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Recent literature: CB1 receptor antagonist
Date Journal Article title
2020 Mar Int J Dev Neurosci Adolescent cb1 receptor antagonism influences sequent social interactions and neural activity in female rats.
2020 Mar Physiol Behav Adenosine A1 receptor agonist induces visceral antinociception via 5-HT1A, 5-HT2A, dopamine D1 or cannabinoid CB1 receptors, and the opioid system in the central nervous system.
2020 Mar ACS Chem Neurosci Prediction of the binding affinities and selectivity for CB1 and CB2 ligands using homology modeling, molecular docking, molecular dynamics simulations, and MM-PBSA binding free energy calculations.
2020 Mar Biochem Biophys Res Commun Effect of monoacylglycerol lipase inhibition on intestinal permeability in chronic stress model.
2020 Mar Pharmacol Res Cannabidiol attenuates behavioral changes in a rodent model of schizophrenia through 5-HT1A, but not CB1 and CB2 receptors.
2020 Mar Clin Exp Pharmacol Physiol Stimulation of brain cannabinoid CB1 receptors can ameliorate hypertension in spontaneously hypertensive rats.
2020 Mar Nutr Diabetes Novel CB1 receptor antagonist BAR-1 modifies pancreatic islet function and clinical parameters in prediabetic and diabetic mice.
2020 Feb Psychopharmacology (Berl) Effects of combined 5-HT2A and cannabinoid receptor modulation on a schizophrenia-related prepulse inhibition deficit in mice.
2020 Feb Br J Pharmacol Fatty acid amide hydrolase inhibition in the central nervous system prevents and reverses morphine tolerance in male and female mice.
2020 Feb Braz J Phys Ther The role of spinal inhibitory neuroreceptors in the antihyperalgesic effect of warm water immersion therapy.
2020 Mar Antioxid Redox Signal Enhanced Analgesic Effects and Gastrointestinal Safety of a Novel, Hydrogen Sulfide-Releasing Anti-Inflammatory Drug (ATB-352): A Role for Endogenous Cannabinoids.
2019 Cannabis Cannabinoid Res Pharmacokinetic and Pharmacodynamic Characterization of Tetrahydrocannabinol-Induced Cannabinoid Dependence After Chronic Passive Cannabis Smoke Exposure in Rats.
2020 Feb Cells Neutrophil Chemotaxis and NETosis in Murine Chronic Liver Injury via Cannabinoid Receptor 1 Gαio ROS p38 MAPK Signaling Pathway.
2020 Feb Br J Pharmacol The peripheral CB1 receptor antagonist JD5037 attenuates liver fibrosis via a CB1 receptorβ-arrestin1Akt pathway.
2020 Pharmacol Rep α2-Adrenoceptor agonist induces peripheral antinociception via the endocannabinoid system.
2020 Yakugaku Zasshi [Dependence and Cytotoxicity of Components of Cannabis].
2020 Apr Exp Cell Res The endocannabinoid receptors CB1 and CB2 affect the regenerative potential of adipose tissue MSCs.
2020 Feb Cell Cryo-EM Structure of the Human Cannabinoid Receptor CB2-Gi Signaling Complex.
2020 Jan Shock The Critical Role of Cannabinoid Receptor 2 in URB602-induced Protective Effects Against Renal Ischemia-Reperfusion Injury in the Rat.
2020 Apr Behav Brain Res Endocannabinoids mediate long-lasting behavioural and physiological changes in male rats induced by the repeated activation of the mesolimbic system by copulation to satiety.
2020 Brain Res Bull GABA-cannabinoid interplays in the dorsal hippocampus and basolateral amygdala mediate morphine-induced amnesia.
2020 Jan BMC Biol Control of glutamate release by complexes of adenosine and cannabinoid receptors.
2020 Jan Molecules Allosteric Cannabinoid Receptor 1 (CB1) Ligands Reduce Ocular Pain and Inflammation.
2020 Jan Br J Pharmacol Attenuation of fear-conditioned analgesia in rats by monoacylglycerol lipase inhibition in the anterior cingulate cortex: Potential role for CB2 receptors.
