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Recent literature: Protease inhibitor
Date Journal Article title
2019 Feb Cancer Lett Proteasome inhibitor b-AP15 induces enhanced proteotoxicity by inhibiting cytoprotective aggresome formation.
2019 Feb Int J Colorectal Dis Prevalence of alpha-1-antitrypsin deficiency carriers in a population with and without colonic diverticula. A multicentre prospective case-control study: the ALADDIN study.
2019 Feb Br J Cancer HAI-2 as a novel inhibitor of plasmin represses lung cancer cell invasion and metastasis.
2019 Feb Exp Mol Pathol Proteomic characterization of early lung response to breast cancer metastasis in mice.
2019 Feb Phys Chem Chem Phys Molecular insight into chymotrypsin inhibitor 2 resisting proteolytic degradation.
2019 Feb J Virol HIV-1 type C with PYxE insertion has enhanced binding of Gag-p6 to host cell protein ALIX and increased replication fitness.
2019 Feb Curr HIV Res Real World Patient-Reported Outcomes In Hiv-Infected Adults Switching To Eviplera®, Because Of A Previous Intolerance To Cart. Pro-Str Stu.
2019 Feb Circulation Elevated Plasma Ceramides Are Associated With Antiretroviral Therapy Use and Progression of Carotid Artery Atherosclerosis in HIV Infection.
2019 Feb Lung Degradation of Lung Protective Angiotensin Converting Enzyme-2 by Meconium in Human Alveolar Epithelial Cells: A Potential Pathogenic Mechanism in Meconium Aspiration Syndrome.
2019 Feb Blood Adv Maintaining extraembryonic expression allows generation of mice with severe tissue factor pathway inhibitor deficiency.
2019 Feb Int Immunopharmacol Corrigendum to "Tryptase inhibitor APC 366 prevents hepatic fibrosis by inhibiting collagen synthesis induced by tryptaseprotease-activated receptor 2 interactions in hepatic stellate cells" [Int. Immunopharmacol. 20 (2014) 352-357].
2019 Feb J Antimicrob Chemother Stable prevalence of transmitted drug resistance mutations and increased circulation of non-B types in antiretroviral-naive chronically HIV-infected patients in 20152016 in France.
2019 Feb Plant Cell Physiol Avoiding Proteolysis During the Extraction and Purification of Active Plant Enzymes.
2019 Feb Bioinformatics Gag-protease coevolution shapes the outcome of Lopinavir-inclusive treatment regimens in chronically infected HIV-1 type C patients.
2019 Feb J Neurovirol Morphine counteracts the antiviral effect of antiretroviral drugs and causes upregulation of p62SQSTM1 and histone-modifying enzymes in HIV-infected astrocytes.
2019 Feb Antimicrob Agents Chemother Pharmacokinetic Interactions Between the HCV Inhibitors Elbasvir and Grazoprevir and HIV Protease Inhibitors Ritonavir, Atazanavir, Lopinavir, or Darunavir in Healthy Participants.
2019 Microbiol Res Specific regions of the SulA protein recognized and degraded by the ATP-dependent ClpYQ (HslUV) protease in Escherichia coli.
2019 Feb Plant Biotechnol J Activity-based proteomics reveals nine target proteases for the recombinant protein-stabilising inhibitor SlCYS8 in Nicotiana benthamiana.
2019 Endocr Pract CONSENSUS STATEMENT BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY ON THE COMPREHENSIVE TYPE 2 DIABETES MANAGEMENT ALGORITHM - 2019 EXECUTIVE SUMMARY.
2019 Feb AIDS Predictors of faster virological pression in early treated infants with perinatal HIV from Europe and Thailand.
2019 Feb Antivir Ther Provincial and national prevalence estimates of transmitted HIV-1 drug resistance in South Africa measured using two WHO-recommended methods.
2019 Feb Mol Reprod Dev N-linked mannose glycoconjugates on shrimp thrombospondin, pmTSP-II, and their involvement in the sperm acrosome reaction.
2019 Feb Oral Dis Role of mammary serine protease inhibitor on the inflammatory response in oral lichen planus.
2019 Feb Toxicol Appl Pharmacol The inhibitory effect of antiretroviral drugs on the L-carnitine uptake in human placenta.
