydrases.
2020 Bioorg Chem Benzimidazole derivatives as potent and isoform selective tumor-associated carbonic anhydrase IXXII inhibitors.
2020 J Enzyme Inhib Med Chem Synthesis and human carbonic anhydrase I, II, VA, and XII inhibition with novel amino acid-sulphonamide conjugates.
2020 Feb Eur J Med Chem Pyrrolo and pyrrolopyrimidine sulfonamides act as cytotoxic agents in hypoxia via inhibition of transmembrane carbonic anhydrases.
2019 Dec J Microbiol Biotechnol Two flavonoid-based compounds from iMurraya paniculatai as novel human carbonic anhydrase isozyme II inhibitors detected by a resazurin yeast-based assay.
2019 Dec J Ocul Pharmacol Ther Dexamethasone Implant Produces Better Outcomes than Oral Acetazolamide in Patients with Cystoid Macular Edema Secondary to Retinitis Pigmentosa.
2020 J Enzyme Inhib Med Chem A potentiated cooperation of carbonic anhydrase IX and histone deacetylase inhibitors against cancer.
2020 J Enzyme Inhib Med Chem Development of a cheminformatics platform for selectivity analyses of carbonic anhydrase inhibitors.
2020 Jan Proc Natl Acad Sci U S A High-density chemical cross-linking for modeling protein interactions.
2020 Int Urol Nephrol Adjunctive acetazolamide therapy for the treatment of Bartter syndrome.
2020 J Sleep Res Carbonic anhydrase, obstructive sleep apnea and hypertension: Effects of intervention.
2020 Jan Dalton Trans Design, synthesis, characterization of peripherally tetra-pyridine-triazole-stituted phthalocyanines and their inhibitory effects on cholinesterases (AChEBChE) and carbonic anhydrases (hCA I, II and IX).
2019 J Pain Res Remifentanil-Induced Secondary Hyperalgesia Is Not Prevented By Preoperative Acetazolamide Administration In Patients Undergoing Total Thyroidectomy: A Randomized Controlled Trial.
2019 Dec Ophthalmologica Dilatation of Retinal Arterioles Induced by Topical Dorzolamide for One Week Is Impaired in Patients with Type 1 Diabetes and Mild Retinopathy.
2020 J Enzyme Inhib Med Chem Aryl derivatives of 3H-1,2-benzoxathiepine 2,2-dioxide as carbonic anhydrase inhibitors.
2020 J Enzyme Inhib Med Chem Benzothiazole derivatives as anticancer agents.
2020 Jan Eur J Med Chem Sulfonamidesulfamate switch with a series of piperazinylureido derivatives: Synthesis, kinetic and in silico evaluation as carbonic anhydrase isoforms I, II, IV, and IX inhibitors.
2020 Arch Pharm (Weinheim) Synthesis, characterization, biological evaluation, and molecular docking studies of some piperonyl-based 4-thiazolidinone derivatives.
2019 Dec Proc Biol Sci Characterization of the main steps in first shell formation in iMytilus galloprovincialisi: possible role of tyrosinase.
2019 Dec Med Lett Drugs Ther Drugs for common eye disorders.
2019 Nov Int J Biol Macromol Brinzolamide loaded chitosan-pectin mucoadhesive nanocapsules for management of glaucoma: Formulation, characterization and pharmacodynamic study.
2020 Jan Eur J Med Chem Halogenated and di-stituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms.
2019 PLoS One Effects of insulin signaling on mouse taste cell proliferation.
2020 Jan Eur J Med Chem Direct and straightforward access to stituted alkyl selenols as novel carbonic anhydrase inhibitors.
2020 Mar J Med Chem Bioisosteric Development of Multitarget Nonsteroidal Anti-Inflammatory Drug-Carbonic Anhydrases Inhibitor Hybrids for the Management of Rheumatoid Arthritis.
2019 Oct Diagnostics (Basel) Comparison of Commercial ELISA Kits, a Prototype Multiplex Electrochemoluminescent Assay, and a Multiplex Bead-Based Immunoassay for Detecting a Urine-Based Bladder-Cancer-Associated Diagnostic Signature.
