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Recent literature: CB1 receptor antagonist
Date Journal Article title
2019 Feb Br J Pharmacol Cannabinoid CB1 and CB2 receptor mechanisms underlie cannabis reward and aversion in rats.
2019 Feb Brain Res Layer-specific involvement of endocannabinoid signaling in muscarinic-induced long-term depression in layer 23 pyramidal neurons of rat visual cortex.
2019 Feb Neurosci Lett Δ9-Tetrahydrocannabinol elicited 22-kHz ultrasonic vocalization changes after air puff stimulus through CB1 receptor in adult rats.
2019 Feb Br J Pharmacol Cannabinoids differentially modulate the cortical information transmission through the sensorimotor or medial prefrontal basal ganglia circuits.
2019 Feb Neurobiol Dis Synergistic action of CB1 and 5-HT2B receptors in preventing pilocarpine-induced status epilepticus in rats.
2019 Feb Neurosci Lett Ketamine induces central antinociception mediated by endogenous cannabinoids and activation of CB1 receptors.
2019 Feb Br J Pharmacol Opposite effects of cannabinoid CB1 and CB2 receptors on antipsychotic clozapine-induced cardiotoxicity.
2019 Jan Psychopharmacology (Berl) Opposing roles of dorsomedial hypothalamic CB1 and TRPV1 receptors in anandamide signaling during the panic-like response elicited in mice by Brazilian rainbow Boidae snakes.
2019 Jan Mol Neurobiol Targeting CB1 and GPR55 Endocannabinoid Receptors as a Potential Neuroprotective Approach for Parkinson's Disease.
2019 Jan Pharmacology Blockade of Serotonin 2C Receptors with SB-242084 Moderates Reduced Locomotor Activity and Rearing by Cannabinoid 1 Receptor Antagonist AM-251.
2019 Jan Eur J Neurosci Caffeine and cannabinoid receptors modulate impulsive behavior in an animal model of attentional deficit and hyperactivity disorder.
2019 Jan Neurosci Lett Functional crosstalk of nucleus accumbens CB1 and OX2 receptors in response to nicotine-induced place preference.
2019 Jan Pain Hedonic drinking engages a ra-spinal inhibition of thermal nociception in adult rats.
2019 Jan Curr Opin Lipidol Cannabis effects on lipoproteins.
2019 PLoS One Different temporal windows for CB1 receptor involvement in contextual fear memory destabilisation in the amygdala and hippocampus.
2019 Jan Cell Crystal Structure of the Human Cannabinoid Receptor CB2.
2018 Front Pharmacol Therapeutic Effect of the Substrate-Selective COX-2 Inhibitor IMMA in the Animal Model of Chronic Constriction Injury.
2019 Jan Cell Mol Life Sci Multiple endocannabinoid-mediated mechanisms in the regulation of energy homeostasis in brain and peripheral tissues.
2019 Pharmacol Biochem Behav CB1 positive allosteric modulation attenuates Δ9-THC withdrawal and NSAID-induced gastric inflammation.
2019 Mol Reprod Dev Fibronectin modulates the endocannabinoid system through the cAMPPKA pathway during human sperm capacitation.
2018 Dec Neurosci Lett Inhibition of CB1 receptor ameliorates spatial learning and memory impairment in mice with traumatic brain injury.
2018 EXCLI J The role of CA1 CB1 receptors on lithium-induced spatial memory impairment in rats.
2018 Dec Inflammation Cannabinoid CB1 Receptor Antagonist Rimonabant Decreases Levels of Markers of Organ Dysfunction and Alters Vascular Reactivity in Aortic Vessels in Late Sepsis in Rats.
2018 Front Psychiatry CB1 Agonism Alters Addiction-Related Behaviors in Mice Lacking Mu or Delta Opioid Receptors.
2019 Jan J Neurotrauma Therapeutic Effect of a Novel Fatty Acid Amide Hydrolase Inhibitor PF04457845 in the Repetitive Closed Head Injury Mouse Model.
