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Recent literature: Reverse transcriptase inhibitor
Date Journal Article title
2020 Mar J Biomol Struct Dyn Anti-HIV potential of diarylpyrimidine derivatives as non-nucleoside reverse transcriptase inhibitors: Design, synthesis, docking, TOPKAT analysis and molecular dynamics simulations.
2020 Mar J Neuroimmune Pharmacol Associations between Antiretrovirals and Cognitive Function in Women with HIV.
2020 Mar Pharmacol Rep Aloe emodin inhibits telomerase activity in breast cancer cells: transcriptional and enzymological mechanism.
2020 Mar J Org Chem DABCO-Catalyzed MichaelAlkylation Cascade Reactions Involving α-Substituted Ammonium Ylides for the Construction of Spirocyclopropyl Oxindoles: Access to the Powerful Chemical Leads against HIV-1.
2020 Mar BMJ Open Antiretroviral drug class and anaemia risk in the current treatment era among people living with HIV in the USA: a clinical cohort study.
2020 Am J Transl Res Grainyhead-like 2 as a double-edged sword in development and cancer.
2020 Feb Drug Metab Pharmacokinet Synthesis and evaluation of nevirapine analogs to study the metabolic activation of nevirapine.
2020 Mar Viruses The Determination of HIV-1 RT Mutation Rate, Its Possible Allosteric Effects, and Its Implications on Drug Resistance.
2020 Drugs Context Pharmaceutical, clinical, and resistance information on doravirine, a novel non-nucleoside reverse transcriptase inhibitor for the treatment of HIV-1 infection.
2020 Int J Biol Sci Therapeutic Targeting of CDK7 Suppresses Tumor Progression in Intrahepatic Cholangiocarcinoma.
2020 Mar Clin Exp Ophthalmol MiR-1246 promotes anti-apoptotic effect of mini-αA in oxidative stress-induced apoptosis in retinal pigment epithelial cells.
2020 Jan Mol Ther Nucleic Acids Tumor-Suppressive MicroRNA-216b Binds to TPX2, Activating the p53 Signaling in Human Cutaneous Squamous Cell Carcinoma.
2020 Apr AIDS Plasma nucleotide reverse transcriptase inhibitor concentration and their associations with liver and renal parameters in people living with HIV.
2020 Feb Mol Ther Nucleic Acids Long Noncoding RNA RC3H2 Facilitates Cell Proliferation and Invasion by Targeting MicroRNA-101-3pEZH2 Axis in OSCC.
2020 Drugs Today (Barc) Doravirine: a new non-nucleoside reverse transcriptase inhibitor for the treatment of HIV infection.
2020 Mar Int J Cancer Adefovir dipivoxil induces DNA replication stress and augments ATR inhibitor related cytotoxicity.
2020 Mar Eur J Pharm Sci Combining biorelevant in vitro and in silico tools to investigate the in vivo performance of the amorphous solid dispersion formulation of etravirine in the fed state.
2020 Mar ACS Omega Click Chemistry-Based Two-Component System for Efficient Inhibition of Human Immunodeficiency Virus (HIV) Reverse Transcriptase (RT).
2020 Mar AIDS Res Hum Retroviruses Drug Resistance among Adolescents and Young Adults with Virologic Failure of First Line ART and Response to Second Line Treatment.
2020 Mar N Engl J Med Long-Acting Cabotegravir and Rilpivirine for Maintenance of HIV-1 Suppression.
2020 Cell Death Discov Inhibition of IκBα phosphorylation potentiates regulated cell death induced by azidothymidine in HTLV-1 infected cells.
2020 Feb Viruses Molecular Epidemiology of HIV-1 Infected Migrants Followed up in Portugal: Trends between 2001-2017.
2020 Jan StatPearls Nevirapine
2020 Ethiop J Health Sci Characterization of HIV-1 Integrase Gene and Resistance Associated Mutations Prior to Roll out of Integrase Inhibitors by Kenyan National HIV-Treatment Program in Kenya.
2020 Mar J Basic Microbiol Yansuanmalingua inhibits replication of type 2 porcine reproductive and respiratory syndrome virus via activating the caspase-8 apoptosis pathway.
