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Recent literature: Cholinesterase inhibitor
Date Journal Article title
2020 Mar Toxicol Appl Pharmacol Efficacy of retigabine in ameliorating the brain insult following sarin exposure in the rat.
2020 Mar Bioorg Chem Tacrine-hydroxamate derivatives as multitarget-directed ligands for the treatment of Alzheimer's disease: Design, synthesis, and biological evaluation.
2020 Mar Toxicol Appl Pharmacol Aliskiren and captopril improve cognitive deficits in poorly controlled STZ-induced diabetic rats via amelioration of the hippocampal P-ERK, GSK3β, P-GSK3β pathway.
2020 Mar Molecules A Second Look at the Crystal Structures of iDrosophila melanogasteri Acetylcholinesterase in Complex with Tacrine Derivatives Provides Insights Concerning Catalytic Intermediates and the Design of Specific Insecticides.
2020 Mar Chem Biodivers Design and synthesis of novel arylisoxazole-chromenone carboxamides: Investigation of biological activities associated with Alzheimer's disease.
2020 Mar J Pharm Pharmacol TV 3326 for Alzheimer's dementia: a novel multimodal ChE and MAO inhibitors to mitigate Alzheimer's-like neuropathology.
2020 Front Neurol Primary Progressive Aphasia as a Prodromal State of Dementia With Lewy Bodies: A Case Report.
2020 J Psychiatr Res Donepezil, a cholinesterase inhibitor used in Alzheimer's disease therapy, is actively exported out of the brain by abcb1ab p-glycoproteins in mice.
2020 Harmful Algae Guanitoxin, re-naming a cyanobacterial organophosphate toxin.
2020 Feb Curr Alzheimer Res Mechanisms of Anticholinesterase Interference with Tau Aggregation Inhibitor Activity in a Tau-Transgenic Mouse Model
2020 BMJ Mil Health Early diagnosis of nerve agent exposure with a mobile test kit and implications for medical countermeasures: a trigger to react.
2020 Feb Transl Psychiatry Rivastigmine modifies the α-secretase pathway and potentially early Alzheimer's disease.
2020 Apr Behav Brain Res Improvement of APOE4-dependent non-cognitive behavioural traits by postnatal cholinergic stimulation in female mice.
2020 Mar J Agric Food Chem Novel Cinnamoylated Flavoalkaloids Identified in Tea with Acetylcholinesterase Inhibition Effect.
2020 Feb Alzheimers Dement Impact of deprescribing AChEIs on aggressive behaviors and antipsychotic prescribing.
2020 Jan ACS Omega Discovery of Helminthosporin, an Anthraquinone Isolated from iRumex abyssinicusi Jacq as a Dual Cholinesterase Inhibitor.
2020 Mar Bioorg Med Chem Design, synthesis and biological evaluation of novel carbamates as potential inhibitors of acetylcholinesterase and butyrylcholinesterase.
2020 Feb Chem Commun (Camb) Switching enzyme activity by a temperature responsive inhibitor modified polymer.
2020 Bioorg Chem Design, synthesis and evaluation of pyrazole bearing α-aminophosphonate derivatives as potential acetylcholinesterase inhibitors against Alzheimer's disease.
2019 J Pharmacopuncture An In iVitroi and In iVivoi Cholinesterase Inhibitory Activity of iPistacia khinjuki and iAllium sativumi Essential Oils.
2020 Jan Int J Geriatr Psychiatry Predictors of mortality in Māori, Pacific Island, and European patients diagnosed with dementia at a New Zealand Memory Service.
2020 Mol Med Rep Combining antioxidant astaxantin and cholinesterase inhibitor huperzine A boosts neuroprotection.
2019 Alzheimers Dement (N Y) Comparison of cholinesterase inhibitor safety in real-world practice.
2020 Jan BMC Neurol Cerebro-spinal fluid biomarker levels: phosphorylated tau (T) and total tau (N) as markers for rate of progression in Alzheimer's disease.
2020 J Enzyme Inhib Med Chem Development of potent reversible selective inhibitors of butyrylcholinesterase as fluorescent probes.
