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Recent literature: Protease inhibitor
Date Journal Article title
2020 Jan Curr Opin HIV AIDS Antiretroviral therapy in older people with HIV.
2019 Turk J Pediatr Netherton syndrome previously misdiagnosed as hyper IgE syndrome caused by a probable mutation in SPINK5 C.
2020 Jan J Nat Prod Microviridin 1777: A Toxic Chymotrypsin Inhibitor Discovered by a Metabologenomic Approach.
2020 Jan Microb Pathog Gga-miR-30d regulates infectious bronchitis virus infection by targeting USP47 in HD11 cells.
2020 Jan Int J Biol Macromol GdTI, the first thermostable trypsin inhibitor from Geoffroea decorticans seeds. A novel natural drug with potential application in biomedicine.
2020 Jan Int J Biol Macromol Structural and functional relationship of Cassia obtusifolia trypsin inhibitor to understand its digestive resistance against Pieris rapae.
2020 Jan Molecules Innovative Three-Step Microwave-Promoted Synthesis of iNi-Propargyltetrahydroquinoline and 1,2,3-Triazole Derivatives as a Potential Factor Xa (FXa) Inhibitors: Drug Design, Synthesis, and Biological Evaluation.
2020 Jan Br J Dermatol Successful treatment of Netherton syndrome with ustekinumab in a 15-year-old girl.
2020 Food Sci Biotechnol Protein purification from iArachis hypogaeai in one step: stability studies and anticarcinogenic analysis.
2020 Jan J Neurotrauma Penetrating Traumatic Brain Injury Triggers Subacute Dysregulation of Cathepsin B Protein Levels Independently of Cysteine Protease Activity in Brain and Cerebral Spinal Fluid.
2020 PLoS One HIV antiretroviral drugs, dolutegravir, maraviroc and ritonavir-boosted atazanavir use different pathways to affect inflammation, senescence and insulin sensitivity in human coronary endothelial cells.
2019 Front Physiol Transcription and Activity of Digestive Enzymes of iNezara viridulai Maintained on Different Plant Diets.
2020 Jan Cell Rep Structural Insights into the Unique Activation Mechanisms of a Non-classical Calpain and Its Disease-Causing Variants.
2020 Jan J Infect Dis Expanded Spectrum of Antiretroviral-Selected Mutations in Human Immunodeficiency Virus Type 2.
2020 Jan Int J Mol Sci The Subtilisin-Like Protease Bcser2 Affects the Sclerotial Formation, Conidiation and Virulence of iBotrytis cinereai.
2020 Jan Neurotox Res Neuroprotective Effects of Necrostatin-1 Against Oxidative Stress-Induced Cell Damage: an Involvement of Cathepsin D Inhibition.
2020 Jan Sci Rep Cathepsin B overexpression induces degradation of perilipin 1 to cause lipid metabolism dysfunction in adipocytes.
2020 Jan J Mol Endocrinol Soluble (pro)renin receptor increased by hypoxia maintains oxidative metabolism in trophoblasts.
2020 Jan Syst Biol Reprod Med Comparative proteomics reveals protective effect of resveratrol on a high-fat diet-induced damage to mice testis.
2020 Jan J Biol Chem Selective inhibition of matrix metalloproteinase 10 (MMP10) with a single-domain antibody.
2020 Jan Antiviral Res Identification and structural characterization of small molecule fragments targeting Zika virus NS2B-NS3 protease.
2020 Jan Biomolecules Serine Protease Inhibitors-New Molecules for Modification of Polymeric Biomaterials.
2020 Jan Int J Mol Sci Disabling the Protease DDI2 Attenuates the Transcriptional Activity of NRF1 and Potentiates Proteasome Inhibitor Cytotoxicity.
2020 Jan J Chem Inf Model Evaluating QMMM Free Energy Surfaces for Ranking Cysteine Protease Covalent Inhibitors.
2020 Jan Arthritis Rheumatol MALT1 protease activity is required for FcγR-induced arthritis but not FcγR-mediated platelet elimination in mice.
