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Recent literature: D2 receptor antagonist
Date Journal Article title
2019 Feb Synapse Interaction of nicotinic acetylcholine receptors with dopamine receptors in synaptic plasticity of the mouse insular cortex.
2018 Front Psychiatry The Group of Treatment Resistant Schizophrenias. Heterogeneity in Treatment Resistant Schizophrenia (TRS).
2019 Feb Sci Transl Med DP2 antagonism reduces airway smooth muscle mass in asthma by decreasing eosinophilia and myofibroblast recruitment.
2019 Nat Struct Mol Biol Structures of the 5-HT2A receptor in complex with the antipsychotics risperidone and zotepine.
2019 Jan Gastroenterology Effects of Promotility Agents on Gastric Emptying and Symptoms: a Systematic Review and Meta-Analysis.
2019 Jan Eur J Med Chem Synthesis of novel pyrido[1,2-c]pyrimidine derivatives with rigidized tryptamine moiety as potential SSRI and 5-HT1A receptor ligands.
2019 PLoS One Kami-shoyo-san improves ASD-like behaviors caused by decreasing allopregnanolone biosynthesis in an SKF mouse model of autism.
2019 Jan Pharmacology Evaluation of Antidepressant Effects on Recovery of Electrical Field Stimulation-Induced Contractions that have been Suppressed by Clonidine in Isolated Rat Vas Deferens.
2019 Jan Schizophr Bull Potent Dopamine D2 Antagonists Block the Reward-Enhancing Effects of Nicotine in Smokers With Schizophrenia.
2019 Jan Eur Neuropsychopharmacol Acute and chronic PCP attenuate D2 autoreceptor signaling in stantia nigra dopamine neurons.
2019 Jan Brain Struct Funct The lateral preoptic area and ventral pallidum embolden behavior.
2019 Jan J Neurochem Neuronal KIF5b deletion induces striatum-dependent locomotor impairments and defects in membrane presentation of dopamine D2 receptors.
2019 J Asthma Allergy Spotlight on fevipiprant and its potential in the treatment of asthma: evidence to date.
2018 Dec Cortex Dopamine guides competition for cognitive control: Common effects of haloperidol on working memory and response conflict.
2019 Jan Neurosci Lett Validation of the xylazineketamine anesthesia test as a predictor of the emetic potential of pharmacological compounds in rats.
2019 Apr Behav Brain Res Dopamine type 1- and 2-like signaling in the modulation of spatial reference learning and memory.
2019 Jan Neuropharmacology cAMP-producing chemogenetic and adenosine A2a receptor activation inhibits the inwardly rectifying potassium current in striatal projection neurons.
2018 Nov Cureus Acute Dystonia Secondary to Domperidone in a Pediatric Patient.
2019 Jan Pharmacol Biochem Behav Amantadine enhances nigrostriatal and mesolimbic dopamine function in the rat brain in relation to motor and exploratory activity.
2019 Jan Neuropharmacology Selective activation of Dopamine D3 receptors and norepinephrine transporter blockade enhances sustained attention.
2018 PLoS One A role for dopamine in the peripheral sensory processing of a gastropod mollusc.
2019 Apr Behav Brain Res Orexin-A promotes EEG changes but fails to induce anxiety in rats.
2018 Dec J Allergy Clin Immunol Cytokine-induced endogenous production of prostaglandin D2 is essential for human group 2 innate lymphoid cell activation.
2018 PLoS One Exploring the insulin secretory properties of the PGD2-GPR44DP2 axis in vitro and in a randomized phase-1 trial of type 2 diabetes patients.
2018 Dec Exp Clin Psychopharmacol Does antagonism at 5-HT2A receptors potentiate D₂ blockade-induced disruption of conditioned avoidance response?
2018 Dec Neuroimage Increased cerebral blood flow after single dose of antipsychotics in healthy volunteers depends on dopamine D2 receptor density profiles.
