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Recent literature: D2 receptor antagonist
Date Journal Article title
2019 Aug Behav Neurosci Involvement of D1- and D2-like dopamine receptors within the rat nucleus accumbens in the maintenance of morphine rewarding properties in the rats.
2019 Aug Bioorg Med Chem Lett Rasagiline derivatives combined with histamine H3 receptor properties.
2019 Aug Prog Neurobiol Role of homeostatic feedback mechanisms in modulating methylphenidate actions on phasic dopamine signaling in the striatum of awake behaving rats.
2019 Aug Naunyn Schmiedebergs Arch... Dopamine D1 receptor antagonist reduces stimulant-induced conditioned place preferences and dopamine receptor ersensitivity.
2019 Ann Clin Psychiatry Ecopipam as a pharmacologic treatment of stuttering.
2019 Jul Eur J Neurosci The priming effect of food persists following blockade of dopamine receptors.
2019 Sep Eur J Pharmacol Dopamine D1 and D2 receptors mediate neuropeptide S-induced antinociception in the mouse formalin test.
2019 Psychopharmacology (Berl) Computational modelling reveals contrasting effects on reinforcement learning and cognitive flexibility in stimulant use disorder and obsessive-compulsive disorder: remediating effects of dopaminergic D23 receptor agents.
2019 Jul Neurosci Res Methylenedioxypyrovalerone (MDPV) impairs working memory and alters patterns of dopamine signaling in mesocorticolimbic strates.
2019 Jul Neuropharmacology AMP-activated protein kinase slows D2 dopamine autoreceptor desensitization in stantia nigra neurons.
2019 Jul FEBS Open Bio Dopamine receptor D2 activation presses the radiosensitizing effect of aripiprazole via activation of AMPK.
2019 Jul J Comp Neurol Dopaminergic modulation of olfactory-evoked motor output in sea lampreys (Petromyzon marinus L.).
2019 Jul J Pharmacol Exp Ther Revisiting the pharmacodynamics uroselectivity of Alpha1-Adrenergic Receptor Antagonists.
2019 Jul Psychopharmacology (Berl) Role of dopamine D1-like and D2-like receptors in the activation of ingestive behaviour in thirsty rats licking for water.
2019 Jul Allergy Evidence for the induction of Th2 inflammation by group 2 innate lymphoid cells in response to prostaglandin D2 and cysteinyl leukotrienes in allergic rhinitis.
2019 Mol Pharmacol Innovative Bioluminescence Resonance Energy Transfer Assay Reveals Differential Agonist-Induced D2 Receptor Intracellular Trafficking and Arrestin-3 Recruitment.
2019 Neuropharmacology Ketamine-induced regulation of TrkB-GSK3β signaling is accompanied by slow EEG oscillations and sedation but is independent of hydroxynorketamine metabolites.
2019 Jun Int J Mol Sci A Free-Operant Reward-Tracking Paradigm to Study Neural Mechanisms and Neurochemical Modulation of Adaptive Behavior in Rats.
2019 Neuropharmacology D2 receptor-mediated miRNA-143 expression is associated with the effects of antipsychotic drugs on phencyclidine-induced schizophrenia-related locomotor hyperactivity and with Neuregulin-1 expression in mice.
2019 Jun Eur J Med Chem 2-Aminoimidazole-based antagonists of the 5-HT6 receptor - A new concept in aminergic GPCR ligand design.
2019 Sep Eur J Med Chem Synthesis and computer-aided SAR studies for derivatives of phenoxyalkyl-1,3,5-triazine as the new potent ligands for serotonin receptors 5-HT6.
2019 Psychoneuroendocrinology Allopregnanolone is required for prepulse inhibition deficits induced by D1 dopamine receptor activation.
2019 J Recept Signal Transduct... Dopamine-induced functional activation of Gαq mediated by dopamine D1-like receptor in rat cerebral cortical membranes.
2019 Front Pharmacol Evaluation of Functional Selectivity of Haloperidol, Clozapine, and LASSBio-579, an Experimental Compound With Antipsychotic-Like Actions in Rodents, at G Protein and Arrestin Signaling Downstream of the Dopamine D2 Receptor.
