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Recent literature: CB1 receptor antagonist
Date Journal Article title
2019 Aug Neuropharmacology Cannabidiol attenuates the rewarding effects of cocaine in rats by CB2, 5-TH1A and TRPV1 receptor mechanisms.
2019 Front Behav Neurosci Cannabidiol and the Remainder of the Plant Extract Modulate the Effects of Δ9-Tetrahydrocannabinol on Fear Memory Reconsolidation.
2019 Aug Br J Pharmacol In vitro determination of the CB1 efficacy of illicit synthetic cannabinoids.
2019 Aug Pharmacology Etomidate Modulates the Tactile Stimulation-Evoked Field Potential Responses in Cerebellar Granule Cell Layer in vivo in Mice.
2019 Mem Inst Oswaldo Cruz Cannabinoid receptor-1 antagonism: a new perspective on treating a murine schistosomal liver fibrosis model.
2019 Aug J Orthop Res Dose-dependent cannabidiol-induced elevation of intracellular calcium and apoptosis in human articular chondrocytes.
2019 Aug Br J Pharmacol Cannabichromene is a cannabinoid CB2 receptor agonist.
2019 Adv Exp Med Biol Cannabinoid Interactions with Proteins: Insights from Structural Studies.
2019 Sep Life Sci Evaluation of protective effects of non-selective cannabinoid receptor agonist WIN 55,212-2 against the nitroglycerine-induced acute and chronic animal models of migraine: A mechanistic study.
2019 Jul Daru Cannabinoid system involves in the analgesic effect of protocatechuic acid.
2019 Front Cell Neurosci A Nitric Oxide-Dependent Presynaptic LTP at Glutamatergic Synapses of the PVN Magnocellular Neurosecretory Cells iin vitroi in Rats.
2019 Aug Bioorg Med Chem Functionalized 6-(piperidin-1-yl)-8,9-diphenyl purines as inverse agonists of the CB1 receptor - SAR efforts towards selectivity and peripheralization.
2019 Jul Neurotox Res A Cannabinoid Receptor-Mediated Mechanism Participates in the Neuroprotective Effects of Oleamide Against Excitotoxic Damage in Rat Brain Synaptosomes and Cortical Slices.
2019 Jul Curr Top Med Chem Overcoming the psychiatric side effects of the cannabinoid CB1 receptor antagonists: Current approaches for therapeutics development.
2019 Front Physiol Cannabinoid CB1 Receptors Inhibit Gut-Brain Satiation Signaling in Diet-Induced Obesity.
2019 Jul Sci Rep Elevation of endocannabinoids in the brain by synthetic cannabinoid JWH-018: mechanism and effect on learning and memory.
2019 Jun ACS Pharmacol Transl Sci mGlu5 Positive Allosteric Modulators Facilitate Long-Term Potentiation via Disinhibition Mediated by mGlu5-Endocannabinoid Signaling.
2019 Jun Am J Physiol Endocrinol M... Activation of NPRs and UCP1-independent pathway following CB1R antagonist treatment is associated with adipose tissue beiging in fat-fed male dogs.
2019 Oct Toxicol Lett Quetiapine induces myocardial necroptotic cell death through bidirectional regulation of cannabinoid receptors.
2019 Jun Addict Biol Cannabidiol inhibits sucrose self-administration by CB1 and CB2 receptor mechanisms in rodents.
2019 Pharmacol Biochem Behav A medium throughput rodent model of relapse from addiction with behavioral and pharmacological specificity.
2019 Exp Eye Res Endogenous and synthetic cannabinoids induce the downregulation of cannabinoid CB1 receptor in retina.
2019 Front Physiol Is Experimental Evolution of an Increased Aerobic Exercise Performance in Bank Voles Mediated by Endocannabinoid Signaling Pathway?
2019 Front Pharmacol CUMYL-4CN-BINACA Is an Efficacious and Potent Pro-Convulsant Synthetic Cannabinoid Receptor Agonist.
