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Recent literature: Protease inhibitor
Date Journal Article title
2019 Front Immunol SLPI Inhibits ATP-Mediated Maturation of IL-1β in Human Monocytic Leukocytes: A Novel Function of an Old Player.
2019 Apr Cell Death Dis Inhibition of HtrA2 alleviated dextran sulfate sodium (DSS)-induced colitis by preventing necroptosis of intestinal epithelial cells.
2019 Feb Dis Aquat Organ Testing plasma tilisin inhibitory activity as a selective marker for dermo resistance in eastern oysters.
2019 Apr J Am Chem Soc Discovery, X-ray Crystallography and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease.
2019 Apr Biochem Biophys Res Commun Vaspin prevents myocardial injury in rats model of diabetic cardiomyopathy by enhancing autophagy and inhibiting inflammation.
2019 Apr Genes (Basel) Molecular Characterization of a iDirofilaria immitisi Cysteine Protease Inhibitor (Cystatin) and Its Possible Role in Filarial Immune Evasion.
2019 Apr Cells Mast Cell Protease 7 Promotes Angiogenesis by Degradation of Integrin Subunits.
2019 May Zool Res Purification and characterization of a novel anti-coagulant from the leech Hirudinaria manillensis.
2019 Apr PLoS Negl Trop Dis A highly expressed intestinal cysteine protease of Ancylostoma ceylanicum protects vaccinated hamsters from hookworm infection.
2019 Apr Biophys J Allostery in Coagulation Factor VIIa Revealed by Ensemble Refinement of Crystallographic Structures.
2019 PLoS One Application of BisANS fluorescent dye for developing a novel protein assay.
2019 Oncol Rep Deubiquitinase USP9X regulates the invasion of prostate cancer cells by regulating the ERK pathway and mitochondrial dynamics.
2019 Apr Probiotics Antimicrob Pro... Assessment of Synthesis Machinery of Two Antimicrobial Peptides from Paenibacillus alvei NP75.
2019 Ther Adv Infect Dis Optimal treatment of HIV-associated neurocognitive disorders: myths and reality. A critical review.
2019 Front Immunol S-Nitrosylation of α1-Antitrypsin Triggers Macrophages Toward Inflammatory Phenotype and Enhances Intra-Cellular Bacteria Elimination.
2019 Aug Food Chem Localization of trypsin-like protease in postmortem tissue of white shrimp (Litopenaeus vannamei) and its effect in muscle softening.
2019 Int J STD AIDS Efficacy and safety of abacavirlamivudine with raltegravir in treatment-experienced and treatment-naïve patients with HIV-1 infection: an observational, retrospective, multi-centre study.
2019 Zhongguo Shi Yan Xue Ye X... [Effects of Ubiquitination on the Expression of BCL6 Protein,Cell Proliferation and Apoptosis in K562G01 Cells].
2019 Apr Fish Shellfish Immunol Two alpha-2 macroglobulin from Portunus trituberculatus involved in the prophenoloxidase system, phagocytosis and regulation of antimicrobial peptides.
2019 Apr J Med Chem Design, synthesis and pre-clinical characterization of selective Factor D inhibitors targeting the alternative complement pathway.
2019 Apr Mol Reprod Dev Prolyl oligopeptidase regulates progesterone secretion via the ERK signaling pathway in murine luteal cells.
2019 Apr Bioconjug Chem Acquired Removability of Aspartic Protease Inhibitors by Direct Biotinylation.
2019 Zhongguo Zhong Yao Za Zhi [Virtual screening study of cathepsin S natural inhibitor].
2019 Indian J Hematol Blood Tr... Low Protein Z Level: A Thrombophilic Risk Biomarker for Acute Coronary Syndrome.
2019 Medicine (Baltimore) Transurethral resection versus holmium laser enucleation of the prostate: A prospective randomized trial comparing perioperative thrombin generation and fibrinolysis.
