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Recent literature: Signal transduction inhibitor
Date Journal Article title
2020 Feb BMC Genomics Transcriptomic analysis of the testicular fusion in Spodoptera litura.
2020 Feb Biochem Biophys Res Commun DNA methylation status influences insulin-induced glucose transport in 3T3-L1 adipocytes by mediating p53 expression.
2020 Feb Transl Psychiatry Rivastigmine modifies the α-secretase pathway and potentially early Alzheimer's disease.
2020 Feb Int J Mol Sci Dynamic Changes in pStat3 are Involved in Meiotic Spindle Assembly in Mouse Oocytes.
2020 Am J Chin Med Glycyrrhizic Acid Modulates Apoptosis through ExtrinsicIntrinsic Pathways and Inhibits Protein Kinase B- and Extracellular Signal-Regulated Kinase-Mediated Metastatic Potential in Hepatocellular Carcinoma iIn Vitroi and iIn Vivoi.
2020 Feb Life (Basel) Coupling of Cell Division and Differentiation in iArabidopsis thalianai Cultured Cells with Interaction of Ethylene and ABA Signaling Pathways.
2020 Feb Cell Death Dis Metformin reduces HGF-induced resistance to alectinib via the inhibition of Gab1.
2019 Front Immunol Cullin-5 Adaptor SPSB1 Controls NF-κB Activation Downstream of Multiple Signaling Pathways.
2020 Feb J Proteome Res KinobeadLC-MS Phosphokinome Profiling Enables Rapid Analyses of Kinase-Dependent Cell Signaling Networks.
2020 Jan Redox Biol A stress response p38 MAP kinase inhibitor SB202190 promoted TFEBTFE3-dependent autophagy and lysosomal biogenesis independent of p38.
2020 Adv Exp Med Biol Recent Advances in Understanding Mechanisms of TGF Beta Signaling and Its Role in Glioma Pathogenesis.
2020 Adv Exp Med Biol Cytoskeleton and Nucleotide Signaling in Glioma C6 Cells.
2020 Feb Sci Rep Establishment of Structure-Function Relationship of Tissue Inhibitor of Metalloproteinase-1 for Its Interaction with CD63: Implication for Cancer Therapy.
2020 Feb Cells Impairment of Membrane Lipid Homeostasis by Bichalcone Analog TSWU-BR4 Attenuates Function of GRP78 in Regulation of the Oxidative Balance and Invasion of Cancer Cells.
2020 Adv Exp Med Biol Translational Landscape of mTOR Signaling in Integrating Cues Between Cancer and Tumor Microenvironment.
2020 Feb J Cancer Res Clin Oncol The PI3K pathway impacts stem gene expression in a set of glioblastoma cell lines.
2020 Feb JCI Insight Extracellular CIRP induces macrophage endotoxin tolerance through IL-6R-mediated STAT3 activation.
2020 Zhongguo Shi Yan Xue Ye X... [Dihydroartemisinin Induces AML cell Apoptosis by Inhibition of PTENAKT pathway].
2020 Feb FEBS Open Bio The PI3KmTOR dual inhibitor NVP-BEZ235 stimulates mutant p53 degradation to exhibit anti-tumor effect on triple-negative breast cancer cells.
2020 Feb J Biol Chem A specific amino acid context in EGFR and HER2 phosphorylation sites enables selective binding to the active site of Src homology phosphatase 2 (SHP2).
2020 Reproduction Adiponectin stimulates glucose uptake in mouse blastocysts and embryonic carcinoma cells.
2020 Braz Oral Res Smad15 signal transduction regulates the ameloblastic differentiation of induced pluripotent stem cells.
2020 Feb BMC Plant Biol Transcriptome analysis reveals insight into molecular hydrogen-induced cadmium tolerance in alfalfa: the prominent role of sulfur and (homo)glutathione metabolism.
2020 Feb Curr Pharm Des Research advances in the molecular functions and relevant diseases of TAOKs, novel STE20 kinase family members.
2020 Jan Int J Mol Sci Myoblast Migration and Directional Persistence Affected by Syndecan-4-Mediated Tiam-1 Expression and Distribution.
