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Recent literature: Carbonic anhydrase inhibitor
Date Journal Article title
2019 Aug Expert Opin Ther Pat Treatment of glaucoma and ocular hypertension using rho kinase inhibitors: patent evaluation of US2018244666 and US2018256595.
2019 Aug Expert Opin Drug Discov Advances in the structural annotation of human carbonic anhydrases and impact on future drug discovery.
2019 Feb 5 Acute, Sustained, Intraoc...
2019 J Enzyme Inhib Med Chem Exploring benzoxaborole derivatives as carbonic anhydrase inhibitors: a structural and computational analysis reveals their conformational variability as a tool to increase enzyme selectivity.
2019 Aug Eur J Med Chem Carbonic anhydrase inhibitors based on sorafenib scaffold: Design, synthesis, crystallographic investigation and effects on primary breast cancer cells.
2019 Aug Intern Med J The Addition of Low Dose Acetazolamide as an adjunct in patients undergoing High dose Methotrexate is safe and beneficial.
2019 J Enzyme Inhib Med Chem Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold.
2019 Aug Eur J Med Chem Synthesis of novel tellurides bearing benzensulfonamide moiety as carbonic anhydrase inhibitors with antitumor activity.
2019 Aug Cancers (Basel) Type 1 Sodium Calcium Exchanger Forms a Complex with Carbonic Anhydrase IX and Via Reverse Mode Activity Contributes to pH Control in Hypoxic Tumors.
2019 Nov Anal Chim Acta Capillary isoelectric focusing with free or immobilized pH gradient in silica particles packed column.
2019 Jul Bioorg Chem Synthesis, molecular docking analysis and carbonic anhydrase I-II inhibitory evaluation of new sulfonamide derivatives.
2019 Front Pharmacol Carbonic Anhydrase 1-Mediated Calcification Is Associated With Atherosclerosis, and Methazolamide Alleviates Its Pathogenesis.
2019 J Food Biochem The effects of hesperidin on sodium arsenite-induced different organ toxicity in rats on metabolic enzymes as antidiabetic and anticholinergics potentials: A biochemical approach.
2019 Jul Bioorg Med Chem Evaluation of α-hydroxycinnamic acids as pyruvate carboxylase inhibitors.
2019 Jul Bioorg Chem Ureidobenzenesulfonamides as efficient inhibitors of carbonic anhydrase II.
2019 Jul Polymers (Basel) Amphiphilic Acrylic Nanoparticles Containing the Poloxamer Star Bayfit® 10WF15 as Ophthalmic Drug Carriers.
2019 Jul Cancers (Basel) Harnessing Induced Essentiality: Targeting Carbonic Anhydrase IX and Angiogenesis Reduces Lung Metastasis of Triple Negative Breast Cancer Xenografts.
2019 Front Pharmacol Efficacy and Safety of Brinzolamide as Add-On to Prostaglandin Analogues or β-Blocker for Glaucoma and Ocular Hypertension: A Systematic Review and Meta-Analysis.
2019 Aug J Med Chem Synthesis and Evaluation of Carbonic Anhydrase Inhibitors with Carbon Monoxide Releasing Properties for the Management of Rheumatoid Arthritis.
2019 Semin Ophthalmol A Retrospective Study of Transcleral Cyclophotocoagulation Using the Slow Coagulation Technique for the Treatment of Refractory Glaucoma.
2019 Jun Cancers (Basel) Comparative Transcriptomic Analysis of Temozolomide Resistant Primary GBM Stem-Like Cells and Recurrent GBM Identifies Up-Regulation of the Carbonic Anhydrase iCA2i Gene as Resistance Factor.
2019 Jun Mol Cells Crystal Structure of a Highly Thermostable α-Carbonic Anhydrase from Persephonella marina EX-H1.
2019 PLoS Genet Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL.
2019 Jan StatPearls Ibuprofen
2019 J Ophthalmol Timolol 0.1% in Glaucomatous Patients: Efficacy, Tolerance, and Quality of Life.
2019 May J Biomol Struct Dyn Computational modeling of novel inhibitory peptides targeting proteoglycan like region of carbonic anhydrase IX and iin vitroi validation in HeLa cells.
