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Recent literature: Muscarinic receptor antagonist
Date Journal Article title
2019 Aug Biochem Pharmacol M3 Muscarinic receptor activation reduces hepatocyte lipid accumulation via CaMKKβAMPK pathway.
2019 Heliyon Evaluation of antiamnesic activity of iSalvia multicaulisi essential oil on scopolamine-induced amnesia in rats: iin vivoi and iin silicoi approaches.
2019 Aug J Ethnopharmacol Elucidation of the possible mechanism of analgesic action of methanol stem bark extract of Uapaca togoensis pax in mice.
2019 Aug Am J Physiol Gastrointest... Optogenetic analysis of neuromuscular transmission in the colon of ChAT-ChR2-YFP BAC transgenic mice.
2019 Aug Int Immunopharmacol Cholinergic system is involved in the therapeutic effect of madecassoside on collagen-induced arthritis in rats.
2019 Aug Life Sci R2-8018 reduces the proliferation and migration of non-small cell lung cancer cells by disturbing transactivation between M3R and EGFR.
2019 Aug J Oral Biosci Novel effects of rooibos extract on tear and saliva secretion mediated by the muscarinic acetylcholine receptor 3 in mice.
2019 Aug Neurobiol Learn Mem Corticolimbic analysis of microRNAs and protein expressions in scopolamine-induced memory loss under stress.
2019 Aug Hypertension Soluble Prorenin Receptor Increases Blood Pressure in High Fat-Fed Male Mice.
2019 Aug Neuroscience Scopolamine and Medial Frontal Stimulus-Processing during Interval Timing.
2019 Jul Sci Rep Role of corticotropin-releasing factor on bladder function in rats with psychological stress.
2019 Aug Neuroscience Cholinergic Receptor Blockade in the VTA Attenuates Cue-Induced Cocaine-Seeking and Reverses the Anxiogenic Effects of Forced Abstinence.
2019 Aug Psychiatry Res Neuroimaging Influence of muscarinic M1 receptor antagonism on brain choline levels and functional connectivity in medication-free jects with psychosis: A placebo controlled, cross-over study.
2019 Front Cell Neurosci Acetylcholine Release Inhibits Distinct Excitatory Inputs Onto Hippocampal CA1 Pyramidal Neurons via Different Cellular and Network Mechanisms.
2019 Jun Behav Neurosci Development of an "object category recognition" task for mice: Involvement of muscarinic acetylcholine receptors.
2019 Apr Cureus The Role of Revefenacin in Chronic Obstructive Pulmonary Disease.
2019 Aug Biochem Biophys Res Commun Muscarinic acetylcholine receptors regulate the dephosphorylation of eukaryotic translation elongation factor 2 in SNU-407 colon cancer cells.
2019 Jun Br J Dermatol Safety and efficacy of topical formulations containing 0.5, 1 and 2% glycopyrronium bromide in patients with primary axillary hyperhidrosis: a randomised, double-blind, placebo-controlled study.
2019 Br J Anaesth A systematic review of rescue analgesic strategies in acute exacerbations of primary trigeminal neuralgia.
2019 Aug Bioorg Med Chem Chemical modification-mediated optimisation of bronchodilatory activity of mepenzolate, a muscarinic receptor antagonist with anti-inflammatory activity.
2019 Jun Digestion The Traditional Medicine Banhasasim-Tang Depolarizes Pacemaker Potentials of Cultured Interstitial Cells of Cajal through M3 Muscarinic and 5-HT3 Receptors in Murine Small Intestine.
2019 Jun Aging (Albany NY) Real-world effectiveness of medications on survival in patients with COPD-heart failure overlap.
2019 Apr Biol Psychiatry Cholinergic Modulation of Exposure Disrupts Hippocampal Processes and Augments Extinction: Proof-of-Concept Study With Social Anxiety Disorder.
2019 Jul ChemMedChem Novel BQCA- and TBPB-Derived M1 Receptor Hybrid Ligands: Orthosteric Carbachol Differentially Regulates Partial Agonism.