2019 Feb J Am Chem Soc A Chemically-Disrupted Proximity System for Controlling Dynamic Cellular Processes.
2019 Feb Sci Rep Discovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1.
2019 Medicine (Baltimore) Comparative efficacy and safety of lipid-lowering agents in patients with hypercholesterolemia: A frequentist network meta-analysis.
2019 Feb J Agric Food Chem Inactivation of Soybean Bowman-Birk Inhibitor by Stevioside: Interaction Studies and Application to Soymilk.
2019 Feb J Clin Microbiol iIn vitroi Susceptibility of HCV Genotype 1 through 6 Clinical Isolates to the Pan-genotypic NS34A Inhibitor Voxilaprevir.
2019 J Enzyme Inhib Med Chem Development of a novel, high-affinity ssDNA trypsin inhibitor.
2019 Feb Clin J Gastroenterol Obstructive pancreatitis secondary to a pancreatic metastasis from lung cancer treated with nasopancreatic drainage.
2019 Feb Pharmacotherapy Effectiveness of Once-Daily Dolutegravir plus Boosted Darunavir as a Switch Strategy in Human Immunodeficiency Virus-Infected, Heavily Treated Patients.
2018 Aug Chronic Obstr Pulm Dis Intrapleural Gene Therapy for Alpha-1 Antitrypsin Deficiency-Related Lung Disease.
2019 Lancet HIV Incidence of switching to second-line antiretroviral therapy and associated factors in children with HIV: an international cohort collaboration.
2019 Feb J Org Chem Ring-Closing Metathesis on Commercial Scale: Synthesis of HCV Protease Inhibitor Simeprevir.
2019 Feb Hum Mol Genet Titin truncations lead to impaired cardiomyocyte autophagy and mitochondrial function in vivo.
2019 Jan Environ Entomol Mycorrhiza-Induced Resistance in Potato Involves Priming of Defense Responses Against Cabbage Looper (Noctuidae: Lepidoptera).
2019 Feb Curr HIV Res Molecular antiretroviral resistance markers of Human Immunodeficiency Virus-1 of CRF01_AE type in Bali, Indonesia.
2019 Chem Pharm Bull (Tokyo) New Method for Detecting the Suppressing Effect of Enzyme Activity by Aminopeptidase N Inhibitor.
2019 Biol Pharm Bull Synthesis and Biological Evaluation of 3,9-Dioxatetraasteranes as C2-Symmetric HIV-1 Protease Inhibitors and Docking Study.
2019 Gastroenterol Clin North Am Nonceliac Wheat Sensitivity: An Immune-Mediated Condition with Systemic Manifestations.
2019 Jan Chemosphere Effects of two protease inhibitors from Bauhinia bauhinoides with different specificity towards gut enzymes of Nasutitermes corniger and its survival.
2019 Jan Biol Blood Marrow Transplant Salivary changes before and after a hematopoietic stem cell transplantation: a systematic review.
2019 Jan Neurosci Lett Spinal macrophage migration inhibitory factor and high mobility group box 1 mediate persistent bladder pain.
2019 Jan Curr HIV Res Tobacco and Antiretrovirals Modulate Transporter, Metabolic Enzyme, and Antioxidant Enzyme Expression and Function in Polarized Macrophages.
2019 Jan J Viral Hepat MicroRNA-let-7c presses hepatitis C virus replication by targeting Bach1 for induction of heme oxygenase-1 expression.
2019 Jan J Cell Biochem microRNA-539 functions as a tumor pressor in papillary thyroid carcinoma via the transforming growth factor β1Smads signaling pathway by targeting secretory leukocyte protease inhibitor.
2019 Feb Invest New Drugs Lopinavir-NO, a nitric oxide-releasing HIV protease inhibitor, presses the growth of melanoma cells in vitro and in vivo.
2019 Jan Fish Shellfish Immunol iTRAQ analysis of liver immune-related proteins from darkbarbel catfish (Pelteobagrus vachelli) infected with Edwardsiella ictaluri.
