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Recent literature: Muscarinic receptor antagonist
Date Journal Article title
2019 Feb Sci Rep Phencynonate S-isomer as a eutomer is a novel central anticholinergic drug for anti-motion sickness.
2019 Feb Brain Res Layer-specific involvement of endocannabinoid signaling in muscarinic-induced long-term depression in layer 23 pyramidal neurons of rat visual cortex.
2019 Feb Neurotox Res Mechanism Underlying Organophosphate Paraoxon-Induced Kinetic Tremor.
2018 eNeuro Cell Type- and Layer-Specific Muscarinic Potentiation of Excitatory Synaptic Drive onto Parvalbumin Neurons in Mouse Prefrontal Cortex.
2019 Feb Drug Dev Ind Pharm Nicotine-like discriminative stimulus effects of acetylcholinesterase inhibitors and a muscarinic receptor agonist in rhesus monkeys.
2019 Jan Neuroscience Augmentation of Endogenous Acetylcholine Uptake and Cholinergic Facilitation of Hippocampal Long-Term Potentiation by Acetylcholinesterase Inhibition.
2019 Jan Neurobiol Dis Trihexyphenidyl rescues the deficit in dopamine neurotransmission in a mouse model of DYT1 dystonia.
2018 Pestic Biochem Physiol Pharmacology of central octopaminergic and muscarinic pathways in Drosophila melanogaster larvae: Assessing the target potential of GPCRs.
2019 Jan Brain Res Commonalities and differences in extracellular levels of hippocampal acetylcholine and amino acid neurotransmitters during status epilepticus and sequent epileptogenesis in two rat models of temporal lobe epilepsy.
2019 Jan Clin Exp Optom Alpha2 -adrenoceptor agonists inhibit form-deprivation myopia in the chick.
2019 Jan Pharmaceuticals (Basel) On the Absolute Stereochemistry of Tolterodine: A Circular Dichroism Study.
2019 Jan mSphere Repurposing Pilocarpine Hydrochloride for Treatment of Candida albicans Infections.
2019 Int J Chron Obstruct Pulm... A randomized trial to determine the impact of indacaterolglycopyrronium on nighttime oxygenation and symptoms in patients with moderate-to-severe COPD: the DuoSleep study.
2019 Jan Chest Adding a LAMA to ICSLABA Therapy: A Meta-analysis of Triple Therapy in COPD.
2019 Eur Rev Med Pharmacol Sci Aclidinium bromide inhibits proliferation of osteosarcoma cells through regulation of PI3KAkt pathway.
2019 Jan Int J Mol Sci The Effect of Dexamethasone, Adrenergic and Cholinergic Receptor Agonists on Phospholipid Metabolism in Human Osteoarthritic Synoviocytes.
2019 Jan Neurosci Lett Acetylcholine presses the increase of glia fibrillary acidic protein expression via acetylcholine receptors in cAMP-induced astrocytic differentiation of rat C6 glioma cells.
2019 PLoS One In vitro anti-inflammatory effects of AZD8999, a novel bifunctional muscarinic acetylcholine receptor antagonist β2-adrenoceptor agonist (MABA) compound in neutrophils from COPD patients.
2018 Int J Chron Obstruct Pulm... Triple therapy (ICSLABALAMA) in COPD: time for a reappraisal.
2018 Dec Biomed Pharmacother Vasorelaxant and antihypertensive effects of Tianshu Capsule on rats: An in vitro and in vivo approach.
2019 Jan Food Funct Theanine attenuates memory impairments induced by klotho gene depletion in mice.
2019 Tuberc Respir Dis (Seoul) Expression of Muscarinic Receptors and the Effect of Tiotropium Bromide in Aged Mouse Model of Chronic Asthma.
2018 Dec BMC Anesthesiol Tramadol for the treatment of catheter-related bladder discomfort: a randomized controlled trial.
2018 Dec Cancer Chemother Pharmacol Prophylactic effect of scopolamine butylbromide, a competitive antagonist of muscarinic acetylcholine receptor, on irinotecan-related cholinergic syndrome.