2019 May Clin Nutr Resveratrol attenuates high-fat diet-induced non-alcoholic steatohepatitis by maintaining gut barrier integrity and inhibiting gut inflammation through regulation of the endocannabinoid system.
2019 Mol Med Rep Electroacupuncture alleviates morphine‑induced hyperalgesia by regulating spinal CB1 receptors and ERK12 activity.
2019 Front Immunol Cannabinoid Receptor 1 Blockade Attenuates Obesity and Adipose Tissue Type 1 Inflammation Through miR-30e-5p Regulation of Delta-Like-4 in Macrophages and Consequently Downregulation of Th1 Cells.
2019 May Int J Mol Sci Endocannabinoid System in Hepatic Glucose Metabolism, Fatty Liver Disease, and Cirrhosis.
2019 Jul Neurosci Lett CB1R mediates oleamide's reward while 5HT2cR mediates aversion in the nucleus accumbens shell of rats.
2019 Biomed Pharmacother The role of 2-arachidonoylglycerol in the regulation of the tumor-immune microenvironment in murine models of pancreatic cancer.
2019 Aug Prog Neuropsychopharmacol... Cannabidiol attenuates aggressive behavior induced by social isolation in mice: Involvement of 5-HT1A and CB1 receptors.
2019 Apr Molecules Development of Oxygen-Bridged Pyrazole-Based Structures as Cannabinoid Receptor 1 Ligands.
2019 Cannabis Cannabinoid Res Systemic Blockade of the CB1 Receptor Augments Hippocampal Gene Expression Involved in Synaptic Plasticity but Perturbs Hippocampus-Dependent Learning Task.
2019 Jun Drug Alcohol Depend Self-administration of edible Δ9-tetrahydrocannabinol and associated behavioral effects in mice.
2019 Pain Hedonic drinking engages a raspinal inhibition of thermal nociception in adult rats.
2019 Psychopharmacology (Berl) Oleoyl glycine: interference with the aversive effects of acute naloxone-precipitated MWD, but not morphine reward, in male Sprague-Dawley rats.
2019 Apr Molecules Hippocampal Stratum Oriens Somatostatin-Positive Cells Undergo CB1-Dependent Long-Term Potentiation and Express Endocannabinoid Biosynthetic Enzymes.
2019 Biomed Pharmacother Ketamine-induced antidepressant like effects in mice: A possible involvement of cannabinoid system.
2019 Cornea Evidence for a GPR18 Role in Chemotaxis, Proliferation, and the Course of Wound Closure in the Cornea.
2019 Front Pharmacol The Cannabinoid CB1 Antagonist TM38837 With Limited Penetrance to the Brain Shows Reduced Fear-Promoting Effects in Mice.
2019 Apr Inflammopharmacology Role of cannabinoid receptor 1 and the peroxisome proliferator-activated receptor α in mediating anti-nociceptive effects of synthetic cannabinoids and a cannabinoid-like compound.
2019 Curr Opin Rheumatol Joints for joints: cannabinoids in the treatment of rheumatoid arthritis.
2019 Jul ACS Chem Neurosci WIN 55,212-2 Reverted Pilocarpine-Induced Status Epilepticus Early Changes of the Interaction among 5-HT2CNMDACB1 Receptors in the Rat Hippocampus.
2019 May J Biol Chem Role of microRNA in CB1 antagonist-mediated regulation of adipose tissue macrophage polarization and chemotaxis during diet-induced obesity.
2019 Jul Brain Res Cannabidiol attenuates mechanical allodynia in streptozotocin-induced diabetic rats via serotonergic system activation through 5-HT1A receptors.
2019 Mar BMC Neurosci Additive effect of 5-HT2C and CB1 receptor blockade on the regulation of sleep-wake cycle.
2019 Expert Opin Ther Pat A patent update on cannabinoid receptor 1 antagonists (2015-2018).
2019 Jun Neurosci Lett The effect of the cannabinoid receptor agonist and antagonist on the light-induced changes in the rachiasmatic nucleus of rats.
2019 Int J Immunopathol Pharmacol Metformin inhibits both oleic acid-induced and CB1R receptor agonist-induced lipid accumulation in Hep3B cells: The preliminary report.