2019 PLoS One Isolation and characterization of a tandem-repeated cysteine protease from the symbiotic dinoflagellate Symbiodinium sp. KB8.
2019 Jan J Clin Periodontol A Retrospective Analysis of Dental Implant Survival in HIV Patients.
2019 Jan J Biol Chem Disulfide engineering of human Kunitz-type serine protease inhibitors enhances proteolytic stability and target affinity toward mesotrypsin.
2019 Jan Chemistry Ultrafast Single-Scan 2D-NMR Spectroscopic Detection of a PHIP-Hyperpolarized Protease Inhibitor.
2019 Jan J Neurochem Venlafaxine stimulates PNN proteolysis and MMP-9 dependent enhancement of gamma power; relevance to antidepressant efficacy.
2018 Front Physiol Inhibitory Effect of Protease Inhibitors on Larval Midgut Protease Activities and the Performance of iPlutella xylostellai (Lepidoptera: Plutellidae).
2019 Jan J Biol Chem Murine astrotactins 1 and 2 have similar membrane topology and mature via endoproteolytic cleavage catalyzed by signal peptidase.
2019 J Enzyme Inhib Med Chem Virtual design of novel Plasmodium falciparum cysteine protease falcipain-2 hybrid lactone-chalcone and isatin-chalcone inhibitors probing the S2 active site pocket.
2019 Mar Life Sci Proteasome inhibition by MG-132 protects against deltamethrin-induced apoptosis in rat hippocampus.
2019 Nat Chem Biol An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient.
2019 Jan Cell Death Dis IFNβ enhances mesenchymal stromal (Stem) cells immunomodulatory function through STAT1-3 activation and mTOR-associated promotion of glucose metabolism.
2019 Jan J Leukoc Biol Tissue-type plasminogen activator neutralizes LPS but not protease-activated receptor-mediated inflammatory responses to plasmin.
2019 Jan Int J Biol Macromol Biophysical analysis of interaction between curcumin and alpha-2-macroglobulin.
2019 Jan Cancer Sci The deubiquitinase USP9X regulates the stability and function of E3 ubiquitin ligase RNF115 in breast cancer cells.
2019 HIV Med Low incidence of acute rejection within 6 months of kidney transplantation in HIV-infected recipients treated with raltegravir: the Agence Nationale de Recherche sur le Sida et les Hépatites Virales (ANRS) 153 TREVE trial.
2019 Jan Biol Pharm Bull USP34 regulated human pancreatic cancer cell survival via AKT and PKC pathways.
2019 Jan Fish Shellfish Immunol Endocrine-disrupting chemicals impair the innate immune prophenoloxidase system in the intertidal mud crab, Macrophthalmus japonicus.
2019 PLoS One Dissecting a novel allosteric mechanism of cruzain: A computer-aided approach.
2019 Jan Sci Rep Mammalian plasma fetuin-B is a selective inhibitor of ovastacin and meprin metalloproteinases.
2019 Jan Int J Mol Sci A Retrospective Analysis of the Cartilage Kunitz Protease Inhibitory Proteins Identifies These as Members of the Inter-α-Trypsin Inhibitor Superfamily with Potential Roles in the Protection of the Articulatory Surface.
2019 Jan Arch Biochem Biophys Human airway trypsin-like protease enhances interleukin-8 synthesis in bronchial epithelial cells by activating protease-activated receptor 2.
2019 PLoS One Thioguanine-based DENV-2 NS2BNS3 protease inhibitors: Virtual screening, synthesis, biological evaluation and molecular modelling.
2019 Jan Biochemistry Interaction of Human Drug-Metabolizing CYP3A4 with Small Inhibitory Molecules.
2019 Oncol Lett Expression of USP22 and the chromosomal passenger complex is an indicator of malignant progression in oral squamous cell carcinoma.
2019 Jan J Virol Validating Enterovirus D68-2Apro as an Antiviral Drug Target and the Discovery of Telaprevir as a Potent D68-2Apro Inhibitor.
2019 Jan Curr Drug Deliv Indinavir-Loaded Nanostructured Lipid Carriers to Brain Drug Delivery: Optimization, Characterization and Neuropharmacokinetic Evaluation.