2020 Jan J Nutr Biochem Emodin and emodin-rich rhubarb inhibits histone deacetylase (HDAC) activity and cardiac myocyte hypertrophy.
2020 Plant Sci Overexpression of PtDefensin enhances resistance to Septotis populiperda in transgenic poplar.
2020 J Clin Biochem Nutr Induction of a 5-lipoxygenase product by daidzein is involved in the regulation of influenza virus replication.
2020 J Enzyme Inhib Med Chem Selective inhibitors for JNK signalling: a potential targeted therapy in cancer.
2020 Jan Cell Commun Signal FGFR3 signaling and function in triple negative breast cancer.
2020 Jan J Invest Surg TSG-6 Inhibits the Growth of Keloid Fibroblasts Via Mediating the TGF-β1Smad Signaling Pathway.
2019 Aug Bioorg Chem Design, synthesis and evaluation of wound healing activity for β-sitosterols derivatives as potent Na+K+-ATPase inhibitors.
2020 Mar Life Sci Novel ADAM-17 inhibitor ZLDI-8 inhibits the metastasis of hepatocellular carcinoma by reversing epithelial-mesenchymal transition in vitro and in vivo.
2020 Jan J Invest Dermatol Molecular and Cellular Responses to the TYK2JAK1 Inhibitor, PF 06700841, Reveal Reduction of Skin Inflammation in Plaque Psoriasis: TYK2JAK1 inhibitor in plaque psoriasis.
2020 PLoS Genet The Arabidopsis receptor kinase STRUBBELIG regulates the response to cellulose deficiency.
2020 Feb J Agric Food Chem Procyanidin B2 Promotes Skeletal Slow-Twitch Myofiber Gene Expression through the AMPK Signaling Pathway in C2C12 Myotubes.
2020 Jan Int Endod J Effects of transforming growth factor-β1 on plasminogen activation in stem cells from the apical papilla: role of activating receptor-like kinase 5Smad2 and mitogen-activated protein kinase kinase (MEK)extracellular signal-regulated kinase (ERK) signalling.
2020 Mar Life Sci Decreased secretion of tumor necrosis factor-α attenuates macrophages-induced insulin resistance in skeletal muscle.
2020 Mar Life Sci MiR-346-5p promotes colorectal cancer cell proliferation in vitro and in vivo by targeting FBXL2 and activating the β-catenin signaling pathway.
2019 Oct Open Access Maced J Med Sci Experimental, Clinical and Morphological Analysis of H-Ras Oncoproteins for Locally Advanced Breast Cancer.
2020 Jan J Sci Food Agric Transcriptome analysis reveals delaying of the ripening and cell-wall degradation of kiwifruit by hydrogen sulfide.
2020 Jan N Engl J Med JAK Inhibitor Therapy in a Child with Inherited USP18 Deficiency.
2020 Apr Toxicol Lett 1,2-Dichloroethane induces cerebellum granular cell apoptosis via mitochondrial pathway in vitro and in vivo.
2020 Jan Respir Res ZDHXB-101 (3',5-Diallyl-2, 4'-dihydroxy-[1,1'-biphen-yl]-3,5'-dicarbaldehyde) protects against airway remodeling and hyperresponsiveness via inhibiting both the activation of the mitogen-activated protein kinase and the signal transducer and activator of transcription-3 signaling pathways.
2020 Jan J Cutan Pathol Lichen planus related to transforming growth factor beta inhibitor in a patient with metastatic chondrosarcoma: a case report.
2020 Jan Lab Invest TGFβ1-Smad canonical and -Erk noncanonical pathways participate in interleukin-17-induced epithelial-mesenchymal transition in Sjögren's syndrome.
2020 PLoS One Identification and characterization of miRNAs involved in cold acclimation of zebrafish ZF4 cells.
2019 Front Endocrinol (Lausanne) CRF1 Receptor Signaling via the ERK12-MAP and Akt Kinase Cascades: Roles of Src, EGF Receptor, and PI3-Kinase Mechanisms.
2019 Front Cell Neurosci Store-Operated Calcium Channels Are Involved in Spontaneous Slow Calcium Oscillations in Striatal Neurons.
