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Recent literature: Cholinesterase inhibitor
Date Journal Article title
2019 Jun J Sci Food Agric Innovative perspectives on Pulicaria dysenterica extracts: Phyto-pharmaceutical properties, chemical characterization and multivariate analysis.
2019 Jun Bioorg Chem Synthesis and biological evaluation of indoloquinoline alkaloid cryptolepine and its bromo-derivative as dual cholinesterase inhibitors.
2019 Jun Int J Hyg Environ Health Associations of acetylcholinesterase activity with depression and anxiety symptoms among adolescents growing up near pesticide spray sites.
2019 Jun Chem Biol Interact Flavanone glycosides inhibit β-site amyloid precursor protein cleaving enzyme 1 and cholinesterase and reduce Aβ aggregation in the amyloidogenic pathway.
2019 Jun ChemMedChem Experimental and computational evaluation of some piperonylic acid derived hydrazones bearing isatin moiety as dual inhibitors of cholinesterases and monoamine oxidases.
2019 Jun Bioorg Med Chem Naphthalene-triazolopyrimidine hybrid compounds as potential multifunctional anti-Alzheimer's agents.
2019 Jun Toxicology Respiratory failure triggered by cholinesterase inhibitors may involve activation of a reflex sensory pathway by acetylcholine spillover.
2019 May Mol Med Rep Pharmacokinetics, excretion and metabolites analysis of DL0410, a dual‑acting cholinesterase inhibitor and histamine‑3 receptor antagonist.
2019 Jun Am J Addict Double-Blind Placebo-Controlled Trial of Galantamine for Methadone-Maintained Individuals With Cocaine Use Disorder: Secondary Analysis of Effects on Illicit Opioid Use.
2019 Jun JCI Insight Immunomodulatory role of non-neuronal cholinergic signaling in myocardial injury.
2019 Jun Geriatr Psychol Neuropsyc... Lewy body dementia: therapeutic propositions according to evidence based medicine and practice.
2019 Clin Exp Rheumatol Acetylcholinesterase-associated inflammation in patients with giant cell arteritis. Evaluation by histology and 11C-donepezil PETCT.
2019 Jun Am J Clin Nutr Prognostic significance of serum cholinesterase in patients with acute decompensated heart failure: a prospective comparative study with other nutritional indices.
2019 May Bioorg Chem Design, synthesis and biological activity of novel tacrine-isatin Schiff base hybrid derivatives.
2019 Sep Anal Chim Acta A novel on-flow mass spectrometry-based dual enzyme assay.
2019 Sep Neuropharmacology New evidence for dual binding site inhibitors of acetylcholinesterase as improved drugs for treatment of Alzheimer's disease.
2019 Ment Health Clin Donepezil-induced QTc prolongation: A case report.
2019 Sep J Pharm Biomed Anal Influence of different extraction techniques on the chemical profile and biological properties of Anthemis cotula L.: Multifunctional aspects for potential pharmaceutical applications.
2019 May J Psychopharmacol The effect of antidementia drugs on mortality in patients with Alzheimer's disease.
2019 May Geriatr Gerontol Int Potentially inappropriate prescribing before and after initiation of medicines for dementia: An Australian population-based study.
2019 Bioorg Chem Highly selective carbamate-based butyrylcholinesterase inhibitors derived from a naturally occurring pyranoisoflavone.
2019 May Orphanet J Rare Dis Safety and efficacy of mTOR inhibitor treatment in patients with tuberous sclerosis complex under 2 years of age - a multicenter retrospective study.
2019 May BMC Neurol Peripheral vascular responses to acetylcholine as a predictive tool for response to cholinesterase inhibitors in Alzheimer's disease.
2019 Jul Eur J Med Chem Multi-targeted ChEI-copper chelating molecules as neuroprotective agents.
2019 J Crit Care Effect of physostigmine on recovery from septic shock following intra-abdominal infection - Results from a randomized, double-blind, placebo-controlled, monocentric pilot trial (Anticholium® per Se).
