|
2019 Feb |
Eur Psychiatry |
The efficacy of cariprazine in negative symptoms of schizophrenia: Post hoc analyses of PANSS individual items and PANSS-derived factors. |
|
2019 |
PLoS One |
Dissecting the roles of β-arrestin2 and GSK-3 signaling in 5-HT1BR-mediated perseverative behavior and prepulse inhibition deficits in mice. |
|
2019 Jan |
Eur J Med Chem |
Synthesis of novel pyrido[1,2-c]pyrimidine derivatives with rigidized tryptamine moiety as potential SSRI and 5-HT1A receptor ligands. |
|
2019 Jan |
J Clin Psychiatry |
Long-Term Remission With Cariprazine Treatment in Patients With Schizophrenia: A Post Hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Relapse Prevention Trial. |
|
2019 Jan |
J Chem Neuroanat |
Protective effects of 5-HT1A receptor antagonist and 5-HT2A receptor agonist on the biochemical and histological features in a rat model of Alzheimer's disease. |
|
2019 Jan |
J Vet Pharmacol Ther |
Pharmacokinetics and bioavailability after intramuscular injection of the 5-HT1A serotonin agonist R-8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) in domestic goats (Capra aegagrus hircus). |
|
2019 |
Bull Exp Biol Med |
Prenatal Stimulation of 5-HT1A Receptors Improves Adaptive Behavior in Prenatally Stressed Rats. |
|
2018 |
Front Pharmacol |
5-HT1A Receptor Function Makes Wound Healing a Happier Process. |
|
2019 Jan |
ACS Chem Neurosci |
Multitarget 1,4-Dioxane Compounds Combining Favorable D2-like and 5-HT1A Receptor Interactions with Potential for the Treatment of Parkinson's Disease or Schizophrenia. |
|
2019 Jan |
Metab Brain Dis |
Serotonin 5-HT1A receptors modulate depression-related symptoms following mild traumatic brain injury in male adult mice. |
|
2018 Dec |
J Neurosci |
Activation of 5-HT1A receptors promotes retinal ganglion cell function by inhibiting the cAMP-PKA pathway to modulate presynaptic GABA release in chronic glaucoma. |
|
2018 |
Front Cell Neurosci |
Hypidone Hydrochloride (YL-0919) Produces a Fast-Onset Reversal of the Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure. |
|
2018 Dec |
Psychopharmacology (Berl) |
Activation of somatodendritic 5-HT1A autoreceptors reduces the acquisition and expression of cued fear in the rat fear-potentiated startle test. |
|
2019 |
Int Clin Psychopharmacol |
Long-term safety and tolerability of cariprazine as adjunctive therapy in major depressive disorder. |
|
2018 Dec |
Basic Clin Pharmacol Toxicol |
Optimization and pharmacological characterization of receptor-mediated Gio activation in postmortem human prefrontal cortex. |
|
2018 Dec |
Fundam Clin Pharmacol |
Anxiolytic-like effects of the new arylpiperazine derivatives containing isonicotinic and picolinic nuclei: behavioral and biochemical studies. |
|
2018 |
Mov Disord |
Diverse serotonin actions of vilazodone reduce l-3,4-dihidroxyphenylalanine-induced dyskinesia in hemi-parkinsonian rats. |
|
2019 |
Expert Opin Pharmacother |
Evaluation of vilazodone for the treatment of depressive and anxiety disorders. |
|
2019 |
Eur Neuropsychopharmacol |
Efficacy of cariprazine across symptom domains in patients with acute exacerbation of schizophrenia: Pooled analyses from 3 phase IIIII studies. |
|
2018 Nov |
Psychopharmacology (Berl) |
Cannabinoid-induced lower lip retraction in rats. |
|
2019 |
Expert Opin Drug Discov |
Vortioxetine: a novel antidepressant for the treatment of major depressive disorder. |
|
2019 |
Food Chem Toxicol |
5-HT1A receptor agonist 8-OH-DPAT induces serotonergic behaviors in mice via interaction between PKCδ and p47phox. |
|
2018 |
J Pharmacol Sci |
Involvement of 5-HT2A receptor hyperfunction in the anxiety-like behavior induced by doxorubicin and cyclophosphamide combination treatment in rats. |
|
2018 Oct |
Int J Mol Sci |
Oncotoxic Properties of Serotonin Transporter Inhibitors and 5-HT1A Receptor Ligands. |
|
2018 |
Mol Pharmacol |
