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Recent literature: Anti-microtubule
Date Journal Article title
2019 Jun CPT Pharmacometrics Syst ... Time-to-Event Modeling of Peripheral Neuropathy - Platform Analysis of Eight vc-MMAE Antibody-Drug Conjugates (ADCs).
2019 Mediterr J Hematol Infect... Familial Mediterranean Fever: Assessing the Overall Clinical Impact and Formulating Treatment Plans.
2019 IET Nanobiotechnol HER-2 aptamer-targeted Ecoflex® nanoparticles loaded with docetaxel promote breast cancer cells apoptosis and anti-metastatic effect.
2019 May Colloids Surf B Biointerf... Loading Auristatin PE onto boron nitride nanotubes and their effects on the apoptosis of Hep G2 cells.
2019 Oncogene Resistance to anti-microtubule drug-induced cell death is determined by regulation of BimEL expression.
2018 Cancer Biol Med G2M inhibitors as pharmacotherapeutic opportunities for glioblastoma: the old, the new, and the future.
2019 Biochem Pharmacol BubR1 depletion delays apoptosis in the microtubule-depolymerized cells.
2018 Nov Anticancer Agents Med Chem Novel benzo[b]furans with anti-microtubule activity upregulate expression of apoptotic genes and arrest leukemia cells in G2M phase.
2018 Breast Three dimensional primary cultures for selecting human breast cancers that are sensitive to the anti-tumor activity of ipatasertib or taselisib in combination with anti-microtubule cytotoxic drugs.
2018 Nov Cancer Lett Novel CIL-102 derivatives as potential therapeutic agents for docetaxel-resistant prostate cancer.
2018 J Chemother Vinorelbine's anti-tumor actions may depend on the mitotic apoptosis, autophagy and inflammation: hypotheses with implications for chemo-immunotherapy of advanced cancers and pediatric gliomas.
2018 Mar Sci Rep Mechanism of action of the third generation benzopyrans and evaluation of their broad anti-cancer activity in vitro and in vivo.
2017 Breast Care (Basel) Adverse Events of Trastuzumab Emtansine (T-DM1) in the Treatment of HER2-Positive Breast Cancer Patients.
2018 Eur J Drug Metab Pharmaco... CYP Suppression in Human Hepatocytes by Monomethyl Auristatin E, the Payload in Brentuximab Vedotin (Adcetris®), is Associated with Microtubule Disruption.
2017 Sep Oncotarget Phosphatidylinositol 3-kinase (PI3Kα)AKT axis blockade with taselisib or ipatasertib enhances the efficacy of anti-microtubule drugs in human breast cancer cells.
2018 Artif Cells Nanomed Biote... Trastuzumab-modified DM1-loaded nanoparticles for HER2+ breast cancer treatment: an in vitro and in vivo study.
2017 Sep Oncotarget AG488 as a therapy against gliomas.
2017 Expert Opin Emerg Drugs An update on the developing mitotic inhibitors for the treatment of non-small cell carcinoma.
2017 Endocr Relat Cancer Fighting tubulin-targeting anticancer drug toxicity and resistance.
2017 PLoS One Imidazoquinoxaline anticancer derivatives and imiquimod interact with tubulin: Characterization of molecular microtubule inhibiting mechanisms in correlation with cytotoxicity.
2017 Cell Physiol Biochem Magnolol Inhibits the Growth of Non-Small Cell Lung Cancer via Inhibiting Microtubule Polymerization.
2017 Cancer Chemother Pharmacol Regulation of paclitaxel activity by microtubule-associated proteins in cancer chemotherapy.
2017 Biomaterials Sensitivity to antitubulin chemotherapeutics is potentiated by a photoactivable nanoliposome.
2017 Jul Oncotarget Structural recognition of tubulysin B derivatives by multidrug resistance efflux transporters in human cancer cells.
2017 Jun Int J Mol Sci Centrosomal Protein 70 Is a Mediator of Paclitaxel Sensitivity.
2017 Jul Bioorg Med Chem Click strategy using disodium salts of amino acids improves the water solubility of plinabulin and KPU-300.
2017 Apr Oncotarget Pygopus2 inhibits the efficacy of paclitaxel-induced apoptosis and induces multidrug resistance in human glioma cells.
2017 Mol Cancer Ther G-1 Inhibits Breast Cancer Cell Growth via Targeting Colchicine-Binding Site of Tubulin to Interfere with Microtubule Assembly.
2016 Indian J Cancer Eribulin in heavily pretreated metastatic breast cancer: A tertiary care center experience from India.
2017 Pharmacol Ther Anti-mitotic agents: Are they emerging molecules for cancer treatment?
2017 Curr Top Med Chem From Natural Products to Designer Drugs: Development and Molecular Mechanisms Action of Novel Anti-Microtubule Breast Cancer Therapeutics.
2016 Dec Molecules DeBouganin Diabody Fusion Protein Overcomes Drug Resistance to ADCs Comprised of Anti-Microtubule Agents.
2017 Pharmacol Ther Antibody-drug conjugate directed against the guanylyl cyclase antigen for the treatment of gastrointestinal malignancies.
2016 Infect Disord Drug Targets Combination Assays and Molecular Docking can Identify Binding sites of Anti-Microtubule Drugs on Plasmodium falciparum Tubulin.
2016 Nov Toxicol Appl Pharmacol A microtubule inhibitor, ABT-751, induces autophagy and delays apoptosis in Huh-7 cells.
2016 Nov Oncotarget The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti-microtubule drugs.
2016 Methods Mol Biol Anti-Microtubule Drugs.
2016 Ann Transl Med Predictive value of BRCA1 expression on the efficacy of chemotherapy based on anti-microtubule agents: a pooled analysis across different malignancies and agents.
