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Recent literature: Cholinesterase inhibitor
Date Journal Article title
2019 Apr Molecules QuinoxalineTacrine QT78, a Cholinesterase Inhibitor as a Potential Ligand for Alzheimer's Disease Therapy.
2019 Clin Interv Aging Effect of genetic polymorphisms on Alzheimer's disease treatment outcomes: an update.
2019 Apr Pharmacol Res Improvements of Symptoms of Alzheimer`s Disease by Inhibition of the Angiotensin System.
2019 Alzheimers Dement (N Y) No synergistic effect of therapeutic doses of donepezil and EVP-6124 in healthy elderly jects in a scopolamine challenge model.
2019 Apr Molecules Potential Pharmacokinetic Drug⁻Drug Interaction Between Harmine, a Cholinesterase Inhibitor, and Memantine, a Non-Competitive iNi-Methyl-d-Aspartate Receptor Antagonist.
2019 Apr BMC Geriatr Continuation versus discontinuation of treatment for severe dementia: randomized, pragmatic, open-label, clinical trial to evaluate the efficacy of continuing drug treatment in patients with severe dementia (STOP-DEM).
2019 Mar Bioorg Chem Design, synthesis and evaluation of a novel metal chelator as multifunctional agents for the treatment of Alzheimer's disease.
2019 Apr Brain Behav Immun Pyridostigmine bromide and stress interact to impact immune function, cholinergic neurochemistry and behavior in a rat model of Gulf War Illness.
2019 Apr Adv Ther A 48-Week, Multicenter, Open-Label, Observational Study Evaluating Oral Rivastigmine in Patients with Mild-to-Moderate Alzheimer's Disease in Taiwan.
2019 Apr Br J Pharmacol Sex as a biological variable in the pathology and pharmacology of neurodegenerative and neurovascular diseases.
2019 Apr Molecules Design, Synthesis, and In Vitro Biological Activities of a Bio-Oxidizable Prodrug to Deliver Both ChEs and DYRK1A Inhibitors for AD Therapy.
2019 Mar J Pharm Biomed Anal Multidirectional insights into the biochemical and toxicological properties of Bougainvillea glabra (Choisy.) aerial parts: A functional approach for bioactive compounds.
2019 Mar Eur J Nucl Med Mol Imaging Clinical impact of [18F]flutemetamol PET among memory clinic patients with an unclear diagnosis.
2019 May Bioorg Med Chem Lett Bioactivity-guided identification of flavonoids with cholinesterase and β-amyloid peptide aggregation inhibitory effects from the seeds of Millettia pachycarpa.
2019 Mar Int J Geriatr Psychiatry Anti-dementia medication use by aged care residents with dementia.
2019 J Alzheimers Dis Assessment of 18F-Florbetaben Amyloid PET Imaging in Patients with Suspected Alzheimer's Disease and Isolated Increase in Cerebrospinal Fluid Tau Proteins.
2019 May J Ethnopharmacol In vivo and in vitro metabolism and pharmacokinetics of cholinesterase inhibitor deoxyvasicine from aerial parts of Peganum harmala Linn in rats via UPLC-ESI-QTOF-MS and UPLC-ESI-MSMS.
2019 Mar Neurotoxicology Pretreatment with pyridostigmine bromide has no effect on seizure behavior or 24 hour survival in the rat model of acute diisopropylfluorophosphate intoxication.
2019 Feb Curr Alzheimer Res Donepezil Derivatives Targeting Amyloid-β cascade in Alzheimer's Disease.
2019 Mar Pollut Bull Inihibition of mullet (M. liza) brain acetylcholinesterase activity by in vitro polycyclic aromatic hydrocarbon exposure.
2019 May Ecotoxicol Environ Saf Brain acetylcholinesterase of three perciformes: From the characterization to the in vitro effect of metal ions and pesticides.
2019 Apr Life Sci Linarin improves the dyskinesia recovery in Alzheimer's disease zebrafish by inhibiting the acetylcholinesterase activity.
2019 Feb Chem Biodivers Clinanthus microstephium, an Amaryllidaceae Species with Cholinesterase Inhibitor Alkaloids: Structure-Activity Analysis of Haemanthamine Skeleton Derivatives.
