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Recent literature: Nucleoside analog
Date Journal Article title
2020 Mar Nanomedicine A long-acting 3TC ProTide nanoformulation presses HBV replication in humanized mice.
2020 Mar J Biol Chem 5-Ethynyl-2'-deoxycytidine and 5-ethynyl-2'-deoxyuridine are differentially incorporated in cells infected with HSV-1, HCMV, and KSHV viruses.
2020 Mar Nucleosides Nucleotides N... The expression and activity of thymidine kinase 1 and deoxycytidine kinase are modulated by hydrogen peroxide and nucleoside analogs.
2020 Feb Drug Metab Pharmacokinet Synthesis and evaluation of nevirapine analogs to study the metabolic activation of nevirapine.
2020 Front Chem Probing of Nucleic Acid Structures, Dynamics, and Interactions With Environment-Sensitive Fluorescent Labels.
2020 Mar Angew Chem Int Ed Engl Repurposing antiviral drugs for orthogonal RNA-catalyzed labeling of RNA.
2020 Mar Nucleosides Nucleotides N... Synthesis and base-pairing properties of pyrazine nucleic acids.
2020 Feb J Pharm Biomed Anal Validation of an assay for quantifying ganciclovir in dried blood spots.
2020 Int J Nanomedicine Enhancing Antitumor Efficacy of Nucleoside Analog 5-Fluorodeoxyuridine on HER2-Overexpressing Breast Cancer by Affibody-Engineered DNA Nanoparticle.
2020 Feb mBio A Lassa Fever Live-Attenuated Vaccine Based on Codon Deoptimization of the Viral Glycoprotein Gene.
2020 Feb J Biol Chem The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus.
2020 Feb J Virol The pyrimidine analog FNC potently inhibits the replication of multiple enteroviruses.
2020 Einstein (Sao Paulo) Antiretroviral drug use by individuals living with HIVAIDS and compliance with the Clinical Protocol and Therapy Guidelines.
2020 Nat Protoc Superresolution imaging of chromatin fibers to visualize epigenetic information on replicative DNA.
2020 Jan Int J Mol Sci Adenosine Suppresses Cholangiocarcinoma Cell Growth and Invasion in Equilibrative Nucleoside Transporters-Dependent Pathway
2020 Jan J Med Virol Comparison of medication adherence and satisfaction between entecavir and tenofovir alafenamide therapy in chronic hepatitis B.
2020 Jan Purinergic Signal Prevention and rescue of cardiac dysfunction by methanocarba adenosine monophosphonate derivatives.
2020 Jan J Gastroenterol Hepatol Validation of hepatocellular carcinoma risk scores in Japanese chronic hepatitis B cohort receiving nucleot(s)ide analog.
2020 Cancer Chemother Pharmacol Repression of oncogenic cap-mediated translation by 4Ei-10 diminishes proliferation, enhances chemosensitivity and alters expression of malignancy-related proteins in mesothelioma.
2020 Antiviral Res Biosynthesis and half-life of MBX-2168-triphosphate in herpes virus-infected cells.
2019 Drug Discov Ther Inhibitions of human parainfluenza virus type 2 replication by ribavirin and mycophenolate mofetil are restored by guanosine and S-(4-nitrobenzyl)-6-thioinosine.
2020 Intern Med The Administration of Tenofovir Disoproxil Fumarate for Pregnant Japanese Women with Chronic Hepatitis B.
2020 Antiviral Res The discovery and development of filociclovir for the prevention and treatment of human cytomegalovirus-related disease.
2020 Curr Pharm Des Critical View on the Usage of Ribavirin in Already Existing Psychostimulant-Use Disorder.
2020 Antiviral Res Potent in vitro activity of β-D-4'-chloromethyl-2'-deoxy-2'-fluorocytidine against Nipah virus.
2020 Expert Rev Gastroenterol ... Trifluridinetipiracil for the treatment of metastatic gastric cancer.
2020 Hepatol Int Nucleoside analog monotherapy for prophylaxis in Hepatitis B liver transplant patients is safe and efficacious.
2020 Anticancer Res High Rate of Detection of Human ESPL1-HBV S Fusion Gene in Patients With HBV-related Liver Cancer: A Chinese Case-Control Study.
2019 Dec Int J Mol Sci Design, Synthesis and Molecular Modeling Study of Conjugates of ADP and Morpholino Nucleosides as A Novel Class of Inhibitors of PARP-1, PARP-2 and PARP-3.
2019 Dec Int J Mol Sci Acadesine Circumvents Azacitidine Resistance in Myelodysplastic Syndrome and Acute Myeloid Leukemia.
2020 Feb ACS Chem Biol Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases.
2020 Antiviral Res Abacavir induces the transcriptional activity of YY1 and other oncogenic transcription factors in gastric cancer cells.
2019 Pharmacol Res Perspect Role of equilibrative nucleoside transporter 1 (ENT1) in the disposition of cytarabine in mice.
2019 PLoS One Evaluation of the potential of a new ribavirin analog impairing the dissemination of ovarian cancer cells.
2020 Curr Opin HIV AIDS Mitochondria and ageing with HIV.
2020 Pharmacol Res FMS-like tyrosine kinase 3 (FLT3) modulates key enzymes of nucleotide metabolism implicated in cytarabine responsiveness in pediatric acute leukemia.
2020 Curr Opin HIV AIDS Long-acting implants to treat and prevent HIV infection.
2019 Oct J Vis Exp Measuring Proliferation of Vascular Smooth Muscle Cells Using Click Chemistry.
2020 Eur J Haematol An artificial nucleoside that simultaneously detects and combats drug resistance to doxorubicin.
2019 Nov J Comput Biol Learning Robust Multilabel Sample Specific Distances for Identifying HIV-1 Drug Resistance.
2019 Nov Nucleosides Nucleotides N... Synthesis and biochemical evaluation of iAminopropanolyli-Thymine itrii-Phosphate (iapi-TTP).
