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Recent literature: CB1 receptor antagonist
Date Journal Article title
2019 Apr Psychopharmacology (Berl) Oleoyl glycine: interference with the aversive effects of acute naloxone-precipitated MWD, but not morphine reward, in male Sprague-Dawley rats.
2019 Biomed Pharmacother Ketamine-induced antidepressant like effects in mice: A possible involvement of cannabinoid system.
2019 Apr Cornea Evidence for a GPR18 Role in Chemotaxis, Proliferation, and the Course of Wound Closure in the Cornea.
2019 Front Pharmacol The Cannabinoid CB1 Antagonist TM38837 With Limited Penetrance to the Brain Shows Reduced Fear-Promoting Effects in Mice.
2019 Apr Inflammopharmacology Role of cannabinoid receptor 1 and the peroxisome proliferator-activated receptor α in mediating anti-nociceptive effects of synthetic cannabinoids and a cannabinoid-like compound.
2019 Curr Opin Rheumatol Joints for joints: cannabinoids in the treatment of rheumatoid arthritis.
2019 Mar ACS Chem Neurosci WIN 55,212-2 Reverted Pilocarpine-Induced Status Epilepticus Early Changes of the Interaction among 5-HT2CNMDACB1 Receptors in the Rat Hippocampus.
2019 Mar J Biol Chem Role of microRNA in CB1 antagonist-mediated regulation of adipose tissue macrophage polarization and chemotaxis during diet-induced obesity.
2019 Mar Brain Res Cannabidiol attenuates mechanical allodynia in streptozotocin-induced diabetic rats via serotonergic system activation through 5-HT1A receptors.
2019 Mar BMC Neurosci Additive effect of 5-HT2C and CB1 receptor blockade on the regulation of sleep-wake cycle.
2019 Expert Opin Ther Pat A patent update on cannabinoid receptor 1 antagonists (2015-2018).
2019 Mar Neurosci Lett The effect of the cannabinoid receptor agonist and antagonist on the light-induced changes in the rachiasmatic nucleus of rats.
2019 Int J Immunopathol Pharmacol Metformin inhibits both oleic acid-induced and CB1R receptor agonist-induced lipid accumulation in Hep3B cells: The preliminary report.
2019 Feb J Pharmacol Sci Indomethacin plus minocycline coadministration relieves chemotherapy and antiretroviral drug-induced neuropathic pain in a cannabinoid receptors-dependent manner.
2019 Mar Psychopharmacology (Berl) Effects of the synthetic cannabinoid 5F-AMB on anxiety and recognition memory in mice.
2019 Mar Neurosci Lett Cannabinoid CB1 receptors mediate the anxiolytic effects induced by systemic alprazolam and intra-periaqueductal gray 5-HT1A receptor activation.
2019 Mar Mol Neurobiol Cannabinoids Induce Cell Death and Promote P2X7 Receptor Signaling in Retinal Glial Progenitors in Culture.
2019 PeerJ Dual mechanism of TRKB activation by anandamide through CB1 and TRPV1 receptors.
2019 Feb Epilepsy Behav Activation of ATP-sensitive K-channel promotes the anticonvulsant properties of cannabinoid receptor agonist through mitochondrial ATP level reduction.
2019 Br J Pharmacol Cannabinoid CB1 and CB2 receptor mechanisms underlie cannabis reward and aversion in rats.
2019 Jun Brain Res Layer-specific involvement of endocannabinoid signaling in muscarinic-induced long-term depression in layer 23 pyramidal neurons of rat visual cortex.
2019 Feb Neurosci Lett Δ9-Tetrahydrocannabinol elicited 22-kHz ultrasonic vocalization changes after air puff stimulus through CB1 receptor in adult rats.
2019 Br J Pharmacol Cannabinoids differentially modulate cortical information transmission through the sensorimotor or medial prefrontal basal ganglia circuits.
2019 Neurobiol Dis Synergistic action of CB1 and 5-HT2B receptors in preventing pilocarpine-induced status epilepticus in rats.
2019 Apr Neurosci Lett Ketamine induces central antinociception mediated by endogenous cannabinoids and activation of CB1 receptors.