2019 Pulm Pharmacol Ther Fevipiprant has a low risk of influencing co-medication pharmacokinetics: Impact on simvastatin and rosuvastatin in different SLCO1B1 genotypes.
2019 Neurogastroenterol Motil Regulation of stress-induced gastric ulcers via central oxytocin and a potential mechanism through the VTA-NAc dopamine pathway.
2019 Jun Psychopharmacology (Berl) Dopamine D1 and D2 receptors mediate analgesic and hypnotic effects of l-tetrahydropalmatine in a mouse neuropathic pain model.
2019 Jun Acta Pharmacol Sin Preclinical PKPD model for the combinatorial use of dexamethasone and sulpiride in the treatment of breast cancer.
2019 Jun J Psychopharmacol Regulation of adenosine A2A receptor gene expression in a model of binge eating in the amygdaloid complex of female rats.
2019 May Nat Prod Res Study on antidepressant-like effect of protoilludane sesquiterpenoid aromatic esters from iArmillaria Melleai.
2019 Biochem Pharmacol A structure-function approach identifies L-PGDS as a mediator responsible for glucocorticoid-induced leptin expression in adipocytes.
2019 Sep Neuropharmacology Optogenetic control of alcohol-seeking behavior via the dorsomedial striatal circuit.
2019 Case Rep Psychiatry Accidental Overdose of Paliperidone Palmitate.
2019 CNS Neurosci Ther Procognitive impact of ciproxifan (a histaminergic H3 receptor antagonist) on contextual memory retrieval after acute stress.
2019 Iran J Pharm Res The Involvement of Intra-Hippocampal Dopamine Receptors in the Conditioned Place Preference Induced By Orexin Administration into the Rat Ventral Tegmental Area.
2019 Brain Struct Funct Dissociable effects of dopamine D1 and D2 receptors on compulsive ingestion and pivoting movements elicited by disinhibiting the ventral pallidum.
2019 J Psychopharmacol Role of the galanin N-terminal fragment (1-15) in anhedonia: Involvement of the dopaminergic mesolimbic system.
2019 Psychopharmacology (Berl) Modulation by chronic antipsychotic administration of PKA- and GSK3β-mediated pathways and the NMDA receptor in rat ventral midbrain.
2019 Mar Arch Iran Med The Involvement of D1 and D2 Dopamine Receptors in the Restoration Effect of Left Frontal Anodal, but not Cathodal, tDCS on Streptozocin-Induced Amnesia.
2019 Front Neurosci Voluntary Wheel Running Reverses Deficits in Social Behavior Induced by Chronic Social Defeat Stress in Mice: Involvement of the Dopamine System.
2019 Apr CNS Spectr The role of dopamine D3 receptors in the mechanism of action of cariprazine.
2019 J Neurochem Differential regulation of phasic dopamine release in the forebrain by the VTA noradrenergic receptor signaling.
2019 Neurochem Int Blonanserin ameliorates social deficit through dopamine-D3 receptor antagonism in mice administered phencyclidine as an animal model of schizophrenia.
2019 Apr Int J Mol Sci Distinct Dopamine D₂ Receptor Antagonists Differentially Impact D₂ Receptor Oligomerization.
2019 May Bioorg Med Chem Chemical synthesis, microbial transformation and biological evaluation of tetrahydroprotoberberines as dopamine D1D2 receptor ligands.
2019 Front Neurosci GPR139 and Dopamine D2 Receptor Co-express in the Same Cells of the Brain and May Functionally Interact.
2019 Curr Pharm Des Therapeutic Effect of Novel Antidepressant Drugs Acting at Specific Receptors of Neurotransmitters and Neuropeptides.
2019 Cogn Neurodyn L-menthol exhibits antidepressive-like effects mediated by the modification of 5-HTergic, GABAergic and DAergic systems.
2019 Apr J Neurosurg Pediatr First clinical experience with DRD23 antagonist ONC201 in H3 K27M-mutant pediatric diffuse intrinsic pontine glioma: a case report.
2019 Jul Eur J Pharmacol A CRTH2 antagonist, CT-133, presses NF-κB signalling to relieve lipopolysaccharide-induced acute lung injury.