2020 Bioelectrochemistry Development of a molecularly imprinted polymer electrochemical sensor and its application for sensitive detection and determination of malathion in olive fruits and oils.
2020 Amino Acids Acetylcholinesterase inhibitory activity of a naturally occurring peptide isolated from Boana pulchella (Anura: Hylidae) and its analogs.
2019 Dec Drug Dev Res Identification of two arylimides as cholinesterase inhibitors and testing of propranolol addition on impaired rat memory.
2020 Feb Eur J Med Chem Apigenin-rivastigmine hybrids as multi-target-directed liagnds for the treatment of Alzheimer's disease.
2020 J Enzyme Inhib Med Chem Design, synthesis, iin vitroi and iin vivoi evaluation of benzylpiperidine-linked 1,3-dimethylbenzimidazolinones as cholinesterase inhibitors against Alzheimer's disease.
2020 Mar J Sci Food Agric Untargeted metabolomic profiling of three Crataegus species (hawthorn) and their in vitro biological activities.
2020 Jan Int J Neurosci Tacrine modulates Kv2.1 channel gene expression and cell proliferation.
2019 Dec Mol Divers Design and synthesis of benzodiazepine-1,2,3-triazole hybrid derivatives as selective butyrylcholinesterase inhibitors.
2020 Fish Shellfish Immunol Anti-foodborne enteritis effect of galantamine potentially via acetylcholine anti-inflammatory pathway in fish.
2019 Restor Neurol Neurosci Cholinergic potentiation of visual perception and vision restoration in rodents and humans.
2019 Dec Drug Dev Res Dual targeting of cholinesterase and amyloid beta with pyridiniumisoquinolium derivatives.
2019 Dec Molecules Chasing ChEs-MAO B Multi-Targeting 4-Aminomethyl-7-Benzyloxy-2iHi-Chromen-2-ones.
2019 Zh Nevrol Psikhiatr Im S ... [The use of donepezil in gait disorders in eldery patients with dementia].
2019 Dec Biotechnol Appl Biochem The antioxidant 2,3-dichloro,5,8-dihydroxy,1,4-naphthoquinone inhibits acetyl-cholinesterase activity and amyloid β42 aggregation: A dual target therapeutic candidate compound for the treatment of Alzheimer's disease.
2020 Feb Chem Pharm Bull (Tokyo) Discovery and Biological Evaluation of New Selective Acetylcholinesterase Inhibitors with Anti-Aβ Aggregation Activity through Molecular Docking-Based Virtual Screening.
2019 Pak J Pharm Sci Design, synthesis and biological Evaluation of Dual acetyl cholinesterase and beta-secretase inhibitors in treatment for alzheimer's Disease.
2019 Dec BMJ Cognitive symptoms of Alzheimer's disease: clinical management and prevention.
2019 PLoS Pathog Novel cholinesterase paralogs of Schistosoma mansoni have perceived roles in cholinergic signalling and drug detoxification and are essential for parasite survival.
2020 Jan Dalton Trans Design, synthesis, characterization of peripherally tetra-pyridine-triazole-stituted phthalocyanines and their inhibitory effects on cholinesterases (AChEBChE) and carbonic anhydrases (hCA I, II and IX).
2019 Dec Med Chem Anti-Cholinesterase Activity of Chalcone Derivatives: Synthesis, In Vitro Assay and Molecular Docking Study.
2020 Feb J Pharm Biomed Anal Unique coated neusilin pellets with a more distinct and fast visual detection of nerve agents and other cholinesterase inhibitors.
2020 Bioorg Chem Design, synthesis and evaluation of novel ferulic acid derivatives as multi-target-directed ligands for the treatment of Alzheimer's disease.
2020 Biochimie Molecular docking and in vitro evaluation of a new hybrid molecule (JM-20) on cholinesterase activity from different sources.
2020 J Enzyme Inhib Med Chem Novel tacrine-benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer's Disease.
2020 Ecotoxicol Environ Saf A comparative study of acetylcholinesterase and general-esterase activity assays using different strates, in vitro and in vivo exposures and model organisms.