2019 Feb Bioorg Med Chem Lett Muscarinic agonist, (±)-quinuclidin-3-yl-(4-fluorophenethyl)(phenyl)carbamate: High affinity, but low type selectivity for human M1 - M5 muscarinic acetylcholine receptors.
2018 Dec Respir Res Spirometric changes during exacerbations of COPD: a post hoc analysis of the WISDOM trial.
2018 Dec Psychiatry Res BDNF mediates the protective effects of scopolamine in reserpine-induced depression-like behaviors via up-regulation of 5-HTT and TPH1.
2018 Dec J Psychopharmacol Overnight transdermal scopolamine patch administration has no clear effect on cognition and emotional processing in healthy volunteers.
2019 Jan Eur J Pharmacol Pharmacological characterization of DA-8010, a novel muscarinic receptor antagonist selective for urinary bladder over salivary gland.
2018 Nov Psychiatry Res Electro convulsive therapy: Modification of its effect on the autonomic nervous system using anti-cholinergic drugs.
2018 Nov Neuropsychopharmacology Blockade of muscarinic acetylcholine receptors facilitates motivated behaviour and rescues a model of antipsychotic-induced amotivation.
2018 Medicine (Baltimore) Treatment of chronic obstructive pulmonary disease in patients with different fractional exhaled nitric oxide levels.
2018 Nov Oncogenesis Muscarinic acetylcholine receptor 3 mediates vagus nerve-induced gastric cancer.
2018 Cancer Cell Int M3 muscarinic acetylcholine receptors regulate epithelial-mesenchymal transition, perineural invasion, and migrationmetastasis in cholangiocarcinoma through the AKT pathway.
2019 Pharmacol Biochem Behav The role of dopamine D1- and D2-like receptors related to muscarinic M1 receptors in impulsive choice in high-impulsive and low-impulsive rats.
2018 Nat Chem Biol Structural insights into the type-selective antagonist binding to the M2 muscarinic receptor.
2019 Jan Biomol Ther (Seoul) The Inhibitory Mechanism on Acetylcholine-Induced Contraction of Bladder Smooth Muscle in the Streptozotocin-Induced Diabetic Rat.
2018 Nov Proc Natl Acad Sci U S A Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists.
2018 Biomed Pharmacother Diosmin is neuroprotective in a rat model of scopolamine-induced cognitive impairment.
2018 Peptides BJ-PRO-7A and BJ-PRO-10C induce vasodilatation and inotropic effects in normotensive and hypertensive rats: Role of nitric oxide and muscarinic receptors.
2019 Feb Brain Res Stimulating muscarinic M1 receptors in the anterior cingulate cortex reduces mechanical hypersensitivity via GABAergic transmission in nerve injury rats.
2018 Oct Disaster Med Public Healt... Contingency Medical Countermeasures for Mass Nerve-Agent Exposure: Use of Pharmaceutical Alternatives to Community Stockpiled Antidotes.
2018 Dec Eur J Med Chem Discovery, cocrystallization and biological evaluation of novel piperidine derivatives as high affinity Ls-AChBP ligands possessing α7 nAChR activities.
2018 Oct Braz J Med Biol Res Acute exercise inhibits gastric emptying of liquids in rats: influence of the NO-cGMP pathway.
2018 Oct Int J Mol Sci Prostaglandin D₂ Induces Ca2+ Sensitization of Contraction without Affecting Cytosolic Ca2+ Level in Bronchial Smooth Muscle.
2018 Sep BMC Res Notes Modulation of CaV1.3b L-type calcium channels by M1 muscarinic receptors varies with CaVβ unit expression.
2018 Jan StatPearls Glycopyrrolate
2018 Neuropharmacology Muscarinic receptor antagonists activate ERK-CREB signaling to augment neurite outgrowth of adult sensory neurons.
2018 Expert Opin Pharmacother An evaluation of memantine ER + donepezil for the treatment of Alzheimer's disease.
2018 Eur J Neurosci Striatal cholinergic interneurons regulate cognitive and affective dysfunction in partially dopamine-depleted mice.