2020 Feb Molecules Design of Biphenyl-Substituted Diarylpyrimidines with a Cyanomethyl Linker as HIV-1 NNRTIs via a Molecular Hybridization Strategy.
2020 Mar Org Lett Nine-Step Stereoselective Synthesis of Islatravir from Deoxyribose.
2020 Acta Pharm Sin B Improving the positional adaptability: structure-based design of biphenyl-stituted diaryltriazines as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
2019 J Oncol DNA Hypermethylation Downregulates Telomerase Reverse Transcriptase (TERT) during iH. pylorii-Induced Chronic Inflammation.
2020 Feb AIDS Increased monocyte and T-cell activation in treated HIV+ ugandan children: associations with gut alteration and HIV factors.
2020 Feb Antimicrob Agents Chemother Discordance between Etravirine Phenotype and Genotype-based Predicted Phenotype for Subtype C HIV-1 from First-line Antiretroviral Therapy Failures in South Africa.
2020 Feb AAPS PharmSciTech Comparative Bioavailability of Oral Granule Formulations of the HIV Antiretroviral Drugs Doravirine, Lamivudine, and Tenofovir Disoproxil Fumarate.
2020 Curr HIV/AIDS Rep Novel Antiretroviral Agents.
2020 Medicine (Baltimore) High resistance to reverse transcriptase inhibitors among persons infected with human immunodeficiency virus type 1 type circulating recombinant form 02_AG in Ghana and on antiretroviral therapy.
2020 Nat Prod Bioprospect Daphnane Diterpenoids from Trigonostemon lii and Inhibition Activities Against HIV-1.
2020 Feb BMC Infect Dis The S68G polymorphism is a compensatory mutation associated with the drug resistance mutation K65R in CRF01_AE strains.
2020 Jan J Acquir Immune Defic Syndr Increased Mortality with Delayed and Missed Switch to Second-Line Antiretroviral Therapy in South Africa.
2020 Feb Cell Biol Int Microtubule stabilizer epothilone B as a motor neuron differentiation agent for human endometrial stem cells.
2020 Braz Oral Res Smad15 signal transduction regulates the ameloblastic differentiation of induced pluripotent stem cells.
2020 Anesthesiology Aldosterone Synthase in Peripheral Sensory Neurons Contributes to Mechanical Hypersensitivity during Local Inflammation in Rats.
2020 Jan AIDS Res Ther Comparison of HIV drug resistance profiles across HIV-1 types A and D for patients receiving a tenofovir-based and zidovudine-based first line regimens in Uganda.
2020 Mar Eur J Med Chem Discovery, synthesis, and optimization of an N-alkoxy indolylacetamide against HIV-1 carrying NNRTI-resistant mutations from the Isatis indigotica root.
2020 Niger Postgrad Med J The role of immune restoration using highly active antiretroviral therapy in the management of AIDS-related Kaposi's sarcoma coexisting with pulmonary tuberculosis.
2020 Jan Curr HIV Res Binding Insight of Anti-HIV Phytocompounds with Prime Targets of HIV: A Molecular Dynamics Simulation Analysis.
2020 Jan Virchows Arch ALK-rearranged renal cell carcinoma with a novel PLEKHA7-ALK translocation and metanephric adenoma-like morphology.
2020 Curr Opin HIV AIDS Antiretroviral therapy in older people with HIV.
2020 Mar Antimicrob Agents Chemother Antiviral Activity of Tenofovir Alafenamide against HIV-1 with Thymidine Analog-Associated Mutations and M184V.
2020 EBioMedicine Foxf1 knockdown promotes BMSC osteogenesis in part by activating the Wntβ-catenin signalling pathway and prevents ovariectomy-induced bone loss.
2020 Jan J Invest Dermatol Molecular and Cellular Responses to the TYK2JAK1 Inhibitor PF-06700841 Reveal Reduction of Skin Inflammation in Plaque Psoriasis.
2020 Jan J Virol Long-acting rilpivirine (RPV LA) pre-exposure prophylaxis does not inhibit vaginal transmission of RPV-resistant HIV-1 nor select for high frequency drug resistance in humanized mice.
