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Recent literature: Cholinesterase inhibitor
Date Journal Article title
2019 Feb Eur J Med Chem Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase.
2019 Front Neurosci Cholinergic Potentiation Alters Perceptual Eye Dominance Plasticity Induced by a Few Hours of Monocular Patching in Adults.
2018 Dec Bioorg Med Chem Highly potent and selective aryl-1,2,3-triazolyl benzylpiperidine inhibitors toward butyrylcholinesterase in Alzheimer's disease.
2019 Feb Exp Mol Med Inhibition of β-site amyloid precursor protein cleaving enzyme 1 and cholinesterases by pterosins via a specific structure-activity relationship with a strong BBB permeability.
2019 Feb J Cell Biochem Molecular interaction of investigational ligands with human brain acetylcholinesterase.
2019 Jan Bioorg Med Chem Anti-cholinesterase hybrids as multi-target-directed ligands against Alzheimer's disease (1998-2018).
2019 J Enzyme Inhib Med Chem Inhibition of acetylcholinesterase and butyrylcholinesterase with uracil derivatives: kinetic and computational studies.
2019 J Enzyme Inhib Med Chem 4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis.
2019 J Enzyme Inhib Med Chem Discovery of novel dual-active 3-(4-(dimethylamino)phenyl)-7-aminoalcoxy-coumarin as potent and selective acetylcholinesterase inhibitor and antioxidant.
2019 Feb Behav Pharmacol The muscarinic agonist pilocarpine modifies cocaine-reinforced and food-reinforced responding in rats: comparison with the cholinesterase inhibitor tacrine.
2019 Feb Curr Med Res Opin Lifestyle improvement or anti-dementia drugs in Alzheimer's disease: A comment on Kapaki et al. The cognitive effects of cholinesterase inhibitor treatment in every-day practice. Curr Med Res Opin 2005; 21(6): 871-5.
2019 Jan Neurogastroenterol Motil Influence of itopride and domperidone on gastric tone and on the perception of gastric distention in healthy jects.
2018 Dec Ter Arkh Ipidacrine in combination therapy regimens of functional constipation.
2019 Jan J Alzheimers Dis Treatment Combinations for Alzheimer's Disease: Current And Future Pharmacotherapy Options.
2019 Jan Eur J Med Chem Indazolylketones as new multitarget cannabinoid drugs.
2018 Aug Phytomedicine Secondary metabolite profiling, cytotoxicity, anti-inflammatory potential and in vitro inhibitory activities of Nardostachys jatamansi on key enzymes linked to hyperglycemia, hypertension and cognitive disorders.
2019 Jan Molecules Small Multitarget Molecules Incorporating the Enone Moiety.
2019 Jan Ticks Tick Borne Dis Molecular evidence for the inhibition of cytochrome p450s and cholinesterases in ticks by the repellent DEET.
2019 Bioorg Chem One-pot four-component synthesis of thiazolidin-2-imines using CuIZnII dual catalysis: A new class of acetylcholinesterase inhibitors.
2019 Mar Talanta Electrochemical biosensor based on polyelectrolyte complexes for the determination of reversible inhibitors of acetylcholinesterase.
2018 Dec Bioorg Chem Ursolic and oleanolic acid derivatives with cholinesterase inhibiting potential.
2019 Feb J Pharm Biomed Anal Parentucellia latifolia sp. latifolia: A potential source for loganin iridoids by HPLC-ESI-MSn technique.
2019 Biochem Biophys Rep Metabolic treatment of syndrome linked with Parkinson's disease and hypothalamus pituitary gonadal hormones by turmeric curcumin in Bisphenol-A induced neuro-testicular dysfunction of wistar rat.
2019 Jan Bioorg Med Chem In silico, NMR and pharmacological evaluation of an hydroxyoxindole cholinesterase inhibitor.
2019 J Prev Alzheimers Dis Revisiting the Cholinergic Hypothesis in Alzheimer's Disease: Emerging Evidence from Translational and Clinical Research.