2020 Jan Biochem J A malaria parasite tilisin propeptide-like protein is a potent inhibitor of the egress protease SUB1.
2020 Jan Phys Chem Chem Phys Concerted hydrolysis mechanism of HIV-1 natural strate against types B and C-SA PR: insight through molecular dynamics and hybrid QMMM studies.
2020 Jan Sci Rep Hyaluronan presses enhanced cathepsin K expression via activation of NF-κB with mechanical stress loading in a human chondrocytic HCS-28 cells.
2020 Jan Plants (Basel) Assessment of Local and Systemic Changes in Plant Gene Expression and Aphid Responses during Potato Interactions with Arbuscular Mycorrhizal Fungi and Potato Aphids.
2020 Jan Pharmaceutics In Vitro, Ex Vivo and In Vivo Evaluation of Microcontainers for Oral Delivery of Insulin.
2020 Jan Toxins (Basel) Phosphate Limitation Increases Content of Protease Inhibitors in the Cyanobacterium iMicrocystis aeruginosai.
2020 Jan Biochimie Detection and in vitro studies of Cucurbita maxima phloem serpin-1 RNA-binding properties.
2020 Jan Antivir Ther Confirmation of the drug-drug interaction potential between cobicistat-boosted antiretroviral regimens and hormonal contraceptives.
2020 Jan AIDS Res Hum Retroviruses Diversity of Mexican HIV-1 Protease Sequences.
2020 Jan Int Forum Allergy Rhinol Significant polyomic and functional upregulation of the PAPP-AIGFBP-45IGF-1 axis in chronic rhinosinusitis with nasal polyps.
2020 PLoS One High failure rates of protease inhibitor-based antiretroviral treatment in rural Tanzania - A prospective cohort study.
2020 Jan ACS Chem Biol Integrative X-ray Structure and Molecular Modeling for the Rationalization of Procaspase-8 Inhibitor Potency and Selectivity.
2020 Feb Bioorg Med Chem Evaluation of an octahydroisochromene scaffold used as a novel SARS 3CL protease inhibitor.
2020 Jan Virus Genes Human immunodeficiency virus type-1 Tat protein induces secretory leukocyte protease inhibitor expression in African green monkey but not human cells.
2020 Jan Curr Genet SosA in Staphylococci: an addition to the paradigm of membrane-localized, SOS-induced cell division inhibition in bacteria.
2019 Jan Commun Biol Hepatocyte growth factor activator inhibitor-2 stabilizes Epcam and maintains epithelial organization in the mouse intestine.
2020 Jan Clin Cancer Res Proteomic analysis of CSF from patients with leptomeningeal melanoma metastases identifies signatures associated with disease progression and therapeutic resistance.
2020 Jan Eur J Med Chem Molecular design, synthesis, and biological evaluation of bisamide derivatives as cyclophilin A inhibitors for HCV treatment.
2020 PLoS One Pancreatic secretory trypsin inhibitor reduces multi-organ injury caused by gut ischemiareperfusion in mice.
2020 EClinicalMedicine Trend of HIV-1 drug resistance in China: A systematic review and meta-analysis of data accumulated over 17 years (2001-2017).
2019 Front Oncol Inhibition of Ubiquitin Specific Protease 1 Sensitizes Colorectal Cancer Cells to DNA-Damaging Chemotherapeutics.
2019 Front Pharmacol Six-Year Immunologic Recovery and Virological Suppression of HIV Patients on LPVr-Based Second-Line Antiretroviral Treatment: A Multi-Center Real-World Cohort Study in China.
2020 Jan FEBS J Highly drug-resistant HIV-1 protease reveals decreased intra-unit interactions due to clusters of mutations.
2020 Open Forum Infect Dis Clinical Outcomes Following the Use of Archived Proviral HIV-1 DNA Genotype to Guide Antiretroviral Therapy Adjustment.