2020 Bratisl Lek Listy Hemopressin increases penicillin-induced epileptiform activity in rats.
2020 Int Immunopharmacol Involvement of endocannabinoid system, inflammation and apoptosis in diabetes induced liver injury: Role of 5-HT3 receptor antagonist.
2020 Jan Psychopharmacology (Berl) Cannabidiol-induced panicolytic-like effects and fear-induced antinociception impairment: the role of the CB1 receptor in the ventromedial hypothalamus.
2020 Jan J Biomed Sci Neuropeptide S-initiated sequential cascade mediated by OX1, NK1, mGlu5 and CB1 receptors: a pivotal role in stress-induced analgesia.
2020 Jan Sleep Breath CB1 receptor antagonist rimonabant protects against chronic intermittent hypoxia-induced bone metabolism disorder and destruction in rats.
2020 Psychopharmacology (Berl) Effect of combined doses of Δ9-tetrahydrocannabinol and cannabidiol or tetrahydrocannabinolic acid and cannabidiolic acid on acute nausea in male Sprague-Dawley rats.
2019 Dec Molecules β-Caryophyllene, a CB2-Receptor-Selective Phytocannabinoid, Suppresses Mechanical Allodynia in a Mouse Model of Antiretroviral-Induced Neuropathic Pain.
2020 Psychoneuroendocrinology Remote CB1 receptor antagonist administration reveals multiple sites of tonic and phasic endocannabinoid neuroendocrine regulation.
2019 Dec Br J Pharmacol β-Caryophyllene, a dietary terpenoid, inhibits nicotine taking and nicotine seeking in rodents.
2019 Cannabis Cannabinoid Res 2-Linoleoylglycerol Is a Partial Agonist of the Human Cannabinoid Type 1 Receptor that Can Suppress 2-Arachidonolyglycerol and Anandamide Activity.
2019 Front Pharmacol Structure-Effect Relationships of Novel Semi-Synthetic Cannabinoid Derivatives.
2019 Dec J Hypertens Vasodilatory effects of cannabidiol in human pulmonary and rat small mesenteric arteries: modification by hypertension and the potential pharmacological opportunities.
2019 Nov J Pain Investigation of the Involvement of the Endocannabinoid System in TENS-Induced Antinociception.
2020 Pharmacol Biochem Behav Influence of the CB1 and CB2 cannabinoid receptor ligands on the activity of atypical antidepressant drugs in the behavioural tests in mice.
2020 Pharmacol Biochem Behav Disrupting the endocannabinoid system in early adolescence negatively impacts sociability.
2019 JACC Basic Transl Sci Alcohol Binge-Induced Cardiovascular Dysfunction Involves Endocannabinoid-CB1-R Signaling.
2019 Dec Eur J Pharmacol Δ9-THC and related cannabinoids press stance P- induced neurokinin NK1-receptor-mediated vomiting via activation of cannabinoid CB1 receptor.
2019 Front Neurosci Pharmacological and Behavioral Effects of the Synthetic Cannabinoid AKB48 in Rats.
2020 Feb Toxicol Lett Synthetic cannabinoids JWH-018, JWH-122, UR-144 and the phytocannabinoid THC activate apoptosis in placental cells.
2020 Neurourol Urodyn Cannabinoid receptor 2 activation decreases severity of cyclophosphamide-induced cystitis via regulating autophagy.
2020 Mar Behav Brain Res Novel object recognition memory in REM sleep-deprived rats: Role of the cannabinoid CB1 receptor.
2020 Neuropharmacology Cannabidiol increases the nociceptive threshold in a preclinical model of Parkinson's disease.
2019 Nov Sci Rep Cannabinoids Exacerbate Alcohol Teratogenesis by a CB1-Hedgehog Interaction.
2019 Chin J Physiol Effects of cannabinoid modulation on hypothalamic nesfatin-1 and insulin resistance.
2020 Apr Biol Psychiatry Cannabinoid Exposure via Lactation in Rats Disrupts Perinatal Programming of the Gamma-Aminobutyric Acid Trajectory and Select Early-Life Behaviors.