2019 Anal Bioanal Chem Automated and enhanced extraction of a small molecule-drug conjugate using an enzyme-inhibitor interaction based SPME tool followed by direct analysis by ESI-MS.
2020 Br J Pharmacol Carbonic anhydrase II does not regulate nitrite-dependent nitric oxide formation and vasodilation.
2020 Int Ophthalmol Real-life experience of using brinzolamidebrimonidine fixed drop combination in a tertiary glaucoma centre.
2019 Dec J Am Chem Soc Fast Microsecond Dynamics of the Protein-Water Network in the Active Site of Human Carbonic Anhydrase II Studied by Solid-State NMR Spectroscopy.
2020 Oncogene TFAP2C regulates carbonic anhydrase XII in human breast cancer.
2019 Oct Int J Mol Sci Personalized Treatment Response Assessment for Rare Childhood Tumors Using Microcalorimetry-Exemplified by Use of Carbonic Anhydrase IX and Aquaporin 1 Inhibitors.
2020 Exp Physiol Influence of methazolamide on the human control of breathing: A comparison to acetazolamide.
2019 Oct Acta Crystallogr D Struct... Structural comparison of protiated, HD-exchanged and deuterated human carbonic anhydrase IX.
2019 Vestn Oftalmol [Evaluation of the effect of prostaglandin analogues and a carbonic anhydrase inhibitorβ-blocker combination on the ocular blood flow in patients with primary open-angle glaucoma].
2019 Physiol Biochem Zool Blood and Gill Carbonic Anhydrase in the Context of a Chondrichthyan Model of CO2 Excretion.
2019 Ophthalmic Genet Retinal dystrophy associated with a Kizuna (iKIZi) mutation and a predominantly macular phenotype.
2019 Pak J Pharm Sci Moxifloxacin-Ester derivatives: Synthesis, characterization and pharmacological evaluation.
2020 Biochim Biophys Acta Mol ... PI3K inhibition highlights new molecular interactions involved in the skeletogenesis of Paracentrotus lividus embryos.
2019 Circ Heart Fail Adenosine Kinase Inhibition Augments Conducted Vasodilation and Prevents Left Ventricle Diastolic Dysfunction in Heart Failure With Preserved Ejection Fraction.
2019 Sci Adv New power of self-assembling carbonic anhydrase inhibitor: Short peptide-constructed nanofibers inspire hypoxic cancer therapy.
2019 Nov Bioorg Med Chem Synthesis and exploration of 2-morpholino-4-phenylthiazol-5-yl acrylamide derivatives for their effects against carbonic anhydrase I, II, IX and XII isoforms as a non-sulfonamide class of inhibitors.
2019 Bioorg Chem Synthesis, biological evaluation and in silico modelling studies of 1,3,5-tristituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective cancer-associated hCA IX isoenzyme inhibitors.
2019 Bioorg Chem Synthesis and comparative carbonic anhydrase inhibition of new Schiff's bases incorporating benzenesulfonamide, methanesulfonamide, and methylsulfonylbenzene scaffolds.
2019 Sep Sci Rep Engineered Carbonic Anhydrase VI-Mimic Enzyme Switched the Structure and Affinities of Inhibitors.
2019 Expert Rev Neurother Contemporary management of the pseudotumor cerebri syndrome.
2019 Nov Eur J Med Chem From random to rational: A discovery approach to selective nanomolar inhibitors of human carbonic anhydrase IV based on the Castagnoli-Cushman multicomponent reaction.
2019 Nov Eur J Med Chem Structure-activity relationship with pyrazoline-based aromatic sulfamates as carbonic anhydrase isoforms I, II, IX and XII inhibitors: Synthesis and biological evaluation.
2019 Bioorg Chem Pyrazole[3,4-d]pyridazine derivatives: Molecular docking and explore of acetylcholinesterase and carbonic anhydrase enzymes inhibitors as anticholinergics potentials.
2019 PLoS One Role of carbonic anhydrase in acute recovery following renal ischemia reperfusion injury.
2019 Jul ACS Omega Naphthalimide-Based Template for Inhibitor Screening via Cross-Linking and In-Gel Fluorescence: A Case Study against HCA II.