2019 Sep Eur J Med Chem Benzensulfonamides bearing spyrohydantoin moieties act as potent inhibitors of human carbonic anhydrases II and VII and show neuropathic pain attenuating effects.
2019 May J Allergy Clin Immunol Pract Carbonic anhydrase inhibitor-induced Stevens-Johnson syndrometoxic epidermal necrolysis leads to extensive cutaneous involvement.
2019 Arch Pharm (Weinheim) Synthesis, characterization, molecular docking and biological activities of novel pyrazoline derivatives.
2019 Pflugers Arch Ciliary beating amplitude controlled by intracellular Cl- and a high rate of CO2 production in ciliated human nasal epithelial cells.
2019 May Vet Ophthalmol The effects of topical dorzolamide 2% and brinzolamide 1%, either alone or combined with timolol 0.5%, on intraocular pressure, pupil diameter, and heart rate in healthy cats.
2019 May Chem Commun (Camb) Polypharmacology of epacadostat: a potent and selective inhibitor of the tumor associated carbonic anhydrases IX and XII.
2019 Apr Crit Care Trial sequential analysis suggested the potential overestimated effect of carbonic anhydrase inhibitor for respiratory failure and metabolic alkalosis.
2019 Ophthalmol Retina Macular Hole Closure with Topical Carbonic Anhydrase Inhibitor.
2019 Comput Biol Chem A selectivity study of benzenesulfonamide derivatives on human carbonic anhydrase IIIX by 3D-QSAR, Molecular Docking and Molecular Dynamics Simulation.
2019 Apr Int J Mol Sci Pain Relieving Effect of-NSAIDs-CAIs Hybrid Molecules: Systemic and Intra-Articular Treatments against Rheumatoid Arthritis.
2019 Front Neurol Brain Edema Formation and Functional Outcome After Surgical Decompression in Murine Closed Head Injury Are Modulated by Acetazolamide Administration.
2019 Apr ACS Nano Quercetin-Modified Metal-Organic Frameworks for Dual Sensitization of Radiotherapy in Tumor Tissues by Inhibiting the Carbonic Anhydrase IX.
2019 Methods Mol Biol Thermodynamic and Kinetic Analysis of Isothermal Titration Calorimetry Experiments by Using KinITC in AFFINImeter.
2019 Apr J Med Chem Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma.
2019 Bioorg Chem Design, synthesis, and carbonic anhydrase inhibition activity of benzenesulfonamide-linked novel pyrazoline derivatives.
2019 Apr Carbohydr Res Synthesis of saccharin-glycoconjugates targeting carbonic anhydrase using a one-pot cyclizationdeprotection strategy.
2019 AoB Plants Photosynthetic acclimation of terrestrial and merged leaves in the amphibious plant iHygrophila difformisi.
2019 Mar Am J Ophthalmol Effect of Topical Hypotensive Medications for Preventing Intraocular Pressure Increase after Cataract Surgery in Eyes with Glaucoma.
2019 Biochimie Highly active extracellular α-class carbonic anhydrase of Cyanothece sp. ATCC 51142.
2019 Apr Mol Pharm Development of the 99mTc-Hydroxamamide Complex as a Probe Targeting Carbonic Anhydrase IX.
2019 Bioorg Chem Synthesis of benzensulfonamides linked to quinazoline scaffolds as novel carbonic anhydrase inhibitors.
2019 Mar Int J Mol Sci Novel 8-Substituted Coumarins That Selectively Inhibit Human Carbonic Anhydrase IX and XII.
2019 Mar Acta Crystallogr F Struct... Carbonic anhydrase II in complex with carboxylic acid-based inhibitors.
2019 J Enzyme Inhib Med Chem Evaluation of the anticancer potential of a sulphonamide carbonic anhydrase IX inhibitor on cervical cancer cells.