2019 Jul Eur J Med Chem Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents.
2019 Bioorg Chem Isolation, identification, and quantification of Pentylcurcumene from Geophila repens: A new class of cholinesterase inhibitor for Alzheimer's disease.
2019 Microb Pathog Cholinesterase's activities of infected mice by Brucella ovis.
2019 Pestic Biochem Physiol Acaricidal activity, biochemical effects and molecular docking of some monoterpenes against two-spotted spider mite (Tetranychus urticae Koch).
2019 Apr Molecules QuinoxalineTacrine QT78, a Cholinesterase Inhibitor as a Potential Ligand for Alzheimer's Disease Therapy.
2019 Clin Interv Aging Effect of genetic polymorphisms on Alzheimer's disease treatment outcomes: an update.
2019 Apr Pharmacol Res Improvements of symptoms of Alzheimer`s disease by inhibition of the angiotensin system.
2019 Alzheimers Dement (N Y) No synergistic effect of therapeutic doses of donepezil and EVP-6124 in healthy elderly jects in a scopolamine challenge model.
2019 Apr Molecules Potential Pharmacokinetic Drug⁻Drug Interaction Between Harmine, a Cholinesterase Inhibitor, and Memantine, a Non-Competitive iNi-Methyl-d-Aspartate Receptor Antagonist.
2019 Apr BMC Geriatr Continuation versus discontinuation of treatment for severe dementia: randomized, pragmatic, open-label, clinical trial to evaluate the efficacy of continuing drug treatment in patients with severe dementia (STOP-DEM).
2019 Apr Chem Commun (Camb) A laser-induced TiO2-decorated graphene photoelectrode for sensitive photoelectrochemical biosensing.
2019 Bioorg Chem Design, synthesis and evaluation of a novel metal chelator as multifunctional agents for the treatment of Alzheimer's disease.
2019 Apr Brain Behav Immun Pyridostigmine bromide and stress interact to impact immune function, cholinergic neurochemistry and behavior in a rat model of Gulf War Illness.
2019 Adv Ther A 48-Week, Multicenter, Open-Label, Observational Study Evaluating Oral Rivastigmine in Patients with Mild-to-Moderate Alzheimer's Disease in Taiwan.
2019 Apr Molecules Design, Synthesis, and In Vitro Biological Activities of a Bio-Oxidizable Prodrug to Deliver Both ChEs and DYRK1A Inhibitors for AD Therapy.
2019 Jun J Pharm Biomed Anal Multidirectional insights into the biochemical and toxicological properties of Bougainvillea glabra (Choisy.) aerial parts: A functional approach for bioactive compounds.
2019 Eur J Nucl Med Mol Imaging Clinical impact of [18F]flutemetamol PET among memory clinic patients with an unclear diagnosis.
2019 May Bioorg Med Chem Lett Bioactivity-guided identification of flavonoids with cholinesterase and β-amyloid peptide aggregation inhibitory effects from the seeds of Millettia pachycarpa.
2019 Int J Geriatr Psychiatry Antidementia medication use by aged care facility residents with dementia.
2019 J Alzheimers Dis Assessment of 18F-Florbetaben Amyloid PET Imaging in Patients with Suspected Alzheimer's Disease and Isolated Increase in Cerebrospinal Fluid Tau Proteins.
2019 May J Ethnopharmacol In vivo and in vitro metabolism and pharmacokinetics of cholinesterase inhibitor deoxyvasicine from aerial parts of Peganum harmala Linn in rats via UPLC-ESI-QTOF-MS and UPLC-ESI-MSMS.
2019 Mar Neurotoxicology Pretreatment with pyridostigmine bromide has no effect on seizure behavior or 24 hour survival in the rat model of acute diisopropylfluorophosphate intoxication.
2019 Apr Eur J Med Chem Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease.
2019 Feb Molecules Synthesis and AChE-Inhibitory Activity of New Benzimidazole Derivatives.
2019 Apr Eur J Med Chem Design, synthesis, and evaluation of isoflavone analogs as multifunctional agents for the treatment of Alzheimer's disease.