2019 Apr Life Sci Cholinergic drugs ameliorate endothelial dysfunction by decreasing O-GlcNAcylation via M3 AChR-AMPK-ER stress signaling.
2019 Apr Eur J Med Chem Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase.
2019 Front Neurosci Cholinergic Potentiation Alters Perceptual Eye Dominance Plasticity Induced by a Few Hours of Monocular Patching in Adults.
2019 Mar Bioorg Med Chem Highly potent and selective aryl-1,2,3-triazolyl benzylpiperidine inhibitors toward butyrylcholinesterase in Alzheimer's disease.
2019 Feb Exp Mol Med Inhibition of β-site amyloid precursor protein cleaving enzyme 1 and cholinesterases by pterosins via a specific structure-activity relationship with a strong BBB permeability.
2019 Feb J Cell Biochem Molecular interaction of investigational ligands with human brain acetylcholinesterase.
2019 Mar Bioorg Med Chem Anti-cholinesterase hybrids as multi-target-directed ligands against Alzheimer's disease (1998-2018).
2019 J Enzyme Inhib Med Chem Inhibition of acetylcholinesterase and butyrylcholinesterase with uracil derivatives: kinetic and computational studies.
2019 J Enzyme Inhib Med Chem 4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis.
2019 J Enzyme Inhib Med Chem Discovery of novel dual-active 3-(4-(dimethylamino)phenyl)-7-aminoalcoxy-coumarin as potent and selective acetylcholinesterase inhibitor and antioxidant.
2019 Feb Behav Pharmacol The muscarinic agonist pilocarpine modifies cocaine-reinforced and food-reinforced responding in rats: comparison with the cholinesterase inhibitor tacrine.
2019 Neurogastroenterol Motil Influence of itopride and domperidone on gastric tone and on the perception of gastric distention in healthy jects.
2018 Dec Ter Arkh Ipidacrine in combination therapy regimens of functional constipation.
2019 J Alzheimers Dis Treatment Combinations for Alzheimer's Disease: Current and Future Pharmacotherapy Options.
2019 Mar Eur J Med Chem Indazolylketones as new multitarget cannabinoid drugs.
2019 Mar Phytomedicine Secondary metabolite profiling, cytotoxicity, anti-inflammatory potential and in vitro inhibitory activities of Nardostachys jatamansi on key enzymes linked to hyperglycemia, hypertension and cognitive disorders.
2019 Jan Molecules Small Multitarget Molecules Incorporating the Enone Moiety.
2019 Ticks Tick Borne Dis Molecular evidence for the inhibition of cytochrome p450s and cholinesterases in ticks by the repellent DEET.
2019 Bioorg Chem One-pot four-component synthesis of thiazolidin-2-imines using CuIZnII dual catalysis: A new class of acetylcholinesterase inhibitors.
2019 Mar Talanta Electrochemical biosensor based on polyelectrolyte complexes for the determination of reversible inhibitors of acetylcholinesterase.
2019 Bioorg Chem Ursolic and oleanolic acid derivatives with cholinesterase inhibiting potential.
2019 Feb J Pharm Biomed Anal Parentucellia latifolia sp. latifolia: A potential source for loganin iridoids by HPLC-ESI-MSn technique.
2019 Biochem Biophys Rep Metabolic treatment of syndrome linked with Parkinson's disease and hypothalamus pituitary gonadal hormones by turmeric curcumin in Bisphenol-A induced neuro-testicular dysfunction of wistar rat.
2019 Jan Bioorg Med Chem In silico, NMR and pharmacological evaluation of an hydroxyoxindole cholinesterase inhibitor.
2019 J Prev Alzheimers Dis Revisiting the Cholinergic Hypothesis in Alzheimer's Disease: Emerging Evidence from Translational and Clinical Research.
2019 Apr Intern Med Cerebellar Cognitive Affective Syndrome Improved by Donepezil.
2018 PLoS One Cholinesterase inhibitor rivastigmine enhances nerve growth factor-induced neurite outgrowth in PC12 cells via sigma-1 and sigma-2 receptors.