2019 Mini Rev Med Chem Pharmacophores Modeling in Terms of Prediction of Theoretical Physicochemical Properties and Verification by EXPERIMENTAL correlations of Carbacylamidophosphates (CAPh) and Sulfanylamidophosphates (SAPh) Tested as New Carbonic Anhydrase Inhibitors.
2019 Mar Life Sci Glaucoma: Current treatment and impact of advanced drug delivery systems.
2019 PLoS One Oculohypotensive effects of various acetozolamide nanopreparations for topical treatment of animal model-induced glaucoma and their impact on optic nerve.
2019 eNeuro Modes of Accessing Bicarbonate for the Regulation of Membrane Guanylate Cyclase (ROS-GC) in Retinal Rods and Cones.
2018 Afr Health Sci Inhibition of cell proliferation, migration and colony formation of LS174T Cells by carbonic anhydrase inhibitor.
2019 Bioorg Chem Design, synthesis and biological evaluation of coumarin-3-carboxamides as selective carbonic anhydrase IX and XII inhibitors.
2019 J Bioenerg Biomembr Carbonic anhydrase-IX inhibition enhances the efficacy of hexokinase II inhibitor for hepatocellular carcinoma in a murine model.
2019 Bioorg Chem Discovery of new organoselenium compounds as antileishmanial agents.
2019 Oncol Rep Cellular and radiobiological effects of carbonic anhydrase IX in human breast cancer cells.
2019 Bioorg Chem Benzenesulfonamides incorporating nitrogenous bases show effective inhibition of β-carbonic anhydrases from the pathogenic fungi Cryptococcus neoformans, Candida glabrata and Malassezia globosa.
2019 Feb J Struct Biol Using neutron crystallography to elucidate the basis of selective inhibition of carbonic anhydrase by saccharin and a derivative.
2019 Bioorg Chem Synthesis and biological evaluation of novel tris-chalcones as potent carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and α-glycosidase inhibitors.
2019 Jan Fluids Barriers CNS Disruption of the hippocampal and hypothalamic blood-brain barrier in a diet-induced obese model of type II diabetes: prevention and treatment by the mitochondrial carbonic anhydrase inhibitor, topiramate.
2019 Arch Pharm (Weinheim) Microwave-assisted synthesis of 1-stituted-1H-benzimidazolium salts: Non-competitive inhibition of human carbonic anhydrase I and II.
2019 Aging Cell Sirt1-hypoxia-inducible factor-1α interaction is a key mediator of tubulointerstitial damage in the aged kidney.
2019 Bioorg Chem Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity.
2019 FASEB J Genetic mutation of Kcnj16 identifies Kir5.1-containing channels as key regulators of acute and chronic pH homeostasis.
2019 Arch Pharm (Weinheim) Aminopyrazole-stituted metallophthalocyanines: Preparation, aggregation behavior, and investigation of metabolic enzymes inhibition properties.
2019 J Biochem Mol Toxicol Evaluation of antimicrobial, antibiofilm and carbonic anhydrase inhibition profiles of 1,3-bis-chalcone derivatives.
2019 Expert Opin Ther Pat Targeted treatment of anaerobic cancer. Patent evaluation of US2016279084 and US2017056350.
2018 Dec Invest Ophthalmol Vis Sci Prospective Evaluation of Patients With X-Linked Retinoschisis During 18 Months.
2019 J Fr Ophtalmol [Selective laser trabeculoplasty in African blacks].
2018 Dec Int J Mol Sci Sulfonamide Inhibition Studies of a New β-Carbonic Anhydrase from the Pathogenic Protozoan iEntamoeba histolyticai.
2019 J Plant Physiol The presence of the low molecular mass carbonic anhydrase in photosystem II of C3 higher plants.
2019 J Biochem Mol Toxicol Synthesis and characterization of novel stituted thiophene derivatives and discovery of their carbonic anhydrase and acetylcholinesterase inhibition effects.