2019 J Pharmacol Sci Indomethacin plus minocycline coadministration relieves chemotherapy and antiretroviral drug-induced neuropathic pain in a cannabinoid receptors-dependent manner.
2019 Psychopharmacology (Berl) Effects of the synthetic cannabinoid 5F-AMB on anxiety and recognition memory in mice.
2019 Jun Neurosci Lett Cannabinoid CB1 receptors mediate the anxiolytic effects induced by systemic alprazolam and intra-periaqueductal gray 5-HT1A receptor activation.
2019 Mol Neurobiol Cannabinoids Induce Cell Death and Promote P2X7 Receptor Signaling in Retinal Glial Progenitors in Culture.
2019 PeerJ Dual mechanism of TRKB activation by anandamide through CB1 and TRPV1 receptors.
2019 Epilepsy Behav Activation of ATP-sensitive K-channel promotes the anticonvulsant properties of cannabinoid receptor agonist through mitochondrial ATP level reduction.
2019 Br J Pharmacol Cannabinoid CB1 and CB2 receptor mechanisms underlie cannabis reward and aversion in rats.
2019 Jun Brain Res Layer-specific involvement of endocannabinoid signaling in muscarinic-induced long-term depression in layer 23 pyramidal neurons of rat visual cortex.
2019 May Neurosci Lett Δ9-Tetrahydrocannabinol elicited 22-kHz ultrasonic vocalization changes after air puff stimulus through CB1 receptor in adult rats.
2019 Br J Pharmacol Cannabinoids differentially modulate cortical information transmission through the sensorimotor or medial prefrontal basal ganglia circuits.
2019 Neurobiol Dis Synergistic action of CB1 and 5-HT2B receptors in preventing pilocarpine-induced status epilepticus in rats.
2019 Apr Neurosci Lett Ketamine induces central antinociception mediated by endogenous cannabinoids and activation of CB1 receptors.
2019 Br J Pharmacol Opposite effects of cannabinoid CB1 and CB2 receptors on antipsychotic clozapine-induced cardiotoxicity.
2019 Psychopharmacology (Berl) Opposing roles of dorsomedial hypothalamic CB1 and TRPV1 receptors in anandamide signaling during the panic-like response elicited in mice by Brazilian rainbow Boidae snakes.
2019 Mol Neurobiol Targeting CB1 and GPR55 Endocannabinoid Receptors as a Potential Neuroprotective Approach for Parkinson's Disease.
2019 Pharmacology Blockade of Serotonin 2C Receptors with SB-242084 Moderates Reduced Locomotor Activity and Rearing by Cannabinoid 1 Receptor Antagonist AM-251.
2019 Eur J Neurosci Caffeine and cannabinoid receptors modulate impulsive behavior in an animal model of attentional deficit and hyperactivity disorder.
2019 Apr Neurosci Lett Functional crosstalk of nucleus accumbens CB1 and OX2 receptors in response to nicotine-induced place preference.
2019 Jan Pain Hedonic drinking engages a ra-spinal inhibition of thermal nociception in adult rats.
2019 Curr Opin Lipidol Cannabis effects on lipoproteins.
2019 PLoS One Different temporal windows for CB1 receptor involvement in contextual fear memory destabilisation in the amygdala and hippocampus.
2019 Jan Cell Crystal Structure of the Human Cannabinoid Receptor CB2.
2018 Front Pharmacol Therapeutic Effect of the Substrate-Selective COX-2 Inhibitor IMMA in the Animal Model of Chronic Constriction Injury.
2019 Cell Mol Life Sci Multiple endocannabinoid-mediated mechanisms in the regulation of energy homeostasis in brain and peripheral tissues.
2019 Pharmacol Biochem Behav CB1 positive allosteric modulation attenuates Δ9-THC withdrawal and NSAID-induced gastric inflammation.
2019 Mol Reprod Dev Fibronectin modulates the endocannabinoid system through the cAMPPKA pathway during human sperm capacitation.