2018 J Exp Pharmacol In vitro pharmacological characterization of SPN-810M (molindone).
2019 Exp Neurol Comparison of electroencephalogram (EEG) response to MDPV versus the hallucinogenic drugs MK-801 and ketamine in rats.
2019 Mar Neuropharmacology Dissociative effects of dorsomedial striatum D1 and D2 receptor antagonism in the regulation of anxiety and learned approach-avoidance conflict decision-making.
2019 Neurochem Int Dopamine D1 receptor activation improves adult hippocampal neurogenesis and exerts anxiolytic and antidepressant-like effect via activation of Wntβ-catenin pathways in rat model of Parkinson's disease.
2018 Nov Sci Rep Glutamatergic and dopaminergic modulation of cortico-striatal circuits probed by dynamic calcium imaging of networks reconstructed in microfluidic chips.
2019 Behav Neurosci Differential involvement of D2 and D3 receptors during reinstatement of cocaine-seeking behavior in the Roman high- and low-avoidance rats.
2018 Nov Support Care Cancer Amisulpride prevents nausea and vomiting associated with highly emetogenic chemotherapy: a randomised, double-blind, placebo-controlled, dose-ranging trial.
2019 Jan Life Sci CRTH2 antagonist, CT‑133, effectively alleviates cigarette smoke-induced acute lung injury.
2019 Jan Am J Physiol Regul Integr... Dopamine modulates excitatory transmission to orexin neurons in a receptor type-specific manner.
2019 Pharmacol Biochem Behav The role of dopamine D1- and D2-like receptors related to muscarinic M1 receptors in impulsive choice in high-impulsive and low-impulsive rats.
2018 Nov Exp Mol Med Selective blockade of spinal D2DR by levo-corydalmine attenuates morphine tolerance via pressing PI3KAkt-MAPK signaling in a MOR-dependent manner.
2018 Nov Nat Prod Res α-Mangostin exhibits antidepressant-like effects mediated by the modification of GABAergic, serotonergic and dopaminergic systems.
2018 Nov Viral Immunol Prostaglandin D2 Levels Regulate CD103+ Conventional Dendritic Cell Activation in Neonates During Respiratory Viral Infection.
2018 Nov J Agric Food Chem Effects of Flavored Nonalcoholic Beverages on Transcriptional Activities of Nuclear and Steroid Hormone Receptors: Proof of Concept for Novel Reporter Cell Line PAZ-PPARg.
2018 Expert Opin Pharmacother An evaluation of fevipiprant for the treatment of asthma: a promising new therapy?
2018 Prostaglandins Other Lipi... Comparison of pro-adipogenic effects between prostaglandin (PG) D2 and its stable, isosteric analogue, 11-deoxy-11-methylene-PGD2, during the maturation phase of cultured adipocytes.
2018 Nov ACS Chem Neurosci Ruboxistaurin Reduces Cocaine-Stimulated Increases in Extracellular Dopamine by Modifying Dopamine-Autoreceptor Activity.
2018 Neurochem Res Dopamine D1 Receptor Within Basolateral Amygdala Is Involved in Propofol Relapse Behavior Induced by Cues.
2018 Oct ACS Med Chem Lett New Dopamine D3-Selective Receptor Ligands Containing a 6-Methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol Motif.
2018 Front Integr Neurosci Dopaminergic Modulation of Goal-Directed Behavior in a Rodent Model of Attention-DeficitHyperactivity Disorder.
2019 Jan Physiol Behav Central oxytocin signaling mediates the central orexin-induced visceral antinociception through the opioid system in conscious rats.
2019 Neurochem Int Balance between dopamine and adenosine signals regulates the PKARap1 pathway in striatal medium spiny neurons.
2018 Mol Pharmacol Involvement of 5-HT1A and 5-HT2A Receptors but Not iαi 2-Adrenoceptors in the Acute Electrophysiological Effects of Cariprazine in the Rat Brain In Vivo.
2018 Iran J Psychiatry Low-Dose Quetiapine in the Treatment of SSRI-Induced Bruxism and Mandibular Dystonia: Case Series.