2020 Expert Opin Pharmacother Evaluating emtricitabine + rilpivirine + tenofovir alafenamide in combination for the treatment of HIV-infection.
2020 Jan Nat Commun Maximizing the ovarian reserve in mice by evading LINE-1 genotoxicity.
2020 Eur Respir J The NLRP3 inflammasome pathway is activated in sarcoidosis and involved in granuloma formation.
2020 Jan Phys Chem Chem Phys Concerted hydrolysis mechanism of HIV-1 natural strate against types B and C-SA PR: insight through molecular dynamics and hybrid QMMM studies.
2020 Antiviral Res Identification and characterization of a novel hepatitis B virus pregenomic RNA encapsidation inhibitor.
2019 Biomed Res Int The Potential Role of Cycloastragenol in Promoting Diabetic Wound Repair In Vitro.
2020 PLoS One High failure rates of protease inhibitor-based antiretroviral treatment in rural Tanzania - A prospective cohort study.
2020 Int J Antimicrob Agents Retrospective study on the outcome of two-drug regimens based on dolutegravir plus one reverse transcriptase inhibitor in virologically-pressed HIV-infected patients.
2020 EClinicalMedicine Trend of HIV-1 drug resistance in China: A systematic review and meta-analysis of data accumulated over 17 years (2001-2017).
2020 Jan Clin Sci (Lond) The TERT copy number gain is sensitive to telomerase inhibitors in human melanoma.
2020 FASEB J Proliferation of adult human bronchial epithelial cells without a telomere maintenance mechanism for over 200 population doublings.
2020 Lancet HIV Safety, pharmacokinetics, and antiretroviral activity of islatravir (ISL, MK-8591), a novel nucleoside reverse transcriptase translocation inhibitor, following single-dose administration to treatment-naive adults infected with HIV-1: an open-label, phase 1b, consecutive-panel trial.
2020 Jan Clin Infect Dis Efficacy and Safety of Switching to DolutegravirLamivudine Fixed-Dose Two-Drug Regimen Versus Continuing a Tenofovir Alafenamide-Based Three- or Four-Drug Regimen for Maintenance of Virologic Suppression in Adults With HIV-1: Phase 3, Randomized, Non-inferiority TANGO Study.
2020 Mar Cancer Res Epigenetic Targeting of iTERTi-Associated Gene Expression Signature in Human Neuroblastoma with iTERTi Overexpression.
2020 Apr AIDS Challenges of scale-up to dolutegravir-based regimens in -Saharan Africa.
2020 Infection Pregnancy and neonatal outcomes in women with HIV-1 exposed to integrase inhibitors, protease inhibitors and non-nucleoside reverse transcriptase inhibitors: an observational study.
2019 Dec Molecules β-Caryophyllene, a CB2-Receptor-Selective Phytocannabinoid, Suppresses Mechanical Allodynia in a Mouse Model of Antiretroviral-Induced Neuropathic Pain.
2019 Dec HIV Med Retinol-binding protein 4 (RBP4), a potential biomarker of frailty in HIV-infected people on stable antiretroviral therapy.
2020 Jan Acc Chem Res Cutting into the Substrate Dominance: Pharmacophore and Structure-Based Approaches toward Inhibiting Human Immunodeficiency Virus Reverse Transcriptase-Associated Ribonuclease H.
2019 Oct Pharmacoeconomic Review R...
2019 Nov S Afr Med J Descriptive analysis of World Health Organization-recommended second-line antiretroviral treatment: A retrospective cohort data analysis.
2020 Drugs DolutegravirLamivudine Single-Tablet Regimen: A Review in HIV-1 Infection.
2020 Biomaterials Rilpivirine-associated aggregation-induced emission enables cell-based nanoparticle tracking.
2019 Rev Chilena Infectol [Efectiveness and safety of switching to raltegravir-based regimen in dyslipidemic HIV-infected patients receiving antiretroviral therapy at Arriaran Foundation].
2019 Dec J Basic Clin Physiol Phar... Profile of sociodemographics, sources of infection, antiretrovirals and CD4 counts on HIVAIDS outpatients in Turen Primary Health Centre, Indonesia.