2019 Apr J Acquir Immune Defic Syndr Switching to DoravirineLamivudineTenofovir Disoproxil Fumarate (DOR3TCTDF) Maintains HIV-1 Virologic Suppression Through 48 Weeks: Results of the DRIVE-SHIFT Trial.
2019 J Int AIDS Soc Pursuing use of optimal formulations for paediatric HIV epidemic control - a look at the use of LPVr oral pellets and oral granules.
2019 Apr J Infect Chemother A model-based comparative meta-analysis of the efficacy of dolutegravir-based and efavirenz-based regimens in HIV-infected patients.
2019 Apr Biochem Pharmacol Structure-based design and in vivo anti-arthritic activity evaluation of a potent dipeptidyl cyclopropyl nitrile inhibitor of cathepsin C.
2019 Apr Cell Death Differ Potent and selective caspase-2 inhibitor prevents MDM-2 cleavage in reversine-treated colon cancer cells.
2019 Apr Int J STD AIDS Ritonavir- or cobicistat-boosted antiretroviral therapy and direct oral anticoagulants: A case for apixaban.
2019 Apr Cancers (Basel) Ethanol-Mediated Stress Promotes Autophagic Survival and Aggressiveness of Colon Cancer Cells via Activation of Nrf2HO-1 Pathway.
2019 Apr J Allergy Clin Immunol Epithelium-derived Cystatin-SN enhances eosinophil activation and infiltration via interleukin-5 in chronic rhinosinusitis with nasal polyps.
2019 Apr Laryngoscope Aspergillus fumigatus induction of IL-33 expression in chronic rhinosinusitis is PAR2-dependent.
2019 PLoS One Inhibitors of signal peptide peptidase and tilisinkexin-isozyme 1 inhibit Ebola virus glycoprotein-driven cell entry by interfering with activity and cellular localization of endosomal cathepsins.
2019 PLoS One Structural characterization of PPTI, a kunitz-type protein from the venom of Pseudocerastes persicus.
2019 Apr ACS Chem Biol An Ancient Peptide Family Buried within Vicilin Precursors.
2019 Apr Andrologia Effects of dihydroartemisinin on HSP70 expression in human prostate cancer PC-3 cells.
2019 Apr J Innate Immun TGF-β1 Impairs Vitamin D-Induced and Constitutive Airway Epithelial Host Defense Mechanisms.
2019 Apr Pharmacoecon Open Cost-Effectiveness Analysis of LopinavirRitonavir Monotherapy Versus Standard Combination Antiretroviral Therapy in HIV-1 Infected Patients with Viral Suppression in France (ANRS 140 DREAM).
2019 PLoS One CCAAT-displacement proteincut homeobox transcription factor (CUX1) represses estrogen receptor-alpha (ER-α) in triple-negative breast cancer cells and can be antagonized by muscadine grape skin extract (MSKE).
2019 Apr Hepatology Evolutionary Pathways to Persistence of Highly Fit and Resistant Hepatitis C Virus Protease Inhibitor Escape Variants.
2019 Nagoya J Med Sci Partial Identification of Amyloid-β Degrading Activity in Human Serum.
2019 Apr Mol Cancer Ther Inhibition of Ubiquitin-specific protease 14 presses cell proliferation and synergizes with chemotherapeutic agents in neuroblastoma.
2019 Respir Med Sputum proteomic signature of gastro-oesophageal reflux in patients with severe asthma.
2019 Apr BMC Infect Dis Diversity of HIV-1 genotypes and high prevalence of pretreatment drug resistance in newly diagnosed HIV-infected patients in Shanghai, China.
2019 Apr Int J STD AIDS Drug interaction after ritonavir discontinuation: considerations for antiretroviral therapy changes in renal transplant recipients.
2019 Apr Mar Drugs Phomaketide A Inhibits Lymphangiogenesis in Human Lymphatic Endothelial Cells.
2019 PLoS One Stimulation of a protease targeting the LRIM1APL1C complex reveals specificity in complement-like pathway activation in Anopheles gambiae.