2019 Acta Anaesthesiol Scand Reversal of mivacurium-induced neuromuscular blockade with a cholinesterase inhibitor: A systematic review.
2019 Feb J Pharm Biomed Anal Exploring the halophyte Cistanche phelypaea (L.) Cout as a source of health promoting products: In vitro antioxidant and enzyme inhibitory properties, metabolomic profile and computational studies.
2018 Dec Basic Clin Pharmacol Toxicol Effect of anticholinergic burden on treatment modification, delirium and mortality in newly diagnosed dementia patients starting a cholinesterase inhibitor: A population-based study.
2019 Feb Eur J Med Chem Design and development of some phenyl benzoxazole derivatives as a potent acetylcholinesterase inhibitor with antioxidant property to enhance learning and memory.
2019 Comput Biol Chem Multifunctional approaches to provide potential pharmacophores for the pharmacy shelf: Heracleum sphondylium L. sp. ternatum (Velen.) Brummitt.
2019 Feb Chem Biol Interact Azure B affects amyloid precursor protein metabolism in PS70 cells.
2019 Environ Sci Pollut Res Int A low GLP-1 response among patients treated for acute organophosphate and carbamate poisoning: a comparative cross-sectional study from an agrarian region of Sri Lanka.
2018 Nov Chem Rec Tacrines as Therapeutic Agents for Alzheimer's Disease. IV. The Tacripyrines and Related Annulated Tacrines.
2019 J Enzyme Inhib Med Chem Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer's disease therapy.
2018 Nov Alzheimers Res Ther Insights into globalization: comparison of patient characteristics and disease progression among geographic regions in a multinational Alzheimer's disease clinical program.
2019 Feb J Pharm Biomed Anal A comprehensive appraisal on Crocus chrysanthus (Herb.) Herb. flower extracts with HPLC-MSMS profiles, antioxidant and enzyme inhibitory properties.
2019 Biomed Pharmacother Multi-targeting aurones with monoamine oxidase and amyloid-beta inhibitory activities: Structure-activity relationship and translating multi-potency to neuroprotection.
2018 Neuropsychiatr Dis Treat Memantine treatment for Japanese patients with moderate to severe Alzheimer's disease: a meta-analysis of double-blind, randomized, placebo-controlled trials.
2019 Chem Biodivers Design and Synthesis of Selective Acetylcholinesterase Inhibitors: Arylisoxazole-Phenylpiperazine Derivatives.
2018 Nov Nat Prod Res Design, synthesis and cholinesterase inhibitory activity of α-mangostin derivatives.
2018 Nov Parkinsonism Relat Disord The minimum clinically important difference (MCID) for a falls intervention in Parkinson's: A delphi study.
2019 Anal Bioanal Chem Elemental imaging (LA-ICP-MS) of zebrafish embryos to study the toxicokinetics of the acetylcholinesterase inhibitor naled.
2018 Nov Sci Rep Author Correction: Plant-expressed cocaine hydrolase variants of butyrylcholinesterase exhibit altered allosteric effects of cholinesterase activity and increased inhibitor sensitivity.
2018 Nov Sci Rep Activation of α7 Nicotinic Acetylcholine Receptor Ameliorates Zymosan-Induced Acute Kidney Injury in BALBc Mice.
2018 Can Fam Physician Antidepressant and antipsychotic prescribing in primary care for people with dementia.
2019 J Enzyme Inhib Med Chem Synthesis, preliminarily biological evaluation and molecular docking study of new Olaparib analogues as multifunctional PARP-1 and cholinesterase inhibitors.
2018 Nov BMC Pharmacol Toxicol One-year mortality among hospital survivors of cholinesterase inhibitor poisoning based on Taiwan National Health Insurance Research Database from 2003 to 2012.
2019 Mar J Ethnopharmacol Acetylcholinesterase inhibitor from Anthocleista vogelii leaf extracts.
2018 Nov Med Chem Spirocyclohexadienones as an Uncommon Scaffold for Acetylcholinesterase Inhibitory Activity.
2018 Mediators Inflamm Neostigmine Attenuates Proinflammatory Cytokine Expression in Preoptic Area but Not Choroid Plexus during Lipopolysaccharide-Induced Systemic Inflammation.