2018 Dec Hepatology Cannabinoid-1 Receptor Antagonism Improves Glycemic Control and Increases Energy Expenditure via Sirt1mTORC2 and AMPK Signaling.
2019 Feb Physiol Behav Cannabinoid receptor type-1 partially mediates metabolic endotoxemia-induced inflammation and insulin resistance.
2018 Physiol Rep Activity in nodose ganglia neurons after treatment with CP 55,940 and cholecystokinin.
2019 Mol Pharmacol Cannabinoid CB2 Agonist AM1710 Differentially Suppresses Distinct Pathological Pain States and Attenuates Morphine Tolerance and Withdrawal.
2019 Mar Neuropharmacology Peripubertal cannabidiol treatment rescues behavioral and neurochemical abnormalities in the MAM model of schizophrenia.
2019 Feb Int J Neuropsychopharmacol Inhibition of Monoacylglycerol Lipase Reduces the Reinstatement of Methamphetamine-Seeking and Anxiety-Like Behaviors in Methamphetamine Self-Administered Rats.
2019 J Cell Physiol Central adiponectin induces trabecular bone mass partly through epigenetic downregulation of cannabinoid receptor CB1.
2018 Lipids Anandamide Induces Platelet Nitric Oxide Synthase through AMP-Activated Protein Kinase.
2018 Nov Psychopharmacology (Berl) Cannabinoid-induced lower lip retraction in rats.
2019 Feb Behav Brain Res Sexual interaction is essential for the transformation of non-copulating rats into sexually active animals by the endocannabinoid anandamide.
2018 J Recept Signal Transduct... Investigation of non-CB1, non-CB2 WIN55212-2-sensitive G-protein-coupled receptors in the brains of mammals, birds, and amphibians.
2018 PLoS One CB1 receptor blockade ameliorates hepatic fat infiltration and inflammation and increases Nrf2-AMPK pathway in a rat model of severely uncontrolled diabetes.
2018 Oct Synapse Endogenous cannabinoids mediate the effect of BDNF at CA1 inhibitory synapses in the hippocampus.
2018 Nov Neuroscience Medial Prefrontal Cortical Cannabinoid CB1 Receptors Mediate Morphine-Dextromethorphan Cross State-Dependent Memory: The Involvement of BDNFcFOS Signaling Pathways.
2018 Pharmacol Rep Endocannabinoid-mediated modulation of Gq protein-coupled receptor mediates vascular hyporeactivity to nor-adrenaline during polymicrobial sepsis.
2018 Pharmacol Rep The role of (E)-6-chloro-3-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-2-styrylquinazolin-4(3H)-one in the modulation of cannabinoidergic system. A pilot study.
2018 Nov Life Sci Cannabinoids in depressive disorders.
2018 J Pharmacol Exp Ther Brain-Permeant and -Impermeant Inhibitors of Fatty Acid Amide Hydrolase Synergize with the Opioid Analgesic Morphine to Suppress Chemotherapy-Induced Neuropathic Nociception Without Enhancing Effects of Morphine on Gastrointestinal Transit.
2018 Sep Nat Commun Genetic and pharmacological regulation of the endocannabinoid CB1 receptor in Duchenne muscular dystrophy.
2018 Eur Neuropsychopharmacol Prenatal immune activation potentiates endocannabinoid-related plasticity of inhibitory synapses in the hippocampus of adolescent rat offspring.
2018 Psychopharmacology (Berl) Effects of fatty acid amide hydrolase inhibitor URB597 in a rat model of trauma-induced long-term anxiety.
2018 Biochem Pharmacol Role of the endocannabinoid system in drug addiction.
2019 Acta Pharmacol Sin Heterogeneity of cannabinoid ligand-induced modulations in intracellular Ca2+ signals of mouse pancreatic acinar cells in vitro.
2018 Biochem Pharmacol PPARαCB1 receptor dual ligands as a novel therapy for alcohol use disorder: Evaluation of a novel oleic acid conjugate in preclinical rat models.
