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Recent literature: Muscarinic receptor antagonist
Date Journal Article title
2020 Mar eNeuro Muscarinic-Dependent miR-182 and QR2 Expression Regulation in the Anterior Insula Enables Novel Taste Learning.
2020 Mar Adv Ther New Perspectives for Mucolytic, Anti-inflammatory and Adjunctive Therapy with 1,8-Cineole in COPD and Asthma: Review on the New Therapeutic Approach.
2020 Mar Ann N Y Acad Sci Diagnostics and treatment of nerve agent poisoning-current status and future developments.
2020 Mar Mol Neurobiol Muscarinic Toxin 7 Signals Via Ca2+Calmodulin-Dependent Protein Kinase Kinase β to Augment Mitochondrial Function and Prevent Neurodegeneration.
2020 Mar Behav Brain Res Better antidepressant efficacy of mecamylamine in combination with L-NAME than with L-arginine.
2020 Mar Neuropharmacology α7 nicotinic acetylcholine receptors as therapeutic targets in schizophrenia: Update on animal and clinical studies and strategies for the future.
2020 Mar Epilepsy Behav Fenfluramine acts as a positive modulator of sigma-1 receptors.
2020 Mar Br J Pharmacol The effect of maslinic acid on cognitive dysfunction induced by cholinergic blockade in mice.
2020 Mar Biomol Ther (Seoul) The Altered Signaling on EFS-Induced Colon Contractility in Diabetic Rats.
2020 Ther Adv Respir Dis Efficacy and safety of revefenacin for nebulization in patients with chronic obstructive pulmonary disease taking concomitant ICSLABA or LABA: group analysis from phase III trials.
2020 Feb Anticancer Drugs Activation of muscarinic acetylcholine receptor 1 promotes invasion of hepatocellular carcinoma by inducing epithelial-mesenchymal transition.
2020 Feb Respir Investig Inhibitory effects of glycopyrronium, formoterol, and budesonide on coronavirus HCoV-229E replication and cytokine production by primary cultures of human nasal and tracheal epithelial cells.
2020 Feb Brain Sci The Impact of Removal of Ovarian Hormones on Cholinergic Muscarinic Receptors: Examining Prepulse Inhibition and Receptor Binding.
2020 Mar ACS Chem Neurosci Structure-Activity Relationship Study of Psychostimulant Synthetic Cathinones Reveals Nanomolar Antagonist Potency of α-Pyrrolidinohexiophenone at Human Muscarinic M2 Receptors.
2020 Feb J Cell Biochem M3 receptor modulates extracellular matrix synthesis via ERK12 signaling pathway in human bladder smooth muscle cells.
2020 Apr Biochem Biophys Res Commun Breakdown of phospholipids and the elevated nitric oxide are involved in M3 muscarinic regulation of acetylcholine secretion in the frog motor synapse.
2020 Jan BMC Complement Med Ther The use of Euphorbia hirta L. (Euphorbiaceae) in diarrhea and constipation involves calcium antagonism and cholinergic mechanisms.
2020 Feb Chem Senses Neuropeptide S displays as a key neuromodulator in olfactory spatial memory.
2019 Pharmacol Rep Muscarinic M1 and M2 receptor types play opposite roles in LPS-induced septic shock.
2019 Pharmacol Rep Cryptostrobin and catechin isolated from Eugenia mattosii D. Legrand leaves induce endothelium-dependent and independent relaxation in spontaneously hypertensive rat aorta.
2020 May Gen Comp Endocrinol Mechanism of gamete shedding in starfish: Involvement of acetylcholine in extracellular Ca2+-dependent contraction of gonadal walls.
2020 Expert Opin Pharmacother The pharmacological management of asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS).
2020 Expert Rev Clin Pharmacol Aclidinium bromide and formoterol fumarate for the maintenance treatment of chronic obstructive pulmonary disease.
2020 Jan Inflammation Anti-arthritic Effect of the Spirocyclopiperazinium Salt Compound LXM-15 in Rats and Its Underlying Mechanism.
2020 Jan Int J Mol Sci PIP2 Mediated Inhibition of TREK Potassium Currents by Bradykinin in Mouse Sympathetic Neurons.
2020 Arch Oral Biol α7-Nicotine acetylcholine receptor mediated nicotine induced cell survival and cisplatin resistance in oral cancer.