2020 J Physiol Biphasic effects of methanandamide on murine gastric vagal afferent mechanosensitivity.
2020 Naunyn Schmiedebergs Arch... Medial prefrontal cortex diclofenac-induced antinociception is mediated through GPR55, cannabinoid CB1, and mu-opioid receptors of this area and periaqueductal gray.
2019 Oct Nutr Neurosci Cannabinoid receptor type 1 modulates the effects of polyunsaturated fatty acids on memory of stressed rats.
2020 Jan Neuropharmacology The novel MAGL inhibitor MJN110 enhances responding to reward-predictive incentive cues by activation of CB1 receptors.
2020 Jan Neuropharmacology Neuropeptide Y and cannabinoids interaction in the amygdala after exposure to shock and reminders model of PTSD.
2020 Neurotoxicology Novel halogenated synthetic cannabinoids impair sensorimotor functions in mice.
2019 Cell Prolif CB1 enhanced the osteodentinogenic differentiation ability of periodontal ligament stem cells via p38 MAPK and JNK in an inflammatory environment.
2019 CNS Drugs Potential of Cannabinoid Receptor Ligands as Treatment for Substance Use Disorders.
2019 Sep Biomolecules Discovery of Orexant and Anorexant Agents with Indazole Scaffold Endowed with Peripheral Antiedema Activity.
2019 Biochemistry (Mosc) Analysis of Direct Effects of the CB1 Receptor Antagonist Rimonabant on Fatty Acid Oxidation and Glycogenolysis in Liver and Muscle Cells in vitro.
2019 Mol Pharmacol Probing the CB1 Cannabinoid Receptor Binding Pocket with AM6538, a High-Affinity Irreversible Antagonist.
2020 Stress Endocannabinoid signaling as an intrinsic component of the circuits mediating adaptive responses to repeated stress exposure in adult male sprague dawley rats.
2020 Jan J Ethnopharmacol Identification of novel phytocannabinoids from Ganoderma by label-free dynamic mass redistribution assay.
2019 Nov Biol Pharm Bull N-Linoleyltyrosine Protects against Transient Cerebral Ischemia in Gerbil via CB2 Receptor Involvement in PI3KAkt Signaling Pathway.
2019 J Cell Mol Med The cannabinoid receptor 1 is involved in renal fibrosis during chronic allograft dysfunction: Proof of concept.
2019 Biochim Biophys Acta Mol ... Anandamide targets aromatase: A breakthrough on human decidualization.
2019 Br J Pharmacol Δ8 -Tetrahydrocannabivarin has potent anti-nicotine effects in several rodent models of nicotine dependence.
2020 Br J Pharmacol Dual inhibition of cannabinoid CB1 receptor and inducible NOS attenuates obesity-induced chronic kidney disease.
2020 May Neuropharmacology Cannabidiol attenuates the rewarding effects of cocaine in rats by CB2, 5-HT1A and TRPV1 receptor mechanisms.
2019 Front Behav Neurosci Cannabidiol and the Remainder of the Plant Extract Modulate the Effects of Δ9-Tetrahydrocannabinol on Fear Memory Reconsolidation.
2019 Br J Pharmacol In vitro determination of the efficacy of illicit synthetic cannabinoids at CB1 receptors.
2019 Pharmacology Etomidate Modulates the Tactile Stimulation-Evoked Field Potential Responses in Cerebellar Granule Cell Layer in vivo in Mice.
2019 Oct Am J Physiol Endocrinol M... The TRPV1 channel regulates glucose metabolism.
2019 Mem Inst Oswaldo Cruz Cannabinoid receptor-1 antagonism: a new perspective on treating a murine schistosomal liver fibrosis model.
2019 J Orthop Res Dose-Dependent Cannabidiol-Induced Elevation of Intracellular Calcium and Apoptosis in Human Articular Chondrocytes.
2019 Br J Pharmacol Cannabichromene is a cannabinoid CB2 receptor agonist.