2018 Dec Intern Med Cerebellar Cognitive Affective Syndrome Improved by Donepezil.
2018 PLoS One Cholinesterase inhibitor rivastigmine enhances nerve growth factor-induced neurite outgrowth in PC12 cells via sigma-1 and sigma-2 receptors.
2018 Dec Acta Anaesthesiol Scand Reversal of mivacurium-induced neuromuscular blockade with a cholinesterase inhibitor: A systematic review.
2019 Feb J Pharm Biomed Anal Exploring the halophyte Cistanche phelypaea (L.) Cout as a source of health promoting products: In vitro antioxidant and enzyme inhibitory properties, metabolomic profile and computational studies.
2018 Dec Basic Clin Pharmacol Toxicol Effect of anticholinergic burden on treatment modification, delirium and mortality in newly diagnosed dementia patients starting a cholinesterase inhibitor: A population-based study.
2019 Feb Eur J Med Chem Design and development of some phenyl benzoxazole derivatives as a potent acetylcholinesterase inhibitor with antioxidant property to enhance learning and memory.
2019 Comput Biol Chem Multifunctional approaches to provide potential pharmacophores for the pharmacy shelf: Heracleum sphondylium L. sp. ternatum (Velen.) Brummitt.
2019 Feb Chem Biol Interact Azure B affects amyloid precursor protein metabolism in PS70 cells.
2018 Nov Chem Rec Tacrines as Therapeutic Agents for Alzheimer's Disease. IV. The Tacripyrines and Related Annulated Tacrines.
2019 J Enzyme Inhib Med Chem Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer's disease therapy.
2018 Nov Alzheimers Res Ther Insights into globalization: comparison of patient characteristics and disease progression among geographic regions in a multinational Alzheimer's disease clinical program.
2019 Feb J Pharm Biomed Anal A comprehensive appraisal on Crocus chrysanthus (Herb.) Herb. flower extracts with HPLC-MSMS profiles, antioxidant and enzyme inhibitory properties.
2019 Biomed Pharmacother Multi-targeting aurones with monoamine oxidase and amyloid-beta inhibitory activities: Structure-activity relationship and translating multi-potency to neuroprotection.
2018 Neuropsychiatr Dis Treat Memantine treatment for Japanese patients with moderate to severe Alzheimer's disease: a meta-analysis of double-blind, randomized, placebo-controlled trials.
2019 Chem Biodivers Design and Synthesis of Selective Acetylcholinesterase Inhibitors: Arylisoxazole-Phenylpiperazine Derivatives.
2018 Nov Nat Prod Res Design, synthesis and cholinesterase inhibitory activity of α-mangostin derivatives.
2018 Nov Parkinsonism Relat Disord The minimum clinically important difference (MCID) for a falls intervention in Parkinson's: A delphi study.
2018 Nov Sci Rep Author Correction: Plant-expressed cocaine hydrolase variants of butyrylcholinesterase exhibit altered allosteric effects of cholinesterase activity and increased inhibitor sensitivity.
2018 Nov Sci Rep Activation of α7 Nicotinic Acetylcholine Receptor Ameliorates Zymosan-Induced Acute Kidney Injury in BALBc Mice.
2018 Can Fam Physician Antidepressant and antipsychotic prescribing in primary care for people with dementia.
2019 J Enzyme Inhib Med Chem Synthesis, preliminarily biological evaluation and molecular docking study of new Olaparib analogues as multifunctional PARP-1 and cholinesterase inhibitors.
2018 Nov BMC Pharmacol Toxicol One-year mortality among hospital survivors of cholinesterase inhibitor poisoning based on Taiwan National Health Insurance Research Database from 2003 to 2012.
2018 Nov Med Chem Spirocyclohexadienones as an Uncommon Scaffold for Acetylcholinesterase Inhibitory Activity.
2018 Mediators Inflamm Neostigmine Attenuates Proinflammatory Cytokine Expression in Preoptic Area but Not Choroid Plexus during Lipopolysaccharide-Induced Systemic Inflammation.