2019 Neurourol Urodyn Dopaminergic urethral closure mechanisms in a rat model of Parkinson's disease.
2019 Mar BMJ Case Rep Can typical and atypical antipsychotics show differential effectiveness in treating paranoia and hallucinations in schizophrenia?
2019 Jun Eur J Pharmacol Dehydroepiandrosterone sulfate improves visceral sensation and gut barrier in a rat model of irritable bowel syndrome.
2019 May Neuroscience Presynaptic control of [3H]-glutamate release by dopamine receptor types in the rat stantia nigra. Central role of D1 and D3 receptors.
2019 May Chem Biol Interact Methiopropamine, a methamphetamine analogue, produces neurotoxicity via dopamine receptors.
2019 Psychopharmacology (Berl) Effects of intrastriatal dopamine D1 or D2 antagonists on methamphetamine-induced egocentric and allocentric learning and memory deficits in Sprague-Dawley rats.
2019 J Smooth Muscle Res Sustained exposure to prostaglandin D2 augments the contraction induced by acetylcholine via a DP1 receptor-mediated activation of p38 in bronchial smooth muscle of naive mice.
2019 Mar J Biomol Struct Dyn Design of novel dopamine D2 and serotonin 5-HT2A receptors dual antagonists toward schizophrenia: An integrated study with QSAR, molecular docking, virtual screening and molecular dynamics simulations.
2019 Front Pharmacol Participation of Dopamine D1 and D2 Receptors in the Rapid-Onset Behavioral Sensitization to Modafinil.
2019 Eur Neuropsychopharmacol Atypical but not typical antipsychotic drugs ameliorate phencyclidine-induced emotional memory impairments in mice.
2019 Pharmacol Biochem Behav 5-HT2A receptors modulate dopamine D2-mediated maternal effects.
2019 Br Poult Sci Interaction of the dopaminergic and NociceptinOrphanin FQ on central feed intake regulation in chicken.
2019 Apr J Med Chem Dopamine D4 Receptor-Selective Compounds Reveal Structure-Activity Relationships that Engender Agonist Efficacy.
2019 Neuropsychopharmacology Selective D2 and D3 receptor antagonists oppositely modulate cocaine responses in mice via distinct postsynaptic mechanisms in nucleus accumbens.
2019 Int Arch Allergy Immunol Effects of an Oral CRTh2 Antagonist (AZD1981) on Eosinophil Activity and Symptoms in Chronic Spontaneous Urticaria.
2019 J Pharmacol Exp Ther Inhibition of Methamphetamine Self-Administration and Reinstatement by Central Blockade of Angiotensin II Receptor in Rats.
2019 CNS Spectr 30 Lumateperone (ITI-007) for the Treatment of Schizophrenia: Overview of Placebo-Controlled Clinical Trials and an Open-label Safety Switching Study.
2019 J Comput Aided Mol Des Significantly different effects of tetrahydroberberrubine enantiomers on dopamine D1D2 receptors revealed by experimental study and integrated in silico simulation.
2019 eNeuro An Adenosine A2A Receptor Antagonist Improves Multiple Symptoms of Repeated Quinpirole-Induced Psychosis.
2019 J Allergy Clin Immunol Fevipiprant, a selective prostaglandin D2 receptor 2 antagonist, inhibits human group 2 innate lymphoid cell aggregation and function.
2019 Pharmacol Rev Modulating Dopamine Signaling and Behavior with Chemogenetics: Concepts, Progress, and Challenges.
2019 Apr Bioorg Med Chem Lett Biotinylated-spiperone ligands for quantum dot labeling of the dopamine D2 receptor in live cell cultures.
2019 Pharmacol Biochem Behav Enrichment-induced differences in methamphetamine drug discrimination in male rats.
2019 J Psychopharmacol The role of prefrontal cortex dopamine D2 and D3 receptors in the mechanism of action of venlafaxine and deep brain stimulation in animal models of treatment-responsive and treatment-resistant depression.
2019 May J Ethnopharmacol Rhodiola rosea root extract has antipsychotic-like effects in rodent models of sensorimotor gating.