2019 J Subst Abuse Treat Randomized placebo-controlled trial of galantamine in individuals with cocaine use disorder.
2019 J Alzheimers Dis Sixteen-Week Interventional Study to Evaluate the Clinical Effects and Safety of Rivastigmine Capsules in Chinese Patients with Alzheimer's Disease.
2019 Nov Invest Ophthalmol Vis Sci IPL Sublamination in Chicken Retinal Spheroids Is Initiated via Müller Cells and Cholinergic Differentiation, and Is Disrupted by NMDA Signaling.
2019 Oct Plants (Basel) Chemical, Enantioselective, and Sensory Analysis of a Cholinesterase Inhibitor Essential Oil from iCoreopsis trilobai S.F. Blake (Asteraceae).
2020 Jan Am J Physiol Gastrointest... Neural motor complexes propagate continuously along the full length of mouse small intestine and colon.
2019 Dec Bioorg Med Chem Lett Discovery of potent and selective butyrylcholinesterase inhibitors through the use of pharmacophore-based screening.
2020 J Enzyme Inhib Med Chem Design, synthesis and evaluation of quinolinone derivatives containing dithiocarbamate moiety as multifunctional AChE inhibitors for the treatment of Alzheimer's disease.
2019 Nov Biomolecules 2-Hydroxy-iNi-phenylbenzamides and Their Esters Inhibit Acetylcholinesterase and Butyrylcholinesterase.
2019 Front Mol Neurosci CSF Cholinergic Index, a New Biomeasure of Treatment Effect in Patients With Alzheimer's Disease.
2019 Pak J Pharm Sci Curcumin lessens unpredictable chronic mild stress-induced depression and memory deficits by modulating oxidative stress and cholinergic activity.
2019 Int J Med Mushrooms Bioactivity-Guided Isolation of Acetylcholinesterase Inhibitor from Ganoderma mediosinense (Agaricomycetes).
2019 Pharmacol Rep A new series of pyridazinone derivatives as cholinesterases inhibitors: Synthesis, in vitro activity and molecular modeling studies.
2020 Jan Eur J Med Chem Search for new multi-target compounds against Alzheimer's disease among histamine H3 receptor ligands.
2019 Curr Alzheimer Res Terpenes and Phenylpropanoids as Acetyl- and Butyrylcholinesterase Inhibitors: A Comparative Study.
2019 Oct Mini Rev Med Chem A Series of New Hydrazone Derivatives: Synthesis, Molecular Docking and Anticholinesterase Activity Studies.
2012 LiverTox: Clinical and Re... Alzheimer Disease Agents
2020 Mar Food Chem Influence of nanoencapsulated lutein on acetylcholinesterase activity: In vitro determination, kinetic parameters, and in silico docking simulations.
2019 Oct JAMA Diagnosis and Management of Dementia: Review.
2020 J Am Geriatr Soc Screening for Adverse Drug Reactions in Dementia Patients on Cholinesterase Inhibitor Therapy.
2020 Pharmacology Sustainable Effects of Distigmine Bromide on Urinary Bladder Contractile Function.
2019 Oct J Med Chem Dual-Acting Cholinesterase-Human Cannabinoid Receptor 2 Ligands Show Pronounced Neuroprotection in Vitro and Overadditive and Disease-Modifying Neuroprotective Effects in Vivo.
2019 Nov J Agric Food Chem Preparation of MatrinicOxymatrinic Amide Derivatives as InsecticidalAcaricidal Agents and Study on the Mechanisms of Action against iTetranychus cinnabarinusi.
2019 Bioorg Chem New 4-N-phenylaminoquinoline derivatives as antioxidant, metal chelating and cholinesterase inhibitors for Alzheimer's disease.
2019 Oct Molecules Two New AChE Inhibitors Isolated from Li Folk Herb Heilaohu "iKadsura coccineai" Stems.
2019 Dec Chem Biol Interact The kinetics of inhibition of human acetylcholinesterase and butyrylcholinesterase by methylene violet 3RAX.