2020 Mar Eur J Pharmacol The muscarinic receptor antagonist tolterodine inhibits voltage-dependent K+ channels in rabbit coronary arterial smooth muscle cells.
2020 Respir Med One-year follow up of asthmatic patients newly initiated on treatment with medium- or high-dose inhaled corticosteroid-long-acting β2-agonist in UK primary care settings.
2020 J Pharmacol Exp Ther Dorsoventral-Specific Effects of Nerve Agent Surrogate Diisopropylfluorophosphate on Synaptic Transmission in the Mouse Hippocampus.
2019 Dec Behav Pharmacol The contribution of orexin receptors within the ventral tegmental area to modulation of antinociception induced by chemical stimulation of the lateral hypothalamus in the animal model of orofacial pain in the rats.
2020 Pflugers Arch Modulation of hypercapnic respiratory response by cholinergic transmission in the commissural nucleus of the solitary tract.
2020 Mar Toxicol Sci Characterization of Cholinesterases From Multiple Large Animal Species for Medical Countermeasure Development Against Chemical Warfare Nerve Agents.
2020 Jan Neuroreport Possible interaction between the ventral hippocampal cannabinoid CB2 and muscarinic acetylcholine receptors on the modulation of memory consolidation in mice.
2019 Bratisl Lek Listy The effects and mechanisms of the action of galangin on spatial memory in rats.
2020 Jan ACS Chem Neurosci Discovery of Procognitive Antipsychotics by Combining Muscarinic M1 Receptor Structure-Activity Relationship with Systems Response Profiles in Zebrafish Larvae.
2019 Front Pharmacol Choline Attenuates Cardiac Fibrosis by Inhibiting p38MAPK Signaling Possibly by Acting on M3 Muscarinic Acetylcholine Receptor.
2020 J Pharmacol Sci Muscarinic M1 receptors stimulated by intracerebroventricular administration of McN-A-343 reduces the nerve injury-induced mechanical hypersensitivity via GABAB receptors rather than GABAA receptors in mice.
2019 Dec Neurosci Res Dopamine D1 and muscarinic acetylcholine receptors in dorsal striatum are required for high speed running.
2020 Mol Cell Biochem Ephx2-gene deletion affects acetylcholine-induced relaxation in angiotensin-II infused mice: role of nitric oxide and CYP-epoxygenases.
2020 Drugs Real World Outcomes Comparative Causal Analysis of the Effects of Long-Acting Muscarinic Antagonist Versus No Long-Acting Bronchodilator Use on Readmission or Mortality After Hospitalization for Chronic Obstructive Pulmonary Disease.
2020 Jan Brain Res Loss of endogenous analgesia leads to delayed recovery from incisional pain in a rat model of chronic neuropathic pain.
2019 Nov Sci Rep Zn2+ stimulates salivary secretions via metabotropic zinc receptor ZnRGPR39 in human salivary gland cells.
2019 Nov Low Urin Tract Symptoms Effects of combined treatment with fesoterodine and mirabegron in a pelvic congestion rat model: Results from in vitro and in vivo functional studies.
2020 Int J Clin Pharmacol Ther Safety of the muscarinic receptor-antagonist (R,R)-penehyclidine fumarate in healthy jects: A phase 1 randomized, double-blind, single-dose escalation study
.
2019 Arerugi [PREVALENCE OF FUNCTIONAL DYSPEPSIA SYMPTOMS IN PATIENTS WITH ASTHMA].
2019 FP Essent Respiratory Conditions: Chronic Obstructive Pulmonary Disease.
2019 Evodevo Characterization of nAChRs in iNematostella vectensisi ports neuronal and non-neuronal roles in the cnidarian-bilaterian common ancestor.
2019 Nov Sci Rep The beneficial effects of a muscarinic agonist on pancreatic β-cells.
2019 Nov Exp Clin Endocrinol Diabetes 3-Iodothyronamine Induces Diverse Signaling Effects at Different Aminergic and Non-Aminergic G-Protein Coupled Receptors.