2018 Hum Psychopharmacol A proof-of-principle study of the effect of combined haloperidol and levodopa administration on working memory-related brain activation in humans.
2018 Oct Int J Mol Sci Prostaglandin D₂ Induces Ca2+ Sensitization of Contraction without Affecting Cytosolic Ca2+ Level in Bronchial Smooth Muscle.
2018 Behav Neurosci Blockade of dopamine D₁ receptors, but not D₂ receptors, decreases motivation in a novel effort-discounting paradigm in common marmosets.
2019 Andrologia Dopamine D2 receptors in the basolateral amygdala modulate erectile function in a rat model of nonorganic erectile dysfunction.
2018 Sep BMC Res Notes Modulation of CaV1.3b L-type calcium channels by M1 muscarinic receptors varies with CaVβ unit expression.
2018 Psychopharmacology (Berl) Effects of the T-type calcium channel antagonist Z944 on paired associates learning and locomotor activity in rats treated with the NMDA receptor antagonist MK-801.
2018 J Exp Neurosci Behavioral Mechanisms That Depend on Dopamine and Serotonin in iCaenorhabditis elegansi Interact With the Antipsychotics Risperidone and Aripiprazole.
2018 Dec Brain Res Pregabalin increases food intake through dopaminergic systems in the hypothalamus.
2018 Oct Birth Defects Res Reproductive toxicology studies porting the safety of molindone, a dopamine receptor antagonist.
2018 Sep Environ Sci Technol Quantification of Pharmaceutical Related Biological Activity in Effluents from Wastewater Treatment Plants in UK and Japan.
2018 Psychopharmacology (Berl) Lack of deuterium isotope effects in the antidepressant effects of (R)-ketamine in a chronic social defeat stress model.
2018 Sep Cell Rep Dual Dopaminergic Regulation of Corticostriatal Plasticity by Cholinergic Interneurons and Indirect Pathway Medium Spiny Neurons.
2018 Mov Disord Ecopipam, a D1 receptor antagonist, for treatment of tourette syndrome in children: A randomized, placebo-controlled crossover study.
2018 Front Cell Neurosci Dichotomous Dopaminergic Control of Ventral Pallidum Neurons.
2018 Sep Molecules Synthesis, Structural and Thermal Studies of 3-(1-Benzyl-1,2,3,6-tetrahydropyridin-4-yl)-5-ethoxy-1iHi-indole (D2AAK1_3) as Dopamine D₂ Receptor Ligand.
2018 Neuropsychopharmacol Rep Chemokine CXCL1 is responsible for cocaine-induced reward in mice.
2019 Jan Behav Brain Res Dopamine D1 and D2 receptor antagonism during development alters later behavior in zebrafish.
2018 Neuropharmacology Antagonism of the D2 dopamine receptor enhances tremor but reduces voluntary muscle activation in humans.
2018 Oct Eur J Pharmacol Histamine H4 receptor mediates chemotaxis of human lung mast cells.
2018 Nov J Biomol Struct Dyn Molecular dynamics simulation of biased agonists at the dopamine D2 receptor suggests the mechanism of receptor functional selectivity.
2018 Aug Eur J Haematol Interleukin-1 receptor antagonist as a biomarker of sepsis in neutropenic haematological patients.
2018 Aug Blood Adv A phase 1 trial evaluating thioridazine in combination with cytarabine in patients with acute myeloid leukemia.
2018 Aug Drug Res (Stuttg) Investigation of Antidepressant, Anxiolytic and Sedative Activities of the Aqueous Leaf Extract of Musa sapientum Linn. (Banana; Musaceae).
2019 Drug Res (Stuttg) Butanol Fraction of Olax Subscorpioidea Produces Antidepressant Effect: Evidence for the Involvement of Monoaminergic Neurotransmission.
2018 Nov Behav Brain Res Involvement of D1- and D2-like dopamine receptors in the dentate gyrus in the acquisition, expression, and extinction of the morphine-induced conditioned place preference in rats.