2018 Oct Bioorg Chem Molecular-docking-guided design and synthesis of new IAA-tacrine hybrids as multifunctional AChEBChE inhibitors.
2018 Oct Med Sci Monit Epidemiology of Dementia in Elderly Chronic Obstructive Pulmonary Disease Patients Living in China's Northwestern High-Elevation Area.
2019 Jan Eur J Med Chem Investigating alkyl nitrates as nitric oxide releasing precursors of multitarget acetylcholinesterase-monoamine oxidase B inhibitors.
2018 Oct Toxicol Ind Health Serum β-glucuronidase activity as a biomarker for acute cholinesterase inhibitor pesticide poisoning.
2018 Clin Interv Aging Clinical efficacy and safety of donepezil in the treatment of Alzheimer's disease in Chinese patients.
2018 PLoS One Comparison of prescribing practices for older adults treated by female versus male physicians: A retrospective cohort study.
2018 Zh Nevrol Psikhiatr Im S ... [Is it personalized treatment of dementia based on the CYP2D6 gene polymorphism possible?]
2018 Comput Biol Chem Combination of phenolic profiles, pharmacological properties and in silico studies to provide new insights on Silene salsuginea from Turkey.
2018 Oct Int J Environ Health Res In vitro antioxidant and enzyme inhibitory properties of Rubus caesius L.
2018 Oct Org Biomol Chem Synthesis and anticholinesterase activity of 2-stituted-N-alkynylindoles.
2018 Bioinformation Screening and analysis of acetyl-cholinesterase (AChE) inhibitors in the context of Alzheimer's disease.
2018 J Enzyme Inhib Med Chem The insight of in vitro and in silico studies on cholinesterase inhibitors from the roots of Cimicifuga dahurica (Turcz.) Maxim.
2018 Arch Pharm (Weinheim) Novel cinnamic acid-tryptamine hybrids as potent butyrylcholinesterase inhibitors: Synthesis, biological evaluation, and docking study.
2018 Health Place Is the risk of developing Alzheimer's disease really higher in rural areas? A multilevel longitudinal study of 261,669 Australians aged 45 years and older tracked over 11 years.
2018 J Am Med Dir Assoc Predictors of Cholinesterase Discontinuation during the First Year after Nursing Home Admission.
2018 Jan StatPearls Glycopyrrolate
2018 Bioorg Chem Coumarin-dithiocarbamate hybrids as novel multitarget AChE and MAO-B inhibitors against Alzheimer's disease: Design, synthesis and biological evaluation.
2018 Chin J Integr Med Chinese Medicine for Alzheimer's Disease: A Meta-Analysis of Randomized Controlled Trials.
2018 Phytochemistry Three Lycopodium alkaloids from Thai club mosses.
2018 Oct Eur J Med Chem Identification of dual Sigma1 receptor modulatorsacetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents.
2018 Expert Opin Drug Saf The efficacy and safety of memantine for the treatment of Alzheimer's disease.
2018 Sep Molecules Natural Peptides in Drug Discovery Targeting Acetylcholinesterase.
2018 Radiology Altered Nucleus Basalis Connectivity Predicts Treatment Response in Mild Cognitive Impairment.
2019 Comp Biochem Physiol C To... Exposure to low concentration of fluoxetine affects development, behaviour and acetylcholinesterase activity of zebrafish embryos.
2018 Int J Biol Macromol Cholinesterases inhibition studies of biological active compounds from the rhizomes of Alpinia officinarum Hance and in silico molecular dynamics.
2018 Oct J Chromatogr B Analyt Tec... Establishment of a quantitative bioanalytical method for an acetylcholinesterase inhibitor Ethyl 3-(2-(4-fluorophenyl) amino)-4-phenylthiazol-5-yl)-3-oxopropanoate including its physicochemical characterization and in vitro metabolite profiling using Liquid Chromatography-Mass Spectrometry.