2020 Jan Inflammation Rho kinase Blockade Ameliorates DSS-Induced Ulcerative Colitis in Mice Through Dual Inhibition of the NF-κB and IL-6STAT3 Pathways.
2020 Korean J Physiol Pharmacol Ezrin-radixin-moesin proteins are regulated by Akt-GSK3β signaling in the rat nucleus accumbens core.
2019 J Exp Pharmacol Inhibition of iTrypanosoma evansii Protein-Tyrosine Phosphatase by Myristic Acid Analogues Isolated from iKhaya senegalensisi and Tamarindus iindicai.
2020 Nihon Yakurigaku Zasshi [The effect of PHD inhibitor on tumor microenvironment and tumor immune response].
2020 Biomed Pharmacother Inhibition of osteoclast activity by complement regulation with DF3016A, a novel small-molecular-weight C5aR inhibitor.
2019 Dec Biochem Biophys Res Commun Subquinocin, a small molecule inhibitor of CYLD and USP-family deubiquitinating enzymes, promotes NF-κB signaling.
2020 Jan J Physiol Biochem The isoflavone genistein enhances osteoblastogenesis: signaling pathways involved.
2019 Xi Bao Yu Fen Zi Mian Yi ... [oxLDLβ2GPIanti-β2GPI antibody complex inhibits autophagy in RAW264.7 cells through the activation of AKT pathway].
2020 Anticancer Res COUP-TFII Knock-down Promotes Proliferation and Invasion in Colorectal Cancer Cells iviai Activation of Akt Pathway and Up-regulation of FOXC1.
2020 Anticancer Res Taxotere Induces Dephosphorylation of MET in Patient-derived Tumor Models.
2020 Mar Exp Cell Res Tenovin-6 induces the SIRT-independent cell growth pression and blocks autophagy flux in canine hemangiosarcoma cell lines.
2019 Oxid Med Cell Longev Antioxidant and the Dwarfing Candidate Gene of "Nantongxiaofangshi" (iDiospyros kakii Thunb.).
2019 Mediators Inflamm Tumor Necrosis Factor (TNF) Receptor Expression Determines Keratinocyte Fate upon Stimulation with TNF-Like Weak Inducer of Apoptosis.
2020 Mar Life Sci Effect of endoplasmic reticulum stress-mediated excessive autophagy on apoptosis and formation of kidney stones.
2019 Dec Oral Dis Molecular mechanisms for short root anomaly.
2019 Dec Sci Rep Specific role of N-methyl-D-aspartate (NMDA) receptor in elastin-derived VGVAPG peptide-dependent calcium homeostasis in mouse cortical astrocytes in vitro.
2020 Feb Life Sci MiR-424 overexpression protects alveolar epithelial cells from LPS-induced apoptosis and inflammation by targeting FGF2 via the NF-κB pathway.
2020 Feb Life Sci Dihydroartemisinin inhibits endothelial cell tube formation by pression of the STAT3 signaling pathway.
2020 Jan Biomol Ther (Seoul) Function of NADPH Oxidases in Diabetic Nephropathy and Development of Nox Inhibitors.
2020 Biomed Pharmacother Cyclooxygenase activity in bradykinin-induced dermal extravasation. A study in mice and humans.
2020 Feb Life Sci MicroRNA-31184 is involved in transforming growth factor-β-induced apoptosis in A549 human alveolar adenocarcinoma cells.
2020 Feb Life Sci Periostin reverses high glucose-inhibited osteogenesis of periodontal ligament stem cells via AKT pathway.
2019 Biochemistry (Mosc) Akt1-Mediated Phosphorylation of RBP-Jk Controls Notch1 Signaling.
2019 Dec Lipids Inhibition of Calcineurin and Glycogen Synthase Kinase-3β by Ricinoleic Acid Derived from Castor Oil.
2020 Hypertension Stretch-Induced Increases in Intracellular Ca Stimulate Thick Ascending Limb O2- Production and Are Enhanced in Dahl Salt-Sensitive Rats.
2019 Nov Med Sci Monit C-Terminus of E1A Binding Protein 1 Stimulates Malignant Phenotype in Human Hepatocellular Carcinoma.