2020 FASEB J Plasmin inhibition by bacterial serpin: Implications in gum disease.
2020 PLoS One Aberrant cervical innate immunity predicts onset of dysbiosis and sexually transmitted infections in women of reproductive age.
2019 Am J Cancer Res Prognostic and therapeutic relevance of cathepsin B in pediatric acute myeloid leukemia.
2019 Dec Theriogenology Recombinant SPINK3 improves ram sperm quality and in vitro fertility after cryopreservation.
2019 Vnitr Lek Current and future trends in the treatment of dyslipidemias.
2019 Dec Int J Mol Sci New Engineered-Botulinum Toxins Inhibit the Release of Pain-Related Mediators.
2019 Dec Molecules On the Reversible and Irreversible Inhibition of Rhodesain by Curcumin.
2020 Jan Dig Dis Sci Genetic Evaluation of Children with Idiopathic Recurrent Acute Pancreatitis.
2020 Jan Cell Mol Immunol A serine protease inhibitor induces type 1 regulatory T cells through IFN-γSTAT1 signaling.
2020 Jan J Biomol Struct Dyn Targeting metacaspase-3 from iPlasmodium falciparumi towards antimalarial therapy: A combined approach of iin-silicoi and iin-vitroi investigation.
2020 Jan Curr Drug Discov Technol The Influence of Hydrogen atoms on the Performance of Radial Distribution Function Based Descriptors in the Chemoinformatic Studies of HIV-1 Prote-ase Complexes with Inhibitors.
2019 Dec Biol Blood Marrow Transplant Immunopressive Drugs Alter α1-Antitrypsin Production in Hepatocytes: Implications for Epithelial Gap Repair.
2020 Bone Possible involvement of elastase in enhanced osteoclast differentiation by neutrophils through degradation of osteoprotegerin.
2020 Jan Clin Exp Metastasis Tissue inhibitor of matrix metalloproteinase-3 has both anti-metastatic and anti-tumourigenic properties.
2020 Jan Infection Pregnancy and neonatal outcomes in women with HIV-1 exposed to integrase inhibitors, protease inhibitors and non-nucleoside reverse transcriptase inhibitors: an observational study.
2019 Dec Sci Rep Nafamostat and sepimostat identified as novel neuroprotective agents via NR2B N-methyl-D-aspartate receptor antagonism using a rat retinal excitotoxicity model.
2020 Anticancer Res SAHA and EGCG Promote Apoptosis in Triple-negative Breast Cancer Cells, Possibly Through the Modulation of cIAP2.
2019 Dec Int J Mol Sci Haplotype in iSERPINA1i (AAT) Is Associated with Reduced Risk for COPD in a Mexican Mestizo Population.
2019 Dec Int J Biol Macromol Identification and characterization of a serine protease from Bacillus licheniformis W10: A potential antifungal agent.
2019 Biomed Res Int Tazarotene-Induced Gene 1 (TIG1) Interacts with Serine Protease Inhibitor Kazal-Type 2 (SPINK2) to Inhibit Cellular Invasion of Testicular Carcinoma Cells.
2020 Exp Ther Med Hydrogen sulfide modulates high glucose-induced NLRP3 inflammasome activation in 3T3-L1 adipocytes.
2020 Methods Mol Biol Evaluating MERS-CoV Entry Pathways.
2019 Dec J Biomol Struct Dyn Identification of a C2-symmetric diol based human immunodeficiency virus protease inhibitor targeting Zika virus NS2B-NS3 protease.
2019 Dec Sheng Li Xue Bao [Advanced glycated albumin induces macrophage pyroptosis via upregulating nucleotide-binding oligomerization domain-like receptor protein 3].
2019 Dec Cells Polyhexamethylene Guanidine Phosphate Damages Tight Junctions and the F-Actin Architecture by Activating Calpain-1 via the P2RX7Ca2+ Signaling Pathway.
2020 Feb Eur J Pharmacol Activated clotting factor X mediates mitochondrial alterations and inflammatory responses via protease-activated receptor signaling in alveolar epithelial cells.