2019 Feb Curr Alzheimer Res Donepezil Derivatives Targeting Amyloid-β cascade in Alzheimer's Disease.
2019 Mar Pollut Bull Inihibition of mullet (M. liza) brain acetylcholinesterase activity by in vitro polycyclic aromatic hydrocarbon exposure.
2019 May Ecotoxicol Environ Saf Brain acetylcholinesterase of three perciformes: From the characterization to the in vitro effect of metal ions and pesticides.
2019 Apr Life Sci Linarin improves the dyskinesia recovery in Alzheimer's disease zebrafish by inhibiting the acetylcholinesterase activity.
2019 Chem Biodivers Clinanthus microstephium, an Amaryllidaceae Species with Cholinesterase Inhibitor Alkaloids: Structure-Activity Analysis of Haemanthamine Skeleton Derivatives.
2019 Apr Life Sci Cholinergic drugs ameliorate endothelial dysfunction by decreasing O-GlcNAcylation via M3 AChR-AMPK-ER stress signaling.
2019 Apr Eur J Med Chem Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase.
2019 Front Neurosci Cholinergic Potentiation Alters Perceptual Eye Dominance Plasticity Induced by a Few Hours of Monocular Patching in Adults.
2019 Mar Bioorg Med Chem Highly potent and selective aryl-1,2,3-triazolyl benzylpiperidine inhibitors toward butyrylcholinesterase in Alzheimer's disease.
2019 Feb Exp Mol Med Inhibition of β-site amyloid precursor protein cleaving enzyme 1 and cholinesterases by pterosins via a specific structure-activity relationship with a strong BBB permeability.
2019 Feb J Cell Biochem Molecular interaction of investigational ligands with human brain acetylcholinesterase.
2019 Mar Bioorg Med Chem Anti-cholinesterase hybrids as multi-target-directed ligands against Alzheimer's disease (1998-2018).
2019 J Enzyme Inhib Med Chem Inhibition of acetylcholinesterase and butyrylcholinesterase with uracil derivatives: kinetic and computational studies.
2019 J Enzyme Inhib Med Chem 4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis.
2019 J Enzyme Inhib Med Chem Discovery of novel dual-active 3-(4-(dimethylamino)phenyl)-7-aminoalcoxy-coumarin as potent and selective acetylcholinesterase inhibitor and antioxidant.
2019 Feb Behav Pharmacol The muscarinic agonist pilocarpine modifies cocaine-reinforced and food-reinforced responding in rats: comparison with the cholinesterase inhibitor tacrine.
2019 Neurogastroenterol Motil Influence of itopride and domperidone on gastric tone and on the perception of gastric distention in healthy jects.
2018 Dec Ter Arkh Ipidacrine in combination therapy regimens of functional constipation.
2019 Feb ACS Appl Mater Interfaces A Luminescence Turn-On Assay for Acetylcholinesterase Activity and Inhibitor Screening Based on Supramolecular Self-Assembly of Alkynylplatinum(II) Complexes on Coordination Polymer.
2019 J Alzheimers Dis Treatment Combinations for Alzheimer's Disease: Current and Future Pharmacotherapy Options.
2019 Mar Eur J Med Chem Indazolylketones as new multitarget cannabinoid drugs.
2019 Mar Phytomedicine Secondary metabolite profiling, cytotoxicity, anti-inflammatory potential and in vitro inhibitory activities of Nardostachys jatamansi on key enzymes linked to hyperglycemia, hypertension and cognitive disorders.
2019 Jan Molecules Small Multitarget Molecules Incorporating the Enone Moiety.
2019 Ticks Tick Borne Dis Molecular evidence for the inhibition of cytochrome p450s and cholinesterases in ticks by the repellent DEET.
2019 Bioorg Chem One-pot four-component synthesis of thiazolidin-2-imines using CuIZnII dual catalysis: A new class of acetylcholinesterase inhibitors.