2019 Br J Pharmacol Opposite effects of cannabinoid CB1 and CB2 receptors on antipsychotic clozapine-induced cardiotoxicity.
2019 Jan Psychopharmacology (Berl) Opposing roles of dorsomedial hypothalamic CB1 and TRPV1 receptors in anandamide signaling during the panic-like response elicited in mice by Brazilian rainbow Boidae snakes.
2019 Jan Mol Neurobiol Targeting CB1 and GPR55 Endocannabinoid Receptors as a Potential Neuroprotective Approach for Parkinson's Disease.
2019 Pharmacology Blockade of Serotonin 2C Receptors with SB-242084 Moderates Reduced Locomotor Activity and Rearing by Cannabinoid 1 Receptor Antagonist AM-251.
2019 Jan Eur J Neurosci Caffeine and cannabinoid receptors modulate impulsive behavior in an animal model of attentional deficit and hyperactivity disorder.
2019 Apr Neurosci Lett Functional crosstalk of nucleus accumbens CB1 and OX2 receptors in response to nicotine-induced place preference.
2019 Jan Pain Hedonic drinking engages a ra-spinal inhibition of thermal nociception in adult rats.
2019 Curr Opin Lipidol Cannabis effects on lipoproteins.
2019 PLoS One Different temporal windows for CB1 receptor involvement in contextual fear memory destabilisation in the amygdala and hippocampus.
2019 Jan Cell Crystal Structure of the Human Cannabinoid Receptor CB2.
2018 Front Pharmacol Therapeutic Effect of the Substrate-Selective COX-2 Inhibitor IMMA in the Animal Model of Chronic Constriction Injury.
2019 Cell Mol Life Sci Multiple endocannabinoid-mediated mechanisms in the regulation of energy homeostasis in brain and peripheral tissues.
2019 Pharmacol Biochem Behav CB1 positive allosteric modulation attenuates Δ9-THC withdrawal and NSAID-induced gastric inflammation.
2019 Mol Reprod Dev Fibronectin modulates the endocannabinoid system through the cAMPPKA pathway during human sperm capacitation.
2019 Mar Neurosci Lett Inhibition of CB1 receptor ameliorates spatial learning and memory impairment in mice with traumatic brain injury.
2018 EXCLI J The role of CA1 CB1 receptors on lithium-induced spatial memory impairment in rats.
2019 Inflammation Cannabinoid CB1 Receptor Antagonist Rimonabant Decreases Levels of Markers of Organ Dysfunction and Alters Vascular Reactivity in Aortic Vessels in Late Sepsis in Rats.
2018 Front Psychiatry CB1 Agonism Alters Addiction-Related Behaviors in Mice Lacking Mu or Delta Opioid Receptors.
2019 Jan J Neurotrauma Therapeutic Effect of a Novel Fatty Acid Amide Hydrolase Inhibitor PF04457845 in the Repetitive Closed Head Injury Mouse Model.
2019 Hepatology Cannabinoid-1 Receptor Antagonism Improves Glycemic Control and Increases Energy Expenditure Through Sirtuin-1Mechanistic Target of Rapamycin Complex 2 and 5'Adenosine Monophosphate-Activated Protein Kinase Signaling.
2019 Feb Physiol Behav Cannabinoid receptor type-1 partially mediates metabolic endotoxemia-induced inflammation and insulin resistance.
2018 Physiol Rep Activity in nodose ganglia neurons after treatment with CP 55,940 and cholecystokinin.
2019 Mol Pharmacol Cannabinoid CB2 Agonist AM1710 Differentially Suppresses Distinct Pathological Pain States and Attenuates Morphine Tolerance and Withdrawal.
2019 Mar Neuropharmacology Peripubertal cannabidiol treatment rescues behavioral and neurochemical abnormalities in the MAM model of schizophrenia.
2019 Feb Int J Neuropsychopharmacol Inhibition of Monoacylglycerol Lipase Reduces the Reinstatement of Methamphetamine-Seeking and Anxiety-Like Behaviors in Methamphetamine Self-Administered Rats.