2019 J Labelled Comp Radiopharm A convenient synthesis of the muscarinic cholinergic antagonist (R)-[N-methyl-3 H]quinuclidinyl benzilate methiodide.
2019 Jun J Chem Inf Model Heterogeneous Dielectric Implicit Membrane Model for the Calculation of MMPBSA Binding Free Energies.
2019 Front Cell Neurosci Spontaneous and Acetylcholine Evoked Calcium Transients in the Developing Mouse Utricle.
2019 J BUON Aclidinium Bromide holds promising inhibitory effects in A549 lung cancer cells potentials by regulating PI3K AKT signaling pathway.
2019 Ther Adv Respir Dis Aclidinium bromide in fixed-dose combination with formoterol fumarate in the management of COPD: an update on the evidence base.
2019 May Hippocampus Place cell assemblies remain intact, despite reduced phase precession, after cholinergic disruption.
2019 J Pharmacol Exp Ther Pharmacological Profile of AZD8871 (LAS191351), a Novel Inhaled Dual M3 Receptor Antagonistiβi 2-Adrenoceptor Agonist Molecule with Long-Lasting Effects and Favorable Safety Profile.
2018 Pharm Biol Effect of hydroalcoholic Echium amoenum extract on scopolamine-induced learning and memory impairment in rats.
2019 Psychopharmacology (Berl) Matured hop bitter acids improve spatial working and object recognition memory via nicotinic acetylcholine receptors.
2019 Naunyn Schmiedebergs Arch... Novel choline analog 2-(4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazin-1-yl)ethan-1-ol produces sympathoinhibition, hypotension, and antihypertensive effects.
2019 Neuropeptides Excitatory effect of bradykinin on intrinsic neurons of the rat heart.
2019 Jun Neuroscience Effects of Muscarinic Acetylcholine m1 and m4 Receptor Blockade on Dyskinesia in the Hemi-Parkinsonian Rat.
2019 Ther Adv Respir Dis The once-daily fixed-dose combination of olodaterol and tiotropium in the management of COPD: current evidence and future prospects.
2019 Apr Molecules Potential Pharmacokinetic Drug⁻Drug Interaction Between Harmine, a Cholinesterase Inhibitor, and Memantine, a Non-Competitive iNi-Methyl-d-Aspartate Receptor Antagonist.
2019 Apr Mol Med Inhibition of HMGB1RAGE-mediated endocytosis by HMGB1 antagonist box A, anti-HMGB1 antibodies, and cholinergic agonists presses inflammation.
2019 Apr Sci Rep Neural anti-inflammatory action mediated by two types of acetylcholine receptors in the small intestine.
2019 Curr Pharm Des Therapeutic Effect of Novel Antidepressant Drugs Acting at Specific Receptors of Neurotransmitters and Neuropeptides.
2019 Apr Molecules Design, Synthesis, and In Vitro Biological Activities of a Bio-Oxidizable Prodrug to Deliver Both ChEs and DYRK1A Inhibitors for AD Therapy.
2019 Mar Int J Mol Sci Effects of Motilin Receptor Agonists and Ghrelin in Human imotilin receptori Transgenic Mice.
2019 Int J Chron Obstruct Pulm... Randomized dose-finding study of batefenterol via dry powder inhaler in patients with COPD.
2019 Jun Toxicol Lett The arrhythmogenic potential of nerve agents and a cardiac safety profile of antidotes - A proof-of-concept study using human induced pluripotent stem cells derived cardiomyocytes (hiPSC-CM).
2019 PLoS One TAK-071, a muscarinic M1 receptor positive allosteric modulator, attenuates scopolamine-induced quantitative electroencephalogram power spectral changes in cynomolgus monkeys.
2019 Neurobiol Learn Mem Estrous cycle stage gates sex differences in prefrontal muscarinic control of fear memory formation.
2019 Apr Life Sci Role of ambrisentan (selective endothelin-A receptor antagonist) on cigarette smoke exposure induced cognitive impairment in Danio rerio.
2019 Mar Cochrane Database Syst Rev Once daily long-acting beta2-agonists and long-acting muscarinic antagonists in a combined inhaler versus placebo for chronic obstructive pulmonary disease.