2020 Feb Behav Brain Res Rewarding effects of M4 but not M3 muscarinic cholinergic receptor antagonism in the rostromedial tegmental nucleus.
2020 Basic Clin Pharmacol Toxicol Pre-clinical evidence of safety and protective effect of isatin and oxime derivatives against malathion-induced toxicity.
2019 Neurochem Res Antinociceptive Effect of Spirocyclopiperazinium Salt Compound DXL-A-24 and the Underlying Mechanism.
2020 Feb Behav Brain Res Blockade of muscarinic acetylcholine receptor by scopolamine impairs the memory formation of filial imprinting in domestic chicks (Gallus Gallus domesticus).
2019 Pharmacol Biochem Behav d-Cycloserine reverses scopolamine-induced object and place memory deficits in a spontaneous recognition paradigm in rats.
2019 Adv Ther Optimizing the Development Strategy of Combination Therapy in Respiratory Medicine: From Isolated Airways to Patients.
2019 Pharmacol Rep Muscarinic M1 and M2 receptor types play opposite roles in LPS-induced septic shock.
2019 J Asthma Allergy Characterizing Real-World Use Of Tiotropium In Asthma In The USA.
2020 Eur J Neurosci Dorsal hippocampus cholinergic and nitrergic neurotransmission modulates the cardiac baroreflex function in rats.
2019 Oct JCI Insight Muscarinic receptors promote pacemaker fate at the expense of secondary conduction system tissue in zebrafish.
2019 Dec Toxicol Appl Pharmacol Tiotropium bromide, a long acting muscarinic receptor antagonist triggers intracellular calcium signalling in the heart.
2019 Oct Int J Mol Sci Beneficial Effects of Neurotensin in Murine Model of Hapten-Induced Asthma.
2019 Neurochem Res A Selective M1 and M3 Receptor Antagonist, Penehyclidine Hydrochloride, Exerts Antidepressant-Like Effect in Mice.
2019 Dec J Neurophysiol Muscarinic acetylcholine receptor-dependent persistent activity of layer 5 intrinsic-bursting and regular-spiking neurons in primary auditory cortex.
2019 Pharmacol Biochem Behav Strain differences in muscarinic cholinergic receptor antagonism of fat intake and acquisition and expression of fat-conditioned flavor preferences in male BALBc, C57BL6 and SWR mice.
2019 Cell Physiol Biochem JAK2STAT3 Pathway is Required for α7nAChR-Dependent Expression of POMC and AGRP Neuropeptides in Male Mice.
2019 J Pharm Pharmacol Effects of myricetin-3-O-α-rhamnoside (myricitrin) treatment on urinary parameters of Wistar rats.
2020 Jan Gen Comp Endocrinol Identification of pheasant ghrelin and motilin and their actions on contractility of the isolated gastrointestinal tract.
2019 Int J Chron Obstruct Pulm... Imidafenacin, An Orally Active Muscarinic Receptor Antagonist, Improves Pulmonary Function In Patients With Chronic Obstructive Pulmonary Disease: A Multicenter, Randomized, Double-Blind, Placebo-Controlled 3×3 Crossover Phase II Trial.
2019 Sep Sci Rep M1 muscarinic receptor is a key target of neuroprotection, neuroregeneration and memory recovery by i-Extract from Withania somnifera.
2019 Sep Sci Transl Med Muscarinic acetylcholine receptor regulates self-renewal of early erythroid progenitors.
2019 Front Pharmacol Pharmacological Modulation of Endotoxin-Induced Release of IL-26 in Human Primary Lung Fibroblasts.
2020 J Surg Res α7 Nicotinic Acetylcholine Receptor Mediates the Neuroprotection of Remote Ischemic Postconditioning in a Rat Model of Asphyxial Cardiac Arrest.
2019 Surg Oncol Acetylcholine receptors: Key players in cancer development.
2019 Int J Chron Obstruct Pulm... Real-world effectiveness of umeclidiniumvilanterol versus fluticasone propionatesalmeterol as initial maintenance therapy for chronic obstructive pulmonary disease (COPD): a retrospective cohort study.
2019 Sep Mar Drugs Structure-Function Elucidation of a New α-Conotoxin, MilIA, from iConus milneedwardsii.