2018 Sep Cell Rep Dual Dopaminergic Regulation of Corticostriatal Plasticity by Cholinergic Interneurons and Indirect Pathway Medium Spiny Neurons.
2018 Int J Chron Obstruct Pulm... Dual bronchodilation vs triple therapy in the "real-life" COPD DACCORD study.
2018 Expert Opin Pharmacother Challenges in the management of asthma associated with smoking-induced airway diseases.
2018 Cell Physiol Biochem Activation of M3 Muscarinic Acetylcholine Receptors Delayed Cardiac Aging by Inhibiting the Caspase-1IL-1β Signaling Pathway.
2018 Rev Med Liege [Trimbow® : twice-daily triple combination for the treatment of COPD].
2018 Korean J Physiol Pharmacol The change of signaling pathway on the electrical stimulated contraction in streptozotocin-induced bladder dysfunction of rats.
2018 Eur J Pharm Biopharm Time-dependent effects on small intestinal transport by absorption-modifying excipients.
2018 Respir Med Clinical characteristics and medication patterns in patients with COPD prior to initiation of triple therapy with ICSLAMALABA: A retrospective study.
2018 Aug Phytomedicine Total phenolic and flavonoid contents and antihypertensive effect of the crude extract and fractions of Calamintha vulgaris.
2018 Neuropharmacology The potential antidepressant action and adverse effects profile of scopolamine co-administered with the mGlu7 receptor allosteric agonist AMN082 in mice.
2018 Pharmacol Rep GABAA receptor in the Pedunculopontine tegmental (PPT) nucleus: Effects on cardiovascular system.
2018 Int J Chron Obstruct Pulm... Management of severe COPD exacerbations: focus on beclomethasone dipropionateformoterolglycopyrronium bromide.
2018 J Pharmacol Sci Involvement of GABAB receptor in the antihypersensitive effect in anterior cingulate cortex of partial sciatic nerve ligation model.
2018 Psychopharmacology (Berl) 5-HT1A parital agonism and 5-HT7 antagonism restore episodic memory in chronic phencyclidine-treated mice: role of brain glutamate, dopamine, acetylcholine and GABA.
2018 Oct Int J Pharm Effect of absorption-modifying excipients, hypotonicity, and enteric neural activity in an in vivo model for small intestinal transport.
2018 Chin J Nat Med Neuroprotective effect of the ethanol extract of Artemisia capillaris on transient forebrain ischemia in mice via nicotinic cholinergic receptor.
2018 J Pharmacol Sci Varenicline is a smoking cessation drug that blocks alveolar expansion in mice intratracheally administrated porcine pancreatic elastase.
2018 Oct Toxicol Lett Placental mechanism of prenatal nicotine exposure-reduced blood cholesterol levels in female fetal rats.
2018 Brain Res Bull The memory-enhancing effects of 7,8,4'-trihydroxyisoflavone, a major metabolite of daidzein, are associated with activation of the cholinergic system and BDNF signaling pathway in mice.
2018 Asian J Androl Muscarinic acetylcholine receptor M1 mediates prostate cancer cell migration and invasion through hedgehog signaling.
2017 Oct ACS Omega Heterodimerization of Dibenzodiazepinone-Type Muscarinic Acetylcholine Receptor Ligands Leads to Increased M2R Affinity and Selectivity.
2018 Acta Neurobiol Exp (Wars) Administration of muscarinic antagonists induce changes in passive avoidance learning and in synaptic transmission in the CA1 area of the hippocampus.
2018 Jul Nutrients iStachys sieboldiii Extract Supplementation Attenuates Memory Deficits by Modulating BDNF-CREB and Its Downstream Molecules, in Animal Models of Memory Impairment.
2018 Cell Physiol Biochem VEGF-A and VEGF-B Coordinate the Arteriogenesis to Repair the Infarcted Heart with Vagus Nerve Stimulation.
2018 Sep Eur J Pharmacol Evaluation of the antinociceptive and anti-inflammatory activities of piperic acid: Involvement of the cholinergic and vanilloid systems.