2018 Neuropharmacology Conditioned gaping produced by high dose Δ9-tetrahydracannabinol: Dysregulation of the hypothalamic endocannabinoid system.
2018 Sep ACS Chem Neurosci Diarylureas Containing 5-Membered Heterocycles as CB1 Receptor Allosteric Modulators: Design, Synthesis, and Pharmacological Evaluation.
2018 Br J Pharmacol Reversal of albuminuria by combined AM6545 and perindopril therapy in experimental diabetic nephropathy.
2018 Epilepsy Behav Acute foot-shock stress decreased seizure susceptibility against pentylenetetrazole-induced seizures in mice: Interaction between endogenous opioids and cannabinoids.
2018 Brain Res Bull Modulatory role of the intra-accumbal CB1 receptor in protein level of the c-fos and pCREBCREB ratio in the nucleus accumbens and ventral tegmental area in extinction and morphine seeking in the rats.
2019 Pain Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain.
2018 Front Psychiatry Reducing Effect of Saikosaponin A, an Active Ingredient of iBupleurum falcatumi, on Intake of Highly Palatable Food in a Rat Model of Overeating.
2018 Oct Eur J Pharmacol The novel peripherally active cannabinoid type 1 and serotonin type 3 receptor agonist AM9405 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome.
2018 Aug Br J Pharmacol Opposing roles of CB1 and CB2 cannabinoid receptors in the stimulant and rewarding effects of cocaine.
2018 Oct J Pharm Biomed Anal Simultaneous quantification of cannabinoids tetrahydrocannabinol, cannabidiol and CB1 receptor antagonist in rat plasma: An application to characterize pharmacokinetics after passive cannabis smoke inhalation and co-administration of rimonabant.
2018 Aug Bioorg Med Chem Synthesis and pharmacological characterization of functionalized 6-piperazin-1-yl-purines as cannabinoid receptor 1 (CB1) inverse agonists.
2018 Int J Dev Neurosci Sex-specific effects of CB1 receptor antagonism and stress in adolescence on anxiety, corticosterone concentrations, and contextual fear in adulthood in rats.
2018 Sep Neuropharmacology Pharmacological modulation of colorectal distension evoked potentials in conscious rats.
2018 Jul Br J Pharmacol Endocannabinoid regulation of homeostatic feeding and stress-induced alterations in food intake in male rats.
2018 CNS Drugs Role of the Endocannabinoid System in the Pathophysiology of Schizophrenia: Implications for Pharmacological Intervention.
2018 Sep Neurosci Lett Effects of concurrent blockade of OX2 and CB1 receptors in the ventral tegmental area on nicotine-induced place preference in rats.
2018 Epilepsy Res TRPV1 mediates the anticonvulsant effects of acetaminophen in mice.
2019 Acta Pharmacol Sin Developmental and behavioral effects in neonatal and adult mice following prenatal activation of endocannabinoid receptors by capsaicin.
2018 Neurochem Res Effects of rTMS on Hippocampal Endocannabinoids and Depressive-like Behaviors in Adolescent Rats.
2018 Jul Br J Pharmacol Allosteric and orthosteric pharmacology of cannabidiol and cannabidiol-dimethylheptyl at the type 1 and type 2 cannabinoid receptors.
2018 Neuropsychopharmacology Role of endocannabinoids in the hippocampus and amygdala in emotional memory and plasticity.
2018 Jul Sci Rep New βN-octadecanoyl-5-hydroxytryptamide: antinociceptive effect and possible mechanism of action in mice.
2019 Acta Pharmacol Sin Cannabinoid CB1 receptor neutral antagonist AM4113 inhibits heroin self-administration without depressive side effects in rats.
2018 Neuropsychopharmacology Opposing actions of CRF-R1 and CB1 receptors on VTA-GABAergic plasticity following chronic exposure to ethanol.
2018 Sep Neurosci Lett Orexin A presynaptically decreases inhibitory synaptic transmission in rat locus coeruleus neurons.