2019 J Cell Physiol Central adiponectin induces trabecular bone mass partly through epigenetic downregulation of cannabinoid receptor CB1.
2018 Lipids Anandamide Induces Platelet Nitric Oxide Synthase through AMP-Activated Protein Kinase.
2018 Nov Psychopharmacology (Berl) Cannabinoid-induced lower lip retraction in rats.
2019 Feb Behav Brain Res Sexual interaction is essential for the transformation of non-copulating rats into sexually active animals by the endocannabinoid anandamide.
2018 J Recept Signal Transduct... Investigation of non-CB1, non-CB2 WIN55212-2-sensitive G-protein-coupled receptors in the brains of mammals, birds, and amphibians.
2018 PLoS One CB1 receptor blockade ameliorates hepatic fat infiltration and inflammation and increases Nrf2-AMPK pathway in a rat model of severely uncontrolled diabetes.
2018 Oct Synapse Endogenous cannabinoids mediate the effect of BDNF at CA1 inhibitory synapses in the hippocampus.
2018 Nov Neuroscience Medial Prefrontal Cortical Cannabinoid CB1 Receptors Mediate Morphine-Dextromethorphan Cross State-Dependent Memory: The Involvement of BDNFcFOS Signaling Pathways.
2018 Pharmacol Rep Endocannabinoid-mediated modulation of Gq protein-coupled receptor mediates vascular hyporeactivity to nor-adrenaline during polymicrobial sepsis.
2018 Pharmacol Rep The role of (E)-6-chloro-3-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-2-styrylquinazolin-4(3H)-one in the modulation of cannabinoidergic system. A pilot study.
2018 Nov Drug Alcohol Depend Assessment of rimonabant-like adverse effects of purported CB1R neutral antagonist CB2R agonist aminoalkylindole derivatives in mice.
2018 Nov Life Sci Cannabinoids in depressive disorders.
2018 J Pharmacol Exp Ther Brain-Permeant and -Impermeant Inhibitors of Fatty Acid Amide Hydrolase Synergize with the Opioid Analgesic Morphine to Suppress Chemotherapy-Induced Neuropathic Nociception Without Enhancing Effects of Morphine on Gastrointestinal Transit.
2018 Sep Nat Commun Genetic and pharmacological regulation of the endocannabinoid CB1 receptor in Duchenne muscular dystrophy.
2018 Eur Neuropsychopharmacol Prenatal immune activation potentiates endocannabinoid-related plasticity of inhibitory synapses in the hippocampus of adolescent rat offspring.
2018 Psychopharmacology (Berl) Effects of fatty acid amide hydrolase inhibitor URB597 in a rat model of trauma-induced long-term anxiety.
2018 Biochem Pharmacol Role of the endocannabinoid system in drug addiction.
2019 Acta Pharmacol Sin Heterogeneity of cannabinoid ligand-induced modulations in intracellular Ca2+ signals of mouse pancreatic acinar cells in vitro.
2018 Biochem Pharmacol PPARαCB1 receptor dual ligands as a novel therapy for alcohol use disorder: Evaluation of a novel oleic acid conjugate in preclinical rat models.
2018 Neuropharmacology Conditioned gaping produced by high dose Δ9-tetrahydracannabinol: Dysregulation of the hypothalamic endocannabinoid system.
2019 Jan ACS Chem Neurosci Diarylureas Containing 5-Membered Heterocycles as CB1 Receptor Allosteric Modulators: Design, Synthesis, and Pharmacological Evaluation.
2018 Br J Pharmacol Reversal of albuminuria by combined AM6545 and perindopril therapy in experimental diabetic nephropathy.
2018 Epilepsy Behav Acute foot-shock stress decreased seizure susceptibility against pentylenetetrazole-induced seizures in mice: Interaction between endogenous opioids and cannabinoids.
2018 Brain Res Bull Modulatory role of the intra-accumbal CB1 receptor in protein level of the c-fos and pCREBCREB ratio in the nucleus accumbens and ventral tegmental area in extinction and morphine seeking in the rats.