2019 Dec Mol Ther Oncolytics Targeting Histone Methyltransferase DOT1L by a Novel Psammaplin A Analog Inhibits Growth and Metastasis of Triple-Negative Breast Cancer.
2019 Nov Sci Rep Sangivamycin and its derivatives inhibit Haspin-Histone H3-survivin signaling and induce pancreatic cancer cell death.
2019 Nov Sci Rep Structural insights into mutagenicity of anticancer nucleoside analog cytarabine during replication by DNA polymerase η.
2020 Jan J Microbiol Biotechnol Inhibition of Herpes Simplex Viruses, Types 1 and 2, by Ginsenoside 20(S)-Rg3.
2020 Hepatol Res Early changes in tubular dysfunction markers and phosphorus metabolism regulators as a result of switching from entecavir to tenofovir alafenamide fumarate nucleoside analog therapy for chronic hepatitis B patients.
2020 Biochim Biophys Acta Gen ... Characterization of 5'-methylthioadenosineS-adenosylhomocysteine nucleosidases from Borrelia burgdorferi: Antibiotic targets for Lyme disease.
2020 Am J Hematol Phase III multisite trial of optimally dosed clofarabine and low-dose TBI for hematopoietic cell transplantation in acute myeloid leukemia.
2019 Nov J Biol Chem The Chd1 chromatin remodeler forms long-lived complexes with nucleosomes in the presence of ADP·BeF3 - and transition state analogs.
2019 Gastroenterology Nucleos(t)ide Analog Therapy of Chronic Hepatitis B and Liver Cancer Risk Reduction: Better Nucleotides than Nucleosides?
2019 Sep Genes (Basel) A Humanized Yeast Phenomic Model of Deoxycytidine Kinase to Predict Genetic Buffering of Nucleoside Analog Cytotoxicity.
2019 Sep Nucleosides Nucleotides N... Development of gapmer antisense oligonucleotide with deoxyribonucleic guanidine (DNG) modifications.
2019 Sep Nucleosides Nucleotides N... A highly constrained nucleic acid analog based on α-l-threosamine.
2019 Sep Nucleosides Nucleotides N... Synthesis and characterization of 4'-iCi-guanidinomethyl-2'-iOi-methyl-modified RNA oligomers.
2019 J Mass Spectrom CTP synthetase activity assay by liquid chromatography tandem mass spectrometry in the multiple reaction monitoring mode.
2019 Mol Med Rep Clofarabine‑phytochemical combination exposures in CML cells inhibit DNA methylation machinery, upregulate tumor pressor genes and promote caspase‑dependent apoptosis.
2019 Nov Cancer Res Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance.
2019 Aug Int J Mol Sci Mismatch Recognition by iSaccharomyces cerevisiaei Msh2-Msh6: Role of Structure and Dynamics.
2019 Sep Org Biomol Chem Compatibility of 5-ethynyl-2'F-ANA UTP with in vitro selection for the generation of base-modified, nuclease resistant aptamers.
2019 Oct J Biol Chem The DNA repair helicase RECQ1 has a checkpoint-dependent role in mediating DNA damage responses induced by gemcitabine.
2019 Cell Calcium The synthesis and characterization of a clickable-photoactive NAADP analog active in human cells.
2019 Eur J Endocrinol Associations between cutaneous fat density and systemic inflammation differ by HIV serostatus and are independent of fat quantity.
2019 J Pharmacol Exp Ther Novel Adenosine Analog, iNi6-(4-Hydroxybenzyl)-Adenosine, Dampens Alcohol Drinking and Seeking Behaviors.
2019 Aug Molecules Impact of the Position of the Chemically Modified 5-Furyl-2'-Deoxyuridine Nucleoside on the Thrombin DNA Aptamer-Protein Complex: Structural Insights into Aptamer Response from MD Simulations.
2019 RNA Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD from iPseudomonas aeruginosai.
2019 Int J Infect Dis Predictors of relapse after cessation of nucleos(t)ide analog treatment in HBeAg-negative chronic hepatitis B patients: A meta-analysis.
2019 Exp Ther Med Efficacy of methotrexate as anti-inflammatory and anti-proliferative drug in dermatology: Three case reports.
2019 Expert Rev Hematol Novel therapeutics in hairy cell leukemia.
2020 Hum Vaccin Immunother Safety and immunogenicity of the therapeutic vaccine TG1050 in chronic hepatitis B patients: a phase 1b placebo-controlled trial.
2019 Sep ACS Comb Sci Parallel Solution Phase Synthesis and Preliminary Biological Activity of a 5'-Substituted Cytidine Analog Library.
2019 Antiviral Res Antiviral candidates against the hepatitis E virus (HEV) and their combinations inhibit HEV growth in in vitro.
2019 Feb Am J Health Syst Pharm The safety and efficacy of trifluridine-tipiracil for metastatic colorectal cancer: A pharmacy perspective.
2019 Nat Struct Mol Biol Asymmetric histone inheritance via strand-specific incorporation and biased replication fork movement.
2020 Appl Biochem Biotechnol Viramidine-Loaded Galactosylated Nanoparticles Induce Hepatic Cancer Cell Apoptosis and Inhibit Angiogenesis.
2019 Dec J Acquir Immune Defic Syndr Brief Report: Relationship Between ABCC4 SNPs and Hepatitis B Virus Suppression During Tenofovir-Containing Antiretroviral Therapy in Patients With HIVHBV Coinfection.