2019 Pharmacol Rep Orexin type-2 receptor blockade prevents the nicotine-induced excitation of nucleus accumbens core neurons in rats: An electrophysiological perspective.
2019 J Enzyme Inhib Med Chem Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase.
2019 Expert Rev Clin Pharmacol Revefenacin for the treatment of chronic obstructive pulmonary disease.
2019 Feb Neurobiol Dis Targeting the glutamatergic system to counteract organophosphate poisoning: A novel therapeutic strategy.
2019 Int J Chron Obstruct Pulm... Early management of COPD: where are we now and where do we go from here? A Delphi consensus project.
2019 Apr Life Sci Cholinergic drugs ameliorate endothelial dysfunction by decreasing O-GlcNAcylation via M3 AChR-AMPK-ER stress signaling.
2019 Pharmacol Rep The muscarinic antagonist gallamine induces proliferation of airway smooth muscle cells regardless of the cell phenotype.
2019 Int J Chron Obstruct Pulm... Changes in COPD inhaler prescriptions in the United Kingdom, 2000 to 2016.
2019 Feb Sci Rep Phencynonate S-isomer as a eutomer is a novel central anticholinergic drug for anti-motion sickness.
2019 Jun Brain Res Layer-specific involvement of endocannabinoid signaling in muscarinic-induced long-term depression in layer 23 pyramidal neurons of rat visual cortex.
2019 Feb Nutrients Tryptophan-Tyrosine Dipeptide, the Core Sequence of β-Lactolin, Improves Memory by Modulating the Dopamine System.
2019 Neurotox Res Mechanism Underlying Organophosphate Paraoxon-Induced Kinetic Tremor.
2019 Int J Chron Obstruct Pulm... Real-life effectiveness of indacaterol-glycopyrronium after switching from tiotropium or salmeterolfluticasone therapy in patients with symptomatic COPD: the POWER study.
2018 eNeuro Cell Type- and Layer-Specific Muscarinic Potentiation of Excitatory Synaptic Drive onto Parvalbumin Neurons in Mouse Prefrontal Cortex.
2019 Biol Pharm Bull Assessment of Inhibitory Effects of Hypnotics on Acetylcholine-Induced Contractions in Isolated Rat Urinary Bladder Smooth Muscle.
2019 Drug Dev Ind Pharm Nicotine-like discriminative stimulus effects of acetylcholinesterase inhibitors and a muscarinic receptor agonist in Rhesus monkeys.
2019 Apr Neuroscience Augmentation of Endogenous Acetylcholine Uptake and Cholinergic Facilitation of Hippocampal Long-Term Potentiation by Acetylcholinesterase Inhibition.
2019 Neurobiol Dis Trihexyphenidyl rescues the deficit in dopamine neurotransmission in a mouse model of DYT1 dystonia.
2018 Pestic Biochem Physiol Pharmacology of central octopaminergic and muscarinic pathways in Drosophila melanogaster larvae: Assessing the target potential of GPCRs.
2019 Dtsch Med Wochenschr [Antidementia Drug Therapy of Alzheimer's Dementia: Status 2018 and Outlook].
2019 Jun Brain Res Commonalities and differences in extracellular levels of hippocampal acetylcholine and amino acid neurotransmitters during status epilepticus and sequent epileptogenesis in two rat models of temporal lobe epilepsy.
2019 Clin Exp Optom Alpha2 -adrenoceptor agonists inhibit form-deprivation myopia in the chick.
2019 Jan Pharmaceuticals (Basel) On the Absolute Stereochemistry of Tolterodine: A Circular Dichroism Study.
2018 Exp Lung Res CB2R agonist prevents nicotine induced lung fibrosis.
2019 Jan mSphere Repurposing Pilocarpine Hydrochloride for Treatment of Candida albicans Infections.
2019 Int J Chron Obstruct Pulm... A randomized trial to determine the impact of indacaterolglycopyrronium on nighttime oxygenation and symptoms in patients with moderate-to-severe COPD: the DuoSleep study.