Involvement of 5-HT1A and 5-HT2A Receptors but Not iαi 2-Adrenoceptors in the Acute Electrophysiological Effects of Cariprazine in the Rat Brain In Vivo. |
|
2018 |
J Exp Neurosci |
Behavioral Mechanisms That Depend on Dopamine and Serotonin in iCaenorhabditis elegansi Interact With the Antipsychotics Risperidone and Aripiprazole. |
|
2019 Feb |
Brain Res |
Breathing stimulation mediated by 5-HT1A and 5-HT3 receptors within the preBötzinger complex of the adult rabbit. |
|
2018 Sep |
Int J Mol Sci |
Deep Brain Stimulation Modified Autism-Like Deficits via the Serotonin System in a Valproic Acid-Induced Rat Model. |
|
2018 Sep |
Sci Rep |
Critical roles of serotonin-oxytocin interaction during the neonatal period in social behavior in 15q dup mice with autistic traits. |
|
2018 Nov |
Neurosci Lett |
Co-activation of both 5-HT1A and 5-HT7 receptors induced attenuation of glutamatergic synaptic transmission in the rat visual cortex. |
|
2018 |
Neuropharmacology |
Reduced cortical serotonin 5-HT2A receptor binding and glutamate activity in high compulsive drinker rats. |
|
2018 Sep |
Handb Exp Pharmacol |
Other Antidepressants. |
|
2018 |
Neuropharmacology |
Role of hippocampal 5-HT1A receptors in the antidepressant-like phenotype of mice expressing RGS-insensitive Gαi2 protein. |
|
2018 |
Neurobiol Aging |
Improved age-related deficits in cognitive performance and affective-like behavior following acute, but not repeated, 8-OH-DPAT treatments in rats: regulation of hippocampal FADD. |
|
2018 |
Expert Opin Ther Pat |
5-HT1A receptor ligands and their therapeutic applications: review of new patents. |
|
2018 |
Neurogastroenterol Motil |
The central effects of buspirone on abdominal pain in rats. |
|
2018 |
eNeuro |
Nausea-Induced 5-HT Release in the Interoceptive Insular Cortex and Regulation by Monoacylglycerol Lipase (MAGL) Inhibition and Cannabidiol. |
|
2018 |
Psychopharmacology (Berl) |
5-HT1A parital agonism and 5-HT7 antagonism restore episodic memory in chronic phencyclidine-treated mice: role of brain glutamate, dopamine, acetylcholine and GABA. |
|
2018 Sep |
Neuropharmacology |
Interplay between 5-HT2C and 5-HT1A receptors in the dorsal periaqueductal gray in the modulation of fear-induced antinociception in mice. |
|
2018 Sep |
Future Med Chem |
Synthesis and biological evaluation of 1,3-dioxolane-based 5-HT1A receptor agonists for CNS disorders and neuropathic pain. |
|
2018 |
Psychopharmacology (Berl) |
The effect of NAD-299 and TCB-2 on learning and memory, hippocampal BDNF levels and amyloid plaques in Streptozotocin-induced memory deficits in male rats. |
|
2018 Jul |
Addict Biol |
Modulation of serotonin and noradrenaline in the BLA by pindolol reduces long-term ethanol intake. |
|
2018 |
Front Neurosci |
5-HT1a Receptor Involvement in Temporal Memory and the Response to Temporal Ambiguity. |
|
2018 Sep |
Neuropharmacology |
5-HT1A receptor-mediated activation of neuroendocrine responses and multiple protein kinase pathways in the peripubertal rat hypothalamus. |
|
2018 |
Psychopharmacology (Berl) |
5-HT3 antagonists decrease discounting rate without affecting sensitivity to reward magnitude in the delay discounting task in mice. |
|
2018 |
Exp Clin Psychopharmacol |
Effects of lorcaserin and buspirone, administered alone and as a mixture, on cocaine self-administration in male and female rhesus monkeys. |
|
2018 |
Pharmacol Biochem Behav |
Neurochemical changes underlying schizophrenia-related behavior in a modified forced swim test in mice. |
|
2018 |
Neuropharmacology |
The GABAergic Gudden's dorsal tegmental nucleus: A new relay for serotonergic regulation of sleep-wake behavior in the mouse. |
|
2018 |
Neuropharmacology |
Enhanced central histaminergic transmission attenuates compulsive-like behavior in mice. |
|
2018 Jun |
Molecules |