2016 Apr Eur J Pharmacol Paclitaxel inhibits cell proliferation and collagen lattice contraction via TGF-β signaling pathway in human tenon's fibroblasts in vitro.
2015 PLoS One KPU-300, a Novel Benzophenone-Diketopiperazine-Type Anti-Microtubule Agent with a 2-Pyridyl Structure, Is a Potent Radiosensitizer That Synchronizes the Cell Cycle in Early M Phase.
2015 Dec BMC Med Response and survival of breast cancer intrinsic types following multi-agent neoadjuvant chemotherapy.
2016 Mod Rheumatol Antibodies to microtubule-associated protein-2 in the cerebrospinal fluid are a useful diagnostic biomarker for neuropsychiatric systemic lupus erythematosus.
2016 Oncol Rep The clinical significance of transforming acidic coiled-coil protein 3 expression in non-small cell lung cancer.
2015 Sichuan Da Xue Xue Bao Yi... [Effects of Minocycline on the Neuronal Plasticity in Rats after Focal Cerebral Ischemia Reperfusion Injury].
2015 Nov Oncotarget Septin cooperation with tubulin polyglutamylation contributes to cancer cell adaptation to taxanes.
2016 Artif Cells Nanomed Biote... Real-time monitoring of mesenchymal stem cell responses to biomaterial surfaces and to a model drug by using quartz crystal microbalance.
2015 Dec Cancer Lett The vascular disrupting activity of OXi8006 in endothelial cells and its phosphate prodrug OXi8007 in breast tumor xenografts.
2015 Nov Cancer Lett High affinity and covalent-binding microtubule stabilizing agents show activity in chemotherapy-resistant acute myeloid leukemia cells.
2015 Pediatr Res Assessment of long-term safety and efficacy of intranasal mesenchymal stem cell treatment for neonatal brain injury in the mouse.
2015 BioData Min Informative gene network for chemotherapy-induced peripheral neuropathy.
2015 J Neurooncol Colchicine derivative as a potential anti-glioma compound.
2015 Pediatr Blood Cancer Initial testing (stage 1) of the anti-microtubule agents cabazitaxel and docetaxel, by the pediatric preclinical testing program.
2015 Aug Chem Biol Interact Safranal as a novel anti-tubulin binding agent with potential use in cancer therapy: An in vitro study.
2015 Biochim Biophys Acta A novel anti-microtubule agent with carbazole and benzohydrazide structures presses tumor cell growth in vivo.
2015 Jun Int J Pharm The antitumor activity of PNA modified vinblastine cationic liposomes on Lewis lung tumor cells: In vitro and in vivo evaluation.
2015 Feb BMC Microbiol The tubulin cofactor A is involved in hyphal growth, conidiation and cold sensitivity in Fusarium asiaticum.
2015 PLoS One Collateral chemoresistance to anti-microtubule agents in a lung cancer cell line with acquired resistance to erlotinib.
2015 Iran Biomed J Evaluation of neurogenic potential of human umbilical cord mesenchymal cells; a time- and concentration-dependent manner.
2015 Apr Neuroscience Developmental changes in the flotillin-1 expression pattern of the rat visual cortex.
2015 Curr Cancer Drug Targets Targeting the spindle assembly checkpoint for breast cancer treatment.
2015 Biomed Pharmacother Deacetyl-mycoepoxydiene, isolated from plant endophytic fungi Phomosis sp. demonstrates anti-microtubule activity in MCF-7 cells.
2014 Onco Targets Ther Microtubule inhibitor-based antibody-drug conjugates for cancer therapy.
2014 Aug Zhongguo Fei Ai Za Zhi [Down-regulated βIII-tubulin expression can reverse paclitaxel resistance in A549taxol cells lines].
2014 PLoS One Characterization of a putative spindle assembly checkpoint kinase Mps1, suggests its involvement in cell division, morphogenesis and oxidative stress tolerance in Candida albicans.
2014 Open Biol Optimization of the analogue-sensitive Cdc2Cdk1 mutant by in vivo selection eliminates physiological limitations to its use in cell cycle analysis.
2014 Sep Toxicol Lett Evaluation of 2',4'-dihydroxy-3,4,5-trimethoxychalcone as antimitotic agent that induces mitotic catastrophe in MCF-7 breast cancer cells.
2014 Mar Breast Cancer Res Trastuzumab emtansine: mechanisms of action and drug resistance.
2014 Int J Med Sci A cell-based pharmacokinetics assay for evaluating tubulin-binding drugs.
2014 Br J Haematol Leukaemic cells from chronic lymphocytic leukaemia patients undergo apoptosis following microtubule depolymerization and Lyn inhibition by nocodazole.
2014 Onco Targets Ther Nab-paclitaxel: potential for the treatment of advanced pancreatic cancer.
2014 Hematol Oncol Brentuximab vedotin followed by allogeneic transplantation as salvage regimen in patients with relapsed andor refractory Hodgkin's lymphoma.
2014 Cell Cycle GSI promotes vincristine-induced apoptosis by enhancing multi-polar spindle formation.
2013 Dec Bioorg Med Chem Lett Structure-activity relationship studies of thalidomide analogs with a taxol-like mode of action.
2013 Anticancer Res AG11, a novel dichloroflavanone derivative with anti-mitotic activity towards human bladder cancer cells.
2013 Nov Chemistry Mirror-image organometallic osmium arene iminopyridine halido complexes exhibit similar potent anticancer activity.