2019 Apr J Clin Invest USP9X deubiquitinates ALDH1A3 and maintains mesenchymal identity in glioblastoma stem cells.
2019 Apr Antivir Ther Drug susceptibility and replication capacity of a rare HIV-1 type C protease hinge region variant.
2019 Apr J Proteome Res Venom Composition in a Phenotypically Variable Pit Viper ( Trimeresurus insularis) across the Lesser Sunda Archipelago.
2019 Bioengineered Enhanced secretion of human α1-antitrypsin expressed with a novel glycosylation module in tobacco BY-2 cell culture.
2019 Apr J Am Heart Assoc Rivaroxaban, a Direct Factor Xa Inhibitor, Ameliorates Hypertensive Renal Damage Through Inhibition of the Inflammatory Response Mediated by Protease-Activated Receptor Pathway.
2019 J Food Sci Technol Impact of partial replacement of rice with other selected cereals on iidlii batter fermentation and iidlii characteristics.
2019 Apr CNS Neurosci Ther Thrombin disrupts vascular endothelial-cadherin and leads to hydrocephalus via protease-activated receptors-1 pathway.
2019 May J Chromatogr B Analyt Tec... Quantification of residual AEBSF-related impurities by reversed-phase liquid chromatography.
2019 Apr BMC Infect Dis Retention in care and virological failure among adult HIV+ patients on second-line ART in Rwanda: a national representative study.
2019 Apr J Cell Physiol The miR-27a-3pUSP25 axis participates in the pathogenesis of recurrent miscarriage by inhibiting trophoblast migration and invasion.
2019 Apr J Biol Chem Novel MASP-2 inhibitors developed iviai directed evolution of human TFPI1 are potent lectin pathway inhibitors.
2019 Open Forum Infect Dis Risk and Cost Associated With Drug-Drug Interactions Among Aging HIV Patients Receiving Combined Antiretroviral Therapy in France.
2019 Apr Int J Cancer Claudin7-dependent exosome-promoted reprogramming of non-metastasizing tumor cells.
2019 Apr Future Med Chem Recent progress on inhibitors of the type II transmembrane serine proteases, hepsin, matriptase and matriptase-2.
2019 Apr JCI Insight Site-1 protease-derived soluble (pro)renin receptor targets vasopressin receptor 2 to enhance urine concentrating capability.
2019 May Bioorg Med Chem Identification and design of novel small molecule inhibitors against MERS-CoV papain-like protease via high-throughput screening and molecular modeling.
2019 Apr J Med Chem Design, Synthesis, and Pharmacokinetic Evaluation of Phosphate and Amino Acid Ester Prodrugs for Improving the Oral Bioavailability of the HIV-1 Protease Inhibitor Atazanavir.
2016 Aug Pharmacoeconomic Review R...
2019 Mar J Struct Biol NMR structure of CmPI-II, a non- classical Kazal protease inhibitor: Understanding its conformational dynamics and tilisin A inhibition.
2019 Mar Peptides The discovery of shorter synthetic proteolytic peptides derived from Tob1 protein.
2019 Mar Anim Biotechnol Determination of genetic effects of SERPINA3 on important growth traits in beef cattle.
2019 Apr Proc Natl Acad Sci U S A Small-molecule factor B inhibitor for the treatment of complement-mediated diseases.
2019 Mar J Biol Chem Proteomic discovery of strates of the cardiovascular protease ADAMTS7.
2019 Case Rep Genet Identification and Mapping of a 2,009-bp DNA Deletion in iSERPING1i of a Hereditary Angioedema Patient.
2019 Mar Gut Serine proteases as luminal mediators of intestinal barrier dysfunction and symptom severity in IBS.
2019 Mar Am J Physiol Gastrointest... Intestinal serine protease inhibition increases FGF21 and improves metabolism in obese mice.