Receptor⁻Receptor Interactions in Multiple 5-HT1A Heteroreceptor Complexes in Raphe-Hippocampal 5-HT Transmission and Their Relevance for Depression and Its Treatment. |
|
2018 Oct |
ACS Chem Neurosci |
Dark Classics in Chemical Neuroscience: Mescaline. |
|
2018 |
JAAPA |
Flibanserin for hypoactive sexual desire disorder in premenopausal women. |
|
2018 |
Neuropharmacology |
5-HT6 receptor agonist and memory-enhancing properties of hypidone hydrochloride (YL-0919), a novel 5-HT1A receptor partial agonist and SSRI. |
|
2018 Nov |
Brain Res |
Monoaminergic and aminoacidergic receptors are involved in the antidepressant-like effect of ginsenoside Rb1 in mouse hippocampus (CA3) and prefrontal cortex. |
|
2018 |
Pharmacol Biochem Behav |
Dopamine and serotonin metabolism associated with morphine reward and its inhibition with buspirone: A study in the rat striatum. |
|
2018 |
Brain Struct Funct |
18F-F13640 preclinical evaluation in rodent, cat and primate as a 5-HT1A receptor agonist for PET neuroimaging. |
|
2018 Jul |
Bioorg Med Chem |
Design, synthesis and evaluation of vilazodone-tacrine hybrids as multitarget-directed ligands against depression with cognitive impairment. |
|
2018 |
Exp Neurol |
Ionic plasticity and pain: The loss of descending serotonergic fibers after spinal cord injury transforms how GABA affects pain. |
|
2018 |
Mol Biol (Mosk) |
[Functional Responses to the Chronic Activation of 5-HT1A Receptors in Mice with Genetic Predisposition to Catalepsy]. |
|
2018 |
Pharmacol Biochem Behav |
A behavioral mechanistic investigation of the role of 5-HT1A receptors in the mediation of rat maternal behavior. |
|
2018 Jul |
J Neurophysiol |
Phrenic long-term depression evoked by intermittent hypercapnia is modulated by serotonergic and adrenergic receptors in raphe nuclei. |
|
2018 |
Front Neural Circuits |
Emergence of Serotonergic Neurons After Spinal Cord Injury in Turtles. |
|
2018 |
Neurochem Res |
Effects of the Serotonin 5-HT1A Receptor Biased Agonists, F13714 and F15599, on Striatal Neurotransmitter Levels Following L-DOPA Administration in Hemi-Parkinsonian Rats. |
|
2017 |
Beilstein J Org Chem |
Microfluidic radiosynthesis of [18F]FEMPT, a high affinity PET radiotracer for imaging serotonin receptors. |
|
2018 |
Drug Metab Dispos |
Activation of 5-HT1A Receptors in the Hypothalamic Paraventricular Nuclei Negatively Regulates Cytochrome P450 Expression and Activity in Rat Liver. |
|
2018 Jun |
Brain Res |
NLX-112, a highly selective 5-HT1A receptor agonist, mediates analgesia and antidepressant-like activity in rats via spinal cord and prefrontal cortex 5-HT1A receptors, respectively. |
|
2018 |
Front Psychiatry |
Repeated Exposure to the "Spice" Cannabinoid JWH-018 Induces Tolerance and Enhances Responsiveness to 5-HT1A Receptor Stimulation in Male Rats. |
|
2018 |
Behav Pharmacol |
Estradiol presses ingestive response evoked by activation of 5-HT1A receptors in the lateral hypothalamus of ovariectomized rats. |
|
2018 |
Ann Gastroenterol |
Evaluation and management of esophageal manifestations in systemic sclerosis. |
|
2018 |
Psychiatry Investig |
Effects of 5HT1A Activation on Gating Profile Following 5HT Depletion in Rats Lacking Social Attachment Since Weanling. |
|
2018 |
Neuropsychopharmacology |
Positive regulation of raphe serotonin neurons by serotonin 2B receptors. |
|
2018 |
Br J Pharmacol |
Mechanisms of imidazoline I2 receptor agonist-induced antinociception in rats: involvement of monoaminergic neurotransmission. |
|
2018 |
FASEB J |
NK1R5-HT1AR interaction is related to the regulation of melanogenesis. |
|
2018 Feb |
Sci Rep |
5-HT1A receptor-dependent modulation of emotional and neurogenic deficits elicited by prolonged consumption of alcohol. |
|
2018 |
J Ocul Pharmacol Ther |
Pharmacology of Serotonin Receptors Causing Contraction of Isolated Bovine Posterior Ciliary Arteries: Role in Ocular Blood Flow. |